Synthesis and biological properties of bioreductively targeted nitrothienyl prodrugs of combretastatin A-4
Thomson, Peter, Naylor, Matthew A, Everett, Steven A, Stratford, Michael R L, Lewis, Gemma, Hill, Sally, Patel, Kantilal B, Wardman, Peter, Davis, Peter D
Published in Molecular cancer therapeutics (01.11.2006)
Published in Molecular cancer therapeutics (01.11.2006)
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Journal Article
Bioreductive Activation of a Series of Indolequinones by Human DT-Diaphorase: Structure−Activity Relationships
Phillips, Roger M, Naylor, Matthew A, Jaffar, Mohammed, Doughty, Stephen W, Everett, Steven A, Breen, Anthony G, Choudry, Guzanfar A, Stratford, Ian J
Published in Journal of medicinal chemistry (07.10.1999)
Published in Journal of medicinal chemistry (07.10.1999)
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Journal Article
Modifying rates of reductive elimination of leaving groups from indolequinone prodrugs: a key factor in controlling hypoxia-selective drug release
Everett, Steven A., Swann, Elizabeth, Naylor, Matthew A., Stratford, Michael R.L., Patel, Kantilal B., Tian, Natasha, Newman, Robert G., Vojnovic, Borivoj, Moody, Christopher J., Wardman, Peter
Published in Biochemical pharmacology (01.05.2002)
Published in Biochemical pharmacology (01.05.2002)
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Journal Article
Indolequinone Antitumor Agents: Reductive Activation and Elimination from (5-Methoxy-1-methyl-4,7-dioxoindol-3-yl)methyl Derivatives and Hypoxia-Selective Cytotoxicity in Vitro
Naylor, Matthew A, Swann, Elizabeth, Everett, Steven A, Jaffar, Mohammed, Nolan, John, Robertson, Naomi, Lockyer, Stacey D, Patel, Kantilal B, Dennis, Madeleine F, Stratford, Michael R. L, Wardman, Peter, Adams, Gerald E, Moody, Christopher J, Stratford, Ian J
Published in Journal of medicinal chemistry (16.07.1998)
Published in Journal of medicinal chemistry (16.07.1998)
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Journal Article
Comparative mechanisms and rates of free radical scavenging by carotenoid antioxidants
Mortensen, Alan, Skibsted, Leif H., Sampson, Julia, Rice-Evans, Catherine, Everett, Steven A.
Published in FEBS letters (24.11.1997)
Published in FEBS letters (24.11.1997)
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Journal Article
Target validation of cytochrome P450 CYP1B1 in prostate carcinoma with protein expression in associated hyperplastic and premalignant tissue
Carnell, Dawn M, Smith, Rowena E, Daley, Frances M, Barber, Paul R, Hoskin, Peter J, Wilson, George D, Murray, Graeme I, Everett, Steven A
Published in International journal of radiation oncology, biology, physics (01.02.2004)
Published in International journal of radiation oncology, biology, physics (01.02.2004)
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Journal Article
Conference Proceeding
Rates of reductive elimination of substituted nitrophenols from the (indol-3-yl)methyl position of indolequinones
Swann, E, Moody, CJ, Stratford, MRL, Patel, KB, Naylor, MA, Vojnovic, B, Wardman, P, Everett, SA
Published in Perkin 2 : an international journal of physical organic chemistry (01.01.2001)
Published in Perkin 2 : an international journal of physical organic chemistry (01.01.2001)
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Journal Article
2-Cyclopropylindoloquinones and Their Analogues as Bioreductively Activated Antitumor Agents: Structure−Activity in Vitro and Efficacy in Vivo
Naylor, Matthew A, Jaffar, Mohammed, Nolan, John, Stephens, Miriam A, Butler, Susan, Patel, Kantilal B, Everett, Steven A, Adams, Gerald E, Stratford, Ian J
Published in Journal of medicinal chemistry (18.07.1997)
Published in Journal of medicinal chemistry (18.07.1997)
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Journal Article
The role of nitric oxide in cancer improved methods for measurement of nitrite and nitrate by high-performance ion chromatography
Stratford, Michael R.L., Dennis, Madeleine F., Cochrane, Ralph, Parkins, Charles S., Everett, Steven A.
Published in Journal of Chromatography A (16.05.1997)
Published in Journal of Chromatography A (16.05.1997)
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Journal Article
Conference Proceeding
1-Methylindole-3-carboxaldehyde oxime derivatives
JANES, Robert W, POTTER, Brian S, NAYLOR, Matthew A, FERGUSON, Amanda C, PATEL, Kantilal B, STRATFORD, Michael R. L, WARDMAN, Peter, EVERETT, Steven A
Published in Acta crystallographica. Section C, Crystal structure communications (01.01.2001)
Published in Acta crystallographica. Section C, Crystal structure communications (01.01.2001)
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Journal Article
Radicals from one-electron reduction of nitro compounds, aromatic N-oxides and quinones: the kinetic basis for hypoxia-selective, bioreductive drugs
Wardman, P, Dennis, M F, Everett, S A, Patel, K B, Stratford, M R, Tracy, M
Published in Biochemical Society Symposia (01.01.1995)
Published in Biochemical Society Symposia (01.01.1995)
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Journal Article
Free-Radical Intermediates and Stable Products in the Oxidation of Indole-3-acetic acid
Candeias, Luis P, Folkes, Lisa K, Dennis, Madeleine F, Patel, Kantilal B, Everett, Steven A, Stratford, Michael R. L, Wardman, Peter
Published in Journal of physical chemistry (1952) (01.10.1994)
Published in Journal of physical chemistry (1952) (01.10.1994)
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Journal Article
Perthiyl radicals, trisulfide radical ions, and sulfate formation: a combined photolysis and radiolysis study on redox processes with organic di- and trisulfides
Everett, Steven A, Schoeneich, Christian, Stewart, John H, Asmus, Klaus Dieter
Published in Journal of physical chemistry (1952) (01.01.1992)
Published in Journal of physical chemistry (1952) (01.01.1992)
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Journal Article
Nitric oxide in biological fluids: analysis of nitrite and nitrate by high-performance ion chromatography
Everett, Steven A., Dennis, Madeleine F., Tozer, Gillian M., Prise, Vivien E., Wardman, Peter, Stratford, Michael R.L.
Published in Journal of Chromatography A (07.07.1995)
Published in Journal of Chromatography A (07.07.1995)
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Journal Article
Modifying rates of reductive elimination of leaving groups from indolequinone prodrugs: a key factor in controlling hypoxia-selective drug release
EVERETT, Steven A, SWANN, Elizabeth, NAYLOR, Matthew A, STRATFORD, Michael R. L, PATEL, Kantilal B, TIAN, Natasha, NEWMAN, Robert G, VOJNOVIC, Borivoj, MOODY, Christopher J, WARDMAN, Peter
Published in Biochemical pharmacology (2002)
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Published in Biochemical pharmacology (2002)
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