A Metabolic Basis for Endothelial-to-Mesenchymal Transition
Xiong, Jianhua, Kawagishi, Hiroyuki, Yan, Ye, Liu, Jie, Wells, Quinn S., Edmunds, Lia R., Fergusson, Maria M., Yu, Zu-Xi, Rovira, Ilsa I., Brittain, Evan L., Wolfgang, Michael J., Jurczak, Michael J., Fessel, Joshua P., Finkel, Toren
Published in Molecular cell (15.02.2018)
Published in Molecular cell (15.02.2018)
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Journal Article
Liver-specific Prkn knockout mice are more susceptible to diet-induced hepatic steatosis and insulin resistance
Edmunds, Lia R., Xie, Bingxian, Mills, Amanda M., Huckestein, Brydie R., Undamatla, Ramya, Murali, Anjana, Pangburn, Martha M., Martin, James, Sipula, Ian, Kaufman, Brett A., Scott, Iain, Jurczak, Michael J.
Published in Molecular metabolism (Germany) (01.11.2020)
Published in Molecular metabolism (Germany) (01.11.2020)
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Journal Article
Adropin reduces blood glucose levels in mice by limiting hepatic glucose production
Thapa, Dharendra, Xie, Bingxian, Manning, Janet R., Zhang, Manling, Stoner, Michael W., Huckestein, Brydie R., Edmunds, Lia R., Zhang, Xueyang, Dedousis, Nikolaos L., O'Doherty, Robert M., Jurczak, Michael J., Scott, Iain
Published in Physiological reports (01.04.2019)
Published in Physiological reports (01.04.2019)
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Journal Article
c-Myc and AMPK Control Cellular Energy Levels by Cooperatively Regulating Mitochondrial Structure and Function
Edmunds, Lia R, Sharma, Lokendra, Wang, Huabo, Kang, Audry, d'Souza, Sonia, Lu, Jie, McLaughlin, Michael, Dolezal, James M, Gao, Xiaoli, Weintraub, Susan T, Ding, Ying, Zeng, Xuemei, Yates, Nathan, Prochownik, Edward V
Published in PloS one (31.07.2015)
Published in PloS one (31.07.2015)
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Journal Article
GCN5L1 impairs diastolic function in mice exposed to a high fat diet by restricting cardiac pyruvate oxidation
Thapa, Dharendra, Bugga, Paramesha, Mushala, Bellina A. S., Manning, Janet R., Stoner, Michael W., McMahon, Brenda, Zeng, Xuemei, Cantrell, Pamela S., Yates, Nathan, Xie, Bingxian, Edmunds, Lia R., Jurczak, Michael J., Scott, Iain
Published in Physiological reports (01.08.2022)
Published in Physiological reports (01.08.2022)
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Journal Article
Hepatic insulin sensitivity is improved in high‐fat diet‐fed Park2 knockout mice in association with increased hepatic AMPK activation and reduced steatosis
Edmunds, Lia R., Huckestein, Brydie R., Kahn, Mario, Zhang, Dongyan, Chu, Yanxia, Zhang, Yingze, Wendell, Stacy G., Shulman, Gerald I., Jurczak, Michael J.
Published in Physiological reports (01.11.2019)
Published in Physiological reports (01.11.2019)
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Journal Article
Abnormal lipid processing but normal long-term repopulation potential of myc-/- hepatocytes
Edmunds, Lia R, Otero, P Anthony, Sharma, Lokendra, D'Souza, Sonia, Dolezal, James M, David, Sherin, Lu, Jie, Lamm, Lauren, Basantani, Mahesh, Zhang, Pili, Sipula, Ian J, Li, Lucy, Zeng, Xuemei, Ding, Ying, Ding, Fei, Beck, Megan E, Vockley, Jerry, Monga, Satdarshan P S, Kershaw, Erin E, O'Doherty, Robert M, Kratz, Lisa E, Yates, Nathan A, Goetzman, Eric P, Scott, Donald, Duncan, Andrew W, Prochownik, Edward V
Published in Oncotarget (24.05.2016)
Published in Oncotarget (24.05.2016)
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Journal Article
1175-P: Inhibition of FBXO48 Improves Metabolic Changes Associated with NAFLD by Inhibiting Proteasomal Degradation of Phosphorylated AMPKa
MURALI, ANJANA, EDMUNDS, LIA R., XIE, BINGXIAN, CHEN, BILL, LIU, YUAN, JURCZAK, MICHAEL J.
Published in Diabetes (New York, N.Y.) (01.06.2021)
Published in Diabetes (New York, N.Y.) (01.06.2021)
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Journal Article
c-Myc Programs Fatty Acid Metabolism and Dictates Acetyl-CoA Abundance and Fate
Edmunds, Lia R., Sharma, Lokendra, Kang, Audry, Lu, Jie, Vockley, Jerry, Basu, Shrabani, Uppala, Radha, Goetzman, Eric S., Beck, Megan E., Scott, Donald, Prochownik, Edward V.
Published in The Journal of biological chemistry (05.09.2014)
Published in The Journal of biological chemistry (05.09.2014)
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Journal Article
1882-P: Liver-Specific Deletion of the Mitochondrial Quality Control E3 Ligase Parkin Is Associated with Increased Hepatic Steatosis and Markers of NAFLD in Diet-Induced Obese Mice
EDMUNDS, LIA R., MILLS, AMANDA, JURCZAK, MICHAEL J.
Published in Diabetes (New York, N.Y.) (01.06.2019)
Published in Diabetes (New York, N.Y.) (01.06.2019)
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Journal Article
Adropin treatment restores cardiac glucose oxidation in pre-diabetic obese mice
Thapa, Dharendra, Xie, Bingxian, Zhang, Manling, Stoner, Michael W., Manning, Janet R., Huckestein, Brydie R., Edmunds, Lia R., Mullett, Steven J., McTiernan, Charles F., Wendell, Stacy G., Jurczak, Michael J., Scott, Iain
Published in Journal of molecular and cellular cardiology (01.04.2019)
Published in Journal of molecular and cellular cardiology (01.04.2019)
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Journal Article
Coordinated Activities of Multiple Myc-dependent and Myc-independent Biosynthetic Pathways in Hepatoblastoma
Wang, Huabo, Lu, Jie, Edmunds, Lia R., Kulkarni, Sucheta, Dolezal, James, Tao, Junyan, Ranganathan, Sarangarajan, Jackson, Laura, Fromherz, Marc, Beer-Stolz, Donna, Uppala, Radha, Bharathi, Sivakama, Monga, Satdarshan P., Goetzman, Eric S., Prochownik, Edward V.
Published in The Journal of biological chemistry (16.12.2016)
Published in The Journal of biological chemistry (16.12.2016)
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Journal Article
Shear stress and oxygen availability drive differential changes in opossum kidney proximal tubule cell metabolism and endocytosis
Ren, Qidong, Gliozzi, Megan L., Rittenhouse, Natalie L., Edmunds, Lia R., Rbaibi, Youssef, Locker, Joseph D., Poholek, Amanda C., Jurczak, Michael J., Baty, Catherine J., Weisz, Ora A.
Published in Traffic (Copenhagen, Denmark) (01.06.2019)
Published in Traffic (Copenhagen, Denmark) (01.06.2019)
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Journal Article
371-OR: Reduced Hepatic Expression of the Mitochondrial Quality Control Factor PARKIN Hastens the Progression of NAFLD in Mice and Is Associated with NASH in Patients
UNDAMATLA, RAMYA, EDMUNDS, LIA R., XIE, BINGXIAN, MILLS, AMANDA, SIPULA, IAN J., MONGA, SATDARSHAN P., JURCZAK, MICHAEL J.
Published in Diabetes (New York, N.Y.) (01.06.2020)
Published in Diabetes (New York, N.Y.) (01.06.2020)
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Journal Article
Adipocyte JAK2 Regulates Hepatic Insulin Sensitivity Independently of Body Composition, Liver Lipid Content, and Hepatic Insulin Signaling
Corbit, Kevin C, Camporez, João Paulo G, Edmunds, Lia R, Tran, Jennifer L, Vera, Nicholas B, Erion, Derek M, Deo, Rahul C, Perry, Rachel J, Shulman, Gerald I, Jurczak, Michael J, Weiss, Ethan J
Published in Diabetes (New York, N.Y.) (01.02.2018)
Published in Diabetes (New York, N.Y.) (01.02.2018)
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Journal Article
c-Myc programs fatty acid metabolism and dictates acetyl-CoA abundance and fate
Edmunds, Lia R., Sharma, Lokendra, Kang, Audry, Lu, Jie, Vockley, Jerry, Basu, Shrabani, Uppala, Radha, Goetzman, Eric S., Beck, Megan E., Scott, Donald, Prochownik, Edward V.
Published in The Journal of biological chemistry (14.08.2015)
Published in The Journal of biological chemistry (14.08.2015)
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Journal Article
Reduced intestinal lipid absorption and body weight-independent improvements in insulin sensitivity in high-fat diet-fed Park2 knockout mice
Costa, Diana K, Huckestein, Brydie R, Edmunds, Lia R, Petersen, Max C, Nasiri, Ali, Butrico, Gina M, Abulizi, Abudukadier, Harmon, Daniel B, Lu, Canying, Mantell, Benjamin S, Hartman, Douglas J, Camporez, João-Paulo G, O'Doherty, Robert M, Cline, Gary W, Shulman, Gerald I, Jurczak, Michael J
Published in American journal of physiology: endocrinology and metabolism (01.07.2016)
Published in American journal of physiology: endocrinology and metabolism (01.07.2016)
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Journal Article
Vascular Pool of Releasable Soluble VEGF Receptor-1 (sFLT1) in Women With Previous Preeclampsia and Uncomplicated Pregnancy
Weissgerber, Tracey L, Rajakumar, Augustine, Myerski, Ashley C, Edmunds, Lia R, Powers, Robert W, Roberts, James M, Gandley, Robin E, Hubel, Carl A
Published in The journal of clinical endocrinology and metabolism (01.03.2014)
Published in The journal of clinical endocrinology and metabolism (01.03.2014)
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Journal Article
Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis
Argemi, Josepmaria, Latasa, Maria U., Atkinson, Stephen R., Blokhin, Ilya O., Massey, Veronica, Gue, Joel P., Cabezas, Joaquin, Lozano, Juan J., Van Booven, Derek, Bell, Aaron, Cao, Sheng, Vernetti, Lawrence A., Arab, Juan P., Ventura-Cots, Meritxell, Edmunds, Lia R., Fondevila, Constantino, Stärkel, Peter, Dubuquoy, Laurent, Louvet, Alexandre, Odena, Gemma, Gomez, Juan L., Aragon, Tomas, Altamirano, Jose, Caballeria, Juan, Jurczak, Michael J., Taylor, D. Lansing, Berasain, Carmen, Wahlestedt, Claes, Monga, Satdarshan P., Morgan, Marsha Y., Sancho-Bru, Pau, Mathurin, Philippe, Furuya, Shinji, Lackner, Carolin, Rusyn, Ivan, Shah, Vijay H., Thursz, Mark R., Mann, Jelena, Avila, Matias A., Bataller, Ramon
Published in Nature communications (16.07.2019)
Published in Nature communications (16.07.2019)
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Journal Article
Abstract B25: Novel hepatic phenotypes caused by conditional c-Myc deletion
Edmunds, Lia R., Sharma, Lokendra, Otero, Peter Anthony, D'Souza, Sonia, Dolezal, James M., Zeng, Xuemei, Ding, Ying, Ding, Fei, Beck, Megan E., Kratz, Lisa E., Vockley, Jerry, Goetzman, Eric, Scott, Donald, Yates, Nathan, Duncan, Andrew W., Prochownik, Edward V.
Published in Molecular cancer research (01.01.2016)
Published in Molecular cancer research (01.01.2016)
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Journal Article