Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages
Gautier, Emmanuel L, Shay, Tal, Miller, Jennifer, Greter, Melanie, Jakubzick, Claudia, Ivanov, Stoyan, Helft, Julie, Chow, Andrew, Elpek, Kutlu G, Gordonov, Simon, Mazloom, Amin R, Ma'ayan, Avi, Chua, Wei-Jen, Hansen, Ted H, Turley, Shannon J, Merad, Miriam, Randolph, Gwendalyn J
Published in Nature immunology (01.11.2012)
Published in Nature immunology (01.11.2012)
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Journal Article
Regulated release of nitric oxide by nonhematopoietic stroma controls expansion of the activated T cell pool in lymph nodes
Lukacs-Kornek, Veronika, Malhotra, Deepali, Fletcher, Anne L, Acton, Sophie E, Elpek, Kutlu G, Tayalia, Prakriti, Collier, Ai-ris, Turley, Shannon J
Published in Nature immunology (01.11.2011)
Published in Nature immunology (01.11.2011)
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Journal Article
The stromal and haematopoietic antigen-presenting cells that reside in secondary lymphoid organs
Turley, Shannon J, Fletcher, Anne L, Elpek, Kutlu G
Published in Nature reviews. Immunology (01.12.2010)
Published in Nature reviews. Immunology (01.12.2010)
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Journal Article
Deciphering the transcriptional network of the dendritic cell lineage
Miller, Jennifer C, Brown, Brian D, Shay, Tal, Gautier, Emmanuel L, Jojic, Vladimir, Cohain, Ariella, Pandey, Gaurav, Leboeuf, Marylene, Elpek, Kutlu G, Helft, Julie, Hashimoto, Daigo, Chow, Andrew, Price, Jeremy, Greter, Melanie, Bogunovic, Milena, Bellemare-Pelletier, Angelique, Frenette, Paul S, Randolph, Gwendalyn J, Turley, Shannon J, Merad, Miriam
Published in Nature immunology (01.09.2012)
Published in Nature immunology (01.09.2012)
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Journal Article
Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks
Malhotra, Deepali, Fletcher, Anne L, Astarita, Jillian, Lukacs-Kornek, Veronika, Tayalia, Prakriti, Gonzalez, Santiago F, Elpek, Kutlu G, Chang, Sook Kyung, Knoblich, Konstantin, Hemler, Martin E, Brenner, Michael B, Carroll, Michael C, Mooney, David J, Turley, Shannon J
Published in Nature immunology (01.05.2012)
Published in Nature immunology (01.05.2012)
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Journal Article
IgE/FcεRI-Mediated Antigen Cross-Presentation by Dendritic Cells Enhances Anti-Tumor Immune Responses
Platzer, Barbara, Elpek, Kutlu G., Cremasco, Viviana, Baker, Kristi, Stout, Madeleine M., Schultz, Cornelia, Dehlink, Eleonora, Shade, Kai-Ting C., Anthony, Robert M., Blumberg, Richard S., Turley, Shannon J., Fiebiger, Edda
Published in Cell reports (Cambridge) (10.03.2015)
Published in Cell reports (Cambridge) (10.03.2015)
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Journal Article
Podoplanin-Rich Stromal Networks Induce Dendritic Cell Motility via Activation of the C-type Lectin Receptor CLEC-2
Acton, Sophie E., Astarita, Jillian L., Malhotra, Deepali, Lukacs-Kornek, Veronika, Franz, Bettina, Hess, Paul R., Jakus, Zoltan, Kuligowski, Michael, Fletcher, Anne L., Elpek, Kutlu G., Bellemare-Pelletier, Angelique, Sceats, Lindsay, Reynoso, Erika D., Gonzalez, Santiago F., Graham, Daniel B., Chang, Jonathan, Peters, Anneli, Woodruff, Matthew, Kim, Young-A., Swat, Wojciech, Morita, Takashi, Kuchroo, Vijay, Carroll, Michael C., Kahn, Mark L., Wucherpfennig, Kai W., Turley, Shannon J.
Published in Immunity (Cambridge, Mass.) (24.08.2012)
Published in Immunity (Cambridge, Mass.) (24.08.2012)
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Journal Article
ICOS agonism by JTX-2011 (vopratelimab) requires initial T cell priming and Fc cross-linking for optimal T cell activation and anti-tumor immunity in preclinical models
Hanson, Amanda, Elpek, Kutlu, Duong, Ellen, Shallberg, Lindsey, Fan, Martin, Johnson, Calvin, Wallace, Matthew, Mabry, George R., Sazinsky, Stephen, Pepper, Lauren, Shu, Chengyi J., Sathyanarayanan, Sriram, Zuerndorfer, Sarah, Simpson, Tyler, Gostissa, Monica, Briskin, Michael, Law, Deborah, Michaelson, Jennifer, Harvey, Christopher J.
Published in PloS one (24.09.2020)
Published in PloS one (24.09.2020)
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Mutations in G protein β subunits promote transformation and kinase inhibitor resistance
Yoda, Akinori, Adelmant, Guillaume, Tamburini, Jerome, Chapuy, Bjoern, Shindoh, Nobuaki, Yoda, Yuka, Weigert, Oliver, Kopp, Nadja, Wu, Shuo-Chieh, Kim, Sunhee S, Liu, Huiyun, Tivey, Trevor, Christie, Amanda L, Elpek, Kutlu G, Card, Joseph, Gritsman, Kira, Gotlib, Jason, Deininger, Michael W, Makishima, Hideki, Turley, Shannon J, Javidi-Sharifi, Nathalie, Maciejewski, Jaroslaw P, Jaiswal, Siddhartha, Ebert, Benjamin L, Rodig, Scott J, Tyner, Jeffrey W, Marto, Jarrod A, Weinstock, David M, Lane, Andrew A
Published in Nature medicine (01.01.2015)
Published in Nature medicine (01.01.2015)
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Journal Article
Intestinal Tolerance Is Converted to Autoimmune Enteritis upon PD-1 Ligand Blockade
Reynoso, Erika D, Elpek, Kutlu G, Francisco, Loise, Bronson, Roderick, Bellemare-Pelletier, Angelique, Sharpe, Arlene H, Freeman, Gordon J, Turley, Shannon J
Published in The Journal of immunology (1950) (15.02.2009)
Published in The Journal of immunology (1950) (15.02.2009)
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Journal Article
PTEN is a major tumor suppressor in pancreatic ductal adenocarcinoma and regulates an NF-κB-cytokine network
Ying, Haoqiang, Elpek, Kutlu G, Vinjamoori, Anant, Zimmerman, Stephanie M, Chu, Gerald C, Yan, Haiyan, Fletcher-Sananikone, Eliot, Zhang, Hailei, Liu, Yingchun, Wang, Wei, Ren, Xiaojia, Zheng, Hongwu, Kimmelman, Alec C, Paik, Ji-hye, Lim, Carol, Perry, Samuel R, Jiang, Shan, Malinn, Brian, Protopopov, Alexei, Colla, Simona, Xiao, Yonghong, Hezel, Aram F, Bardeesy, Nabeel, Turley, Shannon J, Wang, Y Alan, Chin, Lynda, Thayer, Sarah P, DePinho, Ronald A
Published in Cancer discovery (01.07.2011)
Published in Cancer discovery (01.07.2011)
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Journal Article
The tumor microenvironment shapes lineage, transcriptional, and functional diversity of infiltrating myeloid cells
Elpek, Kutlu G, Cremasco, Viviana, Shen, Hua, Harvey, Christopher J, Wucherpfennig, Kai W, Goldstein, Daniel R, Monach, Paul A, Turley, Shannon J
Published in Cancer immunology research (01.07.2014)
Published in Cancer immunology research (01.07.2014)
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Journal Article
Interleukin-15/interleukin-15R alpha complexes promote destruction of established tumors by reviving tumor-resident CD8+ T cells
Epardaud, Mathieu, Elpek, Kutlu G, Rubinstein, Mark P, Yonekura, Ai-ris, Bellemare-Pelletier, Angelique, Bronson, Roderick, Hamerman, Jessica A, Goldrath, Ananda W, Turley, Shannon J
Published in Cancer research (Chicago, Ill.) (15.04.2008)
Published in Cancer research (Chicago, Ill.) (15.04.2008)
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Journal Article
Lymphoid organ-resident dendritic cells exhibit unique transcriptional fingerprints based on subset and site
Elpek, Kutlu G, Bellemare-Pelletier, Angelique, Malhotra, Deepali, Reynoso, Erika D, Lukacs-Kornek, Veronika, DeKruyff, Rosemarie H, Turley, Shannon J
Published in PloS one (19.08.2011)
Published in PloS one (19.08.2011)
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Journal Article
Ex Vivo Expansion of CD4+CD25+FoxP3+ T Regulatory Cells Based on Synergy between IL-2 and 4-1BB Signaling
Elpek, Kutlu G, Yolcu, Esma S, Franke, Deanna D. H, Lacelle, Chantale, Schabowsky, Rich-Henry, Shirwan, Haval
Published in The Journal of immunology (1950) (01.12.2007)
Published in The Journal of immunology (1950) (01.12.2007)
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Journal Article
CD4+CD25+ T Regulatory Cells Dominate Multiple Immune Evasion Mechanisms in Early but Not Late Phases of Tumor Development in a B Cell Lymphoma Model
Elpek, Kutlu G, Lacelle, Chantale, Singh, Narendra P, Yolcu, Esma S, Shirwan, Haval
Published in The Journal of immunology (1950) (01.06.2007)
Published in The Journal of immunology (1950) (01.06.2007)
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Journal Article
Costimulation as a platform for the development of vaccines: a peptide-based vaccine containing a novel form of 4-1BB ligand eradicates established tumors
Sharma, Rajesh K, Elpek, Kutlu G, Yolcu, Esma S, Schabowsky, Rich-Henry, Zhao, Hong, Bandura-Morgan, Laura, Shirwan, Haval
Published in Cancer research (Chicago, Ill.) (15.05.2009)
Published in Cancer research (Chicago, Ill.) (15.05.2009)
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Journal Article
4-1BB Ligand as an Effective Multifunctional Immunomodulator and Antigen Delivery Vehicle for the Development of Therapeutic Cancer Vaccines
SHARMA, Rajesh K, SCHABOWSKY, Rich-Henry, SHIRWAN, Haval, SRIVASTAVA, Abhishek K, ELPEK, Kutlu G, MADIREDD, Shravan, HONG ZHAO, ZHENPING ZHONG, MILLER, Robert W, MACLEOD, Kathryn J, YOLCU, Esma S
Published in Cancer research (Chicago, Ill.) (15.05.2010)
Published in Cancer research (Chicago, Ill.) (15.05.2010)
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Journal Article
Diminished metastasis in tetraspanin CD151–knockout mice
Takeda, Yoshito, Li, Qinglin, Kazarov, Alexander R., Epardaud, Mathieu, Elpek, Kutlu, Turley, Shannon J., Hemler, Martin E.
Published in Blood (14.07.2011)
Published in Blood (14.07.2011)
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Journal Article
Mature natural killer cells with phenotypic and functional alterations accumulate upon sustained stimulation with IL-15/IL-15Rα complexes
Elpek, Kutlu G., Rubinstein, Mark P., Bellemare-Pelletier, Angelique, Goldrath, Ananda W., Turley, Shannon J., Cantor, Harvey
Published in Proceedings of the National Academy of Sciences - PNAS (14.12.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (14.12.2010)
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