Local regulation of gene expression by lncRNA promoters, transcription and splicing
Engreitz, Jesse M., Haines, Jenna E., Perez, Elizabeth M., Munson, Glen, Chen, Jenny, Kane, Michael, McDonel, Patrick E., Guttman, Mitchell, Lander, Eric S.
Published in Nature (London) (17.11.2016)
Published in Nature (London) (17.11.2016)
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Transcriptome-wide Mapping Reveals Widespread Dynamic-Regulated Pseudouridylation of ncRNA and mRNA
Schwartz, Schraga, Bernstein, Douglas A., Mumbach, Maxwell R., Jovanovic, Marko, Herbst, Rebecca H., León-Ricardo, Brian X., Engreitz, Jesse M., Guttman, Mitchell, Satija, Rahul, Lander, Eric S., Fink, Gerald, Regev, Aviv
Published in Cell (25.09.2014)
Published in Cell (25.09.2014)
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Journal Article
RNA-RNA Interactions Enable Specific Targeting of Noncoding RNAs to Nascent Pre-mRNAs and Chromatin Sites
Engreitz, Jesse M., Sirokman, Klara, McDonel, Patrick, Shishkin, Alexander A., Surka, Christine, Russell, Pamela, Grossman, Sharon R., Chow, Amy Y., Guttman, Mitchell, Lander, Eric S.
Published in Cell (25.09.2014)
Published in Cell (25.09.2014)
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The Lin28/let-7 Axis Regulates Glucose Metabolism
Zhu, Hao, Shyh-Chang, Ng, Segrè, Ayellet V., Shinoda, Gen, Shah, Samar P., Einhorn, William S., Takeuchi, Ayumu, Engreitz, Jesse M., Hagan, John P., Kharas, Michael G., Urbach, Achia, Thornton, James E., Triboulet, Robinson, Gregory, Richard I., Altshuler, David, Daley, George Q.
Published in Cell (30.09.2011)
Published in Cell (30.09.2011)
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Activity-by-contact model of enhancer–promoter regulation from thousands of CRISPR perturbations
Fulco, Charles P., Nasser, Joseph, Jones, Thouis R., Munson, Glen, Bergman, Drew T., Subramanian, Vidya, Grossman, Sharon R., Anyoha, Rockwell, Doughty, Benjamin R., Patwardhan, Tejal A., Nguyen, Tung H., Kane, Michael, Perez, Elizabeth M., Durand, Neva C., Lareau, Caleb A., Stamenova, Elena K., Aiden, Erez Lieberman, Lander, Eric S., Engreitz, Jesse M.
Published in Nature genetics (01.12.2019)
Published in Nature genetics (01.12.2019)
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Journal Article
The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome
Engreitz, Jesse M, Pandya-Jones, Amy, McDonel, Patrick, Shishkin, Alexander, Sirokman, Klara, Surka, Christine, Kadri, Sabah, Xing, Jeffrey, Goren, Alon, Lander, Eric S, Plath, Kathrin, Guttman, Mitchell
Published in Science (American Association for the Advancement of Science) (16.08.2013)
Published in Science (American Association for the Advancement of Science) (16.08.2013)
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Journal Article
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability
Munschauer, Mathias, Nguyen, Celina T., Sirokman, Klara, Hartigan, Christina R., Hogstrom, Larson, Engreitz, Jesse M., Ulirsch, Jacob C., Fulco, Charles P., Subramanian, Vidya, Chen, Jenny, Schenone, Monica, Guttman, Mitchell, Carr, Steven A., Lander, Eric S.
Published in Nature (London) (01.09.2018)
Published in Nature (London) (01.09.2018)
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Journal Article
Recurrent and functional regulatory mutations in breast cancer
Rheinbay, Esther, Parasuraman, Prasanna, Grimsby, Jonna, Tiao, Grace, Engreitz, Jesse M., Kim, Jaegil, Lawrence, Michael S., Taylor-Weiner, Amaro, Rodriguez-Cuevas, Sergio, Rosenberg, Mara, Hess, Julian, Stewart, Chip, Maruvka, Yosef E., Stojanov, Petar, Cortes, Maria L., Seepo, Sara, Cibulskis, Carrie, Tracy, Adam, Pugh, Trevor J., Lee, Jesse, Zheng, Zongli, Ellisen, Leif W., Iafrate, A. John, Boehm, Jesse S., Gabriel, Stacey B., Meyerson, Matthew, Golub, Todd R., Baselga, Jose, Hidalgo-Miranda, Alfredo, Shioda, Toshi, Bernards, Andre, Lander, Eric S., Getz, Gad
Published in Nature (London) (06.07.2017)
Published in Nature (London) (06.07.2017)
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Journal Article
KLF4 recruits SWI/SNF to increase chromatin accessibility and reprogram the endothelial enhancer landscape under laminar shear stress
Moonen, Jan-Renier, Chappell, James, Shi, Minyi, Shinohara, Tsutomu, Li, Dan, Mumbach, Maxwell R., Zhang, Fan, Nair, Ramesh V., Nasser, Joseph, Mai, Daniel H., Taylor, Shalina, Wang, Lingli, Metzger, Ross J., Chang, Howard Y., Engreitz, Jesse M., Snyder, Michael P., Rabinovitch, Marlene
Published in Nature communications (23.08.2022)
Published in Nature communications (23.08.2022)
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Journal Article
Reduced FOXF1 links unrepaired DNA damage to pulmonary arterial hypertension
Isobe, Sarasa, Nair, Ramesh V., Kang, Helen Y., Wang, Lingli, Moonen, Jan-Renier, Shinohara, Tsutomu, Cao, Aiqin, Taylor, Shalina, Otsuki, Shoichiro, Marciano, David P., Harper, Rebecca L., Adil, Mir S., Zhang, Chongyang, Lago-Docampo, Mauro, Körbelin, Jakob, Engreitz, Jesse M., Snyder, Michael P., Rabinovitch, Marlene
Published in Nature communications (21.11.2023)
Published in Nature communications (21.11.2023)
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Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features
Ray, John P., de Boer, Carl G., Fulco, Charles P., Lareau, Caleb A., Kanai, Masahiro, Ulirsch, Jacob C., Tewhey, Ryan, Ludwig, Leif S., Reilly, Steven K., Bergman, Drew T., Engreitz, Jesse M., Issner, Robbyn, Finucane, Hilary K., Lander, Eric S., Regev, Aviv, Hacohen, Nir
Published in Nature communications (06.03.2020)
Published in Nature communications (06.03.2020)
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Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis
Nandakumar, Satish K, McFarland, Sean K, Mateyka, Laura M, Lareau, Caleb A, Ulirsch, Jacob C, Ludwig, Leif S, Agarwal, Gaurav, Engreitz, Jesse M, Przychodzen, Bartlomiej, McConkey, Marie, Cowley, Glenn S, Doench, John G, Maciejewski, Jaroslaw P, Ebert, Benjamin L, Root, David E, Sankaran, Vijay G
Published in eLife (09.05.2019)
Published in eLife (09.05.2019)
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Computational estimates of annular diameter reveal genetic determinants of mitral valve function and disease
Yu, Mengyao, Tcheandjieu, Catherine, Georges, Adrien, Xiao, Ke, Tejeda, Helio, Dina, Christian, Le Tourneau, Thierry, Fiterau, Madalina, Judy, Renae, Tsao, Noah L, Amgalan, Dulguun, Munger, Chad J, Engreitz, Jesse M, Damrauer, Scott M, Bouatia-Naji, Nabila, Priest, James R
Published in JCI insight (08.02.2022)
Published in JCI insight (08.02.2022)
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Content-based microarray search using differential expression profiles
Engreitz, Jesse M, Morgan, Alexander A, Dudley, Joel T, Chen, Rong, Thathoo, Rahul, Altman, Russ B, Butte, Atul J
Published in BMC bioinformatics (21.12.2010)
Published in BMC bioinformatics (21.12.2010)
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Journal Article
Discovering metabolic disease gene interactions by correlated effects on cellular morphology
Jiao, Yang, Ahmed, Umer, Sim, M.F. Michelle, Bejar, Andrea, Zhang, Xiaolan, Talukder, M. Mesbah Uddin, Rice, Robert, Flannick, Jason, Podgornaia, Anna I., Reilly, Dermot F., Engreitz, Jesse M., Kost-Alimova, Maria, Hartland, Kate, Mercader, Josep-Maria, Georges, Sara, Wagh, Vilas, Tadin-Strapps, Marija, Doench, John G., Edwardson, J. Michael, Rochford, Justin J., Rosen, Evan D., Majithia, Amit R.
Published in Molecular metabolism (Germany) (01.06.2019)
Published in Molecular metabolism (Germany) (01.06.2019)
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Journal Article
Systematic mapping of functional enhancer-promoter connections with CRISPR interference
Fulco, Charles P., Munschauer, Mathias, Anyoha, Rockwell, Munson, Glen, Grossman, Sharon R., Perez, Elizabeth M., Kane, Michael, Cleary, Brian, Lander, Eric S., Engreitz, Jesse M.
Published in Science (American Association for the Advancement of Science) (11.11.2016)
Published in Science (American Association for the Advancement of Science) (11.11.2016)
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Journal Article
Cohesin Loss Eliminates All Loop Domains
Rao, Suhas S.P., Huang, Su-Chen, Glenn St Hilaire, Brian, Engreitz, Jesse M., Perez, Elizabeth M., Kieffer-Kwon, Kyong-Rim, Sanborn, Adrian L., Johnstone, Sarah E., Bascom, Gavin D., Bochkov, Ivan D., Huang, Xingfan, Shamim, Muhammad S., Shin, Jaeweon, Turner, Douglass, Ye, Ziyi, Omer, Arina D., Robinson, James T., Schlick, Tamar, Bernstein, Bradley E., Casellas, Rafael, Lander, Eric S., Aiden, Erez Lieberman
Published in Cell (05.10.2017)
Published in Cell (05.10.2017)
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