RIG-1-Like Receptor Activation Synergizes With Intratumoral Alpha Radiation to Induce Pancreatic Tumor Rejection, Triple-Negative Breast Metastases Clearance, and Antitumor Immune Memory in Mice
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Published in Frontiers in oncology (17.07.2020)
Published in Frontiers in oncology (17.07.2020)
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Human apoE3 but not apoE4 rescues impaired astrocyte activation in apoE null mice
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Published in Neurobiology of disease (01.02.2003)
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Diffusing Alpha-Emitters Radiation Therapy Promotes a Proimmunogenic Tumor Microenvironment and Synergizes With Programmed Cell Death Protein 1 Blockade
Mare, Sara Del, Nishri, Yossi, Shai, Amit, Efrati, Margalit, Deutsch, Lisa, Den, Robert B., Kelson, Itzhak, Keisari, Yona, Domankevich, Vered
Published in International journal of radiation oncology, biology, physics (01.03.2023)
Published in International journal of radiation oncology, biology, physics (01.03.2023)
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Inhibition of mouse breast adenocarcinoma growth by ablation with intratumoral alpha-irradiation combined with inhibitors of immunosuppression and CpG
Confino, Hila, Schmidt, Michael, Efrati, Margalit, Hochman, Ilan, Umansky, Viktor, Kelson, Itzhak, Keisari, Yona
Published in Cancer Immunology, Immunotherapy (01.10.2016)
Published in Cancer Immunology, Immunotherapy (01.10.2016)
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Combining alpha radiation-based brachytherapy with immunomodulators promotes complete tumor regression in mice via tumor-specific long-term immune response
Domankevich, Vered, Cohen, Adi, Efrati, Margalit, Schmidt, Michael, Rammensee, Hans-Georg, Nair, Sujit S., Tewari, Ashutosh, Kelson, Itzhak, Keisari, Yona
Published in Cancer Immunology, Immunotherapy (01.12.2019)
Published in Cancer Immunology, Immunotherapy (01.12.2019)
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Tumor ablation by intratumoral Ra-224-loaded wires induces anti-tumor immunity against experimental metastatic tumors
Confino, Hila, Hochman, Ilan, Efrati, Margalit, Schmidt, Michael, Umansky, Viktor, Kelson, Itzhak, Keisari, Yona
Published in Cancer Immunology, Immunotherapy (01.02.2015)
Published in Cancer Immunology, Immunotherapy (01.02.2015)
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428 Diffusing alpha-emitters radiation therapy promotes a pro-immunogenic tumor microenvironment and synergizes with PD-1 blockade
Roumani, Sara, Nishri, Yossi, Shai, Amit, Efrati, Margalit, Kelson, Itzhak, Keisari, Yona, Domankevich, Vered, Den, Robert
Published in Journal for immunotherapy of cancer (01.11.2022)
Published in Journal for immunotherapy of cancer (01.11.2022)
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Immunomodulation of the Antitumor Response Induced by Alpha Radiation-Based Brachytherapy Results in the Elimination of Spontaneous Lung Metastases in a Triple Negative Breast Cancer Mice Model and in the Cure of Colon Cancer Bearing Mice
Domankevich-Bachar, Vered, Cohen, Adi, Efrati, Margalit, Schmidt, Michael, Galalae, Razvan Galalae, Kelson, Itzhak, Keisari, Yona
Published in Brachytherapy (01.05.2019)
Published in Brachytherapy (01.05.2019)
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면역 체크포인트 조절자와 조합된 종양내 알파 방출 방사선
MANSOUR FAIRUZ, DEN ROBERT, EFRATI MARGALIT, SHAI AMIT, NISHRI YOSSI, DOMANKEVICH VERED, DEL MARE ROUMANI SARA, KEISARI YONA, SEGAL RONEN, KELSON ITZHAK
Year of Publication 28.02.2024
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Year of Publication 28.02.2024
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혈관 억제제와 조합된 종양내 알파 방출 방사선
LUZ ISHAI, DEN ROBERT, NISHRI YOSSI, EFRATI MARGALIT, SHAI AMIT, DOMANKEVICH VERED, DEL MARE ROUMANI SARA, KEISARI YONA, SEGAL RONEN, KELSON ITZHAK, COOKS TOMER, VATARESCU MAAYAN HEDVA
Year of Publication 27.02.2024
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Year of Publication 27.02.2024
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Interstitial wires releasing diffusing alpha emitters combined with chemotherapy improved local tumor control and survival in squamous cell carcinoma‐bearing mice
Cooks, Tomer, Arazi, Lior, Efrati, Margalit, Schmidt, Michael, Marshak, Gideon, Kelson, Itzhak, Keisari, Yona
Published in Cancer (15.04.2009)
Published in Cancer (15.04.2009)
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Ablation of experimental colon cancer by intratumoral 224 Radium-loaded wires is mediated by alpha particles released from atoms which spread in the tumor and can be augmented by chemotherapy
Reitkopf-Brodutch, Shira, Confino, Hila, Schmidt, Michael, Cooks, Tomer, Efrati, Margalit, Arazi, Lior, Rath-Wolfson, Lea, Marshak, Gideon, Kelson, Itzhak, Keisari, Yona
Published in International journal of radiation biology (01.02.2015)
Published in International journal of radiation biology (01.02.2015)
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Ablation of experimental colon cancer by intratumoral 224Radium-loaded wires is mediated by alpha particles released from atoms which spread in the tumor and can be augmented by chemotherapy
Reitkopf-Brodutch, Shira, Confino, Hila, Schmidt, Michael, Cooks, Tomer, Efrati, Margalit, Arazi, Lior, Rath-Wolfson, Lea, Marshak, Gideon, Kelson, Itzhak, Keisari, Yona
Published in International journal of radiation biology (01.02.2015)
Published in International journal of radiation biology (01.02.2015)
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Intratumoral 224Ra-Loaded Wires Spread Alpha-Emitters Inside Solid Human Tumors in Athymic Mice Achieving Tumor Control
COOKS, Tomer, TAL, Michal, KEISARI, Yona, RAAB, Sefi, EFRATI, Margalit, REITKOPF, Shira, LAZAROV, Elinor, ETZYONI, Revital, SCHMIDT, Michael, ARAZI, Lior, KELSON, Itzhak
Published in Anticancer research (01.12.2012)
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Published in Anticancer research (01.12.2012)
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Local control of experimental malignant pancreatic tumors by treatment with a combination of chemotherapy and intratumoral224 Radium-loaded wires releasing alpha-emitting atoms
Horev-Drori, Galit, Cooks, Tomer, Bittan, Hadas, Lazarov, Elinor, Schmidt, Michael, Arazi, Lior, Efrati, Margalit, Kelson, Itzhak, Keisari, Yona
Published in Translational research : the journal of laboratory and clinical medicine (2012)
Published in Translational research : the journal of laboratory and clinical medicine (2012)
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Journal Article
Local control of experimental malignant pancreatic tumors by treatment with a combination of chemotherapy and intratumoral 224Radium-loaded wires releasing alpha-emitting atoms
Horev-Drori, Galit, Cooks, Tomer, Bittan, Hadas, Lazarov, Elinor, Schmidt, Michael, Arazi, Lior, Efrati, Margalit, Kelson, Itzhak, Keisari, Yona
Published in Translational research : the journal of laboratory and clinical medicine (2012)
Published in Translational research : the journal of laboratory and clinical medicine (2012)
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Comparison of NK activity in mouse spleen and peripheral blood lymphocytes
Yron, I, Erlich, R, Efrati, M, Shohat, L, Witz, I P, Sahar, E
Published in Immunobiology (1979) (01.09.1988)
Published in Immunobiology (1979) (01.09.1988)
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Intratumoral Alpha-Emitter Radiation in Combination with Vasculature Inhibitors
Segal, Ronen, Del Mare Roumani, Sara, Vatarescu, Maayan Hedva, Den, Robert, Keisari, Yona, Cooks, Tomer, Shai, Amit, Luz, Ishai, Kelson, Itzhak, Efrati, Margalit, Nishri, Yossi, Domankevich, Vered
Year of Publication 29.08.2024
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Year of Publication 29.08.2024
Patent
Intratumoral Alpha-Emitter Radiation in Combination with Immune Checkpoint Regulators
Del Mare Roumani, Sara, Segal, Ronen, Mansour, Fairuz, Den, Robert, Keisari, Yona, Shai, Amit, Kelson, Itzhak, Efrati, Margalit, Nishri, Yossi, Domankevich, Vered
Year of Publication 29.08.2024
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Year of Publication 29.08.2024
Patent