Novel anti-4-1BB×PD-L1 bispecific antibody augments anti-tumor immunity through tumor-directed T-cell activation and checkpoint blockade
Jeong, Seongju, Park, Eunyoung, Kim, Hyung-Don, Sung, Eunsil, Kim, Hyunjoo, Jeon, Jaehyoung, Kim, Youngkwang, Jung, Ui-jung, Son, Yong-Gyu, Hong, Youngeun, Lee, Hanbyul, Lee, Shinai, Lim, Yangmi, Won, Jonghwa, Jeon, Minwoo, Hwang, Shin, Fang, Lei, Jiang, Wenqing, Wang, Zhengyi, Shin, Eui-Cheol, Park, Su-Hyung, Jung, Jaeho
Published in Journal for immunotherapy of cancer (01.07.2021)
Published in Journal for immunotherapy of cancer (01.07.2021)
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Journal Article
CLDN18.2 and 4-1BB bispecific antibody givastomig exerts antitumor activity through CLDN18.2-expressing tumor-directed T-cell activation
Gao, Jing, Wang, Zhengyi, Jiang, Wenqing, Zhang, Yanni, Meng, Zhen, Niu, Yanling, Sheng, Zhen, Chen, Chan, Liu, Xuejun, Chen, Xi, Liu, Chanjuan, Jia, Keren, Zhang, Cheng, Liao, Haiyan, Jung, Jaeho, Sung, Eunsil, Chung, Hyejin, Zhang, Jingwu Z., Zhu, Andrew X., Shen, Lin
Published in Journal for immunotherapy of cancer (01.06.2023)
Published in Journal for immunotherapy of cancer (01.06.2023)
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Journal Article
892 ABL503 (TJ-L14B), PD-L1x4–1BB bispecific antibody induces superior anti-tumor activity by PD-L1-dependent 4–1BB activation with the increase of 4–1BB+CD8+ T cells in tumor microenvironment
Jung, Uijung, Jeon, Jaehyoung, Lee, Shinai, Jin, Hyung-Seung, Kim, Youngkwang, Sung, Eunsil, Kim, Hyunjoo, Lim, Yangmi, Won, Jonghwa, Wang, Zhengyi, Jiang, Wenqing, Jung, Jaeho, You, Gihoon
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
Abstract 5644: Claudin 18.2 X 4-1BB bispecific antibody induced potent tumor inhibition through tumor-specific 4-1BB activation
Jiang, Wenqing, Fang, Lei, Wang, Zhengyi, Guo, Taylor B., Park, Eunyoung, Sung, Eunsil, Jung, Jaeho
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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LAG-3xPD-L1 bispecific antibody potentiates antitumor responses of T cells through dendritic cell activation
Sung, Eunsil, Ko, Minkyung, Won, Ju-young, Jo, Yunju, Park, Eunyoung, Kim, Hyunjoo, Choi, Eunji, Jung, Ui-jung, Jeon, Jaehyoung, Kim, Youngkwang, Ahn, Hyejin, Choi, Da-som, Choi, Seunghyun, Hong, Youngeun, Park, Hyeyoung, Lee, Hanbyul, Son, Yong-Gyu, Park, Kyeongsu, Won, Jonghwa, Oh, Soo Jin, Lee, Seonmin, Kim, Kyu-pyo, Yoo, Changhoon, Song, Hyun Kyu, Jin, Hyung-seung, Jung, Jaeho, Park, Yoon
Published in Molecular therapy (03.08.2022)
Published in Molecular therapy (03.08.2022)
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Abstract 1633: ABL501, PD-L1 x LAG-3, a bispecific antibody promotes enhanced human T cell activation through targeting simultaneously two immune checkpoint inhibitors, LAG-3 and PD-L1
Park, Eunyoung, Kim, Hyunejoo, Sung, Eunsil, Jung, Uijung, Hong, Youngeun, Lee, Hanbyul, Ko, Minkyung, Park, Yoon, Park, Chan Kwon, Kim, Seung Joon, Yoo, Jongman, Lee, Kyung Jin, Kim, Jihyo, Lee, Bo Eun, Won, Jonghwa, Jung, Jaeho
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Grabody B, an IGF1 receptor-based shuttle, mediates efficient delivery of biologics across the blood-brain barrier
Shin, Jung-Won, An, Sungwon, Kim, Dongin, Kim, Hyunjoo, Ahn, Jinhyung, Eom, Jaehyun, You, Weon-Kyoo, Yun, Hyesu, Lee, Bora, Sung, Byungje, Jung, Jinwon, Kim, Sehyun, Son, Yonggyu, Sung, Eunsil, Lee, Hanbyul, Lee, Suyeon, Song, Daehae, Pak, Youngdon, Sandhu, Jagdeep K., Haqqani, Arsalan S., Stanimirovic, Danica B., Yoo, Jiseon, Kim, Donghwan, Maeng, Sungho, Lee, Jeonghun, Lee, Sang Hoon
Published in Cell reports methods (21.11.2022)
Published in Cell reports methods (21.11.2022)
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Abstract 6296: Preclinical study of a novel anti-CLEC12A antibody-drug conjugate with a glucuronide-protected pyrrolobenzodiazepine payload
Jung, Jinwon, Kim, Juhee, Lee, Bora, Kwon, Jung A, Lee, Suyoun, Yoo, Byeongmin, Ko, Minji, Ryu, Ilhwan, Yeom, Donghoon, Lee, Kyoungjae, Eom, Jaehyun, Lee, Hanbyul, Ahn, Jinhyung, Sung, Eunsil, You, Weonkyoo, Lee, Sang Hoon, Kim, Myeong Joo, Kwon, Keon Woo, Bae, Hyun Joo, Park, Yun-Hee, Song, Ho Young, Chung, Chul-Woong
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Anti-claudin 18.2 and anti-4-1BB bispecific antibodies and uses thereof
GUO, Bingshi, PARK, Eunyoung, SUNG, Byungje, FANG, Lei, SUNG, Eunsil, JIANG, Wenqing, WANG, Zhengyi
Year of Publication 01.08.2024
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Year of Publication 01.08.2024
Patent
ANTI-CLAUDIN 18.2 AND ANTI-4-1BB BISPECIFIC ANTIBODIES AND USES THEREOF
Park, Eunyoung, Sung, Eunsil, Wang, Zhengyi, Fang, Lei, Jiang, Wenqing, Sung, Byungje, Guo, Bingshi
Year of Publication 03.11.2022
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Year of Publication 03.11.2022
Patent
ANTI-PD-L1/ANTI-B7-H3 MULTISPECIFIC ANTIBODIES AND USES THEREOF
Park, Eunyoung, Sung, Eunsil, Jeong, Junhyun, Fang, Lei, Jeon, Jaehyoung, Song, Daehae, Jiang, Wenqing, Cui, Feifei, Lee, Sunju
Year of Publication 22.06.2023
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Year of Publication 22.06.2023
Patent
ANTI-PD-L1/ANTI-B7-H3 MULTISPECIFIC ANTIBODIES AND USES THEREOF
LEE, Sunju, PARK, Eunyoung, CUI, Feifei, SONG, Daehae, FANG, Lei, JEON, Jaehyoung, SUNG, Eunsil, JEONG, Junhyun, JIANG, Wenqing
Year of Publication 07.06.2023
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Year of Publication 07.06.2023
Patent
ANTI-CLAUDIN 18.2 AND ANTI-4-1BB BISPECIFIC ANTIBODIES AND USES THEREOF
GUO, Bingshi, PARK, Eunyoung, SUNG, Byungje, FANG, Lei, SUNG, Eunsil, JIANG, Wenqing, WANG, Zhengyi
Year of Publication 29.06.2022
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Year of Publication 29.06.2022
Patent
Anti-claudin 18.2 and anti-4-1BB bispecific antibodies and uses thereof
Park, Eunyoung, Sung, Eunsil, Wang, Zhengyi, Fang, Lei, Jiang, Wenqing, Sung, Byungje, Guo, Bingshi
Year of Publication 01.03.2022
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Year of Publication 01.03.2022
Patent
Anti-alpha-synuclein antibodies and uses thereof
Kim, Yeunju, Ahn, Jinhyung, Kim, Tae Kyung, Eom, Jaehyun, An, Sungwon, Jung, Jinwon, Son, Yonggyu, Sung, Byungje, Kim, Juhee, Choi, Min Sun, Sung, Eunsil, Lee, Seung-Jae, Kim, Dongin, You, Weonkyoo, Jung, Jaeho, Lee, Sang Hoon
Year of Publication 30.07.2024
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Year of Publication 30.07.2024
Patent
ANTI-CLAUDIN 18.2 AND ANTI-4-IBB BISPECIFIC ANTIBODIES AND USES THEREOF
Park, Eunyoung, Sung, Eunsil, Wang, Zhengyi, Fang, Lei, Jiang, Wenqing, Sung, Byungje, Guo, Bingshi
Year of Publication 14.10.2021
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Year of Publication 14.10.2021
Patent
ANTI-PD-L1/ANTI-B7-H3 MULTISPECIFIC ANTIBODIES AND USES THEREOF
LEE, Sunju, PARK, Eunyoung, CUI, Feifei, SONG, Daehae, FANG, Lei, JEON, Jaehyoung, SUNG, Eunsil, JEONG, Junhyun, JIANG, Wenqing
Year of Publication 31.08.2022
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Year of Publication 31.08.2022
Patent
ANTI-CLL-1 ANTIBODIES AND USES THEREOF
PARK, Kyungjin, LEE, Yangsoon, KIM, Youngkwang, KWON, Junga, JEON, Jaehyoung, LEE, Eunhee, LEE, Suyoun, LEE, Shinai, LEE, Bora, PARK, Sumyeong, SUNG, Byungje, LIM, Yangmi, JUNG, Jinwon, KIM, Juhee, SUNG, Eunsil, YOO, Byeongmin
Year of Publication 29.05.2024
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Year of Publication 29.05.2024
Patent
ANTI-CLAUDIN 18.2 AND ANTI-4-1BB BISPECIFIC ANTIBODIES AND USES THEREOF
GUO, Bingshi, PARK, Eunyoung, SUNG, Byungje, FANG, Lei, SUNG, Eunsil, JIANG, Wenqing, WANG, Zhengyi
Year of Publication 28.07.2021
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Year of Publication 28.07.2021
Patent
Anti-PD-L1/anti-B7-H3 multispecific antibodies and uses thereof
LEE, Sunju, PARK, Eunyoung, CUI, Feifei, SONG, Daehae, FANG, Lei, JEON, Jaehyoung, SUNG, Eunsil, JEONG, Junhyun, JIANG, Wenqing
Year of Publication 26.05.2022
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Year of Publication 26.05.2022
Patent