A Call for Systematic Research on Solute Carriers
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Published in Cell (30.07.2015)
Published in Cell (30.07.2015)
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Structure and Biochemical Functions of SIRT6
Pan, Patricia W., Feldman, Jessica L., Devries, Mark K., Dong, Aiping, Edwards, Aled M., Denu, John M.
Published in The Journal of biological chemistry (22.04.2011)
Published in The Journal of biological chemistry (22.04.2011)
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Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states
Shintre, Chitra A., Pike, Ashley C. W., Li, Qiuhong, Kim, Jung-In, Barr, Alastair J., Goubin, Solenne, Shrestha, Leela, Yang, Jing, Berridge, Georgina, Ross, Jonathan, Stansfeld, Phillip J., Sansom, Mark S. P., Edwards, Aled M., Bountra, Chas, Marsden, Brian D., von Delft, Frank, Bullock, Alex N., Gileadi, Opher, Burgess-Brown, Nicola A., Carpenter, Elisabeth P.
Published in Proceedings of the National Academy of Sciences - PNAS (11.06.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (11.06.2013)
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Bacteriophage HK97 gp15 Moron Element Encodes a Novel Superinfection Exclusion Protein
Cumby, Nichole, Edwards, Aled M, Davidson, Alan R, Maxwell, Karen L
Published in Journal of Bacteriology (01.09.2012)
Published in Journal of Bacteriology (01.09.2012)
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The Biology/Disease-driven Human Proteome Project (B/D-HPP): Enabling Protein Research for the Life Sciences Community
Aebersold, Ruedi, Bader, Gary D, Edwards, Aled M, van Eyk, Jennifer E, Kussmann, Martin, Qin, Jun, Omenn, Gilbert S
Published in Journal of proteome research (04.01.2013)
Published in Journal of proteome research (04.01.2013)
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A data science roadmap for open science organizations engaged in early-stage drug discovery
Edfeldt, Kristina, Edwards, Aled M., Engkvist, Ola, Günther, Judith, Hartley, Matthew, Hulcoop, David G., Leach, Andrew R., Marsden, Brian D., Menge, Amelie, Misquitta, Leonie, Müller, Susanne, Owen, Dafydd R., Schütt, Kristof T., Skelton, Nicholas, Steffen, Andreas, Tropsha, Alexander, Vernet, Erik, Wang, Yanli, Wellnitz, James, Willson, Timothy M., Clevert, Djork-Arné, Haibe-Kains, Benjamin, Schiavone, Lovisa Holmberg, Schapira, Matthieu
Published in Nature communications (05.07.2024)
Published in Nature communications (05.07.2024)
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Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72
Laflamme, Carl, McKeever, Paul M, Kumar, Rahul, Schwartz, Julie, Kolahdouzan, Mahshad, Chen, Carol X, You, Zhipeng, Benaliouad, Faiza, Gileadi, Opher, McBride, Heidi M, Durcan, Thomas M, Edwards, Aled M, Healy, Luke M, Robertson, Janice, McPherson, Peter S
Published in eLife (15.10.2019)
Published in eLife (15.10.2019)
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Scaling of an antibody validation procedure enables quantification of antibody performance in major research applications
Ayoubi, Riham, Ryan, Joel, Biddle, Michael S, Alshafie, Walaa, Fotouhi, Maryam, Bolivar, Sara Gonzalez, Ruiz Moleon, Vera, Eckmann, Peter, Worrall, Donovan, McDowell, Ian, Southern, Kathleen, Reintsch, Wolfgang, Durcan, Thomas M, Brown, Claire, Bandrowski, Anita, Virk, Harvinder, Edwards, Aled M, McPherson, Peter, Laflamme, Carl
Published in eLife (23.11.2023)
Published in eLife (23.11.2023)
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Chemical Screening Methods to Identify Ligands That Promote Protein Stability, Protein Crystallization, and Structure Determination
Vedadi, Masoud, Niesen, Frank H., Allali-Hassani, Abdellah, Fedorov, Oleg Y., Finerty, Patrick J., Wasney, Gregory A., Yeung, Ron, Arrowsmith, Cheryl, Ball, Linda J., Berglund, Helena, Hui, Raymond, Marsden, Brian D., Nordlund, Pär, Sundstrom, Michael, Weigelt, Johan, Edwards, Aled M.
Published in Proceedings of the National Academy of Sciences - PNAS (24.10.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (24.10.2006)
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Hepatic gene expression discriminates responders and nonresponders in treatment of chronic hepatitis C viral infection
Chen, Limin, Borozan, Ivan, Feld, Jordan, Sun, Jing, Tannis, Laura-Lee, Coltescu, Catalina, Heathcote, Jenny, Edwards, Aled M, McGilvray, Ian D
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2005)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2005)
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A Novel Family of Sequence-specific Endoribonucleases Associated with the Clustered Regularly Interspaced Short Palindromic Repeats
Beloglazova, Natalia, Brown, Greg, Zimmerman, Matthew D., Proudfoot, Michael, Makarova, Kira S., Kudritska, Marina, Kochinyan, Samvel, Wang, Shuren, Chruszcz, Maksymilian, Minor, Wladek, Koonin, Eugene V., Edwards, Aled M., Savchenko, Alexei, Yakunin, Alexander F.
Published in The Journal of biological chemistry (18.07.2008)
Published in The Journal of biological chemistry (18.07.2008)
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The Structural Basis of ZMPSTE24-Dependent Laminopathies
Quigley, Andrew, Dong, Yin Yao, Pike, Ashley C. W., Dong, Liang, Shrestha, Leela, Berridge, Georgina, Stansfeld, Phillip J., Sansom, Mark S. P., Edwards, Aled M., Bountra, Chas, von Delft, Frank, Bullock, Alex N., Burgess-Brown, Nicola A., Carpenter, Elisabeth P.
Published in Science (American Association for the Advancement of Science) (29.03.2013)
Published in Science (American Association for the Advancement of Science) (29.03.2013)
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Genome-wide Analysis of Substrate Specificities of the Escherichia coli Haloacid Dehalogenase-like Phosphatase Family
Kuznetsova, Ekaterina, Proudfoot, Michael, Gonzalez, Claudio F., Brown, Greg, Omelchenko, Marina V., Borozan, Ivan, Carmel, Liran, Wolf, Yuri I., Mori, Hirotada, Savchenko, Alexei V., Arrowsmith, Cheryl H., Koonin, Eugene V., Edwards, Aled M., Yakunin, Alexander F.
Published in The Journal of biological chemistry (24.11.2006)
Published in The Journal of biological chemistry (24.11.2006)
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Polyphosphate-dependent synthesis of ATP and ADP by the family-2 polyphosphate kinases in bacteria
Nocek, Boguslaw, Kochinyan, Samvel, Proudfoot, Michael, Brown, Greg, Evdokimova, Elena, Osipiuk, Jerzy, Edwards, Aled M, Savchenko, Alexei, Joachimiak, Andrzej, Yakunin, Alexander F
Published in Proceedings of the National Academy of Sciences - PNAS (18.11.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (18.11.2008)
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Structural and chemical profiling of the human cytosolic sulfotransferases
Allali-Hassani, Abdellah, Pan, Patricia W, Dombrovski, Ludmila, Najmanovich, Rafael, Tempel, Wolfram, Dong, Aiping, Loppnau, Peter, Martin, Fernando, Thornton, Janet, Thonton, Janet, Edwards, Aled M, Bochkarev, Alexey, Plotnikov, Alexander N, Vedadi, Masoud, Arrowsmith, Cheryl H
Published in PLoS biology (01.05.2007)
Published in PLoS biology (01.05.2007)
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Silencing of USP18 potentiates the antiviral activity of interferon against hepatitis C virus infection
Randall, Glenn, Chen, Limin, Panis, Maryline, Fischer, Andrew K, Lindenbach, Brett D, Sun, Jing, Heathcote, Jenny, Rice, Charles M, Edwards, Aled M, McGilvray, Ian D
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2006)
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2006)
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A guide to selecting high-performing antibodies for Huntingtin (UniProt ID: P42858) for use in western blot, immunoprecipitation, and immunofluorescence [version 1; peer review: awaiting peer review]
Fanti, Rebeka, Ayoubi, Riham, Alende, Charles, Fotouhi, Maryam, González Bolívar, Sara, Chandrasekaran, Renu, Southern, Kathleen, Edwards, Aled M., Harding, Rachel J., Laflamme, Carl
Published in F1000 research (2024)
Published in F1000 research (2024)
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Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins
Zhong, Nan, Loppnau, Peter, Seitova, Alma, Ravichandran, Mani, Fenner, Maria, Jain, Harshika, Bhattacharya, Anandi, Hutchinson, Ashley, Paduch, Marcin, Lu, Vincent, Olszewski, Michal, Kossiakoff, Anthony A, Dowdell, Evan, Koide, Akiko, Koide, Shohei, Huang, Haiming, Nadeem, Vincent, Sidhu, Sachdev S, Greenblatt, Jack F, Marcon, Edyta, Arrowsmith, Cheryl H, Edwards, Aled M, Gräslund, Susanne
Published in PloS one (05.10.2015)
Published in PloS one (05.10.2015)
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Identification of highly specific antibodies for Serine/threonine-protein kinase TBK1 for use in immunoblot, immunoprecipitation and immunofluorescence [version 2; peer review: 2 approved]
Alshafie, Walaa, Fotouhi, Maryam, Shlaifer, Irina, Ayoubi, Riham, Edwards, Aled M., Durcan, Thomas M., McPherson, Peter S., Laflamme, Carl
Published in F1000 research (2022)
Published in F1000 research (2022)
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