Novel non-nucleobase inhibitors of Staphylococcus aureus DNA polymerase IIIC
Rose, Yannick, Ciblat, Stéphane, Reddy, Ranga, Belley, Adam C., Dietrich, Evelyne, Lehoux, Dario, McKay, Geoffrey A., Poirier, Hugo, Far, Adel Rafai, Delorme, Daniel
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
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CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition
Gallo, David, Young, Jordan T. F., Fourtounis, Jimmy, Martino, Giovanni, Álvarez-Quilón, Alejandro, Bernier, Cynthia, Duffy, Nicole M., Papp, Robert, Roulston, Anne, Stocco, Rino, Szychowski, Janek, Veloso, Artur, Alam, Hunain, Baruah, Prasamit S., Fortin, Alexanne Bonneau, Bowlan, Julian, Chaudhary, Natasha, Desjardins, Jessica, Dietrich, Evelyne, Fournier, Sara, Fugère-Desjardins, Chloe, Goullet de Rugy, Theo, Leclaire, Marie-Eve, Liu, Bingcan, Bhaskaran, Vivek, Mamane, Yael, Melo, Henrique, Nicolas, Olivier, Singhania, Akul, Szilard, Rachel K., Tkáč, Ján, Yin, Shou Yun, Morris, Stephen J., Zinda, Michael, Marshall, C. Gary, Durocher, Daniel
Published in Nature (London) (28.04.2022)
Published in Nature (London) (28.04.2022)
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Discovery of an Orally Bioavailable and Selective PKMYT1 Inhibitor, RP-6306
Szychowski, Janek, Papp, Robert, Dietrich, Evelyne, Liu, Bingcan, Vallée, Frédéric, Leclaire, Marie-Eve, Fourtounis, Jimmy, Martino, Giovanni, Perryman, Alexander L., Pau, Victor, Yin, Shou Yun, Mader, Pavel, Roulston, Anne, Truchon, Jean-Francois, Marshall, C. Gary, Diallo, Mohamed, Duffy, Nicole M., Stocco, Rino, Godbout, Claude, Bonneau-Fortin, Alexanne, Kryczka, Rosie, Bhaskaran, Vivek, Mao, Daniel, Orlicky, Stephen, Beaulieu, Patrick, Turcotte, Pascal, Kurinov, Igor, Sicheri, Frank, Mamane, Yael, Gallant, Michel, Black, W. Cameron
Published in Journal of medicinal chemistry (11.08.2022)
Published in Journal of medicinal chemistry (11.08.2022)
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Oritavancin Exhibits Dual Mode of Action to Inhibit Cell-Wall Biosynthesis in Staphylococcus aureus
Kim, Sung Joon, Cegelski, Lynette, Stueber, Dirk, Singh, Manmilan, Dietrich, Evelyne, Tanaka, Kelly S.E., Parr, Thomas R., Far, Adel Rafai, Schaefer, Jacob
Published in Journal of molecular biology (14.03.2008)
Published in Journal of molecular biology (14.03.2008)
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Vancomycin and Oritavancin Have Different Modes of Action in Enterococcus faecium
Patti, Gary J., Kim, Sung Joon, Yu, Tsyr-Yan, Dietrich, Evelyne, Tanaka, Kelly S.E., Parr, Thomas R., Far, Adel Rafai, Schaefer, Jacob
Published in Journal of molecular biology (09.10.2009)
Published in Journal of molecular biology (09.10.2009)
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Linking Bisphosphonates to the Free Amino Groups in Fluoroquinolones: Preparation of Osteotropic Prodrugs for the Prevention of Osteomyelitis
Houghton, Tom J, Tanaka, Kelly S. E, Kang, Ting, Dietrich, Evelyne, Lafontaine, Yanick, Delorme, Daniel, Ferreira, Sandra S, Viens, Frederic, Arhin, Francis F, Sarmiento, Ingrid, Lehoux, Dario, Fadhil, Ibtihal, Laquerre, Karine, Liu, Jing, Ostiguy, Valérie, Poirier, Hugo, Moeck, Gregory, Parr, Thomas R, Far, Adel Rafai
Published in Journal of medicinal chemistry (13.11.2008)
Published in Journal of medicinal chemistry (13.11.2008)
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Synthesis and evaluation of NS5A inhibitors containing diverse heteroaromatic cores
Henderson, James A., Bilimoria, Darius, Bubenik, Monica, Cadilhac, Caroline, Cottrell, Kevin M., Denis, Francois, Dietrich, Evelyne, Ewing, Nigel, Falardeau, Guy, Giroux, Simon, L’Heureux, Lucille, Liu, Bingcan, Mani, Nagraj, Morris, Mark, Nicolas, Olivier, Pereira, Oswy Z., Poisson, Carl, Reddy, T. Jagadeeswar, Selliah, Subajini, Shawgo, Rebecca S., Vaillancourt, Louis, Wang, Jian, Xu, Jinwang, Chauret, Nathalie, Berlioz-Seux, Francoise, Chan, Laval C., Das, Sanjoy K., Grillot, Anne-Laure, Bennani, Youssef L., Maxwell, John P.
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
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Discovery of thienoimidazole-based HCV NS5A inhibitors. Part 1: C-2-Symmetric inhibitors with diyne and biphenyl linkers
Giroux, Simon, Bilimoria, Darius, Cadilhac, Caroline, Cottrell, Kevin M., Denis, Francois, Dietrich, Evelyne, Ewing, Nigel, Henderson, James A., L'Heureux, Lucille, Mani, Nagraj, Morris, Mark, Nicolas, Olivier, Reddy, T. Jagadeeswar, Selliah, Subajini, Shawgo, Rebecca S., Xu, Jinwang, Chauret, Nathalie, Berlioz-Seux, Francoise, Chan, Laval C., Das, Sanjoy K., Grillot, Anne-Laure, Bennani, Youssef L., Maxwell, John P.
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
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Benzimidazole-containing HCV NS5A inhibitors: Effect of 4-substituted pyrrolidines in balancing genotype 1a and 1b potency
Henderson, James A., Bilimoria, Darius, Bubenik, Monica, Cadilhac, Caroline, Cottrell, Kevin M., Dietrich, Evelyne, Denis, Francois, Ewing, Nigel, Falardeau, Guy, Giroux, Simon, Grey, Ronald, L’Heureux, Lucille, Liu, Bingcan, Mani, Nagraj, Morris, Mark, Nicolas, Olivier, Pereira, Oswy Z., Poisson, Carl, Govinda Rao, B., Reddy, T. Jagadeeswar, Selliah, Subajini, Shawgo, Rebecca S., Vaillancourt, Louis, Wang, Jian, Yannopoulos, Constantin G., Chauret, Nathalie, Berlioz-Seux, Francoise, Chan, Laval C., Das, Sanjoy K., Grillot, Anne-Laure, Bennani, Youssef L., Maxwell, John P.
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
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Discovery of thienoimidazole-based HCV NS5A inhibitors. Part 1: C sub(2)-Symmetric inhibitors with diyne and biphenyl linkers
Giroux, Simon, Bilimoria, Darius, Cadilhac, Caroline, Cottrell, Kevin M, Denis, Francois, Dietrich, Evelyne, Ewing, Nigel, Henderson, James A, L'Heureux, Lucille, Mani, Nagraj, Morris, Mark, Nicolas, Olivier, Reddy, TJagadeeswar, Selliah, Subajini, Shawgo, Rebecca S, Xu, Jinwang, Chauret, Nathalie, Berlioz-Seux, Francoise, Chan, Laval C, Das, Sanjoy K, Grillot, Anne-Laure, Bennani, Youssef L, Maxwell, John P
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
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Discovery of thienoimidazole-based HCV NS5A inhibitors. Part 1: C2-Symmetric inhibitors with diyne and biphenyl linkers
Giroux, Simon, Bilimoria, Darius, Cadilhac, Caroline, Cottrell, Kevin M., Denis, Francois, Dietrich, Evelyne, Ewing, Nigel, Henderson, James A., L’Heureux, Lucille, Mani, Nagraj, Morris, Mark, Nicolas, Olivier, Reddy, T. Jagadeeswar, Selliah, Subajini, Shawgo, Rebecca S., Xu, Jinwang, Chauret, Nathalie, Berlioz-Seux, Francoise, Chan, Laval C., Das, Sanjoy K., Grillot, Anne-Laure, Bennani, Youssef L., Maxwell, John P.
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
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Discovery of thienoimidazole-based HCV NS5A inhibitors. Part 2: Non-symmetric inhibitors with potent activity against genotype 1a and 1b
Giroux, Simon, Bilimoria, Darius, Cadilhac, Caroline, Cottrell, Kevin M., Denis, Francois, Dietrich, Evelyne, Ewing, Nigel, Henderson, James A., L’Heureux, Lucille, Mani, Nagraj, Morris, Mark, Nicolas, Olivier, Reddy, T. Jagadeeswar, Selliah, Subajini, Shawgo, Rebecca S., Xu, Jinwang, Chauret, Nathalie, Berlioz-Seux, Francoise, Chan, Laval C., Das, Sanjoy K., Grillot, Anne-Laure, Bennani, Youssef L., Maxwell, John P.
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
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Synthesis and in vitro evaluation of bisphosphonated glycopeptide prodrugs for the treatment of osteomyelitis
Tanaka, Kelly S.E., Dietrich, Evelyne, Ciblat, Stéphane, Métayer, Claude, Arhin, Francis F., Sarmiento, Ingrid, Moeck, Gregory, Parr, Thomas R., Far, Adel Rafai
Published in Bioorganic & medicinal chemistry letters (15.02.2010)
Published in Bioorganic & medicinal chemistry letters (15.02.2010)
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Bisphosphonated fluoroquinolone esters as osteotropic prodrugs for the prevention of osteomyelitis
Tanaka, Kelly S.E., Houghton, Tom J., Kang, Ting, Dietrich, Evelyne, Delorme, Daniel, Ferreira, Sandra S., Caron, Laurence, Viens, Frederic, Arhin, Francis F., Sarmiento, Ingrid, Lehoux, Dario, Fadhil, Ibtihal, Laquerre, Karine, Liu, Jing, Ostiguy, Valérie, Poirier, Hugo, Moeck, Gregory, Parr, Thomas R., Rafai Far, Adel
Published in Bioorganic & medicinal chemistry (15.10.2008)
Published in Bioorganic & medicinal chemistry (15.10.2008)
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A new class of small molecule RNA polymerase inhibitors with activity against Rifampicin-resistant Staphylococcus aureus
ARHIN, Francis, BELANGER, Odette, MCKAY, Geoffrey A, MOECK, Greg, REDDY, Ranga, ROSE, Yannick, SRIKUMAR, Ramakrishnan, TANAKA, Kelly S. E, WILLIAMS, Daniel M, GROS, Philippe, PELLETIER, Jerry, PARR, Thomas R, CIBLAT, Stéphane, FAR, Adel Rafai, DEHBI, Mohammed, DELORME, Daniel, DIETRICH, Evelyne, DIXIT, Dilip, LAFONTAINE, Yanick, LEHOUX, Dario, JING LIU
Published in Bioorganic & medicinal chemistry (01.09.2006)
Published in Bioorganic & medicinal chemistry (01.09.2006)
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Bisphosphonated Benzoxazinorifamycin Prodrugs for the Prevention and Treatment of Osteomyelitis
Reddy, Ranga, Dietrich, Evelyne, Lafontaine, Yanick, Houghton, Tom J., Belanger, Odette, Dubois, Anik, Arhin, Francis F., Sarmiento, Ingrid, Fadhil, Ibtihal, Laquerre, Karine, Ostiguy, Valerie, Lehoux, Dario, Moeck, Gregory, Parr Jr, Thomas R., Rafai Far, Adel
Published in ChemMedChem (15.12.2008)
Published in ChemMedChem (15.12.2008)
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Mannose derivatives for treating bacterial infections
Gallant, Michel, Vallee, Frederic, Dietrich, Evelyne, Vaillancourt, Louis, Truchon, Jean-Francois, Reddy, Thumkunta
Year of Publication 27.10.2023
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Year of Publication 27.10.2023
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