Guanine-modified inhibitory oligonucleotides efficiently impair TLR7- and TLR9-mediated immune responses of human immune cells
Römmler, Franziska, Hammel, Monika, Waldhuber, Anna, Müller, Tina, Jurk, Marion, Uhlmann, Eugen, Wagner, Hermann, Vollmer, Jörg, Miethke, Thomas
Published in PloS one (19.02.2015)
Published in PloS one (19.02.2015)
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Uptake, Efficacy, and Systemic Distribution of Naked, Inhaled Short Interfering RNA (siRNA) and Locked Nucleic Acid (LNA) Antisense
Moschos, Sterghios A, Frick, Manfred, Taylor, Bruce, Turnpenny, Paul, Graves, Helen, Spink, Karen G, Brady, Kevin, Lamb, David, Collins, David, Rockel, Thomas D, Weber, Markus, Lazari, Ovadia, Perez-Tosar, Luis, Fancy, Sally A, Lapthorn, Chris, Green, Martin X, Evans, Steve, Selby, Matthew, Jones, Gareth, Jones, Lyn, Kearney, Sarah, Mechiche, Houria, Gikunju, Diana, Subramanian, Romesh, Uhlmann, Eugen, Jurk, Marion, Vollmer, Jörg, Ciaramella, Giuseppe, Yeadon, Michael
Published in Molecular therapy (01.12.2011)
Published in Molecular therapy (01.12.2011)
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Identification and quantification of GC-rich oligodeoxynucleotides in tissue extracts by capillary gel electrophoresis
Noll, Bernhard O., Debelak, Harald, Uhlmann, Eugen
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.03.2007)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.03.2007)
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Chemically Modified Oligonucleotides Modulate an Epigenetically Varied and Transient Form of Transcription Silencing of HIV-1 in Human Cells
Knowling, Stuart, Stapleton, Kenneth, Turner, Anne-Marie W, Uhlmann, Eugen, Lehmann, Thomas, Vollmer, Jörg, Morris, Kevin V
Published in Molecular therapy. Nucleic acids (2012)
Published in Molecular therapy. Nucleic acids (2012)
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The synthesis of polyamide nucleic acids using a novel monomethoxytrityl protecting-group strategy
Will, David W., Breipohl, Gerhard, Langner, Dietrich, Knolle, Jochen, Uhlmann, Eugen
Published in Tetrahedron (30.10.1995)
Published in Tetrahedron (30.10.1995)
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PNA: Synthetic Polyamide Nucleic Acids with Unusual Binding Properties
Uhlmann, Eugen, Peyman, Anusch, Breipohl, Gerhard, Will, David W.
Published in Angewandte Chemie (International ed.) (02.11.1998)
Published in Angewandte Chemie (International ed.) (02.11.1998)
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Enhancing antisense efficacy with multimers and multi-targeting oligonucleotides (MTOs) using cleavable linkers
Subramanian, Romesh R, Wysk, Mark A, Ogilvie, Kathleen M, Bhat, Abhijit, Kuang, Bing, Rockel, Thomas D, Weber, Markus, Uhlmann, Eugen, Krieg, Arthur M
Published in Nucleic acids research (30.10.2015)
Published in Nucleic acids research (30.10.2015)
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Guanine modification of inhibitory oligonucleotides potentiates their suppressive function
Römmler, Franziska, Jurk, Marion, Uhlmann, Eugen, Hammel, Monika, Waldhuber, Anna, Pfeiffer, Lavinia, Wagner, Hermann, Vollmer, Jörg, Miethke, Thomas
Published in The Journal of immunology (1950) (15.09.2013)
Published in The Journal of immunology (1950) (15.09.2013)
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Synthesis and properties of PNA/DNA chimeras
Uhlmann, E, Will, DW, Breipohl, G, Langner, D, Ryte, A
Published in Angewandte Chemie International Edition (01.12.1996)
Published in Angewandte Chemie International Edition (01.12.1996)
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Guanine-Modified Inhibitory Oligonucleotides Efficiently Impair TLR7- and TLR9-Mediated Immune Responses of Human Immune Cells: e0116703
Rommler, Franziska, Hammel, Monika, Waldhuber, Anna, Mueller, Tina, Jurk, Marion, Uhlmann, Eugen, Wagner, Hermann, Vollmer, Jorg, Miethke, Thomas
Published in PloS one (01.02.2015)
Published in PloS one (01.02.2015)
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Dual or Triple Activation of TLR7, TLR8, and/or TLR9 by Single-Stranded Oligoribonucleotides
Forsbach, Alexandra, Samulowitz, Ulrike, Völp, Kirsten, Hofmann, Hans-Peter, Noll, Bernhard, Tluk, Sybille, Schmitz, Claudia, Wader, Tanja, Müller, Christian, Podszuweit, Anja, Lohner, Angela, Curdt, Rainer, Uhlmann, Eugen, Vollmer, Jörg
Published in Nucleic acid therapeutics (01.12.2011)
Published in Nucleic acid therapeutics (01.12.2011)
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c-Cbl is downstream of c-Src in a signalling pathway necessary for bone resorption
Tanaka, Sakae, Amling, Michael, Neff, Lynn, Peyman, Anusch, Uhlmann, Eugen, Levy, Joan B, Baron, Roland
Published in Nature (London) (10.10.1996)
Published in Nature (London) (10.10.1996)
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C-Class CpG ODN: sequence requirements and characterization of immunostimulatory activities on mRNA level
Jurk, Marion, Schulte, Bettina, Kritzler, Andrea, Noll, Bernhard, Uhlmann, Eugen, Wader, Tanja, Schetter, Christian, Krieg, Arthur M., Vollmer, Jörg
Published in Immunobiology (1979) (01.01.2004)
Published in Immunobiology (1979) (01.01.2004)
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Biodistribution and metabolism of immunostimulatory oligodeoxynucleotide CPG 7909 in mouse and rat tissues following subcutaneous administration
Noll, Bernhard O., McCluskie, Michael J., Sniatala, Tanja, Lohner, Angela, Yuill, Stephanie, Krieg, Arthur M., Schetter, Christian, Davis, Heather L., Uhlmann, Eugen
Published in Biochemical pharmacology (15.03.2005)
Published in Biochemical pharmacology (15.03.2005)
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