Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors
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Published in Nature (London) (26.07.2012)
Published in Nature (London) (26.07.2012)
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AXL inhibition sensitizes mesenchymal cancer cells to antimitotic drugs
Wilson, Catherine, Ye, Xiaofen, Pham, Thinh, Lin, Eva, Chan, Sara, McNamara, Erin, Neve, Richard M, Belmont, Lisa, Koeppen, Hartmut, Yauch, Robert L, Ashkenazi, Avi, Settleman, Jeff
Published in Cancer research (Chicago, Ill.) (15.10.2014)
Published in Cancer research (Chicago, Ill.) (15.10.2014)
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Selective PROTAC-mediated degradation of SMARCA2 is efficacious in SMARCA4 mutant cancers
Cantley, Jennifer, Ye, Xiaofen, Rousseau, Emma, Januario, Tom, Hamman, Brian D., Rose, Christopher M., Cheung, Tommy K., Hinkle, Trent, Soto, Leofal, Quinn, Connor, Harbin, Alicia, Bortolon, Elizabeth, Chen, Xin, Haskell, Roy, Lin, Eva, Yu, Shang-Fan, Del Rosario, Geoff, Chan, Emily, Dunlap, Debra, Koeppen, Hartmut, Martin, Scott, Merchant, Mark, Grimmer, Matt, Broccatelli, Fabio, Wang, Jing, Pizzano, Jennifer, Dragovich, Peter S., Berlin, Michael, Yauch, Robert L.
Published in Nature communications (10.11.2022)
Published in Nature communications (10.11.2022)
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Exon array profiling detects EML4-ALK fusion in breast, colorectal, and non-small cell lung cancers
Lin, Eva, Li, Li, Guan, Yinghui, Soriano, Robert, Rivers, Celina Sanchez, Mohan, Sankar, Pandita, Ajay, Tang, Jerry, Modrusan, Zora
Published in Molecular cancer research (01.09.2009)
Published in Molecular cancer research (01.09.2009)
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Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors
Merchant, Mark, Moffat, John, Schaefer, Gabriele, Chan, Jocelyn, Wang, Xi, Orr, Christine, Cheng, Jason, Hunsaker, Thomas, Shao, Lily, Wang, Stephanie J, Wagle, Marie-Claire, Lin, Eva, Haverty, Peter M, Shahidi-Latham, Sheerin, Ngu, Hai, Solon, Margaret, Eastham-Anderson, Jeffrey, Koeppen, Hartmut, Huang, Shih-Min A, Schwarz, Jacob, Belvin, Marcia, Kirouac, Daniel, Junttila, Melissa R
Published in PloS one (05.10.2017)
Published in PloS one (05.10.2017)
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Evaluation of statistical approaches for association testing in noisy drug screening data
Smirnov, Petr, Smith, Ian, Safikhani, Zhaleh, Ba-Alawi, Wail, Khodakarami, Farnoosh, Lin, Eva, Yu, Yihong, Martin, Scott, Ortmann, Janosch, Aittokallio, Tero, Hafner, Marc, Haibe-Kains, Benjamin
Published in BMC bioinformatics (18.05.2022)
Published in BMC bioinformatics (18.05.2022)
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Distinct resistance mechanisms arise to allosteric vs. ATP-competitive AKT inhibitors
Savill, Kristin M. Zimmerman, Lee, Brian B., Oeh, Jason, Lin, Jie, Lin, Eva, Chung, Wei-Jen, Young, Amy, Chen, Wennie, Miś, Monika, Mesh, Kathryn, Eastham, Jeffrey, Gnad, Florian, Jiang, Zhaoshi, Stawiski, Eric W., Haley, Benjamin, Daemen, Anneleen, Wang, Xiaojing, Koeppen, Hartmut, Modrusan, Zora, Martin, Scott E., Sampath, Deepak, Lin, Kui
Published in Nature communications (19.04.2022)
Published in Nature communications (19.04.2022)
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Orchestrating and sharing large multimodal data for transparent and reproducible research
Mammoliti, Anthony, Smirnov, Petr, Nakano, Minoru, Safikhani, Zhaleh, Eeles, Christopher, Seo, Heewon, Nair, Sisira Kadambat, Mer, Arvind S., Smith, Ian, Ho, Chantal, Beri, Gangesh, Kusko, Rebecca, Lin, Eva, Yu, Yihong, Martin, Scott, Hafner, Marc, Haibe-Kains, Benjamin
Published in Nature communications (04.10.2021)
Published in Nature communications (04.10.2021)
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Synthesis and anti-cancer activity of benzothiazole containing phthalimide on human carcinoma cell lines
Kok, Stanton Hon Lung, Gambari, Roberto, Chui, Chung Hin, Yuen, Marcus Chun Wah, Lin, Eva, Wong, Raymond Siu Ming, Lau, Fung Yi, Cheng, Gregory Yin Ming, Lam, Wing Sze, Chan, Sau Hing, Lam, Kim Hung, Cheng, Chor Hing, Lai, Paul Bo Shan, Yu, Michael Wing Yiu, Cheung, Filly, Tang, Johnny Cheuk On, Chan, Albert Sun Chi
Published in Bioorganic & medicinal chemistry (01.04.2008)
Published in Bioorganic & medicinal chemistry (01.04.2008)
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Correction: Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors
Merchant, Mark, Moffat, John, Schaefer, Gabriele, Chan, Jocelyn, Wang, Xi, Orr, Christine, Cheng, Jason, Hunsaker, Thomas, Shao, Lily, Wang, Stephanie J, Wagle, Marie-Claire, Lin, Eva, Haverty, Peter M, Shahidi-Latham, Sheerin, Ngu, Hai, Solon, Margaret, Eastham-Anderson, Jeffrey, Koeppen, Hartmut, Huang, Shih-Min A, Schwarz, Jacob, Belvin, Marcia, Kirouac, Daniel, Junttila, Melissa R
Published in PloS one (2018)
Published in PloS one (2018)
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Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines
Mygland, Line, Brinch, Shoshy Alam, Strand, Martin Frank, Olsen, Petter Angell, Aizenshtadt, Aleksandra, Lund, Kaja, Solberg, Nina Therese, Lycke, Max, Thorvaldsen, Tor Espen, Espada, Sandra, Misaghian, Dorna, Page, Christian M., Agafonov, Oleg, Nygård, Ståle, Chi, Nai-Wen, Lin, Eva, Tan, Jenille, Yu, Yihong, Costa, Mike, Krauss, Stefan, Waaler, Jo
Published in iScience (23.07.2021)
Published in iScience (23.07.2021)
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Oncogenic Activating Mutations Are Associated with Local Copy Gain
Modrek, Barmak, Ge, Lin, Pandita, Ajay, Lin, Eva, Mohan, Sankar, Yue, Peng, Guerrero, Steve, Lin, William M, Pham, Thinh, Modrusan, Zora, Seshagiri, Somasekar, Stern, Howard M, Waring, Paul, Garraway, Levi A, Chant, John, Stokoe, David, Cavet, Guy
Published in Molecular cancer research (01.08.2009)
Published in Molecular cancer research (01.08.2009)
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Rapid activation of ERK by 6-hydroxydopamine promotes survival of dopaminergic cells
Lin, Eva, Cavanaugh, Jane E., Leak, Rehana K., Perez, Ruth G., Zigmond, Michael J.
Published in Journal of neuroscience research (01.01.2008)
Published in Journal of neuroscience research (01.01.2008)
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Regulation of the 75-kDa Subunit of Mitochondrial Complex I by Iron
Lin, Eva, Graziano, Joseph H., Freyer, Greg A.
Published in The Journal of biological chemistry (20.07.2001)
Published in The Journal of biological chemistry (20.07.2001)
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Reproducible pharmacogenomic profiling of cancer cell line panels
Haverty, Peter M., Lin, Eva, Tan, Jenille, Yu, Yihong, Lam, Billy, Lianoglou, Steve, Neve, Richard M., Martin, Scott, Settleman, Jeff, Yauch, Robert L., Bourgon, Richard
Published in Nature (London) (19.05.2016)
Published in Nature (London) (19.05.2016)
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USP7 small-molecule inhibitors interfere with ubiquitin binding
Kategaya, Lorna, Di Lello, Paola, Rougé, Lionel, Pastor, Richard, Clark, Kevin R., Drummond, Jason, Kleinheinz, Tracy, Lin, Eva, Upton, John-Paul, Prakash, Sumit, Heideker, Johanna, McCleland, Mark, Ritorto, Maria Stella, Alessi, Dario R., Trost, Matthias, Bainbridge, Travis W., Kwok, Michael C. M., Ma, Taylur P., Stiffler, Zachary, Brasher, Bradley, Tang, Yinyan, Jaishankar, Priyadarshini, Hearn, Brian R., Renslo, Adam R., Arkin, Michelle R., Cohen, Frederick, Yu, Kebing, Peale, Frank, Gnad, Florian, Chang, Matthew T., Klijn, Christiaan, Blackwood, Elizabeth, Martin, Scott E., Forrest, William F., Ernst, James A., Ndubaku, Chudi, Wang, Xiaojing, Beresini, Maureen H., Tsui, Vickie, Schwerdtfeger, Carsten, Blake, Robert A., Murray, Jeremy, Maurer, Till, Wertz, Ingrid E.
Published in Nature (London) (26.10.2017)
Published in Nature (London) (26.10.2017)
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