Design of Novel Exendin-Based Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonists
Evers, Andreas, Haack, Torsten, Lorenz, Martin, Bossart, Martin, Elvert, Ralf, Henkel, Bernd, Stengelin, Siegfried, Kurz, Michael, Glien, Maike, Dudda, Angela, Lorenz, Katrin, Kadereit, Dieter, Wagner, Michael
Published in Journal of medicinal chemistry (25.05.2017)
Published in Journal of medicinal chemistry (25.05.2017)
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Beyond bispecificity: Controlled Fab arm exchange for the generation of antibodies with multiple specificities
Yanakieva, Desislava, Pekar, Lukas, Evers, Andreas, Fleischer, Markus, Keller, Stephan, Mueller-Pompalla, Dirk, Toleikis, Lars, Kolmar, Harald, Zielonka, Stefan, Krah, Simon
Published in mAbs (2022)
Published in mAbs (2022)
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A library approach for the de novo high-throughput isolation of humanized VHH domains with favorable developability properties following camelid immunization
Arras, Paul, Yoo, Han Byul, Pekar, Lukas, Schröter, Christian, Clarke, Thomas, Krah, Simon, Klewinghaus, Daniel, Siegmund, Vanessa, Evers, Andreas, Zielonka, Stefan
Published in mAbs (31.12.2023)
Published in mAbs (31.12.2023)
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Journal Article
Cattle-derived knob paratopes grafted onto peripheral loops of the IgG1 Fc region enable the generation of a novel symmetric bispecific antibody format
Yanakieva, Desislava, Vollmer, Lena, Evers, Andreas, Siegmund, Vanessa, Arras, Paul, Pekar, Lukas, Doerner, Achim, Valldorf, Bernhard, Kolmar, Harald, Zielonka, Stefan, Krah, Simon
Published in Frontiers in immunology (24.10.2023)
Published in Frontiers in immunology (24.10.2023)
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Journal Article
Engineering hydrophobicity and manufacturability for optimized biparatopic antibody-drug conjugates targeting c-MET
Evers, Andreas, Krah, Simon, Demir, Deniz, Gaa, Ramona, Elter, Desislava, Schroeter, Christian, Zielonka, Stefan, Rasche, Nicolas, Dotterweich, Julia, Knuehl, Christine, Doerner, Achim
Published in mAbs (2024)
Published in mAbs (2024)
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Running on mixed fuel‐dual agonistic approach of GLP‐1 and GCG receptors leads to beneficial impact on body weight and blood glucose control: A comparative study between mice and non‐human primates
Elvert, Ralf, Herling, Andreas W., Bossart, Martin, Weiss, Tilo, Zhang, Baohong, Wenski, Pierre, Wandschneider, Jörn, Kleutsch, Sabrina, Butty, Uwe, Kannt, Aimo, Wagner, Michael, Haack, Torsten, Evers, Andreas, Dudda, Angela, Lorenz, Martin, Keil, Stefanie, Larsen, Philip J.
Published in Diabetes, obesity & metabolism (01.08.2018)
Published in Diabetes, obesity & metabolism (01.08.2018)
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Impact of antibody architecture and paratope valency on effector functions of bispecific NKp30 x EGFR natural killer cell engagers
Boje, Ammelie Svea, Pekar, Lukas, Koep, Katharina, Lipinski, Britta, Rabinovich, Brian, Evers, Andreas, Gehlert, Carina Lynn, Krohn, Steffen, Xiao, Yanping, Krah, Simon, Zaynagetdinov, Rinat, Toleikis, Lars, Poetzsch, Sven, Peipp, Matthias, Zielonka, Stefan, Klausz, Katja
Published in mAbs (2024)
Published in mAbs (2024)
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Generation and engineering of potent single domain antibody-based bispecific IL-18 mimetics resistant to IL-18BP decoy receptor inhibition
Lipinski, Britta, Unmuth, Laura, Arras, Paul, Becker, Stefan, Bauer, Christina, Toleikis, Lars, Krah, Simon, Doerner, Achim, Yanakieva, Desislava, Boje, Ammelie Svea, Klausz, Katja, Peipp, Matthias, Siegmund, Vanessa, Evers, Andreas, Kolmar, Harald, Pekar, Lukas, Zielonka, Stefan
Published in mAbs (2023)
Published in mAbs (2023)
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Journal Article
Team Players or Opponents: Coadministration of Selective Glucagon and GLP-1 Receptor Agonists in Obese Diabetic Monkeys
Elvert, Ralf, Bossart, Martin, Herling, Andreas W, Weiss, Tilo, Zhang, Baohong, Kannt, Aimo, Wagner, Michael, Haack, Torsten, Evers, Andreas, Dudda, Angela, Keil, Stefanie, Lorenz, Martin, Lorenz, Katrin, Riz, Michela, Hennerici, Wolfgang, Larsen, Philip J
Published in Endocrinology (Philadelphia) (01.08.2018)
Published in Endocrinology (Philadelphia) (01.08.2018)
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Journal Article
AI/ML combined with next-generation sequencing of VHH immune repertoires enables the rapid identification of de novo humanized and sequence-optimized single domain antibodies: a prospective case study
Arras, Paul, Yoo, Han Byul, Pekar, Lukas, Clarke, Thomas, Friedrich, Lukas, Schröter, Christian, Schanz, Jennifer, Tonillo, Jason, Siegmund, Vanessa, Doerner, Achim, Krah, Simon, Guarnera, Enrico, Zielonka, Stefan, Evers, Andreas
Published in Frontiers in molecular biosciences (28.09.2023)
Published in Frontiers in molecular biosciences (28.09.2023)
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A Conserved Hydrophobic Moiety and Helix-Helix Interactions Drive the Self-Assembly of the Incretin Analog Exendin-4
Wolff, Martin, Gast, Klaus, Evers, Andreas, Kurz, Michael, Pfeiffer-Marek, Stefania, Schüler, Anja, Seckler, Robert, Thalhammer, Anja
Published in Biomolecules (Basel, Switzerland) (03.09.2021)
Published in Biomolecules (Basel, Switzerland) (03.09.2021)
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Journal Article
First-in-class positron emission tomography tracer for the glucagon receptor
Velikyan, Irina, Haack, Torsten, Bossart, Martin, Evers, Andreas, Laitinen, Iina, Larsen, Philip, Plettenburg, Oliver, Johansson, Lars, Pierrou, Stefan, Wagner, Michael, Eriksson, Olof
Published in EJNMMI research (15.02.2019)
Published in EJNMMI research (15.02.2019)
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Journal Article
Phototoxicity – from molecular descriptors to classification models
Schmidt, Friedemann, Evers, Andreas, Amberg, Alexander, Hessler, Gerhard, Robles, Catherine, Baringhaus, Karl-Heinz
Published in Journal of cheminformatics (19.04.2011)
Published in Journal of cheminformatics (19.04.2011)
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