Agonist of Toll-Like Receptor 5 Has Radioprotective Activity in Mouse and Primate Models
Burdelya, Lyudmila G, Krivokrysenko, Vadim I, Tallant, Thomas C, Strom, Evguenia, Gleiberman, Anatoly S, Gupta, Damodar, Kurnasov, Oleg V, Fort, Farrel L, Osterman, Andrei L, DiDonato, Joseph A, Feinstein, Elena, Gudkov, Andrei V
Published in Science (American Association for the Advancement of Science) (11.04.2008)
Published in Science (American Association for the Advancement of Science) (11.04.2008)
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RNAi-Mediated Silencing of Nuclear Factor Erythroid-2-Related Factor 2 Gene Expression in Non-Small Cell Lung Cancer Inhibits Tumor Growth and Increases Efficacy of Chemotherapy
SINGH, Anju, BOLDIN-ADAMSKY, Swetlana, GABRIELSON, Edward, FEINSTEIN, Elena, BISWAL, Shyam, THIMMULAPPA, Rajesh K, RATH, Srikanta K, ASHUSH, Hagit, COULTER, Jonathan, BLACKFORD, Amanda, GOODMAN, Steven N, BUNZ, Fred, WATSON, Walter H
Published in Cancer research (Chicago, Ill.) (01.10.2008)
Published in Cancer research (Chicago, Ill.) (01.10.2008)
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Sestrin2 inhibits uncoupling protein 1 expression through suppressing reactive oxygen species
Ro, Seung-Hyun, Nam, Myeongjin, Jang, Insook, Park, Hwan-Woo, Park, Haeli, Semple, Ian A., Kim, Myungjin, Kim, Jeong Sig, Park, Haewon, Einat, Paz, Damari, Golda, Golikov, Maya, Feinstein, Elena, Lee, Jun Hee
Published in Proceedings of the National Academy of Sciences - PNAS (27.05.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (27.05.2014)
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Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema
Chukwueke, Ugonma, Bowman, Joel, Cosgrove, Gregory, Petrache, Irina, Shapiro, Steven D, Thimmulappa, Rajesh K, Mao, Tianzhi, Zhen, Lijie, Richter, Amy, Tuder, Rubin M, Mett, Igor, Sussan, Thomas, Zhang, Li, Brown, Emile, Bhunia, Anil K, Notkin, Natalie, Yoshida, Toshinori, Mouded, Majd, Gelfand, Anna, Perez, Mario, Ashush, Hagit, Gandjeva, Aneta, Biswal, Shyam, Feinstein, Elena, Rangasamy, Tirumalai
Published in Nature medicine (01.07.2010)
Published in Nature medicine (01.07.2010)
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Journal Article
siRNA-Mediated Knockdown of the mTOR Inhibitor RTP801 Promotes Retinal Ganglion Cell Survival and Axon Elongation by Direct and Indirect Mechanisms
Morgan-Warren, Peter J, O'Neill, Jenna, de Cogan, Felicity, Spivak, Igor, Ashush, Hagit, Kalinski, Hagar, Ahmed, Zubair, Berry, Martin, Feinstein, Elena, Scott, Robert A H, Logan, Ann
Published in Investigative ophthalmology & visual science (01.02.2016)
Published in Investigative ophthalmology & visual science (01.02.2016)
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Journal Article
Toll-like Receptor 5 Agonist Protects Mice From Dermatitis and Oral Mucositis Caused by Local Radiation: Implications for Head-and-Neck Cancer Radiotherapy
Burdelya, Lyudmila G., Ph.D, Gleiberman, Anatoli S., Ph.D, Toshkov, Ilia, M.D., Ph.D, Aygun-Sunar, Semra, Ph.D, Bapardekar, Meghana, Ph.D, Manderscheid-Kern, Patricia, Ph.D, Bellnier, David, Ph.D, Krivokrysenko, Vadim I., Ph.D, Feinstein, Elena, M.D., Ph.D, Gudkov, Andrei V., Ph.D., D.Sci
Published in International journal of radiation oncology, biology, physics (01.05.2012)
Published in International journal of radiation oncology, biology, physics (01.05.2012)
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Journal Article
Altered nutrient response of mTORC1 as a result of changes in REDD1 expression: effect of obesity vs. REDD1 deficiency
Williamson, David L, Li, Zhuyun, Tuder, Rubin M, Feinstein, Elena, Kimball, Scot R, Dungan, Cory M
Published in Journal of applied physiology (1985) (01.08.2014)
Published in Journal of applied physiology (1985) (01.08.2014)
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DDIT4/REDD1/RTP801 is a novel negative regulator of Schwann cell myelination
Noseda, Roberta, Belin, Sophie, Piguet, Françoise, Vaccari, Ilaria, Scarlino, Stefania, Brambilla, Paola, Martinelli Boneschi, Filippo, Feltri, Maria Laura, Wrabetz, Lawrence, Quattrini, Angelo, Feinstein, Elena, Huganir, Richard L, Bolino, Alessandra
Published in The Journal of neuroscience (18.09.2013)
Published in The Journal of neuroscience (18.09.2013)
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Journal Article
The Toll-Like Receptor 5 Agonist Entolimod Mitigates Lethal Acute Radiation Syndrome in Non-Human Primates
Krivokrysenko, Vadim I, Toshkov, Ilia A, Gleiberman, Anatoli S, Krasnov, Peter, Shyshynova, Inna, Bespalov, Ivan, Maitra, Ratan K, Narizhneva, Natalya V, Singh, Vijay K, Whitnall, Mark H, Purmal, Andrei A, Shakhov, Alexander N, Gudkov, Andrei V, Feinstein, Elena
Published in PloS one (14.09.2015)
Published in PloS one (14.09.2015)
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Prevention and mitigation of acute radiation syndrome in mice by synthetic lipopeptide agonists of Toll-like receptor 2 (TLR2)
Shakhov, Alexander N, Singh, Vijay K, Bone, Frederick, Cheney, Alec, Kononov, Yevgeniy, Krasnov, Peter, Bratanova-Toshkova, Troitza K, Shakhova, Vera V, Young, Jason, Weil, Michael M, Panoskaltsis-Mortari, Angela, Orschell, Christie M, Baker, Patricia S, Gudkov, Andrei, Feinstein, Elena
Published in PloS one (27.03.2012)
Published in PloS one (27.03.2012)
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Identification of a Novel Hypoxia-Inducible Factor 1-Responsive Gene, RTP801, Involved in Apoptosis
Shoshani, Tzipora, Faerman, Alexander, Mett, Igor, Zelin, Elena, Tenne, Tamar, Gorodin, Svetlana, Moshel, Yana, Elbaz, Shlomo, Budanov, Andrei, Chajut, Ayelet, Kalinski, Hagar, Kamer, Iris, Rozen, Ada, Mor, Orna, Keshet, Eli, Leshkowitz, Dena, Einat, Paz, Skaliter, Rami, Feinstein, Elena
Published in Molecular and Cellular Biology (01.04.2002)
Published in Molecular and Cellular Biology (01.04.2002)
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Journal Article
p120 catenin regulates lamellipodial dynamics and cell adhesion in cooperation with cortactin
Boguslavsky, Shlomit, Grosheva, Inna, Landau, Elad, Shtutman, Michael, Cohen, Miriam, Arnold, Katya, Feinstein, Elena, Geiger, Benjamin, Bershadsky, Alexander
Published in Proceedings of the National Academy of Sciences - PNAS (26.06.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (26.06.2007)
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Journal Article
p53 is a suppressor of inflammatory response in mice
Komarova, Elena A, Krivokrysenko, Vadim, Wang, Kaihua, Neznanov, Nickolay, Chernov, Mikhail V, Komarov, Pavel G, Brennan, Marie-Luise, Golovkina, Tatiana V, Rokhlin, Oskar W, Kuprash, Dmitry V, Nedospasov, Sergei A, Hazen, Stanley L, Feinstein, Elena, Gudkov, Andrei V
Published in The FASEB journal (01.06.2005)
Published in The FASEB journal (01.06.2005)
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Delayed intrathecal delivery of RhoA siRNA to the contused spinal cord inhibits allodynia, preserves white matter, and increases serotonergic fiber growth
Otsuka, Seiji, Adamson, Crista, Sankar, Venkatachalam, Gibbs, Kurt M, Kane-Goldsmith, Noriko, Ayer, Jennie, Babiarz, Joanne, Kalinski, Hagar, Ashush, Hagit, Alpert, Evgenia, Lahav, Ron, Feinstein, Elena, Grumet, Martin
Published in Journal of neurotrauma (01.06.2011)
Published in Journal of neurotrauma (01.06.2011)
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Journal Article
Intravital Two-Photon Microscopy Assessment of Renal Protection Efficacy of siRNA for p53 in Experimental Rat Kidney Transplantation Models
Imamura, Ryoichi, Isaka, Yoshitaka, Sandoval, Ruben M., Ori, Asaf, Adamsky, Swetlana, Feinstein, Elena, Molitoris, Bruce A., Takahara, Shiro
Published in Cell transplantation (01.12.2010)
Published in Cell transplantation (01.12.2010)
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Journal Article
DAP-kinase loss of expression in various carcinoma and B-cell lymphoma cell lines : possible implications for role as tumor suppressor gene
KISSIL, J. L, FEINSTEIN, E, COHEN, O, JONES, P. A, TSAI, Y. C, KNOWLES, M. A, EYDMANN, M. E, KIMCHI, A
Published in Oncogene (24.07.1997)
Published in Oncogene (24.07.1997)
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Stress-induced secretion of growth inhibitors : a novel tumor suppressor function of p53
KOMAROVA, E. A, DIATCHENKO, L, ROKHLIN, O. W, HILL, J. E, WANG, Z. J, KRIVOKRYSENKO, V. I, FEINSTEIN, E, GUDKOV, A. V
Published in Oncogene (03.09.1998)
Published in Oncogene (03.09.1998)
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Studies on the Transcriptional Regulation of Cholesterol 24-Hydroxylase (CYP46A1)
Ohyama, Yoshihiko, Meaney, Steve, Heverin, Maura, Ekström, Lena, Brafman, Anat, Shafir, Millicent, Andersson, Ulla, Olin, Maria, Eggertsen, Gösta, Diczfalusy, Ulf, Feinstein, Elena, Björkhem, Ingemar
Published in The Journal of biological chemistry (17.02.2006)
Published in The Journal of biological chemistry (17.02.2006)
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siRNA Targeted to p53 Attenuates Ischemic and Cisplatin-Induced Acute Kidney Injury
MOLITORIS, Bruce A, DAGHER, Pierre C, KALINSKI, Hagar, SKALITER, Rami, ERLICH, Shai, FEINSTEIN, Elena, SANDOVAL, Ruben M, CAMPOS, Silvia B, ASHUSH, Hagit, FRIDMAN, Eduard, BRAFMAN, Anat, FAERMAN, Alexander, ATKINSON, Simon J, THOMPSON, James D
Published in Journal of the American Society of Nephrology (01.08.2009)
Published in Journal of the American Society of Nephrology (01.08.2009)
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