MutLγ promotes repeat expansion in a Fragile X mouse model while EXO1 is protective
Zhao, Xiaonan, Zhang, Yongwei, Wilkins, Kenneth, Edelmann, Winfried, Usdin, Karen
Published in PLoS genetics (01.10.2018)
Published in PLoS genetics (01.10.2018)
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Molecular structures and mechanisms of DNA break processing in mouse meiosis
Yamada, Shintaro, Hinch, Anjali Gupta, Kamido, Hisashi, Zhang, Yongwei, Edelmann, Winfried, Keeney, Scott
Published in Genes & development (01.06.2020)
Published in Genes & development (01.06.2020)
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Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells
Belcheva, Antoaneta, Irrazabal, Thergiory, Robertson, Susan J., Streutker, Catherine, Maughan, Heather, Rubino, Stephen, Moriyama, Eduardo H., Copeland, Julia K., Surendra, Anu, Kumar, Sachin, Green, Blerta, Geddes, Kaoru, Pezo, Rossanna C., Navarre, William W., Milosevic, Michael, Wilson, Brian C., Girardin, Stephen E., Wolever, Thomas M.S., Edelmann, Winfried, Guttman, David S., Philpott, Dana J., Martin, Alberto
Published in Cell (17.07.2014)
Published in Cell (17.07.2014)
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H1 histones control the epigenetic landscape by local chromatin compaction
Willcockson, Michael A., Healton, Sean E., Weiss, Cary N., Bartholdy, Boris A., Botbol, Yair, Mishra, Laxmi N., Sidhwani, Dhruv S., Wilson, Tommy J., Pinto, Hugo B., Maron, Maxim I., Skalina, Karin A., Toro, Laura Norwood, Zhao, Jie, Lee, Chul-Hwan, Hou, Harry, Yusufova, Nevin, Meydan, Cem, Osunsade, Adewola, David, Yael, Cesarman, Ethel, Melnick, Ari M., Sidoli, Simone, Garcia, Benjamin A., Edelmann, Winfried, Macian, Fernando, Skoultchi, Arthur I.
Published in Nature (London) (14.01.2021)
Published in Nature (London) (14.01.2021)
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Blockade of the immunosuppressive KIR2DL5/PVR pathway elicits potent human NK cell–mediated antitumor immunity
Ren, Xiaoxin, Peng, Mou, Xing, Peng, Wei, Yao, Galbo, Phillip M., Corrigan, Devin, Wang, Hao, Su, Yingzhen, Dong, Xiaoshen, Sun, Qizhe, Li, Yixian, Zhang, Xiaoyu, Edelmann, Winfried, Zheng, Deyou, Zang, Xingxing
Published in The Journal of clinical investigation (15.11.2022)
Published in The Journal of clinical investigation (15.11.2022)
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The ISWI ATPase Smarca5 (Snf2h) Is Required for Proliferation and Differentiation of Hematopoietic Stem and Progenitor Cells
Kokavec, Juraj, Zikmund, Tomas, Savvulidi, Filipp, Kulvait, Vojtech, Edelmann, Winfried, Skoultchi, Arthur I., Stopka, Tomas
Published in Stem cells (Dayton, Ohio) (01.06.2017)
Published in Stem cells (Dayton, Ohio) (01.06.2017)
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Minimal PU.1 reduction induces a preleukemic state and promotes development of acute myeloid leukemia
Will, Britta, Vogler, Thomas O, Narayanagari, Swathi, Bartholdy, Boris, Todorova, Tihomira I, da Silva Ferreira, Mariana, Chen, Jiahao, Yu, Yiting, Mayer, Jillian, Barreyro, Laura, Carvajal, Luis, Neriah, Daniela Ben, Roth, Michael, van Oers, Johanna, Schaetzlein, Sonja, McMahon, Christine, Edelmann, Winfried, Verma, Amit, Steidl, Ulrich
Published in Nature medicine (01.10.2015)
Published in Nature medicine (01.10.2015)
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Genome Replication Is Associated With Release of Immunogenic DNA Waste
Schubert, Nadja, Schumann, Tina, Daum, Elena, Flade, Karolin, Ge, Yan, Hagedorn, Lara, Edelmann, Winfried, Müller, Luise, Schmitz, Marc, Kuut, Gunnar, Hornung, Veit, Behrendt, Rayk, Roers, Axel
Published in Frontiers in immunology (11.05.2022)
Published in Frontiers in immunology (11.05.2022)
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The Transcriptomic Landscape of Mismatch Repair-Deficient Intestinal Stem Cells
Bommi, Prashant V, Bowen, Charles M, Reyes-Uribe, Laura, Wu, Wenhui, Katayama, Hiroyuki, Rocha, Pedro, Parra, Edwin R, Francisco-Cruz, Alejandro, Ozcan, Zuhal, Tosti, Elena, Willis, Jason A, Wu, Hong, Taggart, Melissa W, Burks, Jared K, Lynch, Patrick M, Edelmann, Winfried, Scheet, Paul A, Wistuba, Ignacio I, Sinha, Krishna M, Hanash, Samir M, Vilar, Eduardo
Published in Cancer research (Chicago, Ill.) (15.05.2021)
Published in Cancer research (Chicago, Ill.) (15.05.2021)
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Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation
He, Shuying, Limi, Saima, McGreal, Rebecca S, Xie, Qing, Brennan, Lisa A, Kantorow, Wanda Lee, Kokavec, Juraj, Majumdar, Romit, Hou, Jr, Harry, Edelmann, Winfried, Liu, Wei, Ashery-Padan, Ruth, Zavadil, Jiri, Kantorow, Marc, Skoultchi, Arthur I, Stopka, Tomas, Cvekl, Ales
Published in Development (Cambridge) (01.06.2016)
Published in Development (Cambridge) (01.06.2016)
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Intergenerational and striatal CAG repeat instability in Huntington's disease knock-in mice involve different DNA repair genes
Dragileva, Ella, Hendricks, Audrey, Teed, Allison, Gillis, Tammy, Lopez, Edith T, Friedberg, Errol C, Kucherlapati, Raju, Edelmann, Winfried, Lunetta, Kathryn L, MacDonald, Marcy E, Wheeler, Vanessa C
Published in Neurobiology of disease (01.01.2009)
Published in Neurobiology of disease (01.01.2009)
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Mammalian Exo1 encodes both structural and catalytic functions that play distinct roles in essential biological processes
Schaetzlein, Sonja, Chahwan, Richard, Avdievich, Elena, Roa, Sergio, Wei, Kaichun, Eoff, Robert L, Sellers, Rani S, Clark, Alan B, Kunkel, Thomas A, Scharff, Matthew D, Edelmann, Winfried
Published in Proceedings of the National Academy of Sciences - PNAS (02.07.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (02.07.2013)
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Detection of coding microsatellite frameshift mutations in DNA mismatch repair-deficient mouse intestinal tumors
Woerner, Stefan M., Tosti, Elena, Yuan, Yan P., Kloor, Matthias, Bork, Peer, Edelmann, Winfried, Gebert, Johannes
Published in Molecular carcinogenesis (01.11.2015)
Published in Molecular carcinogenesis (01.11.2015)
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A functional cancer genomics screen identifies a druggable synthetic lethal interaction between MSH3 and PRKDC
Dietlein, Felix, Thelen, Lisa, Jokic, Mladen, Jachimowicz, Ron D, Ivan, Laura, Knittel, Gero, Leeser, Uschi, van Oers, Johanna, Edelmann, Winfried, Heukamp, Lukas C, Reinhardt, H Christian
Published in Cancer discovery (01.05.2014)
Published in Cancer discovery (01.05.2014)
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Genomic Landscape of Colorectal Mucosa and Adenomas
Borras, Ester, San Lucas, F Anthony, Chang, Kyle, Zhou, Ruoji, Masand, Gita, Fowler, Jerry, Mork, Maureen E, You, Y Nancy, Taggart, Melissa W, McAllister, Florencia, Jones, David A, Davies, Gareth E, Edelmann, Winfried, Ehli, Erik A, Lynch, Patrick M, Hawk, Ernest T, Capella, Gabriel, Scheet, Paul, Vilar, Eduardo
Published in Cancer prevention research (Philadelphia, Pa.) (01.06.2016)
Published in Cancer prevention research (Philadelphia, Pa.) (01.06.2016)
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MSH2 ATPase Domain Mutation Affects CTG•CAG Repeat Instability in Transgenic Mice
Tomé, Stéphanie, Holt, Ian, Edelmann, Winfried, Morris, Glenn E., Munnich, Arnold, Pearson, Christopher E., Gourdon, Geneviève
Published in PLoS genetics (15.05.2009)
Published in PLoS genetics (15.05.2009)
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(CAG) n -hairpin DNA binds to Msh2-Msh3 and changes properties of mismatch recognition
McMurray, Cynthia T, Owen, Barbara A L, Yang, Zungyoon, Lai, Maoyi, Gajek, Maciez, Badger, John D, Hayes, Jeffrey J, Edelmann, Winfried, Kucherlapati, Raju, Wilson, Teresa M
Published in Nature structural & molecular biology (01.08.2005)
Published in Nature structural & molecular biology (01.08.2005)
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