Novel Immunomodulatory Proteins Generated via Directed Evolution of Variant IgSF Domains
Levin, Steven D, Evans, Lawrence S, Bort, Susan, Rickel, Erika, Lewis, Katherine E, Wu, Rebecca P, Hoover, Joseph, MacNeil, Sean, La, David, Wolfson, Martin F, Rixon, Mark W, Dillon, Stacey R, Kornacker, Michael G, Swanson, Ryan, Peng, Stanford L
Published in Frontiers in immunology (21.01.2020)
Published in Frontiers in immunology (21.01.2020)
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Journal Article
Povetacicept, an Enhanced Dual APRIL/BAFF Antagonist That Modulates B Lymphocytes and Pathogenic Autoantibodies for the Treatment of Lupus and Other B Cell–Related Autoimmune Diseases
Evans, Lawrence S., Lewis, Katherine E., DeMonte, Daniel, Bhandari, Janhavi G., Garrett, Logan B., Kuijper, Joseph L., Ardourel, Daniel, Wolfson, Martin F., Debrot, Susan, Mudri, Sherri, Kleist, Kayla, Griffin, Luana L., Hebb, LuAnne, Sanderson, Russell J., Wang, NingXin, Seaberg, Michelle, Chunyk, Allison G., Yang, Jing, Hong, Youji, Maria, Zahra, Messenheimer, David J., Holland, Pamela M., Peng, Stanford L., Rixon, Mark W., Dillon, Stacey R.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.07.2023)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.07.2023)
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Journal Article
Non‐Redundant Roles of T Cell Costimulation Pathways in Inflammatory Arthritis Revealed by Dual Blockade of ICOS and CD28 with Acazicolcept (ALPN‐101)
Dillon, Stacey R., Evans, Lawrence S., Lewis, Katherine E., Debrot, Susan, Blair, Tiffany C., Mudri, Sherri, Kleist, Kayla, Levin, Steven D., Bhandari, Janhavi G., Garrett, Logan, Wolfson, Martin F., Holland, Pamela M., Rixon, Mark W., Peng, Stanford L.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.08.2023)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.08.2023)
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Journal Article
Systemic Administration of Acazicolcept, a Dual CD28 and Inducible T cell Costimulator Inhibitor, Ameliorates Experimental Autoimmune Uveitis
Wilson, Leslie, Lewis, Katherine E, Evans, Lawrence S, Dillon, Stacey R, Pepple, Kathryn L
Published in Translational vision science & technology (01.03.2023)
Published in Translational vision science & technology (01.03.2023)
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Journal Article
P104 Upregulation of both APRIL and BAFF in systemic lupus erythematosus suggests non-redundant roles, further revealed by potent dual inhibition with povetacicept (TACI vTD-Fc; ALPN-303)
Lewis, Katherine E, Maria, Zahra, Repash, Elizabeth, Blair, Tiffany C, Enstrom, Amanda, Evans, Lawrence S, Bankhead, Armand, Simsek, Ismail, Peng, Stanford L, Dillon, Stacey R
Published in Lupus science & medicine (14.03.2024)
Published in Lupus science & medicine (14.03.2024)
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Journal Article
Mo1093 ALPN-101, A FIRST-IN-CLASS DUAL ICOS/CD28 ANTAGONIST, DEMONSTRATES EFFICACY IN PATIENT-DERIVED PBMC IN VITRO AND IN AN IN VIVO T CELL TRANSFER MODEL OF CHRONIC INFLAMMATORY BOWEL DISEASE (IBD)
Dillon, Stacey R., Evans, Lawrence S., Bort, Susan, Mudri, Sherri, Lewis, Katherine, Rixon, Mark, Bhandari, Janhavi, Peng, Stanford, Swiderek, Kristine M.
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2020)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2020)
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Journal Article
Novel Variant Ig Domain (vIgD) Proteins Generated Via Directed Evolution of Igsf Domains Have Therapeutic Efficacy in Animal Models of Graft Versus Host Disease
Levin, Steven D, Evans, Lawrence S., Rickel, Erika, Wolfson, Martin F., Dillon, Stacey R., Kornacker, Michael G., Swanson, Ryan, Peng, Stanford L.
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Journal Article
Therapeutic Candidate Alpn-101, a Dual ICOS/CD28 Antagonist, Potently Suppresses Human/NSG Mouse Xenograft Graft Vs. Host Disease (GvHD) in a Dose Ranging Study and Reduces Disease Activity in a Mouse Model of Hemophagocytic Lymphohistiocytosis (HLH)
Dillon, Stacey R., Lewis, Katherine E., Verbist, Katherine, Tedrick, Paige, Albeituni, Sabrin, Swanson, Ryan, Evans, Lawrence S., Levin, Steven D, Rixon, Mark W., Peng, Stanford L., Nichols, Kim E., Swiderek, Kristine M.
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Journal Article
Novel immunomodulatory proteins generated via directed evolution of variant IgSF domains
Evans, Lawrence S, Levin, Steven D, Rickel, Erika, Wolfson, Martin F, Dillon, Stacey R, Kornacker, Michael G, Swanson, Ryan, Peng, Stanford L
Published in The Journal of immunology (1950) (01.05.2017)
Published in The Journal of immunology (1950) (01.05.2017)
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Journal Article
Alpn-101, a Dual ICOS/CD28 Antagonist, Demonstrates Potent and Dose-Dependent Suppression of Graft Vs. Host Disease (GvHD) in a Human/NSG Mouse Xenograft Model, with Activity Superior to CD28 or ICOS Single Pathway Antagonists
Dillon, Stacey R., Yang, Jing, Lewis, Katherine E., Evans, Lawrence S., Mudri, Sherri, Wu, Rebecca, Swiderek, Kristine M., Peng, Stanford L.
Published in Biology of blood and marrow transplantation (01.03.2019)
Published in Biology of blood and marrow transplantation (01.03.2019)
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Journal Article
244 - A Dual ICOS/CD28 Antagonist ICOSL Variant Ig Domain (vIgD) Potently Suppresses Human Mixed Lymphocyte Reactions and Human/NSG Mouse Xenograft Graft vs. Host Disease (GvHD)
Dillon, Stacey R., Lewis, Katherine E., Swanson, Ryan, Evans, Lawrence S., Kornacker, Michael G., Levin, Steven D., Wolfson, Martin F., Rickel, Erika, Bort, Susan J., Moss, Aaron M., Seaberg, Michelle A., Bhandari, Janhavi, MacNeil, Sean, Hoover, Joe, Rixon, Mark W., Peng, Stanford L.
Published in Biology of blood and marrow transplantation (01.03.2018)
Published in Biology of blood and marrow transplantation (01.03.2018)
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Journal Article
A Dual ICOS/CD28 Antagonist ICOSL Variant Ig Domain (vIgD) Potently Suppresses Human Mixed Lymphocyte Reactions and Human/NSG Mouse Xenograft Graft vs. Host Disease (GvHD)
Dillon, Stacey R., Lewis, Katherine E., Swanson, Ryan, Evans, Lawrence S., Kornacker, Michael G., Levin, Steven D., Wolfson, Martin F., Rickel, Erika, Bort, Susan J., Moss, Aaron M., Seaberg, Michelle A., Bhandari, Janhavi, MacNeil, Sean, Hoover, Joe, Rixon, Mark W., Peng, Stanford L.
Published in Biology of blood and marrow transplantation (01.03.2018)
Published in Biology of blood and marrow transplantation (01.03.2018)
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Journal Article
Tuberculosis after jejunoileal bypass for obesity
Pickleman, J R, Evans, L S, Kane, J M, Freeark, R J
Published in JAMA : the journal of the American Medical Association (17.11.1975)
Published in JAMA : the journal of the American Medical Association (17.11.1975)
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Journal Article
Oculomotor Nuclear Complex Infarction: Clinical and Radiological Correlation
Biller, José, Shapiro, Rita, Evans, Lawrence S, Haag, Jeffrey R, Fine, Michael
Published in Archives of neurology (Chicago) (01.09.1984)
Published in Archives of neurology (Chicago) (01.09.1984)
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Journal Article
Expression of chimeric granulocyte-macrophage colony-stimulating factor/interleukin 2 receptors in human cytotoxic T lymphocyte clones results in granulocyte-macrophage colony-stimulating factor-dependent growth
Evans, L S, Witte, P R, Feldhaus, A L, Nelson, B H, Riddell, S R, Greenberg, P D, Lupton, S D, Jones, L A
Published in Human gene therapy (10.08.1999)
Published in Human gene therapy (10.08.1999)
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Journal Article
Calibration error in dark adaptometer
Maggiano, J M, Fishman, G A, Evans, L S, Sieving, P, Goldbaum, M
Published in Archives of ophthalmology (1960) (01.06.1978)
Published in Archives of ophthalmology (1960) (01.06.1978)
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Journal Article
Diagnosis and treatment of retrobulbar hemorrhage
Bailey, Warren K., Kuo, Paul C., Evans, Lawrence S.
Published in Journal of oral and maxillofacial surgery (01.07.1993)
Published in Journal of oral and maxillofacial surgery (01.07.1993)
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Journal Article