The Potent Protein Kinase C-Selective Inhibitor AEB071 (Sotrastaurin) Represents a New Class of Immunosuppressive Agents Affecting Early T-Cell Activation
Evenou, Jean-Pierre, Wagner, Jürgen, Zenke, Gerhard, Brinkmann, Volker, Wagner, Kathrin, Kovarik, Jiri, Welzenbach, Karl A, Weitz-Schmidt, Gabriele, Guntermann, Christine, Towbin, Harry, Cottens, Sylvain, Kaminski, Sandra, Letschka, Thomas, Lutz-Nicoladoni, Christina, Gruber, Thomas, Hermann-Kleiter, Natascha, Thuille, Nikolaus, Baier, Gottfried
Published in The Journal of pharmacology and experimental therapeutics (01.09.2009)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2009)
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Journal Article
Discovery of 3-(1H-Indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione (AEB071), a Potent and Selective Inhibitor of Protein Kinase C Isotypes
Wagner, Jürgen, von Matt, Peter, Sedrani, Richard, Albert, Rainer, Cooke, Nigel, Ehrhardt, Claus, Geiser, Martin, Rummel, Gabriele, Stark, Wilhelm, Strauss, Andre, Cowan-Jacob, Sandra W, Beerli, Christian, Weckbecker, Gisbert, Evenou, Jean-Pierre, Zenke, Gerhard, Cottens, Sylvain
Published in Journal of medicinal chemistry (22.10.2009)
Published in Journal of medicinal chemistry (22.10.2009)
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Journal Article
A Streaming Distance Transform Algorithm for Neighborhood-Sequence Distances
Normand, Nicolas, Strand, Robin, Evenou, Pierre, Arlicot, Aurore
Published in Image processing on line (01.09.2014)
Published in Image processing on line (01.09.2014)
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Journal Article
Structure–Activity Relationship and Pharmacokinetic Studies of Sotrastaurin (AEB071), a Promising Novel Medicine for Prevention of Graft Rejection and Treatment of Psoriasis
Wagner, Jürgen, von Matt, Peter, Faller, Bernard, Cooke, Nigel G, Albert, Rainer, Sedrani, Richard, Wiegand, Hansjörg, Jean, Christian, Beerli, Christian, Weckbecker, Gisbert, Evenou, Jean-Pierre, Zenke, Gerhard, Cottens, Sylvain
Published in Journal of medicinal chemistry (08.09.2011)
Published in Journal of medicinal chemistry (08.09.2011)
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Journal Article
128-LB: Insulin Glargine 300 U/mL (Gla-300) vs. First-Generation Basal Insulins (BI) in Insulin-Naïve Type 2 Diabetes (T2D) Patients (Pts) With and Without Cardiovascular Disease (CVD): Outcomes of the Randomized Pragmatic Real-Life Clinical Trial ACHIEVE Control
FRIAS, JUAN P., EVENOU, PIERRE, DALTON, DAVID, DUNGAN, KATHLEEN M.
Published in Diabetes (New York, N.Y.) (01.06.2019)
Published in Diabetes (New York, N.Y.) (01.06.2019)
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Journal Article
Bridging beta-Cyclodextrin Prevents Self-Inclusion, Promotes Supra-molecular Polymerization, and Promotes Cooperative Interaction with Nucleic Acids
Evenou, Pierre, Rossignol, Julien, Pembouong, Gaelle, Gothland, Adelie, Colesnic, Dmitri, Barbeyron, Renaud, Rudiuk, Sergii, Marcelin, Anne-Genevieve, Menand, Mickael, Baigl, Damien, Calvez, Vincent, Bouteiller, Laurent, Sollogoub, Matthieu
Published in Angewandte Chemie International Edition (25.06.2018)
Published in Angewandte Chemie International Edition (25.06.2018)
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Journal Article
Bridging β‐Cyclodextrin Prevents Self‐Inclusion, Promotes Supramolecular Polymerization, and Promotes Cooperative Interaction with Nucleic Acids
Evenou, Pierre, Rossignol, Julien, Pembouong, Gaëlle, Gothland, Adélie, Colesnic, Dmitri, Barbeyron, Renaud, Rudiuk, Sergii, Marcelin, Anne‐Geneviève, Ménand, Mickaël, Baigl, Damien, Calvez, Vincent, Bouteiller, Laurent, Sollogoub, Matthieu
Published in Angewandte Chemie International Edition (25.06.2018)
Published in Angewandte Chemie International Edition (25.06.2018)
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Journal Article
1038-P: Insulin Glargine 300 U/ml (Gla-300) vs. First-Generation Standard-of-Care Basal Insulin Analogs (SOC-BI) in Insulin-Naïve Patients with Type 2 Diabetes (T2D): Impact of Renal Function on the Outcomes of the Randomized Pragmatic Real-Life Achieve Control S
MENEGHINI, LUIGI, CHENG, ALICE, EVENOU, PIERRE, GILL, JASVINDER, MOHAMED, AYAD, UMPIERREZ, GUILLERMO E.
Published in Diabetes (New York, N.Y.) (01.06.2020)
Published in Diabetes (New York, N.Y.) (01.06.2020)
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Journal Article
2,6-Naphthyridines as potent and selective inhibitors of the novel protein kinase C isozymes
van Eis, Maurice J., Evenou, Jean-Pierre, Floersheim, Philipp, Gaul, Christoph, Cowan-Jacob, Sandra W., Monovich, Lauren, Rummel, Gabriele, Schuler, Walter, Stark, Wilhelm, Strauss, Andre, Matt, Anette von, Vangrevelinghe, Eric, Wagner, Juergen, Soldermann, Nicolas
Published in Bioorganic & medicinal chemistry letters (15.12.2011)
Published in Bioorganic & medicinal chemistry letters (15.12.2011)
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Journal Article
Target attainment in insulin-naive patients at high risk for hypoglycemia: Results from ACHIEVE Control
Anderson, John, Meneghini, Luigi, Hinnen, Debbie, Gill, Jasvinder, Coudert, Mathieu, Evenou, Pierre, Munshi, Medha
Published in Journal of diabetes and its complications (01.04.2021)
Published in Journal of diabetes and its complications (01.04.2021)
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Journal Article
A Geometry Driven Reconstruction Algorithm for the Mojette Transform
Normand, Nicolas, Kingston, Andrew, Évenou, Pierre
Published in Discrete Geometry for Computer Imagery (01.01.2006)
Published in Discrete Geometry for Computer Imagery (01.01.2006)
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Book Chapter
Conference Proceeding
Abstract #322 Impact of Background Sulfonylurea Therapy on Attainment of A1C Targets Without Hypoglycemia in Insulin-Naïve Patients with Type 2 Diabetes Receiving Insulin Glargine 300u/Ml Vs other Basal Insulins in the Achieve Control Pragmatic Real-Life Study
Bailey, Timothy, Gill, Jasvinder, Evenou, Pierre, Berhanu, Paulos, Melas-Melt, Lydie, Strong, Jodi, Wright, Eugene
Published in Endocrine practice (01.04.2019)
Published in Endocrine practice (01.04.2019)
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Journal Article
IMPACT OF BACKGROUND SULFONYLUREA THERAPY ON ATTAINMENT OF A1C TARGETS WITHOUT HYPOGLYCEMIA IN INSULIN-NAIVE PATIENTS WITH TYPE 2 DIABETES RECEIVING INSULIN GLARGINE 300U/ML VS OTHER BASAL INSULINS IN THE ACHIEVE CONTROL PRAGMATIC REAL-LIFE STUDY
Bailey, Timothy, Gill, Jasvinder, Evenou, Pierre, Berhanu, Paulos, Melas-Melt, Lydie, Strong, Jodi, Wright, Eugene
Published in Endocrine practice (01.04.2019)
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Published in Endocrine practice (01.04.2019)
Journal Article
Minimal-delay distance transform for neighborhood-sequence distances in 2D and 3D
Normand, Nicolas, Strand, Robin, Evenou, Pierre, Arlicot, Aurore
Published in Computer vision and image understanding (01.04.2013)
Published in Computer vision and image understanding (01.04.2013)
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Journal Article
Post Hoc Analysis Evaluating the Impact of Antihyperglycemic Background Therapies on Attainment of A1C Targets Without Hypoglycemia in the ACHIEVE Control Pragmatic, Real-Life Study
Bailey, Timothy S, Evenou, Pierre, Gill, Jasvinder, Berhanu, Paulos, Raymond, Romain, Strong, Jodi, Wright, Jr, Eugene E
Published in Diabetes spectrum (01.11.2021)
Published in Diabetes spectrum (01.11.2021)
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Journal Article
Discovery of Novel (Imidazo[1,2-a]pyrazin-6-yl)ureas as Antiproliferative Agents Targeting P53 in Non-small Cell Lung Cancer Cell Lines
Bazin, Marc-Antoine, Rousseau, Bénédicte, Marhadour, Sophie, Tomasoni, Christophe, Evenou, Pierre, Piessard, Sylvie, Vaisberg, Abraham J, Ruchaud, Sandrine, Bach, Stéphane, Roussakis, Christos, Marchand, Pascal
Published in Anticancer research (01.04.2016)
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Published in Anticancer research (01.04.2016)
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