Molecular basis of USP7 inhibition by selective small-molecule inhibitors
Turnbull, Andrew P., Ioannidis, Stephanos, Krajewski, Wojciech W., Pinto-Fernandez, Adan, Heride, Claire, Martin, Agnes C. L., Tonkin, Louise M., Townsend, Elizabeth C., Buker, Shane M., Lancia, David R., Caravella, Justin A., Toms, Angela V., Charlton, Thomas M., Lahdenranta, Johanna, Wilker, Erik, Follows, Bruce C., Evans, Nicola J., Stead, Lucy, Alli, Cristina, Zarayskiy, Vladislav V., Talbot, Adam C., Buckmelter, Alexandre J., Wang, Minghua, McKinnon, Crystal L., Saab, Fabienne, McGouran, Joanna F., Century, Hannah, Gersch, Malte, Pittman, Marc S., Marshall, C. Gary, Raynham, Tony M., Simcox, Mary, Stewart, Lorna M. D., McLoughlin, Sheila B., Escobedo, Jaime A., Bair, Kenneth W., Dinsmore, Christopher J., Hammonds, Tim R., Kim, Sunkyu, Urbé, Sylvie, Clague, Michael J., Kessler, Benedikt M., Komander, David
Published in Nature (London) (26.10.2017)
Published in Nature (London) (26.10.2017)
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Elevated Expression of axin2 and hnkd mRNA Provides Evidence That Wnt/β-Catenin Signaling is Activated in Human Colon Tumors
Yan, Dong, Wiesmann, Marion, Rohan, Michael, Chan, Vivien, Jefferson, Ann B., Guo, Lida, Sakamoto, Doreen, Caothien, Roger H., Fuller, John H., Reinhard, Christoph, Garcia, Pablo D., Randazzo, Filippo M., Escobedo, Jaime, Fantl, Wendy J., Williams, Lewis T.
Published in Proceedings of the National Academy of Sciences - PNAS (18.12.2001)
Published in Proceedings of the National Academy of Sciences - PNAS (18.12.2001)
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Journal Article
The fms-Like Tyrosine Kinase, a Receptor for Vascular Endothelial Growth Factor
De Vries, Carlie, Escobedo, Jaime A., Ueno, Hikaru, Houck, Keith, Ferrara, Napoleone, Williams, Lewis T.
Published in Science (American Association for the Advancement of Science) (21.02.1992)
Published in Science (American Association for the Advancement of Science) (21.02.1992)
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Journal Article
Regulation of chemotaxis by the platelet-derived growth factor receptor-β
Kundra, Vikas, Escobedo, Jaime A, Kazlauskas, Andrius, Kim, Ha Kun, Rhee, Sue Goo, Williams, Lewis T, Zetter, Bruce R
Published in Nature (London) (03.02.1994)
Published in Nature (London) (03.02.1994)
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Journal Article
Characterization of a New Member of the TNF Family Expressed on Antigen Presenting Cells
Tribouley, Catherine, Wallroth, Marco, Chan, Vivien, Paliard, Xavier, Fang, Eric, Lamson, George, Pot, David, Escobedo, Jaime, Williams, Lewis T.
Published in Biological chemistry (01.12.1999)
Published in Biological chemistry (01.12.1999)
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Tightly regulated long-term erythropoietin expression in vivo using tet-inducible recombinant adeno-associated viral vectors
Rendahl, Katherine G, Quiroz, Dulce, Ladner, Martha, Coyne, Mazie, Seltzer, Jon, Manning, William C, Escobedo, Jaime A
Published in Human gene therapy (20.01.2002)
Published in Human gene therapy (20.01.2002)
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Abstract 1268: A novel treatment approach for melanoma by dually targeting MCT1 and MCT4 lactate transporters
Sharma, Sambad, Goreczny, Gregory, Noonepalle, Satish Kumar, Palmer, Erica, Garcia-Hernandez, Maria, Banerjee, Daliya, Escobedo, Jaime, Villagra, Alejandro, Sandanayaka, Vincent
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Long-term correction of obesity and diabetes in genetically obese mice by a single intramuscular injection of recombinant adeno-associated virus encoding mouse leptin
Murphy, J.E, Zhou, S, Giese, K, Williams, L.T, Escobedo, J.A, Dwarki, V.J
Published in Proceedings of the National Academy of Sciences - PNAS (09.12.1997)
Published in Proceedings of the National Academy of Sciences - PNAS (09.12.1997)
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1355 Novel pharmacological approach to induce direct killing of cancer and activate antitumor immunity via inhibition of monocarboxylate transporters
Sharma, Sambad, Bowman, Nicole, Wijerathna, Sanath, Yu, Maolin, Duffy, Jennifer, Escobedo, Jaime, Kuklin, Nelly, Sandanayaka, Vincent
Published in Journal for immunotherapy of cancer (01.11.2022)
Published in Journal for immunotherapy of cancer (01.11.2022)
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1381 Lactate modulation in cancer and immune cells is associated with antitumor efficacy of dual MCT1/MCT4 inhibitor NGY-091
Bowman, Nicole, Sharma, Sambad, Duffy, Jennifer, Wijerathna, Sanath, Kuklin, Nelly, Escobedo, Jaime, Sandanayaka, Vincent
Published in Journal for immunotherapy of cancer (01.11.2022)
Published in Journal for immunotherapy of cancer (01.11.2022)
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Abstract 5126: Modulation of lactate in the tumor microenvironment with lactate transporter inhibitor in a melanoma syngeneic mouse model
Noonepalle, Satish Kumar Reddy, Kim, Jennifer, Hadley, Melissa, Palmer, Erica, Banik, Debarati, Knox, Tessa, Ephrame, Sophiya, Vembu, Prathima, Rudish, Summer, Moufarrij, Sara, Escobedo, Jaime, Sandanayaka, Vincent, Villagra, Alejandro
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Abstract P3-07-21: Therapeutic efficacy of NGY-091 against triple negative breast cancer is mediated by direct cell killing and activation of antitumor immunity
Sharma, Sambad, Wijerathna, Sanath, Wu, Kerui, Tyagi, Abhishek, Wu, Shih-Ying, Watabe, Kounosuke, Kuklin, Nelly, Escobedo, Jaime, Sandanayaka, Vincent
Published in Cancer research (Chicago, Ill.) (01.03.2023)
Published in Cancer research (Chicago, Ill.) (01.03.2023)
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Abstract 4053: NGY-B is a novel inhibitor of MCT transporters blocking lactate and glucose metabolisms
Sharma, Sambad, Goreczny, Gregory, Bowman, Nicole, Duffy, Jennifer, Banerjee, Daliya, Wijerathna, Sanath, Dzuris, John, Escobedo, Jaime, Sandanayaka, Vincent
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Abstract 2652: Efficacy of a small molecule MCT1 and MCT4 transporter inhibitor in cancer
Sharma, Sambad, Goreczny, Gregory, Bowman, Nicole, Duffy, Jennifer, Banerjee, Daliya, Wijerathna, Sanath, Dzuris, John, Wu, Kerui, Wu, Shih-Ying, Tyagi, Abhishek, Watabe, Kounosuke, Escobedo, Jaime, Sandanayaka, Vincent
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
β-catenin regulates vascular endothelial growth factor expression in colon cancer
EASWARAN, Vijay, LEE, Sang H, RANDAZZO, Filippo, GUNDEL, Robert, WARREN, Robert S, ESCOBEDO, Jaime, AUKERMAN, Sharon L, TAYLOR, Robert N, FANTL, Wendy J, INGE, Landon, LIDA GUO, GOLDBECK, Cheryl, GARRETT, Evelyn, WIESMANN, Marion, GARCIA, Pablo D, FULLER, John H, CHAN, Vivien
Published in Cancer research (Chicago, Ill.) (15.06.2003)
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Published in Cancer research (Chicago, Ill.) (15.06.2003)
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