Notch Inhibition Induces Cochlear Hair Cell Regeneration and Recovery of Hearing after Acoustic Trauma
Mizutari, Kunio, Fujioka, Masato, Hosoya, Makoto, Bramhall, Naomi, Okano, Hirotaka James, Okano, Hideyuki, Edge, Albert S.B.
Published in Neuron (Cambridge, Mass.) (09.01.2013)
Published in Neuron (Cambridge, Mass.) (09.01.2013)
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Journal Article
Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery
Rees, Holly A., Komor, Alexis C., Yeh, Wei-Hsi, Caetano-Lopes, Joana, Warman, Matthew, Edge, Albert S. B., Liu, David R.
Published in Nature communications (06.06.2017)
Published in Nature communications (06.06.2017)
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In vivo base editing of post-mitotic sensory cells
Yeh, Wei-Hsi, Chiang, Hao, Rees, Holly A., Edge, Albert S. B., Liu, David R.
Published in Nature communications (05.06.2018)
Published in Nature communications (05.06.2018)
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Journal Article
Wnt-responsive Lgr5-expressing stem cells are hair cell progenitors in the cochlea
Shi, Fuxin, Kempfle, Judith S, Edge, Albert S B
Published in The Journal of neuroscience (11.07.2012)
Published in The Journal of neuroscience (11.07.2012)
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Clonal Expansion of Lgr5-Positive Cells from Mammalian Cochlea and High-Purity Generation of Sensory Hair Cells
McLean, Will J., Yin, Xiaolei, Lu, Lin, Lenz, Danielle R., McLean, Dalton, Langer, Robert, Karp, Jeffrey M., Edge, Albert S.B.
Published in Cell reports (Cambridge) (21.02.2017)
Published in Cell reports (Cambridge) (21.02.2017)
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A phase I/IIa safety and efficacy trial of intratympanic gamma-secretase inhibitor as a regenerative drug treatment for sensorineural hearing loss
Schilder, Anne G. M., Wolpert, Stephan, Saeed, Shakeel, Middelink, Leonie M., Edge, Albert S. B., Blackshaw, Helen, Pastiadis, Kostas, Bibas, Athanasios G.
Published in Nature communications (01.03.2024)
Published in Nature communications (01.03.2024)
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β-Catenin is required for hair-cell differentiation in the cochlea
Shi, Fuxin, Hu, Lingxiang, Jacques, Bonnie E, Mulvaney, Joanna F, Dabdoub, Alain, Edge, Albert S B
Published in The Journal of neuroscience (07.05.2014)
Published in The Journal of neuroscience (07.05.2014)
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An antibody to RGMa promotes regeneration of cochlear synapses after noise exposure
Nevoux, Jerome, Alexandru, Mihaela, Bellocq, Thomas, Tanaka, Lei, Hayashi, Yushi, Watabe, Takahisa, Lahlou, Hanae, Tani, Kohsuke, Edge, Albert S. B.
Published in Scientific reports (03.02.2021)
Published in Scientific reports (03.02.2021)
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Manipulating cell fate in the cochlea: a feasible therapy for hearing loss
Fujioka, Masato, Okano, Hideyuki, Edge, Albert S.B
Published in Trends in neurosciences (Regular ed.) (01.03.2015)
Published in Trends in neurosciences (Regular ed.) (01.03.2015)
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Altered expression of genes regulating inflammation and synaptogenesis during regrowth of afferent neurons to cochlear hair cells
Wu, Chen-Chi, Brugeaud, Aurore, Seist, Richard, Lin, Hsiao-Chun, Yeh, Wei-Hsi, Petrillo, Marco, Coppola, Giovanni, Edge, Albert S B, Stankovic, Konstantina M
Published in PloS one (01.10.2020)
Published in PloS one (01.10.2020)
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Sox2 in the differentiation of cochlear progenitor cells
Kempfle, Judith S., Turban, Jack L., Edge, Albert S. B.
Published in Scientific reports (18.03.2016)
Published in Scientific reports (18.03.2016)
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Diphtheria Toxin-Induced Cell Death Triggers Wnt-Dependent Hair Cell Regeneration in Neonatal Mice
Hu, Lingxiang, Lu, Jingrong, Chiang, Hao, Wu, Hao, Edge, Albert S B, Shi, Fuxin
Published in The Journal of neuroscience (07.09.2016)
Published in The Journal of neuroscience (07.09.2016)
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