Extracellular adenosine reversibly inhibits the activation of human regulatory T cells and negatively influences the achievement of the operational tolerance in liver transplantation
Baroja‐Mazo, Alberto, Revilla‐Nuin, Beatriz, Bejar, África, Martínez‐Alarcón, Laura, Herrero, José I., El‐Tayeb, Ali, Müller, Christa E., Aparicio, Pedro, Pelegrín, Pablo, Pons, José A.
Published in American journal of transplantation (01.01.2019)
Published in American journal of transplantation (01.01.2019)
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Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors
Gnad, Thorsten, Scheibler, Saskia, von Kügelgen, Ivar, Scheele, Camilla, Kilić, Ana, Glöde, Anja, Hoffmann, Linda S., Reverte-Salisa, Laia, Horn, Philipp, Mutlu, Samet, El-Tayeb, Ali, Kranz, Mathias, Deuther-Conrad, Winnie, Brust, Peter, Lidell, Martin E., Betz, Matthias J., Enerbäck, Sven, Schrader, Jürgen, Yegutkin, Gennady G., Müller, Christa E., Pfeifer, Alexander
Published in Nature (London) (18.12.2014)
Published in Nature (London) (18.12.2014)
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N‑Substituted Phenoxazine and Acridone Derivatives: Structure–Activity Relationships of Potent P2X4 Receptor Antagonists
Hernandez-Olmos, Victor, Abdelrahman, Aliaa, El-Tayeb, Ali, Freudendahl, Diana, Weinhausen, Stephanie, Müller, Christa E
Published in Journal of medicinal chemistry (26.11.2012)
Published in Journal of medicinal chemistry (26.11.2012)
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Characterization of P2X4 receptor agonists and antagonists by calcium influx and radioligand binding studies
Abdelrahman, Aliaa, Namasivayam, Vigneshwaran, Hinz, Sonja, Schiedel, Anke C., Köse, Meryem, Burton, Maggi, El-Tayeb, Ali, Gillard, Michel, Bajorath, Jürgen, de Ryck, Marc, Müller, Christa E.
Published in Biochemical pharmacology (01.02.2017)
Published in Biochemical pharmacology (01.02.2017)
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X‐Ray Co‐Crystal Structure Guides the Way to Subnanomolar Competitive Ecto‐5′‐Nucleotidase (CD73) Inhibitors for Cancer Immunotherapy
Bhattarai, Sanjay, Pippel, Jan, Meyer, Anne, Freundlieb, Marianne, Schmies, Constanze, Abdelrahman, Aliaa, Fiene, Amelie, Lee, Sang‐Yong, Zimmermann, Herbert, El‐Tayeb, Ali, Yegutkin, Gennady G., Sträter, Norbert, Müller, Christa E.
Published in Advanced therapeutics (01.10.2019)
Published in Advanced therapeutics (01.10.2019)
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Journal Article
Adenosine A2A receptor agonists with potent antiplatelet activity
Fuentes, Eduardo, Fuentes, Manuel, Caballero, Julio, Palomo, Iván, Hinz, Sonja, El-Tayeb, Ali, Müller, Christa E
Published in Platelets (Edinburgh) (01.05.2018)
Published in Platelets (Edinburgh) (01.05.2018)
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α,β-Methylene-ADP (AOPCP) Derivatives and Analogues: Development of Potent and Selective ecto-5′-Nucleotidase (CD73) Inhibitors
Bhattarai, Sanjay, Freundlieb, Marianne, Pippel, Jan, Meyer, Anne, Abdelrahman, Aliaa, Fiene, Amelie, Lee, Sang-Yong, Zimmermann, Herbert, Yegutkin, Gennady G, Sträter, Norbert, El-Tayeb, Ali, Müller, Christa E
Published in Journal of medicinal chemistry (13.08.2015)
Published in Journal of medicinal chemistry (13.08.2015)
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2‑Substituted α,β-Methylene-ADP Derivatives: Potent Competitive Ecto-5′-nucleotidase (CD73) Inhibitors with Variable Binding Modes
Bhattarai, Sanjay, Pippel, Jan, Scaletti, Emma, Idris, Riham, Freundlieb, Marianne, Rolshoven, Georg, Renn, Christian, Lee, Sang-Yong, Abdelrahman, Aliaa, Zimmermann, Herbert, El-Tayeb, Ali, Müller, Christa E, Sträter, Norbert
Published in Journal of medicinal chemistry (26.03.2020)
Published in Journal of medicinal chemistry (26.03.2020)
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Journal Article
A2A and A2B adenosine receptors: The extracellular loop 2 determines high (A2A) or low affinity (A2B) for adenosine
De Filippo, Elisabetta, Hinz, Sonja, Pellizzari, Veronica, Deganutti, Giuseppe, El-Tayeb, Ali, Navarro, Gemma, Franco, Rafael, Moro, Stefano, Schiedel, Anke C., Müller, Christa E.
Published in Biochemical pharmacology (01.02.2020)
Published in Biochemical pharmacology (01.02.2020)
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Journal Article
Correction to: Preparation and preliminary evaluation of a tritium-labeled allosteric P2X4 receptor antagonist
Nagel, Jessica, Törmäkangas, Olli, Kuokkanen, Katja, El-Tayeb, Ali, Messinger, Josef, Abdelrahman, Aliaa, Bous, Christiane, Schiedel, Anke C, Müller, Christa E
Published in Purinergic signalling (19.06.2024)
Published in Purinergic signalling (19.06.2024)
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Journal Article
Ecto-5'-nucleotidase (CD73)-mediated formation of adenosine is critical for the striatal adenosine A2A receptor functions
Augusto, Elisabete, Matos, Marco, Sévigny, Jean, El-Tayeb, Ali, Bynoe, Margaret S, Müller, Christa E, Cunha, Rodrigo A, Chen, Jiang-Fan
Published in The Journal of neuroscience (10.07.2013)
Published in The Journal of neuroscience (10.07.2013)
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Journal Article
Preparation and preliminary evaluation of a tritium-labeled allosteric P2X4 receptor antagonist
Nagel, Jessica, Törmäkangas, Olli, Kuokkanen, Katja, El-Tayeb, Ali, Messinger, Josef, Abdelrahman, Aliaa, Bous, Christiane, Schiedel, Anke C, Müller, Christa E
Published in Purinergic signalling (25.05.2024)
Published in Purinergic signalling (25.05.2024)
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Journal Article
Substituted 4-phenylthiazoles: Development of potent and selective A1, A3 and dual A1/A3 adenosine receptor antagonists
Abdelrahman, Aliaa, Yerande, Swapnil G., Namasivayam, Vigneshwaran, Klapschinski, Tim A., Alnouri, Mohamad Wessam, El-Tayeb, Ali, Müller, Christa E.
Published in European journal of medicinal chemistry (15.01.2020)
Published in European journal of medicinal chemistry (15.01.2020)
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Journal Article
Carbamazepine derivatives with P2X4 receptor-blocking activity
Tian, Maoqun, Abdelrahman, Aliaa, Weinhausen, Stephanie, Hinz, Sonja, Weyer, Stefanie, Dosa, Stefan, El-Tayeb, Ali, Müller, Christa E.
Published in Bioorganic & medicinal chemistry (01.02.2014)
Published in Bioorganic & medicinal chemistry (01.02.2014)
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