Muscarinic receptors stimulate AC2 by novel phosphorylation sites, whereas Gβγ subunits exert opposing effects depending on the G-protein source
Shen, Jia X, Wachten, Sebastian, Halls, Michelle L, Everett, Katy L, Cooper, Dermot M F
Published in Biochemical journal (01.11.2012)
Published in Biochemical journal (01.11.2012)
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Membrane Environment Exerts an Important Influence on Rac-Mediated Activation of Phospholipase Cγ2
Everett, Katy L., Buehler, Anja, Bunney, Tom D., Margineanu, Anca, Baxendale, Rhona W., Vatter, Petra, Retlich, Michael, Walliser, Claudia, Manning, Hugh B., Neil, Mark A. A., Dunsby, Christopher, French, Paul M. W., Gierschik, Peter, Katan, Matilda
Published in Molecular and Cellular Biology (01.03.2011)
Published in Molecular and Cellular Biology (01.03.2011)
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CD137/OX40 Bispecific Antibody Induces Potent Antitumor Activity that Is Dependent on Target Coengagement
Gaspar, Miguel, Pravin, John, Rodrigues, Leonor, Uhlenbroich, Sandra, Everett, Katy L, Wollerton, Francisca, Morrow, Michelle, Tuna, Mihriban, Brewis, Neil
Published in Cancer immunology research (01.06.2020)
Published in Cancer immunology research (01.06.2020)
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Generation of Fcabs targeting human and murine LAG-3 as building blocks for novel bispecific antibody therapeutics
Everett, Katy L., Kraman, Matthew, Wollerton, Francisca P.G., Zimarino, Carlo, Kmiecik, Katarzyna, Gaspar, Miguel, Pechouckova, Sarka, Allen, Natalie L., Doody, Jacqueline F., Tuna, Mihriban
Published in Methods (San Diego, Calif.) (01.02.2019)
Published in Methods (San Diego, Calif.) (01.02.2019)
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ADCY5 Couples Glucose to Insulin Secretion in Human Islets
HODSON, David J, MITCHELL, Ryan K, LAVALLARD, Vanessa, BOSCO, Domenico, PIEMONTI, Lorenzo, JOHNSON, Paul R, HUGHES, Stephen J, DALIANG LI, LI, Wen-Hong, SHAPIRO, A. M. James, RUTTER, Guy A, MARSELLI, Lorella, PULLEN, Timothy J, BRIAS, Silvia Gimeno, SEMPLICI, Francesca, EVERETT, Katy L, COOPER, Dermot M. F, BUGLIANI, Marco, MARCHETTI, Piero
Published in Diabetes (New York, N.Y.) (01.09.2014)
Published in Diabetes (New York, N.Y.) (01.09.2014)
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Direct binding between Orai1 and AC8 mediates dynamic interplay between Ca2+ and cAMP signaling
Willoughby, Debbie, Everett, Katy L, Halls, Michelle L, Pacheco, Jonathan, Skroblin, Philipp, Vaca, Luis, Klussmann, Enno, Cooper, Dermot M F
Published in Science signaling (10.04.2012)
Published in Science signaling (10.04.2012)
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A key phosphorylation site in AC8 mediates regulation of Ca(2+)-dependent cAMP dynamics by an AC8-AKAP79-PKA signalling complex
Willoughby, Debbie, Halls, Michelle L, Everett, Katy L, Ciruela, Antonio, Skroblin, Philipp, Klussmann, Enno, Cooper, Dermot M F
Published in Journal of cell science (01.12.2012)
Published in Journal of cell science (01.12.2012)
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AKAP79/150 Interacts with AC8 and Regulates Ca2+-dependent cAMP Synthesis in Pancreatic and Neuronal Systems
Willoughby, Debbie, Masada, Nanako, Wachten, Sebastian, Pagano, Mario, Halls, Michelle L., Everett, Katy L., Ciruela, Antonio, Cooper, Dermot M.F.
Published in The Journal of biological chemistry (25.06.2010)
Published in The Journal of biological chemistry (25.06.2010)
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A key phosphorylation site in AC8 mediates regulation of Ca2+-dependent cAMP dynamics by an AC8–AKAP79–PKA signalling complex
Willoughby, Debbie, Halls, Michelle L., Everett, Katy L., Ciruela, Antonio, Skroblin, Philipp, Klussmann, Enno, Cooper, Dermot M. F.
Published in Journal of cell science (01.12.2012)
Published in Journal of cell science (01.12.2012)
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Structural Insights into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2
Bunney, Tom D., Opaleye, Olaniyi, Roe, S. Mark, Vatter, Petra, Baxendale, Rhona W., Walliser, Claudia, Everett, Katy L., Josephs, Michelle B., Christow, Carolin, Rodrigues-Lima, Fernando, Gierschik, Peter, Pearl, Laurence H., Katan, Matilda
Published in Molecular cell (24.04.2009)
Published in Molecular cell (24.04.2009)
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Rac Regulates Its Effector Phospholipase Cγ2 through Interaction with a Split Pleckstrin Homology Domain
Walliser, Claudia, Retlich, Michael, Harris, Richard, Everett, Katy L., Josephs, Michelle B., Vatter, Petra, Esposito, Diego, Driscoll, Paul C., Katan, Matilda, Gierschik, Peter, Bunney, Tom D.
Published in The Journal of biological chemistry (31.10.2008)
Published in The Journal of biological chemistry (31.10.2008)
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Characterization of Phospholipase Cγ Enzymes with Gain-of-Function Mutations
Everett, Katy L., Bunney, Tom D., Yoon, Youngdae, Rodrigues-Lima, Fernando, Harris, Richard, Driscoll, Paul C., Abe, Koichiro, Fuchs, Helmut, Hrabé de Angelis, Martin, Yu, Philipp, Cho, Wohnwa, Katan, Matilda
Published in The Journal of biological chemistry (21.08.2009)
Published in The Journal of biological chemistry (21.08.2009)
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Journal Article
Membrane Environment Exerts an Important Influence on Rac-Mediated Activation of Phospholipase C gamma 2
Everett, Katy L, Buehler, Anja, Bunney, Tom D, Margineanu, Anca, Baxendale, Rhona W, Vatter, Petra, Retlich, Michael, Walliser, Claudia, Manning, Hugh B, Neil, Mark AA, Dunsby, Christopher, French, Paul MW, Gierschik, Peter, Katan, Matilda
Published in Molecular and cellular biology (15.03.2011)
Published in Molecular and cellular biology (15.03.2011)
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AKAP79/150 Interacts with AC8 and Regulates Ca2+-dependent cAMP Synthesis in Pancreatic and Neuronal Systems<inline-graphic xlink:href="sbox.jpg"/>
Willoughby, Debbie, Masada, Nanako, Wachten, Sebastian, Pagano, Mario, Halls, Michelle L, Everett, Katy L, Ciruela, Antonio, Cooper, Dermot MF
Published in The Journal of biological chemistry (21.04.2010)
Published in The Journal of biological chemistry (21.04.2010)
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Rac regulates its effector phospholipase Cγ2 through interaction with a split pleckstrin homology domain. VOLUME 283 (2008) PAGES 30351-30362
Walliser, Claudia, Retlich, Michael, Harris, Richard, Everett, Katy L., Josephs, Michelle B., Vatter, Petra, Esposito, Diego, Driscoll, Paul C., Katan, Matilda, Gierschik, Peter, Bunney, Tom D.
Published in The Journal of biological chemistry (27.03.2009)
Published in The Journal of biological chemistry (27.03.2009)
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rac regulates its effector phospholipase Cgamma2 through interaction with a split pleckstrin homology domain
Walliser, Claudia, Retlich, Michael, Harris, Richard, Everett, Katy L, Josephs, Michelle B, Vatter, Petra, Esposito, Diego, Driscoll, Paul C, Katan, Matilda, Gierschik, Peter, Bunney, Tom D
Published in The Journal of biological chemistry (31.10.2008)
Published in The Journal of biological chemistry (31.10.2008)
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Journal Article
Rac Regulates Its Effector Phospholipase Cγ2 through Interaction with a Split Pleckstrin Homology Domain
Claudia Walliser, Michael Retlich, Richard Harris, Katy L. Everett, Michelle B. Josephs, Petra Vatter, Diego Esposito, Paul C. Driscoll, Matilda Katan, Peter Gierschik, Tom D. Bunney
Published in The Journal of biological chemistry (31.10.2008)
Published in The Journal of biological chemistry (31.10.2008)
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Journal Article
Rac Regulates Its Effector Phospholipase Cγ2 through Interaction with a Split Pleckstrin Homology DomainS
Walliser, Claudia, Retlich, Michael, Harris, Richard, Everett, Katy L., Josephs, Michelle B., Vatter, Petra, Esposito, Diego, Driscoll, Paul C., Katan, Matilda, Gierschik, Peter, Bunney, Tom D.
Published in The Journal of biological chemistry (31.10.2008)
Published in The Journal of biological chemistry (31.10.2008)
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