A New Water‐soluble Camptothecin Derivative, DX‐8951f, Exhibits Potent Antitumor Activity against Human Tumors in vitro and in vivo
Mitsui, Ikuo, Kumazawa, Eiji, Hirota, Yasuhide, Aonuma, Masashi, Sugimori, Masamichi, Ohsuki, Satoru, Uoto, Kouichi, Ejima, Akio, Terasawa, Hirofumi, Sato, Keiki
Published in Cancer science (01.08.1995)
Published in Cancer science (01.08.1995)
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Synthesis and Antitumor Activity of Novel Pyrimidinyl Pyrazole Derivatives. III. Synthesis and Antitumor Activity of 3-Phenylpiperazinyl-1-trans-propenes
Naito, Hiroyuki, Ohsuki, Satoru, Atsumi, Ryo, Minami, Megumi, Mochizuki, Mineko, Hirotani, Kenji, Kumazawa, Eiji, Ejima, Akio
Published in Chemical & pharmaceutical bulletin (01.02.2005)
Published in Chemical & pharmaceutical bulletin (01.02.2005)
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Identified a morpholinyl-4-piperidinylacetic acid derivative as a potent oral active VLA-4 antagonist
Chiba, Jun, Machinaga, Nobuo, Takashi, Tohru, Ejima, Akio, Takayama, Gensuke, Yokoyama, Mika, Nakayama, Atsushi, Baldwin, John J., McDonald, Edward, Saionz, Kurt W., Swanson, Robert, Hussain, Zahid, Wong, Angela
Published in Bioorganic & medicinal chemistry letters (03.01.2005)
Published in Bioorganic & medicinal chemistry letters (03.01.2005)
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Synthesis and Antitumor Activity of Novel Pyrimidinyl Pyrazole Derivatives. II. Optimization of the Phenylpiperazine Moiety of 1-[5-Methyl-1-(2-pyrimidinyl)-4-pyrazolyl]-3-phenylpiperazinyl-1-trans-propenes
Naito, Hiroyuki, Ohsuki, Satoru, Sugimori, Masamichi, Atsumi, Ryo, Minami, Megumi, Nakamura, Yoshihide, Ishii, Mineko, Hirotani, Kenji, Kumazawa, Eiji, Ejima, Akio
Published in Chemical & pharmaceutical bulletin (01.04.2002)
Published in Chemical & pharmaceutical bulletin (01.04.2002)
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Growth inhibitory effect of a new camptothecin analog, DX-8951f, on various drug-resistant sublines including BCRP-mediated camptothecin derivative-resistant variants derived from the human lung cancer cell line PC-6
Ishii, M, Iwahana, M, Mitsui, I, Minami, M, Imagawa, S, Tohgo, A, Ejima, A
Published in Anti-cancer drugs (01.06.2000)
Published in Anti-cancer drugs (01.06.2000)
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Synthesis and Antitumor Activity of Novel Pyrimidinyl Pyrazole Derivatives
NAITO, Hiroyuki, SUGIMORI, Masamichi, MITSUI, Ikuo, NAKAMURA, Yoshihide, IWAHANA, Michio, ISHII, Mineko, HIROTANI, Kenji, KUMAZAWA, Eiji, EJIMA, Akio
Published in Chemical & pharmaceutical bulletin (01.12.1999)
Published in Chemical & pharmaceutical bulletin (01.12.1999)
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Synthesis and Antitumor Activity of Novel Benzophenone Derivatives
KUMAZAWA, Eiji, HIROTANI, Kenji, BURFORD, S. Clifford, KAWAGOE, Keiichi, MIWA, Tamotsu, MITSUI, Ikuo, EJIMA, Akio
Published in Chemical & pharmaceutical bulletin (01.09.1997)
Published in Chemical & pharmaceutical bulletin (01.09.1997)
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SYNTHETIC DUAL INHIBITORS OF DNA TOPOISOMERASE I AND II
KATAYAMA, Hajime, KAWADA, Yusuke, OSHIYAMA, Takamitu, EJIMA, Akio
Published in Chemical & pharmaceutical bulletin (1996)
Published in Chemical & pharmaceutical bulletin (1996)
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Semisynthetic .BETA.-lactam antibiotics. II Synthesis and antibacterial activity of 7.BETA.-(2-(acylamino)-2-(2-aminothiazol-4-yl)acetamido)cephalosporins
ARIMOTO, MASAHIRO, EJIMA, AKIO, WATANABE, TOSHIFUMI, TAGAWA, HIROAKI, FURUKAWA, MINORU
Published in Journal of antibiotics (1986)
Published in Journal of antibiotics (1986)
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SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF CEPHALOSPORINS WITH A 1-PYRIDINIUM SUBSTITUENT CARRYING A 5-MEMBERED HETEROCYCLE AT THE C-3 POSITION
EJIMA, AKIO, HAYANO, TAKESHI, EBATA, TSUTOMU, NAGAHARA, TAKAYASU, KODA, HIROKO, TAGAWA, HIROAKI, FURUKAWA, MINORU
Published in Journal of antibiotics (01.01.1987)
Published in Journal of antibiotics (01.01.1987)
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Semisynthetic .BETA.-lactam antibiotics. I Synthesis and antibacterial activity of 7.BETA.-(2-aryl-2-(aminoacetamido)acetamido)cephalosporins
FURUKAWA, MINORU, ARIMOTO, MASAHIRO, NAKAMURA, SHIGETAKE, EJIMA, AKIO, HIGASHI, YOHKO, TAGAWA, HIROAKI
Published in Journal of antibiotics (1986)
Published in Journal of antibiotics (1986)
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Synthesis and mechanism of action of novel pyrimidinyl pyrazole derivatives possessing antiproliferative activity
Ohki, Hitoshi, Hirotani, Kenji, Naito, Hiroyuki, Ohsuki, Satoru, Minami, Megumi, Ejima, Akio, Koiso, Yukiko, Hashimoto, Yuichi
Published in Bioorganic & medicinal chemistry letters (04.11.2002)
Published in Bioorganic & medicinal chemistry letters (04.11.2002)
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Antitumor activities of ketol forms of unsaturated fatty acids from a water extract of corn grain
Ishihara, N. (Tamanoi Vinegar Co. Ltd., Osaka (Japan)), Nakagawa, K, Saito, F, Uenakai, K, Kuga, H, Ejima, A, Mitsui, I, Sato, K
Published in Nippon Nōgeikagaku Kaishi (01.10.1993)
Published in Nippon Nōgeikagaku Kaishi (01.10.1993)
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A Synthesis of 3′-Deoxybutirosin B
Watanabe, Isamu, Ejima, Akio, Tsuchiya, Tsutomu, Ikeda, Daishiro, Umezawa, Sumio
Published in Bulletin of the Chemical Society of Japan (01.02.1977)
Published in Bulletin of the Chemical Society of Japan (01.02.1977)
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