The position of single-base deletions in the VNTR sequence of the carboxyl ester lipase (CEL) gene determines proteotoxicity
Gravdal, Anny, Xiao, Xunjun, Cnop, Miriam, El Jellas, Khadija, Johansson, Stefan, Njølstad, Pål R., Lowe, Mark E., Johansson, Bente B., Molven, Anders, Fjeld, Karianne
Published in The Journal of biological chemistry (01.01.2021)
Published in The Journal of biological chemistry (01.01.2021)
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Journal Article
Two New Mutations in the CEL Gene Causing Diabetes and Hereditary Pancreatitis: How to Correctly Identify MODY8 Cases
El Jellas, Khadija, Dušátková, Petra, Haldorsen, Ingfrid S, Molnes, Janne, Tjora, Erling, Johansson, Bente B, Fjeld, Karianne, Johansson, Stefan, Průhová, Štěpánka, Groop, Leif, Löhr, J Matthias, Njølstad, Pål R, Molven, Anders
Published in The journal of clinical endocrinology and metabolism (01.04.2022)
Published in The journal of clinical endocrinology and metabolism (01.04.2022)
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Journal Article
The role of the carboxyl ester lipase (CEL) gene in pancreatic disease
Johansson, Bente B., Fjeld, Karianne, El Jellas, Khadija, Gravdal, Anny, Dalva, Monica, Tjora, Erling, Ræder, Helge, Kulkarni, Rohit N., Johansson, Stefan, Njølstad, Pål R., Molven, Anders
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.01.2018)
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.01.2018)
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Journal Article
The mucinous domain of pancreatic carboxyl-ester lipase (CEL) contains core 1/core 2 O-glycans that can be modified by ABO blood group determinants
El Jellas, Khadija, Johansson, Bente B., Fjeld, Karianne, Antonopoulos, Aristotelis, Immervoll, Heike, Choi, Man H., Hoem, Dag, Lowe, Mark E., Lombardo, Dominique, Njølstad, Pål R., Dell, Anne, Mas, Eric, Haslam, Stuart M., Molven, Anders
Published in The Journal of biological chemistry (14.12.2018)
Published in The Journal of biological chemistry (14.12.2018)
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Journal Article
The genetic risk factor CEL-HYB1 causes proteotoxicity and chronic pancreatitis in mice
Fjeld, Karianne, Gravdal, Anny, Brekke, Ranveig S., Alam, Jahedul, Wilhelm, Steven J., El Jellas, Khadija, Pettersen, Helene N., Lin, Jianguo, Solheim, Marie H., Steine, Solrun J., Johansson, Bente B., Njølstad, Pål R., Verbeke, Caroline S., Xiao, Xunjun, Lowe, Mark E., Molven, Anders
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.12.2022)
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.12.2022)
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Journal Article
Mutation analysis by deep sequencing of pancreatic juice from patients with pancreatic ductal adenocarcinoma
Choi, Man Hung, Mejlænder-Andersen, Eline, Manueldas, Sophia, El Jellas, Khadija, Steine, Solrun J, Tjensvoll, Kjersti, Sætran, Hege Aase, Knappskog, Stian, Hoem, Dag, Nordgård, Oddmund, Hovland, Randi, Molven, Anders
Published in BMC cancer (05.01.2019)
Published in BMC cancer (05.01.2019)
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Journal Article
Altered O- and N-linked glycosylation profiles in carboxyl ester lipase (CEL) protein variants involved in chronic pancreatitis and MODY8 syndrome
El Jellas, Khadija, Haslam, Stuart M., Choi, Man Hung, Dell, Anne, Johansson, Bente B., Fjeld, Karianne, Molven, Anders
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.06.2018)
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.06.2018)
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Journal Article
Aberrant N- and O-linked glycosylation in carboxyl ester lipase (CEL) protein variants involved in MODY8 syndrome and chronic pancreatitis
El Jellas, Khadija, Antonopoulos, Aristotelis, Haslam, Stuart M., Choi, Man H., Dell, Anne, Njølstad, Pål. R, Johansson, Bente Berg, Fjeld, Karianne, Molven, Anders
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.06.2019)
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.06.2019)
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Journal Article
Copy number variants and VNTR length polymorphisms of the carboxyl-ester lipase ( CEL ) gene as risk factors in pancreatic cancer
Dalva, Monica, El Jellas, Khadija, Steine, Solrun J, Johansson, Bente B, Ringdal, Monika, Torsvik, Janniche, Immervoll, Heike, Hoem, Dag, Laemmerhirt, Felix, Simon, Peter, Lerch, Markus M, Johansson, Stefan, Njølstad, Pål R, Weiss, Frank U, Fjeld, Karianne, Molven, Anders
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.01.2017)
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.01.2017)
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Journal Article
1557-P: Increased PAHSA Hydrolysis Driven by Mutant Carboxyl Ester Lipase (CEL) Contributes to Beta-Cell Dysfunction in MODY8
SANTORO, ANNA, KAHRAMAN, SEVIM, BASILE, GIORGIO, EL JELLAS, KHADIJA, HU, JIANG, TARPEY, RYAN, JOHANSSON, BENTE B., DIRICE, ERCUMENT, SYED, ISMAIL, SIEGEL, DIONICIO, MOLVEN, ANDERS, KAHN, BARBARA B., KULKARNI, ROHIT
Published in Diabetes (New York, N.Y.) (14.06.2024)
Published in Diabetes (New York, N.Y.) (14.06.2024)
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Journal Article
Characterization of CEL-DUP2: Complete duplication of the carboxyl ester lipase gene is unlikely to influence risk of chronic pancreatitis
Fjeld, Karianne, Masson, Emmanuelle, Lin, Jin-Huan, Michl, Patrick, Stokowy, Tomasz, Gravdal, Anny, El Jellas, Khadija, Steine, Solrun J., Hoem, Dag, Johansson, Bente B., Dalva, Monica, Ruffert, Claudia, Zou, Wen-Bin, Li, Zhao-Shen, Njølstad, Pål R., Chen, Jian-Min, Liao, Zhuan, Johansson, Stefan, Rosendahl, Jonas, Férec, Claude, Molven, Anders
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.04.2020)
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.04.2020)
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Journal Article
Different effects of frameshift mutations occurring in the repeat region of the pancreatic enzyme carboxyl ester lipase (CEL)
Gravdal, Anny, Brekke, Ranveig Seim, El Jellas, Khadija, Xiao, Xunjun, Lowe, Mark E., Lombardo, Dominique, Mas, Eric, Johansson, Bente Berg, Fjeld, Karianne, Molven, Anders
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.06.2018)
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.06.2018)
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Journal Article
Mutation analysis by deep sequencing of pancreatic juice in patients with pancreatic ductal adenocarcinoma
Choi, Man Hung, Mejlænder-Larsen, Eline, Manueldas, Sophia, El Jellas, Khadija, Steine, Solrun J., Tjensvoll, Kjersti, Sætran, Hege Aase, Knappskog, Stian, Hoem, Dag, Nordgård, Oddmund, Hovland, Randi, Molven, Anders
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.06.2018)
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.06.2018)
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Journal Article
Associations between ABO blood groups and pancreatic ductal adenocarcinoma: influence on resection status and survival
El Jellas, Khadija, Hoem, Dag, Hagen, Kristin G, Kalvenes, May Britt, Aziz, Sura, Steine, Solrun J, Immervoll, Heike, Johansson, Stefan, Molven, Anders
Published in Cancer medicine (Malden, MA) (01.07.2017)
Published in Cancer medicine (Malden, MA) (01.07.2017)
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Journal Article
Pancreatic carboxyl-ester lipase (CEL) can present ABO blood group determinants with potential implications for cancer cell recognition
El Jellas, Khadija, Immervoll, Heike, Steffensen, Ole, Johansson, Bente Berg, Fjeld, Karianne, Lombardo, Dominique, Njřlstad, Pĺl Rasmus, Mas, Eric, Molven, Anders
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.07.2017)
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.07.2017)
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Journal Article
The polymorphic carboxyl-ester lipase (CEL) gene: novel copy number variants (CNVs) identified by both classical and high-throughput genetic analysis
Fjeld, Karianne, Masson, Emmanuelle Masson, Michl, Patrick, Stokowy, Tomasz, Lin, He, Steine, Solrun J., Johansson, Bente B., Dalva, Monica, El Jellas, Khadija, Ruffert, Claudia, Zou, Wen-Bin, Li, Zhao-Shen, Njølstad, Pål R, Chen, Jian-Min, Liao, Zhuan, Johansson, Stefan, Rosendahl, Jonas, Férec, Claude, Molven, Anders
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.06.2018)
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.06.2018)
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Journal Article
Pathogenic Carboxyl Ester Lipase (CEL) Variants Interact with the Normal CEL Protein in Pancreatic Cells
Dalva, Monica, Lavik, Ida K, El Jellas, Khadija, Gravdal, Anny, Lugea, Aurelia, Pandol, Stephen J, Njølstad, Pål R, Waldron, Richard T, Fjeld, Karianne, Johansson, Bente B, Molven, Anders
Published in Cells (Basel, Switzerland) (18.01.2020)
Published in Cells (Basel, Switzerland) (18.01.2020)
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Journal Article
Carboxyl ester lipase (CEL) in pancreatic disease: pathogenicity of CEL-MODY, but not CEL-HYB1, depends on cysteine residues in the hypervariable tail region
Garzón, Miguel Juárez, El Jellas, Khadija, Navarsete, Rune H., Torsvik, Janniche, Reuther, Nathalie, Lowe, Mark E., Xiao, Xunjun, Fjeld, Karianne, Molven, Anders
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (05.11.2023)
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (05.11.2023)
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Journal Article
Common single-base insertions in the VNTR of the carboxyl ester lipase (CEL) gene are benign and also likely to arise somatically in the exocrine pancreas
Brekke, Ranveig S, Gravdal, Anny, El Jellas, Khadija, Curry, Grace E, Lin, Jianguo, Wilhelm, Steven J, Steine, Solrun J, Mas, Eric, Johansson, Stefan, Lowe, Mark E, Johansson, Bente B, Xiao, Xunjun, Fjeld, Karianne, Molven, Anders
Published in Human molecular genetics (18.05.2024)
Published in Human molecular genetics (18.05.2024)
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Journal Article
Deficiency of the metabolic enzyme SCHAD in pancreatic β-cells promotes amino acid–sensitive hypoglycemia
St-Louis, Johanna L., El Jellas, Khadija, Velasco, Kelly, Slipp, Brittany A., Hu, Jiang, Helgeland, Geir, Steine, Solrun J., De Jesus, Dario F., Kulkarni, Rohit N., Molven, Anders
Published in The Journal of biological chemistry (01.08.2023)
Published in The Journal of biological chemistry (01.08.2023)
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Journal Article