An oral antisense oligonucleotide for PCSK9 inhibition
Gennemark, Peter, Walter, Katrin, Clemmensen, Niclas, Rekić, Dinko, Nilsson, Catarina A M, Knöchel, Jane, Hölttä, Mikko, Wernevik, Linda, Rosengren, Birgitta, Kakol-Palm, Dorota, Wang, Yanfeng, Yu, Rosie Z, Geary, Richard S, Riney, Stan J, Monia, Brett P, Isaksson, Rikard, Jansson-Löfmark, Rasmus, Rocha, Cristina S J, Lindén, Daniel, Hurt-Camejo, Eva, Crooke, Rosanne, Tillman, Lloyd, Rydén-Bergsten, Tina, Carlsson, Björn, Andersson, Ulf, Elebring, Marie, Tivesten, Anna, Davies, Nigel
Published in Science translational medicine (12.05.2021)
Published in Science translational medicine (12.05.2021)
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Multiple compound-related adverse properties contribute to liver injury caused by endothelin receptor antagonists
Kenna, J Gerry, Stahl, Simone H, Eakins, Julie A, Foster, Alison J, Andersson, Linda C, Bergare, Jonas, Billger, Martin, Elebring, Marie, Elmore, Charles S, Thompson, Richard A
Published in The Journal of pharmacology and experimental therapeutics (01.02.2015)
Published in The Journal of pharmacology and experimental therapeutics (01.02.2015)
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Abstract 13307: An Oral Antisense Oligonucleotide for PCSK9 Inhibition in Humans
Gennemark, Peter, Walter, Katrin, Clemmensen, Niclas, Rekic, Dinko, Nilsson, Catarina, Knoechel, Jane, Holtta, Mikko, Wang, Yanfeng, Yu, Rosie, riney, stanley, Monia, Brett P, Andersson, Ulf, Jansson-Lofmark, Rasmus, Rocha, Cristina S, Linden, Daniel, Ryden-Bergsten, Kristina, Hurt-Camejo, Eva, CROOKE, Rosanne M, Tillman, Lloyd, Carlsson, Bjorn, Elebring, Marie, Tivesten, Anna, Davies, Nigel
Published in Circulation (New York, N.Y.) (17.11.2020)
Published in Circulation (New York, N.Y.) (17.11.2020)
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In Vivo Metabolite Profiles of an N -Acetylgalactosamine–Conjugated Antisense Oligonucleotide AZD8233 Using Liquid Chromatography High-Resolution Mass Spectrometry: A Cross-Species Comparison in Animals and Humans
Li, Xue-Qing, Elebring, Marie, Dahlén, Anders, Weidolf, Lars
Published in Drug metabolism and disposition (01.10.2023)
Published in Drug metabolism and disposition (01.10.2023)
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In Vivo Metabolite Profiles of a GalNAc Conjugated Antisense Oligonucleotide AZD8233 Using Liquid Chromatography-High Resolution Mass Spectrometry: a Cross Species Comparison in Animals and Humans
Li, Xue-Qing, Elebring, Marie, Dahlén, Anders, Weidolf, Lars
Published in Drug metabolism and disposition (10.07.2023)
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Published in Drug metabolism and disposition (10.07.2023)
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Understanding Statin‐Roxadustat Drug–Drug‐Disease Interaction Using Physiologically‐Based Pharmacokinetic Modeling
Dong, Jin, Prieto Garcia, Luna, Huang, Yingbo, Tang, Weifeng, Lundahl, Anna, Elebring, Marie, Ahlström, Christine, Vildhede, Anna, Sjögren, Erik, Någård, Mats
Published in Clinical pharmacology and therapeutics (01.10.2023)
Published in Clinical pharmacology and therapeutics (01.10.2023)
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Distribution and biotransformation of therapeutic antisense oligonucleotides and conjugates
Weidolf, Lars, Björkbom, Anders, Dahlén, Anders, Elebring, Marie, Gennemark, Peter, Hölttä, Mikko, Janzén, David, Li, XueQing, Andersson, Shalini
Published in Drug discovery today (01.10.2021)
Published in Drug discovery today (01.10.2021)
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Corrigendum to ‘Drug metabolism and pharmacokinetic strategies for oligonucleotide- and mRNA-based drug development’ Drug Discovery Today 23 (2018) 1733–1745
Andersson, Shalini, Antonsson, Madeleine, Elebring, Marie, Jansson-Löfmark, Rasmus, Weidolf, Lars
Published in Drug discovery today (01.09.2019)
Published in Drug discovery today (01.09.2019)
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Injectable Biodegradable Silica Depot for Controlled Subcutaneous Delivery of Antisense Oligonucleotides with beyond Monthly Administration
McGowan, Asmaa, Gennemark, Peter, Akieh-Pirkanniemi, Marceline, Wirman, Linda, Davies, Nigel, Elebring, Marie, Tivesten, Anna, Strimfors, Marie, Hölttä, Mikko, Söderberg, Magnus, Berntsson, Veronica, Balas, Daniela, Koskinen, Mika, Leino, Lasse, Abrahmsén-Alami, Susanna
Published in Molecular pharmaceutics (01.01.2024)
Published in Molecular pharmaceutics (01.01.2024)
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경구 투여용 안티센스 올리고뉴클레오티드를 포함하는 약학적 조성물
RADEVIK ANDREAS, CLEMMENSEN NICLAS, WALTER KATRIN, ELEBRING MARIE, TIVESTEN ANNA, GENNEMARK PETER, MATIC HANNA, MARUCCI MARIAGRAZIA, PUTRA OKKY, TILLMAN LLOYD, DAVIES NIGEL, UPADHYAY PRATIK PANKAJ, DELLAMARY LUIS
Year of Publication 18.05.2023
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Year of Publication 18.05.2023
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Effect of broad-spectrum matrix metalloproteinase inhibition on atherosclerotic plaque stability
JOHNSON, Jason L, FRITSCHE-DANIELSON, Regina, BEHRENDT, Margareta, WESTIN-ERIKSSON, Annika, WENNBO, Hakan, HERSLOF, Margareta, ELEBRING, Marie, GEORGE, Sarah J, MCPHEAT, William L, JACKSON, Christopher L
Published in Cardiovascular research (01.08.2006)
Published in Cardiovascular research (01.08.2006)
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Abstract 11146: AZD3366-an Optimized Recombinant Human Apyrase Combining Anti Platelet, Anti Inflammatory and Tissue Protective Actions With Low Bleeding Risk for Potential Mitigation of Thromboembolic Complications
Pehrsson, Susanne, Kull, Bengt, Hovdal, Daniel, Elebring, Marie, Whatling, Carl, Fjellstrom, Ola, Carlsson, Leif
Published in Circulation (New York, N.Y.) (19.11.2019)
Published in Circulation (New York, N.Y.) (19.11.2019)
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Tesaglitazar, a PPARα/γ Agonist, Induces Interstitial Mesenchymal Cell DNA Synthesis and Fibrosarcomas in Subcutaneous Tissues in Rats
Hellmold, Heike, Zhang, Hui, Andersson, Ulf, Blomgren, Bo, Holland, Tom, Berg, Anna-Lena, Elebring, Marie, Sjögren, Niclas, Bamberg, Krister, Dahl, Björn, Westerberg, Rolf, Dillner, Birgitta, Tugwood, Jonathan, Roberts, Ruth, Lundholm, Erik, Camejo, German, Skånberg, Inger, Evans, John
Published in Toxicological sciences (01.07.2007)
Published in Toxicological sciences (01.07.2007)
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Tesaglitazar, a PPARalpha/gamma agonist, induces interstitial mesenchymal cell DNA synthesis and fibrosarcomas in subcutaneous tissues in rats
Hellmold, Heike, Zhang, Hui, Andersson, Ulf, Blomgren, Bo, Holland, Tom, Berg, Anna-Lena, Elebring, Marie, Sjögren, Niclas, Bamberg, Krister, Dahl, Björn, Westerberg, Rolf, Dillner, Birgitta, Tugwood, Jonathan, Roberts, Ruth, Lundholm, Erik, Camejo, German, Skånberg, Inger, Evans, John
Published in Toxicological sciences (01.07.2007)
Published in Toxicological sciences (01.07.2007)
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PHARMACEUTICAL COMPOSITIONS COMPRISING AN ANTISENSE OLIGONUCLEOTIDE FOR ORAL ADMINISTRATION
CLEMMENSEN, Niclas, MARUCCI, Mariagrazia, WALTER, Katrin, PUTRA, Okky, UPADHYAY, Pratik Pankaj, RÅDEVIK, Andreas, TILLMAN, Lloyd, DELLAMARY, Luis, DAVIES, Nigel, MATIC, Hanna, GENNEMARK, Peter, TIVESTEN, Anna, ELEBRING, Marie
Year of Publication 09.11.2023
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Year of Publication 09.11.2023
Patent
PHARMACEUTICAL COMPOSITIONS COMPRISING AN ANTISENSE OLIGONUCLEOTIDE FOR ORAL ADMINISTRATION
CLEMMENSEN, Niclas, MARUCCI, Mariagrazia, WALTER, Katrin, PUTRA, Okky, UPADHYAY, Pratik Pankaj, RÅDEVIK, Andreas, TILLMAN, Lloyd, DELLAMARY, Luis, DAVIES, Nigel, MATIC, Hanna, GENNEMARK, Peter, TIVESTEN, Anna, ELEBRING, Marie
Year of Publication 26.07.2023
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Year of Publication 26.07.2023
Patent
PHARMACEUTICAL COMPOSITIONS COMPRISING AN ANTISENSE OLIGONUCLEOTIDE FOR ORAL ADMINISTRATION
CLEMMENSEN, Niclas, MARUCCI, Mariagrazia, WALTER, Katrin, PUTRA, Okky, UPADHYAY, Pratik Pankaj, RÅDEVIK, Andreas, TILLMAN, Lloyd, DELLAMARY, Luis, DAVIES, Nigel, MATIC, Hanna, GENNEMARK, Peter, TIVESTEN, Anna, ELEBRING, Marie
Year of Publication 18.05.2023
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Year of Publication 18.05.2023
Patent
PHARMACEUTICAL COMPOSITIONS COMPRISING AN ANTISENSE OLIGONUCLEOTIDE FOR ORAL ADMINISTRATION
GENNEMARK, PETER, TIVESTEN, ANNA, CLEMMENSEN, NICLAS, WALTER, KATRIN, PUTRA, OKKY, MATIC, HANNA, ELEBRING, MARIE, UPADHYAY, PRATIK PANKAJ, RADEVIK, ANDREAS, TILLMAN, LLOYD, DELLAMARY, LUIS, DAVIES, NIGEL, MARUCCI, MARIAGRAZIA
Year of Publication 24.03.2022
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Year of Publication 24.03.2022
Patent