Methionine Aminopeptidase 2 Inhibition Is an Effective Treatment Strategy for Neuroblastoma in Preclinical Models
Morowitz, Michael J, Barr, Rosalind, Wang, Qun, King, Rebecca, Rhodin, Nicholas, Pawel, Bruce, Zhao, Huaqing, Erickson, Scott A, Sheppard, George S, Wang, Jieyi, Maris, John M, Shusterman, Suzanne
Published in Clinical cancer research (01.04.2005)
Published in Clinical cancer research (01.04.2005)
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Imidazo[2,1- b]thiazoles: Multitargeted inhibitors of both the insulin-like growth factor receptor and members of the epidermal growth factor family of receptor tyrosine kinases
Fidanze, Steve D., Erickson, Scott A., Wang, Gary T., Mantei, Robert, Clark, Richard F., Sorensen, Bryan K., Bamaung, Nwe Y., Kovar, Peter, Johnson, Eric F., Swinger, Kerren K., Stewart, Kent D., Zhang, Qian, Tucker, Lora A., Pappano, William N., Wilsbacher, Julie L., Wang, Jieyi, Sheppard, George S., Bell, Randy L., Davidsen, Steven K., Hubbard, Robert D.
Published in Bioorganic & medicinal chemistry letters (15.04.2010)
Published in Bioorganic & medicinal chemistry letters (15.04.2010)
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Discovery and Optimization of Anthranilic Acid Sulfonamides as Inhibitors of Methionine Aminopeptidase-2: A Structural Basis for the Reduction of Albumin Binding
Sheppard, George S, Wang, Jieyi, Kawai, Megumi, Fidanze, Steve D, BaMaung, Nwe Y, Erickson, Scott A, Barnes, David M, Tedrow, Jason S, Kolaczkowski, Lawrence, Vasudevan, Anil, Park, David C, Wang, Gary T, Sanders, William J, Mantei, Robert A, Palazzo, Fabio, Tucker-Garcia, Lora, Lou, Pingping, Zhang, Qian, Park, Chang H, Kim, Ki H, Petros, Andrew, Olejniczak, Edward, Nettesheim, David, Hajduk, Phillip, Henkin, Jack, Lesniewski, Richard, Davidsen, Steven K, Bell, Randy L
Published in Journal of medicinal chemistry (29.06.2006)
Published in Journal of medicinal chemistry (29.06.2006)
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Tumor suppression by a rationally designed reversible inhibitor of methionine aminopeptidase-2
JIEYI WANG, SHEPPARD, George S, FROST, David, TAPANG, Paul, ALBERT, Daniel H, MORGAN, Sherry J, MOROWITZ, Michael, SHUSTERMAN, Suzanne, MARIS, John M, LESNIEWSKI, Rick, HENKIN, Jack, PINGPING LOU, KAWAI, Megumi, BAMAUNG, Nwe, ERICKSON, Scott A, TUCKER-GARCIA, Lora, CHANG PARK, BOUSKA, Jennifer, WANG, Yi-Chun
Published in Cancer research (Chicago, Ill.) (15.11.2003)
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Published in Cancer research (Chicago, Ill.) (15.11.2003)
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Development of sulfonamide compounds as potent methionine aminopeptidase type II inhibitors with antiproliferative properties
Kawai, Megumi, BaMaung, Nwe Y., Fidanze, Steve D., Erickson, Scott A., Tedrow, Jason S., Sanders, William J., Vasudevan, Anil, Park, Chang, Hutchins, Charles, Comess, Kenneth M., Kalvin, Douglas, Wang, Jieyi, Zhang, Qian, Lou, Pingping, Tucker-Garcia, Lora, Bouska, Jennifer, Bell, Randy L., Lesniewski, Richard, Henkin, Jack, Sheppard, George S.
Published in Bioorganic & medicinal chemistry letters (01.07.2006)
Published in Bioorganic & medicinal chemistry letters (01.07.2006)
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Development of multitargeted inhibitors of both the insulin-like growth factor receptor (IGF-IR) and members of the epidermal growth factor family of receptor tyrosine kinases
HUBBARD, Robert D, BAMAUNG, Nwe Y, OSTERLING, Donald J, JOHNSON, Eric F, BOUSKA, Jennifer, JIEYI WANG, DAVIDSEN, Steven K, BELL, Randy L, SHEPPARD, George S, FIDANZE, Steve D, ERICKSON, Scott A, PALAZZO, Fabio, WILSBACHER, Julie L, QIAN ZHANG, TUCKER, Lora A, XIAOMING HU, KOVAR, Peter
Published in Bioorganic & medicinal chemistry letters (15.03.2009)
Published in Bioorganic & medicinal chemistry letters (15.03.2009)
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Journal Article
3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2
SHEPPARD, George S, JIEYI WANG, PINGPING LOU, CHANG PARK, KIM, Ki H, HENKIN, Jack, LESNIEWSKI, Richard, KAWAI, Megumi, BAMAUNG, Nwe Y, CRAIG, Richard A, ERICKSON, Scott A, LYNCH, Linda, PATEL, Jyoti, FAN YANG, SEARLE, Xenia B
Published in Bioorganic & medicinal chemistry letters (23.02.2004)
Published in Bioorganic & medicinal chemistry letters (23.02.2004)
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Effects of Lattice Segmentation on Microtubule Mechanics
Erickson, Scott A., Isozaki, Naoto, Ross, Jennifer, Hawkins, Taviare
Published in Biophysical journal (16.02.2016)
Published in Biophysical journal (16.02.2016)
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Abstract A245: Imidazo[2,1-b]thiazole and imidazo[1,2-a]pyridine amides as novel inhibitors of the insulin-like growth factor (IGF1R) and members of the epidermal growth factor family of tyrosine kinases
Fidanze, Steve D., Erickson, Scott A., Hubbard, Robert D., Wang, Gary T., Mantei, Robert A., BaMaung, Nwe Y., Clark, Richard F., Sorensen, Bryan K., Kovar, Peter, Pappano, William, Zhang, Qian, Wilsbacher, Julie L., Hu, Xiaoming, Tucker, Lora A., Cheng, Min, Swinger, Kerren K., Stewart, Kent D., Wang, Jieyi, Bell, Randy L., Davidsen, Steven K., Sheppard, George S.
Published in Molecular cancer therapeutics (10.12.2009)
Published in Molecular cancer therapeutics (10.12.2009)
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Journal Article
Methionine aminopeptidase 2 inhibition is an effectivetreatment strategy for neuroblastoma in preclinical models
MOROWITZ, Michael J, BARR, Rosalind, MARIS, John M, SHUSTERMAN, Suzanne, QUN WANG, KING, Rebecca, RHODIN, Nicholas, PAWEL, Bruce, HUAQING ZHAO, ERICKSON, Scott A, SHEPPARD, George S, JIEYI WANG
Published in Clinical cancer research (2005)
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Published in Clinical cancer research (2005)
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PYRIMIDINE INHIBITORS OF KINASE ACTIVITY
SHEPPARD, GEORGE, S, MANTEI, ROBERT, A, FIDANZE, STEVE, D, BELL, RANDY, L, WANG, GARY, T, ERICKSON, SCOTT, A, WANG, JIEYI
Year of Publication 17.12.2014
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Year of Publication 17.12.2014
Patent
Pyrimidine inhibitors of kinase activity
BELL RANDY L, WANG GARY T, MANTEI ROBERT A, FIDANZE STEVE D, SHEPPARD GEORGE S, ERICKSON SCOTT A, WANG JIEYI
Year of Publication 16.07.2013
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Year of Publication 16.07.2013
Patent
Imidazopyridines as a novel scaffold for multi-targeted kinase inhibition
MANTEI ROBERT A, WANG GARY T, BA-MAUNG NWE Y, FIDANZE STEVE D, SHEPPARD GEORGE S, SORENSEN BRYAN K, ERICKSON SCOTT A, CLARK RICHARD F, KAWAI MEGUMI
Year of Publication 09.06.2015
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Year of Publication 09.06.2015
Patent
PYRIMIDINE INHIBITORS OF KINASE ACTIVITY
SHEPPARD, GEORGE, S, MANTEI, ROBERT, A, FIDANZE, STEVE, D, BELL, RANDY, L, WANG, GARY, T, ERICKSON, SCOTT, A, WANG, JIEYI
Year of Publication 04.04.2012
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Year of Publication 04.04.2012
Patent
PYRIMIDINE INHIBITORS OF KINASE ACTIVITY
SHEPPARD, GEORGE, S, FIDANZE, STEVE, D, MANTEI, ROBERT, A, BELL, RANDY, L, WANG, GARY, T, SORENSEN, BRYAN, K, BA-MAUNG, NWE, Y, ERICKSON, SCOTT, A, CLARK, RICHARD, F, WANG, JIEYI
Year of Publication 30.07.2014
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Year of Publication 30.07.2014
Patent