The inophyllums, novel inhibitors of HIV-1 reverse transcriptase isolated from the Malaysian tree, Calophyllum inophyllum Linn
Patil, Ashok D, Freyer, Alan J, Eggleston, Drake S, Haltiwanger, R. Curtis, Bean, Mark F, Taylor, Paul B, Caranfa, Mary Jo, Breen, Ann L, Bartus, Henry R
Published in Journal of medicinal chemistry (24.12.1993)
Published in Journal of medicinal chemistry (24.12.1993)
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Discovery of a Novel Class of Substituted Pyrrolooctahydroisoquinolines as Potent and Selective δ Opioid Agonists, Based on an Extension of the Message−Address Concept
Dondio, Giulio, Ronzoni, Silvano, Eggleston, Drake S, Artico, Marco, Petrillo, Paola, Petrone, Giuseppe, Visentin, Luciano, Farina, Carlo, Vecchietti, Vittorio, Clarke, Geoffrey D
Published in Journal of medicinal chemistry (26.09.1997)
Published in Journal of medicinal chemistry (26.09.1997)
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Inhibitors of bacterial tyrosyl tRNA synthetase: synthesis of four stereoisomeric analogues of the natural product SB-219383
Berge, John M, Copley, Royston C.B, Eggleston, Drake S, Hamprecht, Dieter W, Jarvest, Richard L, Mensah, Lucy M, O'Hanlon, Peter J, Pope, Andrew J
Published in Bioorganic & medicinal chemistry letters (21.08.2000)
Published in Bioorganic & medicinal chemistry letters (21.08.2000)
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Non-thiazolidinedione antihyperglycaemic agents. Part 3: the effects of stereochemistry on the potency of α-methoxy-β-phenylpropanoic acids
Haigh, David, Allen, Graham, Birrell, Helen C., Buckle, Derek R., Cantello, Barrie C.C., Eggleston, Drake S., Haltiwanger, R.Curtis, Holder, Julie C., Lister, Carolyn A., Pinto, Ivan L., Rami, Harshad K., Sime, John T., Smith, Stephen A., Sweeney, John D.
Published in Bioorganic & medicinal chemistry (01.05.1999)
Published in Bioorganic & medicinal chemistry (01.05.1999)
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Journal Article
The crystal structure, absolute configuration, and phosphodiesterase inhibitory activity of (+)-1-(4-bromobenzyl)-4-(3-cyclopentyloxy)-4-methoxyphenyl-pyrrolidin-2-one
BAURES, P. W, EGGLESTON, D. S, ERHARD, K. F, CIESLINSKI, L. B, TORPHY, T. J, CHRISTENSEN, S. B
Published in Journal of medicinal chemistry (29.10.1993)
Published in Journal of medicinal chemistry (29.10.1993)
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Investigation of conformational specificity at GPIIb/IIIa: evaluation of conformationally constrained RGD peptides
Peishoff, Catherine E, Ali, Fadia E, Bean, John W, Calvo, Raul, D'Ambrosio, Cynthia A, Eggleston, Drake S, Kline, Tammy Page, Koster, Paul F, Hwang, S. M
Published in Journal of medicinal chemistry (01.10.1992)
Published in Journal of medicinal chemistry (01.10.1992)
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ATP-Citrate Lyase as a Target for Hypolipidemic Intervention. 2. Synthesis and Evaluation of (3R,5S)-ω-Substituted-3-carboxy-3,5-dihydroxyalkanoic Acids and Their γ-Lactone Prodrugs as Inhibitors of the Enzyme in Vitro and in Vivo
Gribble, Andrew D, Ife, Robert J, Shaw, Antony, McNair, David, Novelli, Christine E, Bakewell, Susan, Shah, Virendra P, Dolle, Roland E, Groot, Pieter H, Pearce, Nigel, Yates, John, Tew, David, Boyd, Helen, Ashman, Stephen, Eggleston, Drake S, Haltiwanger, R. Curtis, Okafo, George
Published in Journal of medicinal chemistry (10.09.1998)
Published in Journal of medicinal chemistry (10.09.1998)
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Apakaochtodenes A and B: Two Tetrahalogenated Monoterpenes from the Red Marine Alga Portieria hornemannii
Gunatilaka, A. A. Leslie, Paul, Valerie J, Park, Peter U, Puglisi, Melany P, Gitler, Aaron D, Eggleston, Drake S, Haltiwanger, R. Curtis, Kingston, David G. I
Published in Journal of natural products (Washington, D.C.) (01.10.1999)
Published in Journal of natural products (Washington, D.C.) (01.10.1999)
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Journal Article
Synthesis and Recognition Properties of Aromatic Amide Oligomers: Molecular Zippers
Bisson, Adrian P, Carver, Fiona J, Eggleston, Drake S, Haltiwanger, R. Curtis, Hunter, Christopher A, Livingstone, David L, McCabe, James F, Rotger, Carmen, Rowan, Alan E
Published in Journal of the American Chemical Society (20.09.2000)
Published in Journal of the American Chemical Society (20.09.2000)
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1,4-Cyclohexanecarboxylates: Potent and Selective Inhibitors of Phosophodiesterase 4 for the Treatment of Asthma
Christensen, Siegfried B, Guider, Aimee, Forster, Cornelia J, Gleason, John G, Bender, Paul E, Karpinski, Joseph M, DeWolf, Walter E, Barnette, Mary S, Underwood, David C, Griswold, Don E, Cieslinski, Lenora B, Burman, Miriam, Bochnowicz, Steven, Osborn, Ruth R, Manning, Carol D, Grous, Marilyn, Hillegas, Leonard M, Bartus, Joan O'Leary, Ryan, M. Dominic, Eggleston, Drake S, Haltiwanger, R. Curtis, Torphy, Theodore J
Published in Journal of medicinal chemistry (12.03.1998)
Published in Journal of medicinal chemistry (12.03.1998)
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Molecular structures of L-Leu-L-Tyr, Gly-D,L-Met.p-toluenesulfonate and L-His-L-Leu
Krause, J A, Baures, P W, Eggleston, D S
Published in Acta crystallographica. Section B, Structural science (01.02.1993)
Published in Acta crystallographica. Section B, Structural science (01.02.1993)
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Two New Nitrogenous Sesquiterpenes from the Sponge Axinyssa aplysinoides
Patil, Ashok D, Freyer, Alan J, Reichwein, Rex, Bean, Mark F, Faucette, Leo, Johnson, Randall K, Haltiwanger, R. Curtis, Eggleston, Drake S
Published in Journal of natural products (Washington, D.C.) (01.05.1997)
Published in Journal of natural products (Washington, D.C.) (01.05.1997)
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Imidazole-5-acrylic acids: potent nonpeptide angiotensin II receptor antagonists designed using a novel peptide pharmacophore model
Keenan, R. M, Weinstock, J, Finkelstein, J. A, Franz, R. G, Gaitanopoulos, D. E, Girard, G. R, Hill, D. T, Morgan, T. M, Samanen, J. M
Published in Journal of medicinal chemistry (01.10.1992)
Published in Journal of medicinal chemistry (01.10.1992)
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The structure of ribonuclease P protein from Staphylococcus aureus reveals a unique binding site for single-stranded RNA
Spitzfaden, Claus, Nicholson, Neville, Jones, Jo J, Guth, Sabine, Lehr, Ruth, Prescott, Cathy D, Hegg, Lisa A, Eggleston, Drake S
Published in Journal of molecular biology (07.01.2000)
Published in Journal of molecular biology (07.01.2000)
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Journal Article
Conformational Preferences in a Benzodiazepine Series of Potent Nonpeptide Fibrinogen Receptor Antagonists
Keenan, Richard M, Callahan, James F, Samanen, James M, Bondinell, William E, Calvo, Raul R, Chen, Lichong, DeBrosse, Charles, Eggleston, Drake S, Haltiwanger, R. Curtis, Hwang, Shing Mei, Jakas, Dalia R, Ku, Thomas W, Miller, William H, Newlander, Kenneth A, Nichols, Andrew, Parker, Michael F, Southhall, Linda S, Uzinskas, Irene, Vasko-Moser, Janice A, Venslavsky, Joseph W, Wong, Angela S, Huffman, William F
Published in Journal of medicinal chemistry (25.02.1999)
Published in Journal of medicinal chemistry (25.02.1999)
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Proline conformations in linear peptides. Structure determination of the methyl ester of N-benzyloxycarbonyl-L-prolyl-D-alanine (N-Z-L-Pro-D-Ala-OMe)
Krause, J A, Eggleston, D S
Published in Acta crystallographica. Section C, Crystal structure communications (15.07.1991)
Published in Acta crystallographica. Section C, Crystal structure communications (15.07.1991)
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Journal Article
Structure–activity analysis of truncated orexin-A analogues at the orexin-1 receptor
Darker, John G, Porter, Roderick A, Eggleston, Drake S, Smart, Darren, Brough, Stephen J, Sabido-David, Cibele, Jerman, Jeffrey C
Published in Bioorganic & medicinal chemistry letters (12.03.2001)
Published in Bioorganic & medicinal chemistry letters (12.03.2001)
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