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Optimization of Pan-Pim Kinase Activity and Oral Bioavailability Leading to Diaminopyrazole (GDC-0339) for the Treatment of Multiple Myeloma
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Therapeutic potential of an anti-CD79b antibody–drug conjugate, anti–CD79b-vc-MMAE, for the treatment of non-Hodgkin lymphoma
Dornan, David, Bennett, Fiona, Chen, Yvonne, Dennis, Mark, Eaton, Dan, Elkins, Kristi, French, Dorothy, Go, Mary Ann T., Jack, Andrew, Junutula, Jagath R., Koeppen, Hartmut, Lau, Jeffrey, McBride, Jacqueline, Rawstron, Andy, Shi, Xiaoyan, Yu, Nancy, Yu, Shang-Fan, Yue, Peng, Zheng, Bing, Ebens, Allen, Polson, Andrew G.
Published in Blood (24.09.2009)
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Discovery of novel pyrazolo[1,5-a]pyrimidines as potent pan-Pim inhibitors by structure- and property-based drug design
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Published in Bioorganic & medicinal chemistry letters (01.06.2013)
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Discovery of 5‑Azaindazole (GNE-955) as a Potent Pan-Pim Inhibitor with Optimized Bioavailability
Wang, Xiaojing, Kolesnikov, Aleksandr, Tay, Suzanne, Chan, Grace, Chao, Qi, Do, Steven, Drummond, Jason, Ebens, Allen J, Liu, Ning, Ly, Justin, Harstad, Eric, Hu, Huiyong, Moffat, John, Munugalavadla, Veerendra, Murray, Jeremy, Slaga, Dionysos, Tsui, Vickie, Volgraf, Matthew, Wallweber, Heidi, Chang, Jae H
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The Pim-1 Protein Kinase Is an Important Regulator of MET Receptor Tyrosine Kinase Levels and Signaling
Cen, Bo, Xiong, Ying, Song, Jin H., Mahajan, Sandeep, DuPont, Rachel, McEachern, Kristen, DeAngelo, Daniel J., Cortes, Jorge E., Minden, Mark D., Ebens, Allen, Mims, Alice, LaRue, Amanda C., Kraft, Andrew S.
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Published in Molecular and cellular biology (01.07.2014)
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Antibody-Drug Conjugates for the Treatment of Non-Hodgkin's Lymphoma: Target and Linker-Drug Selection
POLSON, Andrew G, CALEMINE-FENAUX, Jill, FRANTZ, Gretchen, FUJI, Reina N, GRAY, Alane, HARDEN, Kristin, INGLE, Gladys S, KLJAVIN, Noelyn M, KOEPPEN, Hartmut, NELSON, Christopher, PRABHU, Saileta, RAAB, Helga, CHAN, Pamela, ROSS, Sarajane, STEPHAN, Jean-Philippe, SCALES, Suzie J, SPENCER, Susan D, VANDLEN, Richard, WRANIK, Bernd, YU, Shang-Fan, BING ZHENG, EBENS, Allen, CHANG, Wesley, CHRISTENSEN, Erin, CLARK, Suzanna, DE SAUVAGE, Frederic J, EATON, Dan, ELKINS, Kristi, ELLIOTT, J. Michael
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Expression pattern of the human FcRH/IRTA receptors in normal tissue and in B-chronic lymphocytic leukemia
Polson, Andrew G., Zheng, Bing, Elkins, Kristi, Chang, Wesley, Du, Changchun, Dowd, Patrick, Yen, Lulu, Tan, Christine, Hongo, Jo-Anne, Koeppen, Hartmut, Ebens, Allen
Published in International immunology (01.09.2006)
Published in International immunology (01.09.2006)
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Cathepsin B Nuclear Flux in a DNA-Guided “Antinuclear Missile” Cancer Therapy
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Published in ACS central science (28.08.2024)
Published in ACS central science (28.08.2024)
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Antibody-drug conjugates targeted to CD79 for the treatment of non-Hodgkin lymphoma
Polson, Andrew G., Yu, Shang-Fan, Elkins, Kristi, Zheng, Bing, Clark, Suzanna, Ingle, Gladys S., Slaga, Dionysos S., Giere, Lynne, Du, Changchun, Tan, Christine, Hongo, Jo-Anne, Gogineni, Alvin, Cole, Mary J., Vandlen, Richard, Stephan, Jean-Philippe, Young, Judy, Chang, Wesley, Scales, Suzie J., Ross, Sarajane, Eaton, Dan, Ebens, Allen
Published in Blood (15.07.2007)
Published in Blood (15.07.2007)
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In vivo effects of targeting CD79b with antibodies and antibody-drug conjugates
Zheng, Bing, Fuji, Reina N, Elkins, Kristi, Yu, Shang-Fan, Fuh, Franklin K, Chuh, Josefa, Tan, Christine, Hongo, Jo-Anne, Raab, Helga, Kozak, Katherine R, Williams, Marna, McDorman, Elena, Eaton, Dan, Ebens, Allen, Polson, Andrew G
Published in Molecular cancer therapeutics (01.10.2009)
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Anti-BR3 antibodies: a new class of B-cell immunotherapy combining cellular depletion and survival blockade
Lin, Wei Yu, Gong, Qian, Seshasayee, Dhaya, Lin, Zhonghua, Ou, Qinglin, Ye, Shiming, Suto, Eric, Shu, Jean, Pun Lee, Wyne, Lee, Ching-Wei V., Fuh, Germaine, Leabman, Maya, Iyer, Suhasini, Howell, Kathy, Gelzleichter, Thomas, Beyer, Joseph, Danilenko, Dimitry, Yeh, Sherry, DeForge, Laura E., Ebens, Allen, Thompson, Jeffrey S., Ambrose, Christine, Balazs, Mercedesz, Starovasnik, Melissa A., Martin, Flavius
Published in Blood (01.12.2007)
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Hepatocyte Growth Factor/Scatter Factor Is an Axonal Chemoattractant and a Neurotrophic Factor for Spinal Motor Neurons
Ebens, Allen, Brose, Katja, Leonardo, E.David, Jr, M.Gartz Hanson, Bladt, Friedhelm, Birchmeier, Carmen, Barres, Barbara A, Tessier-Lavigne, Marc
Published in Neuron (Cambridge, Mass.) (01.12.1996)
Published in Neuron (Cambridge, Mass.) (01.12.1996)
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An integrative biology approach for analysis of drug action in models of human vascular inflammation
Kunkel, Eric J, Dea, Marlene, Ebens, Allen, Hytopoulos, Evangelos, Melrose, Jennifer, Nguyen, Dat, Ota, Ken S, Plavec, Ivan, Wang, Yuker, Watson, Susan R, Butcher, Eugene C, Berg, Ellen L
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Published in The FASEB journal (01.08.2004)
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Human Semaphorin K1 Is Glycosylphosphatidylinositol-linked and Defines a New Subfamily of Viral-related Semaphorins
Xu, Xiaomei, Ng, Sheldon, Wu, Zhi-Liang, Nguyen, Dat, Homburger, Sheila, Seidel-Dugan, Cynthia, Ebens, Allen, Luo, Yuling
Published in The Journal of biological chemistry (28.08.1998)
Published in The Journal of biological chemistry (28.08.1998)
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Antitumor efficacy of a bispecific antibody that targets HER2 and activates T cells
Junttila, Teemu T, Li, Ji, Johnston, Jennifer, Hristopoulos, Maria, Clark, Robyn, Ellerman, Diego, Wang, Bu-Er, Li, Yijin, Mathieu, Mary, Li, Guangmin, Young, Judy, Luis, Elizabeth, Lewis Phillips, Gail, Stefanich, Eric, Spiess, Christoph, Polson, Andrew, Irving, Bryan, Scheer, Justin M, Junttila, Melissa R, Dennis, Mark S, Kelley, Robert, Totpal, Klara, Ebens, Allen
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Mutations disrupting neuronal connectivity in the Drosophila visual system
Martin, Kathleen A, Poeck, Burkhard, Roth, Helmut, Ebens, Allen J, Ballard, Linda Conley, Zipursky, S.Lawrence
Published in Neuron (Cambridge, Mass.) (01.02.1995)
Published in Neuron (Cambridge, Mass.) (01.02.1995)
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