Depletion of HIV reservoir by activation of ISR signaling in resting CD4+ T cells
Li, Dajiang, Wong, Lilly M., Tang, Yuyang, Allard, Brigitte, James, Katherine S., Thompson, George R., Dandekar, Satya, Browne, Edward P., Li, Qingsheng, Simon, Jeremy M., Archin, Nancie M., Margolis, David M., Jiang, Guochun
Published in iScience (20.01.2023)
Published in iScience (20.01.2023)
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SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801
Wahl, Angela, Gralinski, Lisa E., Johnson, Claire E., Yao, Wenbo, Kovarova, Martina, Dinnon, Kenneth H., Liu, Hongwei, Madden, Victoria J., Krzystek, Halina M., De, Chandrav, White, Kristen K., Gully, Kendra, Schäfer, Alexandra, Zaman, Tanzila, Leist, Sarah R., Grant, Paul O., Bluemling, Gregory R., Kolykhalov, Alexander A., Natchus, Michael G., Askin, Frederic B., Painter, George, Browne, Edward P., Jones, Corbin D., Pickles, Raymond J., Baric, Ralph S., Garcia, J. Victor
Published in Nature (London) (18.03.2021)
Published in Nature (London) (18.03.2021)
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Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo
Nixon, Christopher C., Mavigner, Maud, Sampey, Gavin C., Brooks, Alyssa D., Spagnuolo, Rae Ann, Irlbeck, David M., Mattingly, Cameron, Ho, Phong T., Schoof, Nils, Cammon, Corinne G., Tharp, Greg K., Kanke, Matthew, Wang, Zhang, Cleary, Rachel A., Upadhyay, Amit A., De, Chandrav, Wills, Saintedym R., Falcinelli, Shane D., Galardi, Cristin, Walum, Hasse, Schramm, Nathaniel J., Deutsch, Jennifer, Lifson, Jeffrey D., Fennessey, Christine M., Keele, Brandon F., Jean, Sherrie, Maguire, Sean, Liao, Baolin, Browne, Edward P., Ferris, Robert G., Brehm, Jessica H., Favre, David, Vanderford, Thomas H., Bosinger, Steven E., Jones, Corbin D., Routy, Jean-Pierre, Archin, Nancie M., Margolis, David M., Wahl, Angela, Dunham, Richard M., Silvestri, Guido, Chahroudi, Ann, Garcia, J. Victor
Published in Nature (London) (06.02.2020)
Published in Nature (London) (06.02.2020)
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A secreted PD-L1 splice variant that covalently dimerizes and mediates immunosuppression
Mahoney, Kathleen M., Shukla, Sachet A., Patsoukis, Nikolaos, Chaudhri, Apoorvi, Browne, Edward P., Arazi, Arnon, Eisenhaure, Thomas M., Pendergraft, William F., Hua, Ping, Pham, Hung C., Bu, Xia, Zhu, Baogong, Hacohen, Nir, Fritsch, Edward F., Boussiotis, Vassiliki A., Wu, Catherine J., Freeman, Gordon J.
Published in Cancer Immunology, Immunotherapy (01.03.2019)
Published in Cancer Immunology, Immunotherapy (01.03.2019)
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A novel high-throughput microwell outgrowth assay for HIV-infected cells
Fenton, Anthony D, Archin, Nancie, Turner, Anne-Marie, Joseph, Sarah, Moeser, Matthew, Margolis, David M, Browne, Edward P
Published in Journal of virology (19.03.2024)
Published in Journal of virology (19.03.2024)
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A histone deacetylase network regulates epigenetic reprogramming and viral silencing in HIV-infected cells
Peterson, Jackson J., Lewis, Catherine A., Burgos, Samuel D., Manickam, Ashokkumar, Xu, Yinyan, Rowley, Allison A., Clutton, Genevieve, Richardson, Brian, Zou, Fei, Simon, Jeremy M., Margolis, David M., Goonetilleke, Nilu, Browne, Edward P.
Published in Cell chemical biology (21.12.2023)
Published in Cell chemical biology (21.12.2023)
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Impact of Cannabis Use on Immune Cell Populations and the Viral Reservoir in People With HIV on Suppressive Antiretroviral Therapy
Falcinelli, Shane D, Cooper-Volkheimer, Alicia D, Semenova, Lesia, Wu, Ethan, Richardson, Alexander, Ashokkumar, Manickam, Margolis, David M, Archin, Nancie M, Rudin, Cynthia D, Murdoch, David, Browne, Edward P
Published in The Journal of infectious diseases (01.12.2023)
Published in The Journal of infectious diseases (01.12.2023)
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Crotonate sensitizes IAPi in the disruption of latent HIV by modulating the ncNF-κB signaling pathway at the step of p100 cleavage into p52
Jiang, Guochun, Li, Dajiang, Falcinelli, Shane D, Wong, Lilly M, Tang, Yuyang, Browne, Edward P, Archin, Nancie M, Margolis, David M
Published in The FASEB journal (01.05.2022)
Published in The FASEB journal (01.05.2022)
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Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses
Lo, Jennifer A, Kawakubo, Masayoshi, Juneja, Vikram R, Su, Mack Y, Erlich, Tal H, LaFleur, Martin W, Kemeny, Lajos V, Rashid, Mamunur, Malehmir, Mohsen, Rabi, S Alireza, Raghavan, Rumya, Allouche, Jennifer, Kasumova, Gyulnara, Frederick, Dennie T, Pauken, Kristen E, Weng, Qing Yu, Pereira da Silva, Marcelo, Xu, Yu, van der Sande, Anita A J, Silkworth, Whitney, Roider, Elisabeth, Browne, Edward P, Lieb, David J, Wang, Belinda, Garraway, Levi A, Wu, Catherine J, Flaherty, Keith T, Brinckerhoff, Constance E, Mullins, David W, Adams, David J, Hacohen, Nir, Hoang, Mai P, Boland, Genevieve M, Freeman, Gordon J, Sharpe, Arlene H, Manstein, Dieter, Fisher, David E
Published in Science translational medicine (17.02.2021)
Published in Science translational medicine (17.02.2021)
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Machine learning approaches identify immunologic signatures of total and intact HIV DNA during long-term antiretroviral therapy
Semenova, Lesia, Wang, Yingfan, Falcinelli, Shane, Archin, Nancie, Cooper-Volkheimer, Alicia D, Margolis, David M, Goonetilleke, Nilu, Murdoch, David M, Rudin, Cynthia D, Browne, Edward P
Published in eLife (09.09.2024)
Published in eLife (09.09.2024)
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Prediction uncertainty and optimal experimental design for learning dynamical systems
Letham, Benjamin, Letham, Portia A, Rudin, Cynthia, Browne, Edward P
Published in Chaos (Woodbury, N.Y.) (01.06.2016)
Published in Chaos (Woodbury, N.Y.) (01.06.2016)
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Combined noncanonical NF-κB agonism and targeted BET bromodomain inhibition reverse HIV latency ex vivo
Falcinelli, Shane D, Peterson, Jackson J, Turner, Anne-Marie W, Irlbeck, David, Read, Jenna, Raines, Samuel Lm, James, Katherine S, Sutton, Cameron, Sanchez, Anthony, Emery, Ann, Sampey, Gavin, Ferris, Robert, Allard, Brigitte, Ghofrani, Simon, Kirchherr, Jennifer L, Baker, Caroline, Kuruc, JoAnn D, Gay, Cynthia L, James, Lindsey I, Wu, Guoxin, Zuck, Paul, Rioja, Inmaculada, Furze, Rebecca C, Prinjha, Rab K, Howell, Bonnie J, Swanstrom, Ronald, Browne, Edward P, Strahl, Brian D, Dunham, Richard M, Archin, Nancie M, Margolis, David M
Published in The Journal of clinical investigation (15.04.2022)
Published in The Journal of clinical investigation (15.04.2022)
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Evaluation of the host transcriptional response to human cytomegalovirus infection
Challacombe, Jean F, Rechtsteiner, Andreas, Gottardo, Raphael, Rocha, Luis M, Browne, Edward P, Shenk, Thomas, Altherr, Michael R, Brettin, Thomas S
Published in Physiological genomics (17.06.2004)
Published in Physiological genomics (17.06.2004)
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Evaluation of EED Inhibitors as a Class of PRC2-Targeted Small Molecules for HIV Latency Reversal
Turner, Anne-Marie W, Dronamraju, Raghuvar, Potjewyd, Frances, James, Katherine S, Winecoff, Daniel K, Kirchherr, Jennifer L, Archin, Nancie M, Browne, Edward P, Strahl, Brian D, Margolis, David M, James, Lindsey I
Published in ACS infectious diseases (10.07.2020)
Published in ACS infectious diseases (10.07.2020)
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Multiplexed enrichment and genomic profiling of peripheral blood cells reveal subset-specific immune signatures
Reyes, Miguel, Vickers, Dwayne, Billman, Kianna, Eisenhaure, Thomas, Hoover, Paul, Browne, Edward P, Rao, Deepak A, Hacohen, Nir, Blainey, Paul C
Published in Science advances (01.01.2019)
Published in Science advances (01.01.2019)
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HSF1 Activation Can Restrict HIV Replication
Nekongo, Emmanuel E, Ponomarenko, Anna I, Dewal, Mahender B, Butty, Vincent L, Browne, Edward P, Shoulders, Matthew D
Published in ACS infectious diseases (10.07.2020)
Published in ACS infectious diseases (10.07.2020)
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PP 4.24 – 00176 Impact of cannabis use on immune cell populations and the viral reservoir in HIV-infected people on suppressive antiretroviral therapy
Falcinelli, Shane D., Volkheimer, Alicia, Semenova, Lesia, Wu, Ethan, Richardson, Alexander, Ashokkumar, Manickam, Margolis, David M, Archin, Nancie M., Rudin, Cynthia D, Murdoch, David, Browne, Edward P
Published in Journal of Virus Eradication (01.12.2022)
Published in Journal of Virus Eradication (01.12.2022)
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