Thalassaemia
Higgs, Douglas R, Prof, Engel, James Douglas, Prof, Stamatoyannopoulos, George, Prof
Published in The Lancet (British edition) (28.01.2012)
Published in The Lancet (British edition) (28.01.2012)
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Journal Article
A Single Kinase Generates the Majority of the Secreted Phosphoproteome
Tagliabracci, Vincent S., Wiley, Sandra E., Guo, Xiao, Kinch, Lisa N., Durrant, Eric, Wen, Jianzhong, Xiao, Junyu, Cui, Jixin, Nguyen, Kim B., Engel, James L., Coon, Joshua J., Grishin, Nick, Pinna, Lorenzo A., Pagliarini, David J., Dixon, Jack E.
Published in Cell (18.06.2015)
Published in Cell (18.06.2015)
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Nrf2-MafG heterodimers contribute globally to antioxidant and metabolic networks
Hirotsu, Yosuke, Katsuoka, Fumiki, Funayama, Ryo, Nagashima, Takeshi, Nishida, Yuichiro, Nakayama, Keiko, Engel, James Douglas, Yamamoto, Masayuki
Published in Nucleic acids research (01.11.2012)
Published in Nucleic acids research (01.11.2012)
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Journal Article
A Remote GATA2 Hematopoietic Enhancer Drives Leukemogenesis in inv(3)(q21;q26) by Activating EVI1 Expression
Yamazaki, Hiromi, Suzuki, Mikiko, Otsuki, Akihito, Shimizu, Ritsuko, Bresnick, Emery H., Engel, James Douglas, Yamamoto, Masayuki
Published in Cancer cell (14.04.2014)
Published in Cancer cell (14.04.2014)
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Journal Article
Dynamic regulation of FGF23 by Fam20C phosphorylation, GalNAc-T3 glycosylation, and furin proteolysis
Tagliabracci, Vincent S, Engel, James L, Wiley, Sandra E, Xiao, Junyu, Gonzalez, David J, Nidumanda Appaiah, Hitesh, Koller, Antonius, Nizet, Victor, White, Kenneth E, Dixon, Jack E
Published in Proceedings of the National Academy of Sciences - PNAS (15.04.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (15.04.2014)
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Rare variant discovery by deep whole-genome sequencing of 1,070 Japanese individuals
Nagasaki, Masao, Yasuda, Jun, Katsuoka, Fumiki, Nariai, Naoki, Kojima, Kaname, Kawai, Yosuke, Yamaguchi-Kabata, Yumi, Yokozawa, Junji, Danjoh, Inaho, Saito, Sakae, Sato, Yukuto, Mimori, Takahiro, Tsuda, Kaoru, Saito, Rumiko, Pan, Xiaoqing, Nishikawa, Satoshi, Ito, Shin, Kuroki, Yoko, Tanabe, Osamu, Fuse, Nobuo, Kuriyama, Shinichi, Kiyomoto, Hideyasu, Hozawa, Atsushi, Minegishi, Naoko, Douglas Engel, James, Kinoshita, Kengo, Kure, Shigeo, Yaegashi, Nobuo, Yamamoto, Masayuki
Published in Nature communications (21.08.2015)
Published in Nature communications (21.08.2015)
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Journal Article
Secreted Kinase Phosphorylates Extracellular Proteins That Regulate Biomineralization
Tagliabracci, Vincent S., Engel, James L., Wen, Jianzhong, Wiley, Sandra E., Worby, Carolyn A., Kinch, Lisa N., Xiao, Junyu, Grishin, Nick V., Dixon, Jack E.
Published in Science (American Association for the Advancement of Science) (01.06.2012)
Published in Science (American Association for the Advancement of Science) (01.06.2012)
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Journal Article
Oral tetrahydrouridine and decitabine for non-cytotoxic epigenetic gene regulation in sickle cell disease: A randomized phase 1 study
Molokie, Robert, Lavelle, Donald, Gowhari, Michel, Pacini, Michael, Krauz, Lani, Hassan, Johara, Ibanez, Vinzon, Ruiz, Maria A, Ng, Kwok Peng, Woost, Philip, Radivoyevitch, Tomas, Pacelli, Daisy, Fada, Sherry, Rump, Matthew, Hsieh, Matthew, Tisdale, John F, Jacobberger, James, Phelps, Mitch, Engel, James Douglas, Saraf, Santhosh, Hsu, Lewis L, Gordeuk, Victor, DeSimone, Joseph, Saunthararajah, Yogen
Published in PLoS medicine (07.09.2017)
Published in PLoS medicine (07.09.2017)
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Mitochondrial Phosphatase PTPMT1 Is Essential for Cardiolipin Biosynthesis
Zhang, Ji, Guan, Ziqiang, Murphy, Anne N., Wiley, Sandra E., Perkins, Guy A., Worby, Carolyn A., Engel, James L., Heacock, Philip, Nguyen, Oanh Kim, Wang, Jonathan H., Raetz, Christian R.H., Dowhan, William, Dixon, Jack E.
Published in Cell metabolism (08.06.2011)
Published in Cell metabolism (08.06.2011)
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Analysis of cardiomyocyte clonal expansion during mouse heart development and injury
Sereti, Konstantina-Ioanna, Nguyen, Ngoc B., Kamran, Paniz, Zhao, Peng, Ranjbarvaziri, Sara, Park, Shuin, Sabri, Shan, Engel, James L., Sung, Kevin, Kulkarni, Rajan P., Ding, Yichen, Hsiai, Tzung K., Plath, Kathrin, Ernst, Jason, Sahoo, Debashis, Mikkola, Hanna K.A., Iruela-Arispe, M. Luisa, Ardehali, Reza
Published in Nature communications (21.02.2018)
Published in Nature communications (21.02.2018)
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In situ mapping identifies distinct vascular niches for myelopoiesis
Zhang, Jizhou, Wu, Qingqing, Johnson, Courtney B., Pham, Giang, Kinder, Jeremy M., Olsson, Andre, Slaughter, Anastasiya, May, Margot, Weinhaus, Benjamin, D’Alessandro, Angelo, Engel, James Douglas, Jiang, Jean X., Kofron, J. Matthew, Huang, L. Frank, Prasath, V. B. Surya, Way, Sing Sing, Salomonis, Nathan, Grimes, H. Leighton, Lucas, Daniel
Published in Nature (London) (18.02.2021)
Published in Nature (London) (18.02.2021)
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FIP200 is required for the cell-autonomous maintenance of fetal hematopoietic stem cells
Liu, Fei, Lee, Jae Y., Wei, Huijun, Tanabe, Osamu, Engel, James D., Morrison, Sean J., Guan, Jun-Lin
Published in Blood (02.12.2010)
Published in Blood (02.12.2010)
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Journal Article
Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome
Wang, Xiaorong, Cimermancic, Peter, Yu, Clinton, Schweitzer, Andreas, Chopra, Nikita, Engel, James L., Greenberg, Charles, Huszagh, Alexander S., Beck, Florian, Sakata, Eri, Yang, Yingying, Novitsky, Eric J., Leitner, Alexander, Nanni, Paolo, Kahraman, Abdullah, Guo, Xing, Dixon, Jack E., Rychnovsky, Scott D., Aebersold, Ruedi, Baumeister, Wolfgang, Sali, Andrej, Huang, Lan
Published in Molecular & cellular proteomics (01.05.2017)
Published in Molecular & cellular proteomics (01.05.2017)
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High‐level induction of fetal haemoglobin by pomalidomide in β‐thalassaemia/HbE erythroid progenitor cells
Khamphikham, Pinyaphat, Nualkaew, Tiwaporn, Pongpaksupasin, Phitchapa, Kaewsakulthong, Woratree, Songdej, Duantida, Paiboonsukwong, Kittiphong, Engel, James D., Hongeng, Suradej, Fucharoen, Suthat, Sripichai, Orapan, Jearawiriyapaisarn, Natee
Published in British journal of haematology (01.06.2020)
Published in British journal of haematology (01.06.2020)
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Isolation and characterization of human embryonic stem cell-derived heart field-specific cardiomyocytes unravels new insights into their transcriptional and electrophysiological profiles
Pezhouman, Arash, Engel, James L, Nguyen, Ngoc B, Skelton, Rhys J P, Gilmore, William Blake, Qiao, Rong, Sahoo, Debashis, Zhao, Peng, Elliott, David A, Ardehali, Reza
Published in Cardiovascular research (21.02.2022)
Published in Cardiovascular research (21.02.2022)
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