Structure-based design of P3 moieties in the peptide mimetic factor VIIa inhibitor
Kadono, Shojiro, Sakamoto, Akihisa, Kikuchi, Yasufumi, Oh-eda, Masayoshi, Yabuta, Naohiro, Yoshihashi, Kazutaka, Kitazawa, Takehisa, Suzuki, Tsukasa, Koga, Takaki, Hattori, Kunihiro, Shiraishi, Takuya, Haramura, Masayuki, Kodama, Hirofumi, Ono, Yoshiyuki, Esaki, Toru, Sato, Haruhiko, Watanabe, Yoshiaki, Itoh, Susumu, Ohta, Masateru, Kozono, Toshiro
Published in Biochemical and biophysical research communications (11.02.2005)
Published in Biochemical and biophysical research communications (11.02.2005)
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Novel interactions of large P3 moiety and small P4 moiety in the binding of the peptide mimetic factor VIIa inhibitor
Kadono, Shojiro, Sakamoto, Akihisa, Kikuchi, Yasufumi, Oh-eda, Masayoshi, Yabuta, Naohiro, Yoshihashi, Kazutaka, Kitazawa, Takehisa, Suzuki, Tsukasa, Koga, Takaki, Hattori, Kunihiro, Shiraishi, Takuya, Haramura, Masayuki, Kodama, Hirofumi, Ono, Yoshiyuki, Esaki, Toru, Sato, Haruhiko, Watanabe, Yoshiaki, Itoh, Susumu, Ohta, Masateru, Kozono, Toshiro
Published in Biochemical and biophysical research communications (28.01.2005)
Published in Biochemical and biophysical research communications (28.01.2005)
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Journal Article
Synthesis and Biological Evaluations of Novel Human Parathyroid Hormone 1 Receptor (hPTHR1) Agonists Bearing Bicyclic Aromatic Moiety
Nishimura, Yoshikazu, Esaki, Toru, Isshiki, Yoshiaki, Furuta, Yoshiyuki, Emura, Takashi, Watanabe, Yoshiaki, Ohta, Masateru, Arai, Shinichi, Noda, Hiroshi, Shimizu, Masaru, Tamura, Tatsuya, Sato, Haruhiko
Published in ChemMedChem (01.03.2024)
Published in ChemMedChem (01.03.2024)
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Lead Optimization and Avoidance of Reactive Metabolite Leading to PCO371, a Potent, Selective, and Orally Available Human Parathyroid Hormone Receptor 1 (hPTHR1) Agonist
Nishimura, Yoshikazu, Esaki, Toru, Isshiki, Yoshiaki, Furuta, Yoshiyuki, Mizutani, Akemi, Kotake, Tomoya, Emura, Takashi, Watanabe, Yoshiaki, Ohta, Masateru, Nakagawa, Toshito, Ogawa, Kotaro, Arai, Shinichi, Noda, Hiroshi, Kitamura, Hidetomo, Shimizu, Masaru, Tamura, Tatsuya, Sato, Haruhiko
Published in Journal of medicinal chemistry (28.05.2020)
Published in Journal of medicinal chemistry (28.05.2020)
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Development of a Novel Human Parathyroid Hormone Receptor 1 (hPTHR1) Agonist (CH5447240), a Potent and Orally Available Small Molecule for Treatment of Hypoparathyroidism
Nishimura, Yoshikazu, Esaki, Toru, Isshiki, Yoshiaki, Okamoto, Naoki, Furuta, Yoshiyuki, Kotake, Tomoya, Watanabe, Yoshiaki, Ohta, Masateru, Nakagawa, Toshito, Noda, Hiroshi, Shimizu, Masaru, Saito, Hitoshi, Tamura, Tatsuya, Sato, Haruhiko
Published in Journal of medicinal chemistry (26.07.2018)
Published in Journal of medicinal chemistry (26.07.2018)
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Journal Article
Synthesis and Biological Evaluations of Novel Human Parathyroid Hormone 1Receptor (hPTHR1) Agonists Bearing Bicyclic Aromatic Moiety
Nishimura, Yoshikazu, Esaki, Toru, Isshiki, Yoshiaki, Furuta, Yoshiyuki, Emura, Takashi, Watanabe, Yoshiaki, Ohta, Masateru, Arai, Shinichi, Noda, Hiroshi, Shimizu, Masaru, Tamura, Tatsuya, Sato, Haruhiko
Published in ChemMedChem (26.01.2024)
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Published in ChemMedChem (26.01.2024)
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