Precision targeting of autoantigen-specific B cells in muscle-specific tyrosine kinase myasthenia gravis with chimeric autoantibody receptor T cells
Oh, Sangwook, Mao, Xuming, Manfredo-Vieira, Silvio, Lee, Jinmin, Patel, Darshil, Choi, Eun Jung, Alvarado, Andrea, Cottman-Thomas, Ebony, Maseda, Damian, Tsao, Patricia Y., Ellebrecht, Christoph T., Khella, Sami L., Richman, David P., O’Connor, Kevin C., Herzberg, Uri, Binder, Gwendolyn K., Milone, Michael C., Basu, Samik, Payne, Aimee S.
Published in Nature biotechnology (01.09.2023)
Published in Nature biotechnology (01.09.2023)
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Antigen-specific B cell depletion for precision therapy of mucosal pemphigus vulgaris
Lee, Jinmin, Lundgren, Daniel K, Mao, Xuming, Manfredo-Vieira, Silvio, Nunez-Cruz, Selene, Williams, Erik F, Assenmacher, Charles-Antoine, Radaelli, Enrico, Oh, Sangwook, Wang, Baomei, Ellebrecht, Christoph T, Fraietta, Joseph A, Milone, Michael C, Payne, Aimee S
Published in The Journal of clinical investigation (01.12.2020)
Published in The Journal of clinical investigation (01.12.2020)
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Supraphysiologic control over HIV-1 replication mediated by CD8 T cells expressing a re-engineered CD4-based chimeric antigen receptor
Leibman, Rachel S, Richardson, Max W, Ellebrecht, Christoph T, Maldini, Colby R, Glover, Joshua A, Secreto, Anthony J, Kulikovskaya, Irina, Lacey, Simon F, Akkina, Sarah R, Yi, Yanjie, Shaheen, Farida, Wang, Jianbin, Dufendach, Keith A, Holmes, Michael C, Collman, Ronald G, Payne, Aimee S, Riley, James L
Published in PLoS pathogens (01.10.2017)
Published in PLoS pathogens (01.10.2017)
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Autoreactive IgG and IgA B Cells Evolve through Distinct Subclass Switch Pathways in the Autoimmune Disease Pemphigus Vulgaris
Ellebrecht, Christoph T., Mukherjee, Eric M., Zheng, Qi, Choi, Eun Jung, Reddy, Shantan G., Mao, Xuming, Payne, Aimee S.
Published in Cell reports (Cambridge) (28.08.2018)
Published in Cell reports (Cambridge) (28.08.2018)
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Pathogenicity and Epitope Characteristics Do Not Differ in IgG Subclass-Switched Anti-Desmoglein 3 IgG1 and IgG4 Autoantibodies in Pemphigus Vulgaris
Lo, Agnes S, Mao, Xuming, Mukherjee, Eric M, Ellebrecht, Christoph T, Yu, Xiaocong, Posner, Marshall R, Payne, Aimee S, Cavacini, Lisa A
Published in PloS one (01.06.2016)
Published in PloS one (01.06.2016)
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Receptor repertoires of murine follicular T helper cells reveal a high clonal overlap in separate lymph nodes in autoimmunity
Niebuhr, Markus, Belde, Julia, Fähnrich, Anke, Serge, Arnauld, Irla, Magali, Ellebrecht, Christoph T, Hammers, Christoph M, Bieber, Katja, Westermann, Jürgen, Kalies, Kathrin
Published in eLife (17.08.2021)
Published in eLife (17.08.2021)
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Complement-fixing anti-type VII collagen antibodies are induced in Th1-polarized lymph nodes of epidermolysis bullosa acquisita-susceptible mice
Hammers, Christoph M, Bieber, Katja, Kalies, Kathrin, Banczyk, David, Ellebrecht, Christoph T, Ibrahim, Saleh M, Zillikens, Detlef, Ludwig, Ralf J, Westermann, Jürgen
Published in The Journal of immunology (1950) (15.11.2011)
Published in The Journal of immunology (1950) (15.11.2011)
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Pemphigus and Pemphigoid: From Disease Mechanisms to Druggable Pathways
Ellebrecht, Christoph T., Maseda, Damian, Payne, Aimee S.
Published in Journal of investigative dermatology (01.03.2022)
Published in Journal of investigative dermatology (01.03.2022)
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Reengineering chimeric antigen receptor T cells for targeted therapy of autoimmune disease
Ellebrecht, Christoph T., Bhoj, Vijay G., Nace, Arben, Choi, Eun Jung, Mao, Xuming, Cho, Michael Jeffrey, Di Zenzo, Giovanni, Lanzavecchia, Antonio, Seykora, John T., Cotsarelis, George, Milone, Michael C., Payne, Aimee S.
Published in Science (American Association for the Advancement of Science) (08.07.2016)
Published in Science (American Association for the Advancement of Science) (08.07.2016)
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Pemphigus
Kasperkiewicz, Michael, Ellebrecht, Christoph T., Takahashi, Hayato, Yamagami, Jun, Zillikens, Detlef, Payne, Aimee S., Amagai, Masayuki
Published in Nature reviews. Disease primers (11.05.2017)
Published in Nature reviews. Disease primers (11.05.2017)
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Shared VH1-46 gene usage by pemphigus vulgaris autoantibodies indicates common humoral immune responses among patients
Cho, Michael Jeffrey, Lo, Agnes S.Y., Mao, Xuming, Nagler, Arielle R., Ellebrecht, Christoph T., Mukherjee, Eric M., Hammers, Christoph M., Choi, Eun-Jung, Sharma, Preety M., Uduman, Mohamed, Li, Hong, Rux, Ann H., Farber, Sara A., Rubin, Courtney B., Kleinstein, Steven H., Sachais, Bruce S., Posner, Marshall R., Cavacini, Lisa A., Payne, Aimee S.
Published in Nature communications (19.06.2014)
Published in Nature communications (19.06.2014)
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Persistence of long-lived plasma cells and humoral immunity in individuals responding to CD19-directed CAR T-cell therapy
Bhoj, Vijay G., Arhontoulis, Dimitrios, Wertheim, Gerald, Capobianchi, James, Callahan, Colleen A., Ellebrecht, Christoph T., Obstfeld, Amrom E., Lacey, Simon F., Melenhorst, Jan J., Nazimuddin, Farzana, Hwang, Wei-Ting, Maude, Shannon L., Wasik, Mariusz A., Bagg, Adam, Schuster, Stephen, Feldman, Michael D., Porter, David L., Grupp, Stephen A., June, Carl H., Milone, Michael C.
Published in Blood (21.07.2016)
Published in Blood (21.07.2016)
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On the mark: genetically engineered immunotherapies for autoimmunity
Ellebrecht, Christoph T, Lundgren, Daniel K, Payne, Aimee S
Published in Current opinion in immunology (01.12.2019)
Published in Current opinion in immunology (01.12.2019)
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National Psoriasis Foundation COVID-19 Task Force guidance for management of psoriatic disease during the pandemic: Version 2—Advances in psoriatic disease management, COVID-19 vaccines, and COVID-19 treatments
Gelfand, Joel M., Armstrong, April W., Bell, Stacie, Anesi, George L., Blauvelt, Andrew, Calabrese, Cassandra, Dommasch, Erica D., Feldman, Steven R., Gladman, Dafna, Kircik, Leon, Lebwohl, Mark, Lo Re, Vincent, Martin, George, Merola, Joseph F., Scher, Jose U., Schwartzman, Sergio, Treat, James R., Van Voorhees, Abby S., Ellebrecht, Christoph T., Fenner, Justine, Ocon, Anthony, Syed, Maha N., Weinstein, Erica J., Gondo, George, Heydon, Sue, Koons, Samantha, Ritchlin, Christopher T.
Published in Journal of the American Academy of Dermatology (01.05.2021)
Published in Journal of the American Academy of Dermatology (01.05.2021)
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Lichen‐planus‐pemphigoides‐like reaction to PD‐1 checkpoint blockade
Wat, Margaret, Mollanazar, Nicholas K., Ellebrecht, Christoph T., Forrestel, Amy, Elenitsas, Rosalie, Chu, Emily Y.
Published in Journal of cutaneous pathology (01.11.2022)
Published in Journal of cutaneous pathology (01.11.2022)
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Fate induction in CD8 CAR T cells through asymmetric cell division
Lee, Casey S., Chen, Sisi, Berry, Corbett T., Kelly, Andre R., Herman, Patrick J., Oh, Sangwook, O’Connor, Roddy S., Payne, Aimee S., Ellebrecht, Christoph T.
Published in Nature (London) (19.09.2024)
Published in Nature (London) (19.09.2024)
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The dual nature of interleukin-10 in pemphigus vulgaris
Cho, Michael Jeffrey, Ellebrecht, Christoph T., Payne, Aimee S.
Published in Cytokine (Philadelphia, Pa.) (01.06.2015)
Published in Cytokine (Philadelphia, Pa.) (01.06.2015)
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Journal Article
National Psoriasis Foundation COVID-19 Task Force Guidance for Management of Psoriatic Disease During the Pandemic: Version 1
Gelfand, Joel M., Armstrong, April W., Bell, Stacie, Anesi, George L., Blauvelt, Andrew, Calabrese, Cassandra, Dommasch, Erica D., Feldman, Steve R., Gladman, Dafna, Kircik, Leon, Lebwohl, Mark, Lo Re, Vincent, Martin, George, Merola, Joseph F., Scher, Jose U., Schwartzman, Sergio, Treat, James R., Van Voorhees, Abby S., Ellebrecht, Christoph T., Fenner, Justine, Ocon, Anthony, Syed, Maha N., Weinstein, Erica J., Smith, Jessica, Gondo, George, Heydon, Sue, Koons, Samantha, Ritchlin, Christopher T.
Published in Journal of the American Academy of Dermatology (01.12.2020)
Published in Journal of the American Academy of Dermatology (01.12.2020)
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Vaccination recommendations for adults receiving biologics and oral therapies for psoriasis and psoriatic arthritis: Delphi consensus from the medical board of the National Psoriasis Foundation
Chat, Vipawee S, Ellebrecht, Christoph T, Kingston, Paige, Gondo, George, Bell, Stacie, Cordoro, Kelly M, Desai, Seemal R, Duffin, Kristina C, Feldman, Steven R, Garg, Amit, Gelfand, Joel M, Gladman, Dafna, Green, Lawrence J, Gudjonsson, Johann, Han, George, Hawkes, Jason E, Kircik, Leon, Koo, John, Langley, Richard, Lebwohl, Mark, Michael Lewitt, G, Liao, Wilson, Martin, George, Orbai, Ana-Maria, Reddy, Soumya M, Richardson, Veronica, Ritchlin, Christopher T, Schwartzman, Sergio, Siegel, Evan L, Van Voorhees, Abby S, Wallace, Elizabeth B, Weinberg, Jeffrey M, Winthrop, Kevin L, Yamauchi, Paul, Armstrong, April W
Published in Journal of the American Academy of Dermatology (01.06.2024)
Published in Journal of the American Academy of Dermatology (01.06.2024)
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Journal Article
Proteomic Analysis of Pemphigus Autoantibodies Indicates a Larger, More Diverse, and More Dynamic Repertoire than Determined by B Cell Genetics
Chen, Jing, Zheng, Qi, Hammers, Christoph M., Ellebrecht, Christoph T., Mukherjee, Eric M., Tang, Hsin-Yao, Lin, Chenyan, Yuan, Huijie, Pan, Meng, Langenhan, Jana, Komorowski, Lars, Siegel, Don L., Payne, Aimee S., Stanley, John R.
Published in Cell reports (Cambridge) (03.01.2017)
Published in Cell reports (Cambridge) (03.01.2017)
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