Isolated unilateral ptosis as a complication of sinusitis: A case report and literature review
El Sayed Ahmad, Youssef, Kazemizadeh Gol, Mohammad Abraham
Published in Clinical case reports (01.08.2024)
Published in Clinical case reports (01.08.2024)
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Journal Article
A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy
Ronan, Baptiste, Flamand, Odile, Vescovi, Lionel, Dureuil, Christine, Durand, Laurence, Fassy, Florence, Bachelot, Marie-France, Lamberton, Annabelle, Mathieu, Magali, Bertrand, Thomas, Marquette, Jean-Pierre, El-Ahmad, Youssef, Filoche-Romme, Bruno, Schio, Laurent, Garcia-Echeverria, Carlos, Goulaouic, Hélène, Pasquier, Benoit
Published in Nature chemical biology (01.12.2014)
Published in Nature chemical biology (01.12.2014)
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Discovery of (2S)‑8-[(3R)‑3-Methylmorpholin-4-yl]-1-(3-methyl-2-oxobutyl)-2-(trifluoromethyl)-3,4-dihydro‑2H‑pyrimido[1,2‑a]pyrimidin-6-one: A Novel Potent and Selective Inhibitor of Vps34 for the Treatment of Solid Tumors
Pasquier, Benoit, El-Ahmad, Youssef, Filoche-Rommé, Bruno, Dureuil, Christine, Fassy, Florence, Abecassis, Pierre-Yves, Mathieu, Magali, Bertrand, Thomas, Benard, Tsiala, Barrière, Cédric, El Batti, Samira, Letallec, Jean-Philippe, Sonnefraud, Véronique, Brollo, Maurice, Delbarre, Laurence, Loyau, Véronique, Pilorge, Fabienne, Bertin, Luc, Richepin, Patrick, Arigon, Jérôme, Labrosse, Jean-Robert, Clément, Jacques, Durand, Florence, Combet, Romain, Perraut, Pierre, Leroy, Vincent, Gay, Frédéric, Lefrançois, Dominique, Bretin, François, Marquette, Jean-Pierre, Michot, Nadine, Caron, Anne, Castell, Christelle, Schio, Laurent, McCort, Gary, Goulaouic, Hélène, Garcia-Echeverria, Carlos, Ronan, Baptiste
Published in Journal of medicinal chemistry (08.01.2015)
Published in Journal of medicinal chemistry (08.01.2015)
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Journal Article
Evolution in the management of vestibular schwannoma: a single-center 15-year experience
El Sayed Ahmad, Youssef, Gallois, Yohan, Sol, Jean Christophe, Boetto, Sergio, Attal, Justine, Sabatier, Jean, Debs, Rachel, Deguine, Olivier, Marx, Mathieu
Published in European archives of oto-rhino-laryngology (01.11.2023)
Published in European archives of oto-rhino-laryngology (01.11.2023)
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Pituitary apoplexy: a systematic review of non-gestational risk factors
Kajal, Smile, Ahmad, Youssef El Sayed, Halawi, Akaber, Gol, Mohammad Abraham Kazemizadeh, Ashley, William
Published in Pituitary (01.08.2024)
Published in Pituitary (01.08.2024)
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SAR439859, a Novel Selective Estrogen Receptor Degrader (SERD), Demonstrates Effective and Broad Antitumor Activity in Wild-Type and Mutant ER-Positive Breast Cancer Models
Shomali, Maysoun, Cheng, Jane, Sun, Fangxian, Koundinya, Malvika, Guo, Zhuyan, Hebert, Andrew T, McManus, Jessica, Levit, Mikhail N, Hoffmann, Dietmar, Courjaud, Albane, Arrebola, Rosalia, Cao, Hui, Pollard, Jack, Lee, Joon Sang, Besret, Laurent, Caron, Anne, Bangari, Dinesh S, Abecassis, Pierre-Yves, Schio, Laurent, El-Ahmad, Youssef, Halley, Frank, Tabart, Michel, Certal, Victor, Thompson, Fabienne, McCort, Gary, Filoche-Rommé, Bruno, Cheng, Hong, Garcia-Echeverria, Carlos, Debussche, Laurent, Bouaboula, Monsif
Published in Molecular cancer therapeutics (01.02.2021)
Published in Molecular cancer therapeutics (01.02.2021)
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Abstract P4-02-08: Amcenestrant in combination with CDK4/6 inhibitor palbociclib demonstrates synergistic anti-tumor activity in ER+ endocrine-resistant breast cancer xenograft models
Shomali, Maysoun, Guo, Zhuyan, Cheng, Jane, Sullivan, Amy, El-Ahmad, Youssef, Sun, Fangxian, Sidhu, Sukhvinder, Lee, Joon Sang, Cai, Hui, Pollard, Jack, Debussche, Laurent, Soria, Chris, Bouaboula, Monsif
Published in Cancer research (Chicago, Ill.) (15.02.2022)
Published in Cancer research (Chicago, Ill.) (15.02.2022)
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Discovery of 6‑(2,4-Dichlorophenyl)-5-[4-[(3S)‑1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro‑7H‑benzo[7]annulene-2-carboxylic acid (SAR439859), a Potent and Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen-Receptor-Positive Breast Cancer
El-Ahmad, Youssef, Tabart, Michel, Halley, Frank, Certal, Victor, Thompson, Fabienne, Filoche-Rommé, Bruno, Gruss-Leleu, Florence, Muller, Claire, Brollo, Maurice, Fabien, Laurence, Loyau, Véronique, Bertin, Luc, Richepin, Patrick, Pilorge, Fabienne, Desmazeau, Pascal, Girardet, Chrystelle, Beccari, Sylvie, Louboutin, Audrey, Lebourg, Gilles, Le-Roux, Jacques, Terrier, Corinne, Vallée, François, Steier, Valérie, Mathieu, Magali, Rak, Alexey, Abecassis, Pierre-Yves, Vicat, Pascale, Benard, Tsiala, Bouaboula, Monsif, Sun, Fangxian, Shomali, Maysoun, Hebert, Andrew, Levit, Mikhail, Cheng, Hong, Courjaud, Albane, Ginesty, Celine, Perrault, Christelle, Garcia-Echeverria, Carlos, McCort, Gary, Schio, Laurent
Published in Journal of medicinal chemistry (23.01.2020)
Published in Journal of medicinal chemistry (23.01.2020)
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Journal Article
Discovery of 6-(2,4-Dichlorophenyl)-5-[4-[(3 S )-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7 H -benzo[7]annulene-2-carboxylic acid (SAR439859), a Potent and Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen-Receptor-Positive Breast Cancer
El-Ahmad, Youssef, Tabart, Michel, Halley, Frank, Certal, Victor, Thompson, Fabienne, Filoche-Rommé, Bruno, Gruss-Leleu, Florence, Muller, Claire, Brollo, Maurice, Fabien, Laurence, Loyau, Véronique, Bertin, Luc, Richepin, Patrick, Pilorge, Fabienne, Desmazeau, Pascal, Girardet, Chrystelle, Beccari, Sylvie, Louboutin, Audrey, Lebourg, Gilles, Le-Roux, Jacques, Terrier, Corinne, Vallée, François, Steier, Valérie, Mathieu, Magali, Rak, Alexey, Abecassis, Pierre-Yves, Vicat, Pascale, Benard, Tsiala, Bouaboula, Monsif, Sun, Fangxian, Shomali, Maysoun, Hebert, Andrew, Levit, Mikhail, Cheng, Hong, Courjaud, Albane, Ginesty, Celine, Perrault, Christelle, Garcia-Echeverria, Carlos, McCort, Gary, Schio, Laurent
Published in Journal of medicinal chemistry (23.01.2020)
Published in Journal of medicinal chemistry (23.01.2020)
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Abstract PS17-16: Sar439859, a novel selective estrogen receptor degrader (serd), demonstrates effective and broad antitumor activity in wild-type and mutant er-positive breast cancer models
Shomali, Maysoun, Sun, Fangxian, Levit, Mikhail, Pollard, Jack, Lee, Joon Sang, Schio, Laurent, El-Ahmad, Youssef, Soria, Chris, Cohen, Patrick, Debussche, Laurent, Bouaboula, Monsif
Published in Cancer research (Chicago, Ill.) (15.02.2021)
Published in Cancer research (Chicago, Ill.) (15.02.2021)
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Journal Article
Abstract 3452: Pre-clinical development of next generation selective estrogen receptor degrader - SAR439859
Sun, Fangxian, Cheng, Jane, Sullivan, Amy, Malkova, Natalia, Shomali, Maysoun, McManus, Jesseca, Levit, Mikhail, Bangari, Dinesh, El-Ahmad, Youssef, Sidhu, Sukhvinder, Debussche, Laurent, Bouaboula, Monsif
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Optimization and Gram-Scale Preparation of S‑Trifluoromethyl Sulfoximines and Sulfilimino Iminiums, Powerful Reagents for the Late Stage Introduction of the CF3 Group
Barthelemy, Anne-Laure, Certal, Victor, Dagousset, Guillaume, Anselmi, Elsa, Bertin, Luc, Fabien, Laurence, Salgues, Bruno, Courtes, Philippe, Poma, Christian, El-Ahmad, Youssef, Magnier, Emmanuel
Published in Organic process research & development (15.05.2020)
Published in Organic process research & development (15.05.2020)
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Scalable Synthesis of (R,R)‑N,N‑Dibenzyl-2-fluorocyclohexan-1-amine with CsF under Hydrogen Bonding Phase-Transfer Catalysis
Vicini, Anna Chiara, Alozie, Diké-Michel, Courtes, Philippe, Roagna, Giulia, Aubert, Catherine, Certal, Victor, El-Ahmad, Youssef, Roy, Sébastien, Gouverneur, Véronique
Published in Organic process research & development (17.12.2021)
Published in Organic process research & development (17.12.2021)
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Journal Article
Optimization and Gram-Scale Preparation of S -Trifluoromethyl Sulfoximines and Sulfilimino Iminiums, Powerful Reagents for the Late Stage Introduction of the CF 3 Group
Barthelemy, Anne-Laure, Certal, Victor, Dagousset, Guillaume, Anselmi, Elsa, Bertin, Luc, Fabien, Laurence, Salgues, Bruno, Courtes, Philippe, Poma, Christian, El-Ahmad, Youssef, Magnier, Emmanuel
Published in Organic process research & development (15.05.2020)
Published in Organic process research & development (15.05.2020)
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Journal Article
Optimization and Gram-Scale Preparation of S -Trifluoromethyl Sulfoximines and Sulfilimino Iminiums, Powerful Reagents for the Late Stage Introduction of the CF 3 Group
Barthelemy, Anne-Laure, Certal, Victor, Dagousset, Guillaume, Anselmi, Elsa, Bertin, Luc, Fabien, Laurence, Salgues, Bruno, Courtes, Philippe, Poma, Christian, El-Ahmad, Youssef, Magnier, Emmanuel
Published in Organic process research & development (15.05.2020)
Published in Organic process research & development (15.05.2020)
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Journal Article
Discovery and Optimization of Pyrimidone Indoline Amide P13K beta Inhibitors for the Treatment of Phosphatase and Tensin Homologue (PTEN)-Deficient Cancers
Certal, Victor, Carry, Jean-Christophe, Halley, Frank, Virone-Oddos, Angela, Thompson, Fabienne, Filoche-Romme, Bruno, El-Ahmad, Youssef, Karlsson, Andreas, Charrier, Veronique, Delorme, Cecile, Rak, Alexey, Abecassis, Pierre-Yves, Amara, Celine, Vincent, Loic, Bonnevaux, Helene, Nicolas, Jean-Paul, Mathieu, Magali, Bertrand, Thomas, Marquette, Jean-Pierre, Michot, Nadine, Benard, Tsiala, Perrin, Marc-Antoine, Lemaitre, Olivier, Guerif, Stephane, Perron, Sebastien, Monget, Sylvie, Gruss-Leleu, Florence, Doerflinger, Gilles, Guizani, Houlfa, Brollo, Maurice, Delbarre, Laurence, Benin, Luc, Richepin, Patrick, Loyau, Veronique, Garcia-Echeverria, Carlos, Lengauer, Christoph, Schio, Laurent
Published in Journal of medicinal chemistry (13.02.2014)
Published in Journal of medicinal chemistry (13.02.2014)
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Journal Article
Discovery of (2 S )-8-[(3 R )-3-Methylmorpholin-4-yl]-1-(3-methyl-2-oxobutyl)-2-(trifluoromethyl)-3,4-dihydro-2 H -pyrimido[1,2- a ]pyrimidin-6-one: A Novel Potent and Selective Inhibitor of Vps34 for the Treatment of Solid Tumors
Pasquier, Benoit, El-Ahmad, Youssef, Filoche-Rommé, Bruno, Dureuil, Christine, Fassy, Florence, Abecassis, Pierre-Yves, Mathieu, Magali, Bertrand, Thomas, Benard, Tsiala, Barrière, Cédric, El Batti, Samira, Letallec, Jean-Philippe, Sonnefraud, Véronique, Brollo, Maurice, Delbarre, Laurence, Loyau, Véronique, Pilorge, Fabienne, Bertin, Luc, Richepin, Patrick, Arigon, Jérôme, Labrosse, Jean-Robert, Clément, Jacques, Durand, Florence, Combet, Romain, Perraut, Pierre, Leroy, Vincent, Gay, Frédéric, Lefrançois, Dominique, Bretin, François, Marquette, Jean-Pierre, Michot, Nadine, Caron, Anne, Castell, Christelle, Schio, Laurent, McCort, Gary, Goulaouic, Hélène, Garcia-Echeverria, Carlos, Ronan, Baptiste
Published in Journal of medicinal chemistry (08.01.2015)
Published in Journal of medicinal chemistry (08.01.2015)
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Journal Article
Discovery and Optimization of Pyrimidone Indoline Amide PI3Kβ Inhibitors for the Treatment of Phosphatase and Tensin Homologue (PTEN)-Deficient Cancers
Certal, Victor, Carry, Jean-Christophe, Halley, Frank, Virone-Oddos, Angela, Thompson, Fabienne, Filoche-Rommé, Bruno, El-Ahmad, Youssef, Karlsson, Andreas, Charrier, Véronique, Delorme, Cécile, Rak, Alexey, Abecassis, Pierre-Yves, Amara, Céline, Vincent, Loïc, Bonnevaux, Hélène, Nicolas, Jean-Paul, Mathieu, Magali, Bertrand, Thomas, Marquette, Jean-Pierre, Michot, Nadine, Benard, Tsiala, Perrin, Marc-Antoine, Lemaitre, Olivier, Guerif, Stephane, Perron, Sébastien, Monget, Sylvie, Gruss-Leleu, Florence, Doerflinger, Gilles, Guizani, Houlfa, Brollo, Maurice, Delbarre, Laurence, Bertin, Luc, Richepin, Patrick, Loyau, Véronique, Garcia-Echeverria, Carlos, Lengauer, Christoph, Schio, Laurent
Published in Journal of medicinal chemistry (13.02.2014)
Published in Journal of medicinal chemistry (13.02.2014)
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Abstract 943: SAR439859, an orally bioavailable selective estrogen receptor degrader (SERD) that demonstrates robust antitumor efficacy and limited cross-resistance in ER+ breast cancer
Bouaboula, Monsif, Shomali, Maysoun, Cheng, Jane, Malkova, Natalia, Sun, Fangxian, Koundinya, Malvika, Guo, Zhuyan, Poirier, Stephane, Levit, Mikhail, Hoffman, Dietmar, Cao, Hui, Bestret, Laurent, Adrian, Francisco, Winter, Christoph, El-Ahmad, Youssef, Vincent, Sylvie, Halley, Frank, McCort, Gary, Schio, Laurent, Richon, Vicky, Cheng, Hong, Hsu, Karl, Soria, Chris, Cohen, Patrick, Lager, Joanne, Garcia-Echeverria, Carlos, Debussche, Laurent
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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