Indenoisoquinoline Topoisomerase Inhibitors Strongly Bind and Stabilize the MYC Promoter G‑Quadruplex and Downregulate MYC
Wang, Kai-Bo, Elsayed, Mohamed S. A, Wu, Guanhui, Deng, Nanjie, Cushman, Mark, Yang, Danzhou
Published in Journal of the American Chemical Society (17.07.2019)
Published in Journal of the American Chemical Society (17.07.2019)
Get full text
Journal Article
Novel Fluoroindenoisoquinoline Non-Camptothecin Topoisomerase I Inhibitors
Marzi, Laetitia, Agama, Keli, Murai, Junko, Difilippantonio, Simone, James, Amy, Peer, Cody J, Figg, William D, Beck, Daniel, Elsayed, Mohamed S A, Cushman, Mark, Pommier, Yves
Published in Molecular cancer therapeutics (01.08.2018)
Published in Molecular cancer therapeutics (01.08.2018)
Get full text
Journal Article
Design, Synthesis, and Biological Evaluation of Potential Prodrugs Related to the Experimental Anticancer Agent Indotecan (LMP400)
Lv, Peng-Cheng, Elsayed, Mohamed S. A, Agama, Keli, Marchand, Christophe, Pommier, Yves, Cushman, Mark
Published in Journal of medicinal chemistry (26.05.2016)
Published in Journal of medicinal chemistry (26.05.2016)
Get full text
Journal Article
Applying ligands profiling using multiple extended electron distribution based field templates and feature trees similarity searching in the discovery of new generation of urea-based antineoplastic kinase inhibitors
Dokla, Eman M, Mahmoud, Amr H, Elsayed, Mohamed S A, El-Khatib, Ahmed H, Linscheid, Michael W, Abouzid, Khaled A
Published in PloS one (20.11.2012)
Published in PloS one (20.11.2012)
Get full text
Journal Article
Synthesis and Biological Evaluation of the First Triple Inhibitors of Human Topoisomerase 1, Tyrosyl–DNA Phosphodiesterase 1 (Tdp1), and Tyrosyl–DNA Phosphodiesterase 2 (Tdp2)
Wang, Ping, Elsayed, Mohamed S. A, Plescia, Caroline B, Ravji, Azhar, Redon, Christophe E, Kiselev, Evgeny, Marchand, Christophe, Zeleznik, Olga, Agama, Keli, Pommier, Yves, Cushman, Mark
Published in Journal of medicinal chemistry (27.04.2017)
Published in Journal of medicinal chemistry (27.04.2017)
Get full text
Journal Article
Design and Synthesis of Chlorinated and Fluorinated 7‑Azaindenoisoquinolines as Potent Cytotoxic Anticancer Agents That Inhibit Topoisomerase I
Elsayed, Mohamed S. A, Su, Yafan, Wang, Ping, Sethi, Taresh, Agama, Keli, Ravji, Azhar, Redon, Christophe E, Kiselev, Evgeny, Horzmann, Katharine A, Freeman, Jennifer L, Pommier, Yves, Cushman, Mark
Published in Journal of medicinal chemistry (13.07.2017)
Published in Journal of medicinal chemistry (13.07.2017)
Get full text
Journal Article
Application of Sequential Palladium Catalysis for the Discovery of Janus Kinase Inhibitors in the Benzo[c]pyrrolo[2,3‑h][1,6]naphthyridin-5-one (BPN) Series
Elsayed, Mohamed S. A, Nielsen, Jeffery J, Park, Sungtae, Park, Jeongho, Liu, Qingyang, Kim, Chang H, Pommier, Yves, Agama, Keli, Low, Philip S, Cushman, Mark
Published in Journal of medicinal chemistry (13.12.2018)
Published in Journal of medicinal chemistry (13.12.2018)
Get full text
Journal Article
Analyzing the Influence of eWOM on Customer Perception of Value and Brand Love in Hospitality Enterprise
Alshreef, Mohamed A, Hassan, Thowayeb H, Helal, Mohamed Y, Saleh, Mahmoud I, Tatiana, Palei, Alrefae, Wael M, Elshawarbi, Nabila N, Al-Saify, Hassan N, Salem, Amany E, Elsayed, Mohamed A. S
Published in Sustainability (27.04.2023)
Published in Sustainability (27.04.2023)
Get full text
Journal Article
Isolation and characterization of Salmonella Enteritidis and Salmonella Typhimurium from chicken meat in Egypt
Tarabees, Reda, Elsayed, Mohamed S A, Shawish, Reyad, Basiouni, Shereen, Shehata, Awad A
Published in Journal of infection in developing countries (30.04.2017)
Published in Journal of infection in developing countries (30.04.2017)
Get full text
Journal Article
Service Value and Repurchase Intention in the Egyptian Fast-Food Restaurants: Toward a New Measurement Model
Doeim, Abdelhalim R, Hassan, Thowayeb H, Helal, Mohamed Y, Saleh, Mahmoud I, Salem, Amany E, Elsayed, Mohamed A S
Published in International journal of environmental research and public health (27.11.2022)
Published in International journal of environmental research and public health (27.11.2022)
Get full text
Journal Article
Antioxidant and Antibacterial Activities of Silver Nanoparticles Biosynthesized by Moringa oleifera through Response Surface Methodology
Mohammed, A. B. Abeer, Mohamed, Amr, El-Naggar, Noura El-Ahmady, Mahrous, Hoda, Nasr, Ghada M., Abdella, Asmaa, Ahmed, Rasha H., Irmak, Sibel, Elsayed, Mohamed S. A., Selim, Samy, Elkelish, Amr, Alkhalifah, Dalal Hussien M., Hozzein, Wael N., Ali, Abdallah S.
Published in Journal of nanomaterials (2022)
Published in Journal of nanomaterials (2022)
Get full text
Journal Article
Discovery of Pyrazolopyrazines as Selective, Potent, and Mutant-Active MET Inhibitors with Intracranial Efficacy
Bumpers, Quinn A., Pipal, Robert W., Benz-Weeden, Anna M., Brewster, James T., Cook, Adam, Crooks, Amy L., Cruz, Cole, Dwulet, Natalie C., Gaudino, John J., Golec, Daniel, Harrison, Jacqueline A., Hartley, Dylan P., Hassanien, Sherif H., Hicken, Erik J., Kahn, Dean, Laird, Ellen R., Lemieux, Christine, Lewandowski, Nicholas, McCown, Joseph, McDonald, Matthew G., McNulty, Oren, Mou, Tung-Chung, Nguyen, Phong, Oko, Lauren, Opie, Lisa Pieti, Otten, Jennifer, Peck, Spencer C., Polites, Viktor C., Randall, Samuel D., Rosen, Rachel Z., Savechenkov, Pavel, Simpson, Helen, Singh, Anurag, Sparks, Drew, Wickersham, Kyle, Wollenberg, Lance, Wong, Christina E., Wong, Jim, Wu, Wen-I, Elsayed, Mohamed S. A., Hinklin, Ronald J., Tang, Tony P.
Published in Journal of medicinal chemistry (22.08.2024)
Published in Journal of medicinal chemistry (22.08.2024)
Get full text
Journal Article
Discovery of 5‑Azaquinoxaline Derivatives as Potent and Orally Bioavailable Allosteric SHP2 Inhibitors
Elsayed, Mohamed S. A., Blake, James F., Boys, Mark L., Brown, Eric, Chapsal, Bruno D., Chicarelli, Mark J., Cook, Adam W., Fell, Jay B., Fischer, John P., Hanson, Lauren, Lemieux, Christine, Martinson, Matthew C., McCown, Joseph, McNulty, Oren T., Mejia, Macedonio J., Neitzel, Nickolas A., Otten, Jennifer N., Rodriguez, Martha E., Wilcox, Daniel, Wong, Christina E., Zhou, Yeyun, Hinklin, Ronald J.
Published in ACS medicinal chemistry letters (14.12.2023)
Published in ACS medicinal chemistry letters (14.12.2023)
Get full text
Journal Article
Design, synthesis and molecular modeling study of certain 4-Methylbenzenesulfonamides with CDK2 inhibitory activity as anticancer and radio-sensitizing agents
Ghorab, Mostafa M., Ragab, Fatma A., Heiba, Helmy I., Elsayed, Mohamed S.A., Ghorab, Walid M.
Published in Bioorganic chemistry (01.10.2018)
Published in Bioorganic chemistry (01.10.2018)
Get full text
Journal Article
Structure-based design and synthesis of novel pseudosaccharine derivatives as antiproliferative agents and kinase inhibitors
Elsayed, Mohamed S.A., El-Araby, Moustafa E., Serya, Rabah A.T., El-Khatib, Ahmed H., Linscheid, Michael W., Abouzid, Khaled A.M.
Published in European journal of medicinal chemistry (01.03.2013)
Published in European journal of medicinal chemistry (01.03.2013)
Get full text
Journal Article
단백질 티로신 포스파타제 억제제
HINKLIN RONALD JAY, JIANG YUTONG, MEJIA MACEDONIO J, FISCHER JOHN P, MCNULTY OREN T, FELL JAY BRADFORD, BOYS MARK LAURENCE, WONG CHRISTINA E, COOK ADAM W, BLAKE JAMES F, ELSAYED MOHAMED S. A, RODRIGUEZ MARTHA E, CHICARELLI MARK JOSEPH
Year of Publication 03.12.2021
Get full text
Year of Publication 03.12.2021
Patent
단백질 티로신 포스파타제 억제제
HINKLIN RONALD JAY, MEJIA MACEDONIO J, FISCHER JOHN P, MCNULTY OREN T, RODRIGUEZ MARTHA E, BOYS MARK LAURENCE, FELL JAY B, WONG CHRISTINA E, CHICARELLI MARK JOSEPH, BLAKE JAMES F, COOK ADAM, ELSAYED MOHAMED S. A
Year of Publication 23.06.2021
Get full text
Year of Publication 23.06.2021
Patent