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The Structure of Crystalline Agnotobenzaldehyde
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Inhibitors of NF-κB and AP-1 Gene Expression: SAR Studies on the Pyrimidine Portion of 2-Chloro-4-trifluoromethylpyrimidine-5-[N-(3‘,5‘-bis(trifluoromethyl)phenyl)carboxamide]
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Nagy, Mark A, Hilgraf, Robert, Mortensen, Deborah S, Elsner, Jan, Norris, Stephen, Tikhe, Jayashree, Yoon, Won, Paisner, David, Delgado, Mercedes, Erdman, Paul, Haelewyn, Jason, Khambatta, Godrej, Xu, Li, Romanow, William J, Condroski, Kevin, Bahmanyar, Sogole, McCarrick, Meg, Benish, Brent, Blease, Kate, LeBrun, Laurie, Moghaddam, Mehran F, Apuy, Julius, Canan, Stacie S, Bennett, Brydon L, Satoh, Yoshitaka
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The Discovery of a Dual TTK Protein Kinase/CDC2-Like Kinase (CLK2) Inhibitor for the Treatment of Triple Negative Breast Cancer Initiated from a Phenotypic Screen
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Published in Journal of medicinal chemistry (09.11.2017)
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2-Chloro-4-(trifluoromethyl)pyrimidine-5-N-(3‘,5‘-bis(trifluoromethyl)phenyl)- carboxamide: A Potent Inhibitor of NF-κB- and AP-1-Mediated Gene Expression Identified Using Solution-Phase Combinatorial Chemistry
Sullivan, Robert W, Bigam, Colin G, Erdman, Paul E, Palanki, Moorthy S. S, Anderson, David W, Goldman, Mark E, Ransone, Lynn J, Suto, Mark J
Published in Journal of medicinal chemistry (12.02.1998)
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Targeting AML: The Development of Two Functionally and Mechanistically Distinct Classes of Cereblon-Mediated Protein Homeostatic Modulators
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Bioavailable Dual-Protein Degraders of CK1α and Transcriptional Kinase CDK9 As Potential Therapeutics for Hematological Malignancies
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Discovery of SARxxxx92, a pan-PIM kinase inhibitor, efficacious in a KG1 tumor model
Barberis, Claude, Erdman, Paul, Czekaj, Mark, Fire, Luke, Pribish, James, Tserlin, Elina, Maniar, Sachin, Batchelor, Joseph D., Liu, Jinyu, Patel, Vinod F., Hebert, Andrew, Levit, Mikhail, Wang, Anlai, Sun, Frank, Huang, Shih-Min A.
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Barberis, Claude, Pribish, James, Tserlin, Elina, Gross, Alexandre, Czekaj, Mark, Barragué, Matthieu, Erdman, Paul, Maniar, Sachin, Jiang, John, Fire, Luke, Patel, Vinod, Hebert, Andrew, Levit, Mikhail, Wang, Anlai, Sun, Frank, Huang, Shih-Min A.
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Published in Bioorganic & medicinal chemistry letters (01.02.2019)
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Protein Homeostatic Modulators, a Novel Class of Cereblon-Targeting Small Molecules As Potential Clinical Candidates in Multiple Myeloma
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Published in Blood (08.12.2017)
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Year of Publication 02.03.2022
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Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches
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Published in ACS chemical biology (19.06.2009)
Published in ACS chemical biology (19.06.2009)
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