Inhibition of N-myristoyltransferase activity promotes androgen receptor degradation in prostate cancer
Alsaidan, Omar Awad, Onobun, Emmanuel, Ye, Chenming, Lou, Lei, Beharry, Zanna, Xie, Zhong-Ru, Lebedyeva, Iryna, Crich, David, Cai, Houjian
Published in The Prostate (01.02.2024)
Published in The Prostate (01.02.2024)
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Journal Article
CGAS INHIBITOR
JOTHIRAJAH MARIMUTHU, THIBAULT FRANCOIS VARIN, SCOTT EUGENE CONNER, CHERYL ANN CARSON, ERIC GEORGE TROMICZAK, FRANCISCO JAVIER AGEJAS CHICHARRO, SHANTHI NAGARAJAN, CHARLES W LUGAR, CHRISTINA MARTINEZ BROKAW, EMMANUEL ONOBUN, ADEL AHMED, STEVEN J GREEN, GRAHAM ROBERT CUMMING, KEVIN CHARLES FORTNER, DOUGLAS L GERNERT
Year of Publication 03.07.2024
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Year of Publication 03.07.2024
Patent
CGAS INHIBITOR
CHARLES W LUGAR III, ERIC G TROMICZAK, JOTHIRAJAH MARIMUTHU, CHERYL ANN CARSON, THIBAULT VARIN, SHANTHI NAGARAJAN, CHRISTODOULOS NICOLAOU, STEPHANIE LANGE STOUT, CHRISTINA MARTINEZ BROKAW, EMMANUEL ONOBUN, JEFFRY B FRANCISKOVICH, ADEL AHMED, SCOTT E CONNER, STEVEN J GREEN, KEVIN CHARLES FORTNER, DOUGLAS L GERNERT
Year of Publication 19.12.2023
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Year of Publication 19.12.2023
Patent
Exploring Noncovalent Protease Inhibitors for the Treatment of Severe Acute Respiratory Syndrome and Severe Acute Respiratory Syndrome-Like Coronaviruses
Freitas, Brendan T, Ahiadorme, Daniil A, Bagul, Rahul S, Durie, Ian A, Ghosh, Samir, Hill, Jarvis, Kramer, Naomi E, Murray, Jackelyn, O’Boyle, Brady M, Onobun, Emmanuel, Pirrone, Michael G, Shepard, Justin D, Enos, Suzanne, Subedi, Yagya P, Upadhyaya, Kapil, Tripp, Ralph A, Cummings, Brian S, Crich, David, Pegan, Scott D
Published in ACS infectious diseases (11.03.2022)
Published in ACS infectious diseases (11.03.2022)
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Journal Article
Exploring noncovalent protease inhibitors for the treatment of SARS and SARS-like coronaviruses
Freitas, Brendan T., Ahiadorme, Daniil A., Bagul, Rahul S., Durie, Ian A., Ghosh, Samir, Hill, Jarvis, Kramer, Naomi E., Murray, Jackelyn, O’Boyle, Brady M., Onobun, Emmanuel, Pirrone, Michael G., Shepard, Justin D., Enos, Suzanne, Subedi, Yagya P., Upadhyaya, Kapil, Tripp, Ralph A., Cummings, Brian S., Crich, David, Pegan, Scott D.
Published in ACS infectious diseases (24.02.2022)
Published in ACS infectious diseases (24.02.2022)
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Journal Article
cGAS INHIBITORS
AHMED, Adel, GERNERT, Douglas L, CARSON, Cheryl Ann, TROMICZAK, Eric George, LUGAR, Charles W, FORTNER, Kevin Charles, ONOBUN, Emmanuel, CUMMING, Graham Robert, AGEJAS CHICHARRO, Francisco Javier, NAGARAJAN, Shanthi, MARTINEZ BROKAW, Christina, VARIN, Thibault Francois, GREEN, Steven J, CONNER, Scott Eugene, MARIMUTHU, Jothirajah
Year of Publication 25.07.2024
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Year of Publication 25.07.2024
Patent
AZEPINO[4,5-B]INDOLONE CGAS INHIBITORS
AHMED, Adel, GERNERT, Douglas L, CARSON, Cheryl Ann, TROMICZAK, Eric George, LUGAR, Charles W, FORTNER, Kevin Charles, ONOBUN, Emmanuel, CUMMING, Graham Robert, AGEJAS CHICHARRO, Francisco Javier, NAGARAJAN, Shanthi, MARTINEZ BROKAW, Christina, VARIN, Thibault Francois, GREEN, Steven J, CONNER, Scott Eugene, MARIMUTHU, Jothirajah
Year of Publication 27.06.2024
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Year of Publication 27.06.2024
Patent
COMPOSITIONS AND METHODS OF TREATMENT FOR SARS-COV-2 THROUGH PAPAIN PROTEASE INHIBITION
AHIADORME, Daniil, CUMMINGS, Brian, DURIE, Ian, UPADHYAYA, Kapil, PEGAN, Scott, ONOBUN, Emmanuel, BAGUL, Rahul, FREITAS, Brendan, SUBEDI, Yagya, TRIPP, Ralph, PIRRONE, Mike, CRICH, David, HILL, Jarvis
Year of Publication 07.04.2022
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Year of Publication 07.04.2022
Patent
cGAS INHIBITORS
CONNER, Scott E, AHMED, Adel, GERNERT, Douglas L, NICOLAOU, Christodoulos, CARSON, Cheryl Ann, FRANCISKOVICH, Jeffry B, FORTNER, Kevin Charles, ONOBUN, Emmanuel, STOUT, Stephanie Lange, LUGAR, III, Charles W, NAGARAJAN, Shanthi, VARIN, Thibault, MARTINEZ BROKAW, Christina, GREEN, Steven J, TROMICZAK, Eric G, MARIMUTHU, Jothirajah
Year of Publication 07.12.2023
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Year of Publication 07.12.2023
Patent
CGAS INHIBITORS
CONNER, Scott E, AHMED, Adel, GERNERT, Douglas L, NICOLAOU, Christodoulos, CARSON, Cheryl Ann, LUGAR, Charles W. III, FRANCISKOVICH, Jeffry B, FORTNER, Kevin Charles, ONOBUN, Emmanuel, STOUT, Stephanie Lange, NAGARAJAN, Shanthi, VARIN, Thibault, MARTINEZ BROKAW, Christina, GREEN, Steven J, TROMICZAK, Eric G, MARIMUTHU, Jothirajah
Year of Publication 07.12.2023
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Year of Publication 07.12.2023
Patent
INHIBIDORES DE CGAS
NAGARAJAN, SHANTHI, FORTNER, KEVIN CHARLES, ONOBUN, EMMANUEL, GERNERT, DOUGLAS L, NICOLAOU, CHRISTODOULOS, MARTINEZ BROKAW, CHRISTINA, LUGAR III, CHARLES W, AHMED, ADEL, TROMICZAK, ERIC G, FRANCISKOVICH, JEFFRY B, VARIN, THIBAULT, CARSON, CHERYL ANN, STOUT, STEPHANIE LANGE, MARIMUTHU, JOTHIRAJAH, CONNER, SCOTT E, GREEN, STEVEN J
Year of Publication 04.09.2024
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Year of Publication 04.09.2024
Patent
cGAS inhibitors
NAGARAJAN, SHANTHI, FORTNER, KEVIN CHARLES, ONOBUN, EMMANUEL, GERNERT, DOUGLAS L, NICOLAOU, CHRISTODOULOS, MARTINEZ BROKAW, CHRISTINA, AHMED, ADEL, TROMICZAK, ERIC G, FRANCISKOVICH, JEFFRY B, VARIN, THIBAULT, CARSON, CHERYL ANN, STOUT, STEPHANIE LANGE, LUGAR, CHARLES W, MARIMUTHU, JOTHIRAJAH, CONNER, SCOTT E, GREEN, STEVEN J
Year of Publication 01.05.2024
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Year of Publication 01.05.2024
Patent