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Wang, Zhizhi, Michaud, Gregory A, Cheng, Zhihong, Zhang, Yue, Hinds, Thomas R, Fan, Erkang, Cong, Feng, Xu, Wenqing
Published in Genes & development (01.02.2012)
Published in Genes & development (01.02.2012)
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Molecular Targets of the 5-Amido-Carboxamide Bumped Kinase Inhibitor BKI-1748 in Cryptosporidium parvum and HCT-8 Host Cells
Ajiboye, Jubilee, Uldry, Anne-Christine, Heller, Manfred, Naguleswaran, Arunasalam, Fan, Erkang, Van Voorhis, Wesley C, Hemphill, Andrew, Müller, Joachim
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Published in International journal of molecular sciences (26.02.2024)
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Bumped Kinase Inhibitor 1294 Treats Established Toxoplasma gondii Infection
STONE DOGGETT, J, OJO, Kayode K, FAN, Erkang, MALY, Dustin J, VAN VOORHIS, Wesley C
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Published in Antimicrobial agents and chemotherapy (01.06.2014)
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Novel Bumped Kinase Inhibitors Are Safe and Effective Therapeutics in the Calf Clinical Model for Cryptosporidiosis
Schaefer, Deborah A., Betzer, Dana P., Smith, Kylie D., Millman, Zachary G., Michalski, Hannah C., Menchaca, Sarah E., Zambriski, Jennifer A., Ojo, Kayode K., Hulverson, Matthew A., Arnold, Samuel L. M., Rivas, Kasey L., Vidadala, Rama S. R., Huang, Wenlin, Barrett, Lynn K., Maly, Dustin J., Fan, Erkang, Van Voorhis, Wesley C., Riggs, Michael W.
Published in The Journal of infectious diseases (15.12.2016)
Published in The Journal of infectious diseases (15.12.2016)
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A Specific Inhibitor of PfCDPK4 Blocks Malaria Transmission: Chemical-genetic Validation
Ojo, Kayode K., Eastman, Richard T., Vidadala, RamaSubbaRao, Zhang, Zhongsheng, Rivas, Kasey L., Choi, Ryan, Lutz, Justin D., Reid, Molly C., Fox, Anna M. W., Hulverson, Matthew A., Kennedy, Mark, Isoherranen, Nina, Kim, Laura M., Comess, Kenneth M., Kempf, Dale J., Verlinde, Christophe L. M. J., Su, Xin-zhuan, Kappe, Stefan H. I., Maly, Dustin J., Fan, Erkang, Van Voorhis, Wesley C.
Published in The Journal of infectious diseases (15.01.2014)
Published in The Journal of infectious diseases (15.01.2014)
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Recent advances in the DABOs family as potent HIV-1 non-nucleoside reverse transcriptase inhibitors
Yu, Mingyan, Fan, Erkang, Wu, Jingde, Liu, Xinyong
Published in Current medicinal chemistry (01.06.2011)
Published in Current medicinal chemistry (01.06.2011)
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Efficacy of the bumped kinase inhibitor BKI-1708 against the cyst-forming apicomplexan parasites Toxoplasma gondii and Neospora caninum in vitro and in experimentally infected mice
de Sousa, Maria Cristina Ferreira, Imhof, Dennis, Hänggeli, Kai Pascal Alexander, Choi, Ryan, Hulverson, Matthew A., Arnold, Samuel L.M., Van Voorhis, Wesley C., Fan, Erkang, Roberto, Sánchez-Sánchez, Ortega-Mora, Luis M., Hemphill, Andrew
Published in International journal for parasitology -- drugs and drug resistance (01.08.2024)
Published in International journal for parasitology -- drugs and drug resistance (01.08.2024)
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Solvent-Free or Low-Solvent Large-Scale Preparation of Chloropyrimidine and Analogues
Sun, Zhihua, Wang, Han, Wen, Kun, Li, Ya, Fan, Erkang
Published in Journal of organic chemistry (20.05.2011)
Published in Journal of organic chemistry (20.05.2011)
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Selective Inhibitors of Methionyl-tRNA Synthetase Have Potent Activity against Trypanosoma brucei Infection in Mice
SHIBATA, Sayaka, GILLESPIE, J. Robert, MERRITT, Ethan A, HOL, Wim G. J, VERLINDE, Christophe L. M. J, ERKANG FAN, BUCKNER, Frederick S, KELLEY, Angela M, NAPULI, Alberto J, ZHONGSHENG ZHANG, KOVZUN, Kuzma V, PEFLEY, Ranae M, LAM, Jocelyn, ZUCKER, Frank H, VAN VOORHIS, Wesley C
Published in Antimicrobial Agents and Chemotherapy (01.05.2011)
Published in Antimicrobial Agents and Chemotherapy (01.05.2011)
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Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis
Ojo, Kayode K, Ranade, Ranae M, Zhang, Zhongsheng, Dranow, David M, Myers, Janette B, Choi, Ryan, Nakazawa Hewitt, Steve, Edwards, Thomas E, Davies, Douglas R, Lorimer, Donald, Boyle, Stephen M, Barrett, Lynn K, Buckner, Frederick S, Fan, Erkang, Van Voorhis, Wesley C
Published in PloS one (08.08.2016)
Published in PloS one (08.08.2016)
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Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1
Larson, Eric T, Ojo, Kayode K, Murphy, Ryan C, Johnson, Steven M, Zhang, Zhongsheng, Kim, Jessica E, Leibly, David J, Fox, Anna M. W, Reid, Molly C, Dale, Edward J, Perera, B. Gayani K, Kim, Jae, Hewitt, Stephen N, Hol, Wim G. J, Verlinde, Christophe L. M. J, Fan, Erkang, Van Voorhis, Wesley C, Maly, Dustin J, Merritt, Ethan A
Published in Journal of medicinal chemistry (22.03.2012)
Published in Journal of medicinal chemistry (22.03.2012)
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Benzoylbenzimidazole-based selective inhibitors targeting Cryptosporidium parvum and Toxoplasma gondii calcium-dependent protein kinase-1
Zhang, Zhongsheng, Ojo, Kayode K., Johnson, Steven M., Larson, Eric T., He, Penqing, Geiger, Jennifer A., Castellanos-Gonzalez, Alejandro, White, A. Clinton, Parsons, Marilyn, Merritt, Ethan A., Maly, Dustin J., Verlinde, Christophe L.M.J., Van Voorhis, Wesley C., Fan, Erkang
Published in Bioorganic & medicinal chemistry letters (15.08.2012)
Published in Bioorganic & medicinal chemistry letters (15.08.2012)
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Structures of Trypanosoma brucei methionyl-tRNA synthetase with urea-based inhibitors provide guidance for drug design against sleeping sickness
Koh, Cho Yeow, Kim, Jessica E, Wetzel, Allan B, de van der Schueren, Will J, Shibata, Sayaka, Ranade, Ranae M, Liu, Jiyun, Zhang, Zhongsheng, Gillespie, J Robert, Buckner, Frederick S, Verlinde, Christophe L M J, Fan, Erkang, Hol, Wim G J
Published in PLoS neglected tropical diseases (01.04.2014)
Published in PLoS neglected tropical diseases (01.04.2014)
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Induced Resistance to Methionyl-tRNA Synthetase Inhibitors in Trypanosoma brucei Is Due to Overexpression of the Target
RANADE, Ranae M, GILLESPIE, J. Robert, SHIBATA, Sayaka, VERLINDE, Christophe L. M. J, FAN, Erkang, HOL, Wim G. J, BUCKNER, Frederick S
Published in Antimicrobial Agents and Chemotherapy (01.07.2013)
Published in Antimicrobial Agents and Chemotherapy (01.07.2013)
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Correction: Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis
Ojo, Kayode K, Ranade, Ranae M, Zhang, Zhongsheng, Dranow, David M, Myers, Janette B, Choi, Ryan, Nakazawa Hewitt, Steve, Edwards, Thomas E, Davies, Douglas R, Lorimer, Donald, Boyle, Stephen M, Barrett, Lynn K, Buckner, Frederick S, Fan, Erkang, Van Voorhis, Wesley C
Published in PloS one (22.09.2016)
Published in PloS one (22.09.2016)
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Characterization and Crystal Structure of a High-Affinity Pentavalent Receptor-Binding Inhibitor for Cholera Toxin and E. coli Heat-Labile Enterotoxin
MERRITT, Ethan A., ZHANG, Zhongsheng, PICKENS, Jason C., AHN, Misol, HOL, Wim G. J., FAN, Erkang
Published in Journal of the American Chemical Society (31.07.2002)
Published in Journal of the American Chemical Society (31.07.2002)
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Neospora caninum calcium-dependent protein kinase 1 is an effective drug target for neosporosis therapy
Ojo, Kayode K, Reid, Molly C, Kallur Siddaramaiah, Latha, Müller, Joachim, Winzer, Pablo, Zhang, Zhongsheng, Keyloun, Katelyn R, Vidadala, Rama Subba Rao, Merritt, Ethan A, Hol, Wim G J, Maly, Dustin J, Fan, Erkang, Van Voorhis, Wesley C, Hemphill, Andrew
Published in PloS one (28.03.2014)
Published in PloS one (28.03.2014)
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Solution and Crystallographic Studies of Branched Multivalent Ligands that Inhibit the Receptor-Binding of Cholera Toxin
Zhang, Zhongsheng, Merritt, Ethan A, Ahn, Misol, Roach, Claudia, Hou, Zheng, Verlinde, Christophe L. M. J, Hol, Wim G. J, Fan, Erkang
Published in Journal of the American Chemical Society (06.11.2002)
Published in Journal of the American Chemical Society (06.11.2002)
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