An in Silico Method for Predicting Ames Activities of Primary Aromatic Amines by Calculating the Stabilities of Nitrenium Ions
Bentzien, Jörg, Hickey, Eugene R, Kemper, Raymond A, Brewer, Mark L, Dyekjær, Jane D, East, Stephen P, Whittaker, Mark
Published in Journal of chemical information and modeling (22.02.2010)
Published in Journal of chemical information and modeling (22.02.2010)
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Journal Article
Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ
Czaplewski, Lloyd G., Collins, Ian, Boyd, E. Andrew, Brown, David, East, Stephen P., Gardiner, Mihaly, Fletcher, Rowena, Haydon, David J., Henstock, Vincent, Ingram, Peter, Jones, Clare, Noula, Caterina, Kennison, Leanne, Rockley, Chris, Rose, Valerie, Thomaides-Brears, Helena B., Ure, Rebecca, Whittaker, Mark, Stokes, Neil R.
Published in Bioorganic & medicinal chemistry letters (15.01.2009)
Published in Bioorganic & medicinal chemistry letters (15.01.2009)
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Journal Article
Peptidomimetic inhibitors of bacterial peptide deformylase
East, Stephen P, Ayscough, Andrew, Toogood-Johnson, Ian, Taylor, Steven, Thomas, Wayne
Published in Bioorganic & medicinal chemistry letters (01.07.2011)
Published in Bioorganic & medicinal chemistry letters (01.07.2011)
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Journal Article
DNA gyrase (GyrB)/topoisomerase IV (ParE) inhibitors: Synthesis and antibacterial activity
East, Stephen P., White, Clara Bantry, Barker, Oliver, Barker, Stephanie, Bennett, James, Brown, David, Boyd, E. Andrew, Brennan, Christopher, Chowdhury, Chandana, Collins, Ian, Convers-Reignier, Emmanuelle, Dymock, Brian W., Fletcher, Rowena, Haydon, David J., Gardiner, Mihaly, Hatcher, Stuart, Ingram, Peter, Lancett, Paul, Mortenson, Paul, Papadopoulos, Konstantinos, Smee, Carol, Thomaides-Brears, Helena B., Tye, Heather, Workman, James, Czaplewski, Lloyd G.
Published in Bioorganic & medicinal chemistry letters (01.02.2009)
Published in Bioorganic & medicinal chemistry letters (01.02.2009)
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Journal Article
Arylsulfonamide CB2 receptor agonists: SAR and optimization of CB2 selectivity
Ermann, Monika, Riether, Doris, Walker, Edward R., Mushi, Innocent F., Jenkins, James E., Noya-Marino, Beatriz, Brewer, Mark L., Taylor, Malcolm G., Amouzegh, Patricia, East, Stephen P., Dymock, Brian W., Gemkow, Mark J., Kahrs, Andreas F., Ebneth, Andreas, Löbbe, Sabine, O’Shea, Kathy, Shih, Daw-Tsun, Thomson, David
Published in Bioorganic & medicinal chemistry (01.03.2008)
Published in Bioorganic & medicinal chemistry (01.03.2008)
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Journal Article
Application of a 5-endo-trig cyclisation in the total synthesis of (+)-preussin
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Journal Article
Web Resource
An orally bioavailable positive allosteric modulator of the mGlu4 receptor with efficacy in an animal model of motor dysfunction
EAST, Stephen P, BAMFORD, Samantha, PUI LOKE, SCHÄNZLE, Gerhard, SCHUBERT, Hans-Dieter, SCOTT, John, WHITTAKER, Mark, WILLIAMS, Mildred, ZAWADZKI, Przemyslaw, GERLACH, Kai, DIETZ, Matthias G. A, EICKMEIER, Christian, FLEGG, Adam, FERGER, Boris, GEMKOW, Mark J, HEILKER, Ralf, HENGERER, Bastian, KOTEY, Adrian
Published in Bioorganic & medicinal chemistry letters (15.08.2010)
Published in Bioorganic & medicinal chemistry letters (15.08.2010)
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Journal Article
Structure–activity relationships of the peptide deformylase inhibitor BB-3497: modification of the metal binding group
Smith, Helen K., Beckett, R.Paul, Clements, John M., Doel, Sheila, East, Stephen P., Launchbury, Steven B., Pratt, Lisa M., Spavold, Zoë M., Thomas, Wayne, Todd, Richard S., Whittaker, Mark
Published in Bioorganic & medicinal chemistry letters (16.12.2002)
Published in Bioorganic & medicinal chemistry letters (16.12.2002)
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Journal Article
Peptide deformylase inhibitors with activity against respiratory tract pathogens
East, Stephen P, Beckett, R.Paul, Brookings, Daniel C, Clements, John M, Doel, Sheila, Keavey, Kenneth, Pain, Gilles, Smith, Helen K, Thomas, Wayne, Thompson, Alison J, Todd, Richard S, Whittaker, Mark
Published in Bioorganic & medicinal chemistry letters (05.01.2004)
Published in Bioorganic & medicinal chemistry letters (05.01.2004)
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Journal Article
An orally bioavailable positive allosteric modulator of the mGlu 4 receptor with efficacy in an animal model of motor dysfunction
East, Stephen P., Bamford, Samantha, Dietz, Matthias G.A., Eickmeier, Christian, Flegg, Adam, Ferger, Boris, Gemkow, Mark J., Heilker, Ralf, Hengerer, Bastian, Kotey, Adrian, Loke, Pui, Schänzle, Gerhard, Schubert, Hans-Dieter, Scott, John, Whittaker, Mark, Williams, Mildred, Zawadzki, Przemyslaw, Gerlach, Kai
Published in Bioorganic & medicinal chemistry letters (15.08.2010)
Published in Bioorganic & medicinal chemistry letters (15.08.2010)
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Journal Article
An orally bioavailable positive allosteric modulator of the mGlu sub(4) receptor with efficacy in an animal model of motor dysfunction
East, Stephen P, Bamford, Samantha, Dietz, Matthias GA, Eickmeier, Christian, Flegg, Adam, Ferger, Boris, Gemkow, Mark J, Heilker, Ralf, Hengerer, Bastian, Kotey, Adrian, Loke, Pui, Schaenzle, Gerhard, Schubert, Hans-Dieter, Scott, John, Whittaker, Mark, Williams, Mildred, Zawadzki, Przemyslaw, Gerlach, Kai
Published in Bioorganic & medicinal chemistry letters (15.08.2010)
Published in Bioorganic & medicinal chemistry letters (15.08.2010)
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Journal Article
Construction of Fused Medium-Ring Carbocycles by Catalytic Generation and Rearrangement of Oxonium Ylides
Clark, J. Stephen, Walls, Steven B., Wilson, Claire, East, Stephen P., Drysdale, Martin J.
Published in European Journal of Organic Chemistry (01.01.2006)
Published in European Journal of Organic Chemistry (01.01.2006)
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Book Review
Journal Article
Corrigendum to “DNA gyrase (GyrB)/topoisomerase IV (ParE) inhibitors: Synthesis and antibacterial activity” [Bioorg. Med. Chem. Lett. 19 (2009) 894]
East, Stephen P., Bantry White, Clara, Barker, Oliver, Barker, Stephanie, Bennett, James, Brown, David, Andrew Boyd, E., Brennan, Christopher, Chowdhury, Chandana, Collins, Ian, Convers-Reignier, Emmanuelle, Dymock, Brian W., Fletcher, Rowena, Haydon, David J., Gardiner, Mihaly, Hatcher, Stuart, Ingram, Peter, Lancett, Paul, Mortenson, Paul, Papadopoulos, Konstantinos, Smee, Carol, Thomaides-Brears, Helena B., Tye, Heather, Workman, James, Czaplewski, Lloyd G.
Published in Bioorganic & medicinal chemistry letters (01.05.2009)
Published in Bioorganic & medicinal chemistry letters (01.05.2009)
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Journal Article
Corrigendum: Corrigendum to 'DNA gyrase (GyrB)/topoisomerase IV (ParE) inhibitors: Synthesis and antibacterial activity' [Bioorg. Med. Chem. Lett. 19 (2009) 894]
East, Stephen P, White, Clara Bantry, Barker, Oliver, Barker, Stephanie, Bennett, James, Brown, David, Boyd, E Andrew, Brennan, Christopher, Chowdhury, Chandana, Collins, Ian, Convers-Reignier, Emmanuelle, Dymock, Brian W, Fletcher, Rowena, Haydon, David J, Gardiner, Mihaly, Hatcher, Stuart, Ingram, Peter, Lancett, Paul, Mortenson, Paul, Papadopoulos, Konstantinos, Smee, Carol, Thomaides-Brears, Helena B, Tye, Heather, Workman, James, Czaplewski, Lloyd G
Published in Bioorganic & medicinal chemistry letters (01.05.2009)
Published in Bioorganic & medicinal chemistry letters (01.05.2009)
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Journal Article