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Discovery and development of CPL207280 as new GPR40/FFA1 agonist

Discovery and development of CPL207280 as new GPR40/FFA1 agonist

by Mach, Mateusz, Bazydło-Guzenda, Katarzyna, Buda, Paweł, Matłoka, Mikołaj, Dzida, Radosław, Stelmach, Filip, Gałązka, Kinga, Wąsińska-Kałwa, Małgorzata, Smuga, Damian, Hołowińska, Dagmara, Dawid, Urszula, Gurba-Bryśkiewicz, Lidia, Wiśniewski, Krzysztof, Dubiel, Krzysztof, Pieczykolan, Jerzy, Wieczorek, Maciej
Published in European journal of medicinal chemistry (15.12.2021)

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Journal Article

Discovery of CPL207-280CA, an Effective and Safe GPR40 Agonist for the Treatment of Type 2 Diabetes

Discovery of CPL207-280CA, an Effective and Safe GPR40 Agonist for the Treatment of Type 2 Diabetes

by BAZYDLO, KATARZYNA, BUDA, PAWEL, MACH, MATEUSZ, DZIDA, RADOSłAW, STELMACH, FILIP, DUBIEL, KRZYSZTOF K., PIECZYKOLAN, JERZY S., WIECZOREK, MACIEJ
Published in Diabetes (New York, N.Y.) (01.07.2018)

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Journal Article

CPL207280, a Novel G Protein–Coupled Receptor 40/Free Fatty Acid Receptor 1–Specific Agonist, Shows a Favorable Safety Profile and Exerts Antidiabetic Effects in Type 2 Diabetic Animals

by Bazydlo-Guzenda, Katarzyna, Buda, Pawel, Matloka, Mikolaj, Mach, Mateusz, Stelmach, Filip, Dzida, Radoslaw, Smuga, Damian, Hucz-Kalitowska, Joanna, Teska-Kaminska, Malgorzata, Vialichka, Varvara, Dubiel, Krzysztof, Kaminska, Bozena, Wieczorek, Maciej, Pieczykolan, Jerzy
Published in Molecular pharmacology (01.10.2021)

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Journal Article

3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS

3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS

by DZIDA, RADOSŁAW, DUBIEL, KRZYSZTOF, SMUGA, DAMIAN, WIECZOREK, MACIEJ, MACH, MATEUSZ, STELMACH, FILIP, MATŁOKA, MIKOŁAJ, PIECZYKOLAN, JERZY, BAZYDŁO, KATARZYNA
Year of Publication 08.05.2023

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Patent

Derivatives of 3-phenyl-4-hexynoic acid as GPR40 agonists

Derivatives of 3-phenyl-4-hexynoic acid as GPR40 agonists

by DZIDA, RADOSŁAW, DUBIEL, KRZYSZTOF, SMUGA, DAMIAN, WIECZOREK, MACIEJ, MACH, MATEUSZ, STELMACH, FILIP, MATŁOKA, MIKOŁAJ, PIECZYKOLAN, JERZY, BAZYDŁO, KATARZYNA
Year of Publication 15.07.2019

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Patent

Derivados del ácido 3-fenil-4-hexinoico como agonistas de GPR40

Derivados del ácido 3-fenil-4-hexinoico como agonistas de GPR40

by MACH, Mateusz, SMUGA, Damian, STELMACH, Filip, DUBIEL, Krzysztof, DZIDA, Radoslaw, PIECZYKOLAN, Jerzy, MATLOKA, Mikolaj, BAZYDLO, Katarzyna, WIECZOREK, Maciej
Year of Publication 04.06.2024

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Patent

3-PHENYL-4-HEXYNSYREDERIVATER SOM GPR40-AGONISTER

3-PHENYL-4-HEXYNSYREDERIVATER SOM GPR40-AGONISTER

by MACH, Mateusz, SMUGA, Damian, STELMACH, Filip, DUBIEL, Krzysztof, DZIDA, Radoslaw, PIECZYKOLAN, Jerzy, MATLOKA, Mikolaj, BAZYDLO, Katarzyna, WIECZOREK, Maciej
Year of Publication 27.05.2024

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Patent

3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS

3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS

by MACH, Mateusz, SMUGA, Damian, STELMACH, Filip, DUBIEL, Krzysztof, DZIDA, Radoslaw, PIECZYKOLAN, Jerzy, MATLOKA, Mikolaj, BAZYDLO, Katarzyna, WIECZOREK, Maciej
Year of Publication 15.05.2024

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Patent

3-phenyl-4-hexynoic acid derivatives as GPR40 agonists

3-phenyl-4-hexynoic acid derivatives as GPR40 agonists

by Matloka, Mikolaj, Bazydlo, Katarzyna, Dzida, Radoslaw, Dubiel, Krzysztof, Pieczykolan, Jerzy, Mach, Mateusz, Wieczorek, Maciej, Stelmach, Filip, Smuga, Damian
Year of Publication 23.04.2024

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Patent

3-phenyl-4-hexynoic acid derivatives as GPR40 agonists

3-phenyl-4-hexynoic acid derivatives as GPR40 agonists

by MACH, Mateusz, SMUGA, Damian, STELMACH, Filip, DUBIEL, Krzysztof, DZIDA, Radoslaw, PIECZYKOLAN, Jerzy, MATLOKA, Mikolaj, BAZYDLO, Katarzyna, WIECZOREK, Maciej
Year of Publication 07.03.2024

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Patent

3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS

3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS

by MACH, Mateusz, SMUGA, Damian, STELMACH, Filip, DUBIEL, Krzysztof, DZIDA, Radoslaw, PIECZYKOLAN, Jerzy, MATLOKA, Mikolaj, BAZYDLO, Katarzyna, WIECZOREK, Maciej
Year of Publication 19.03.2023

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Patent

3-PHENYL-4-HEXYNSYREDERIVATER SOM GPR40-AGONISTER

3-PHENYL-4-HEXYNSYREDERIVATER SOM GPR40-AGONISTER

by MACH, Mateusz, SMUGA, Damian, STELMACH, Filip, DUBIEL, Krzysztof, DZIDA, Radoslaw, PIECZYKOLAN, Jerzy, MATLOKA, Mikolaj, BAZYDLO, Katarzyna, WIECZOREK, Maciej
Year of Publication 13.03.2023

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Patent

3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS

3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS

by MACH, Mateusz, SMUGA, Damian, STELMACH, Filip, DUBIEL, Krzysztof, DZIDA, Radoslaw, PIECZYKOLAN, Jerzy, MATLOKA, Mikolaj, BAZYDLO, Katarzyna, WIECZOREK, Maciej
Year of Publication 14.12.2022

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Patent

3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS

3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS

by MACH, Mateusz, SMUGA, Damian, STELMACH, Filip, DUBIEL, Krzysztof, DZIDA, Radoslaw, PIECZYKOLAN, Jerzy, MATLOKA, Mikolaj, BAZYDLO, Katarzyna, WIECZOREK, Maciej
Year of Publication 24.12.2020

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Patent

3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS

3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS

by MACH, Mateusz, SMUGA, Damian, STELMACH, Filip, DUBIEL, Krzysztof, DZIDA, Radoslaw, PIECZYKOLAN, Jerzy, MATLOKA, Mikolaj, BAZYDLO, Katarzyna, WIECZOREK, Maciej
Year of Publication 18.11.2020

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Patent

3-phenyl-4-hexynoic acid derivatives as GPR40 agonists

3-phenyl-4-hexynoic acid derivatives as GPR40 agonists

by MACH, Mateusz, SMUGA, Damian, STELMACH, Filip, DUBIEL, Krzysztof, DZIDA, Radoslaw, PIECZYKOLAN, Jerzy, MATLOKA, Mikolaj, BAZYDLO, Katarzyna, WIECZOREK, Maciej
Year of Publication 16.07.2020

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Patent

3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS

3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS

by MATLOKA, MIKOLAJ, DUBIEL, KRZYSZTOF, SMUGA, DAMIAN, BAZYDLO, KATARZYNA, WIECZOREK, MACIEJ, MACH, MATEUSZ, DZIDA, RADOSLAW, STELMACH, FILIP, PIECZYKOLAN, JERZY
Year of Publication 11.07.2019

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Patent

3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS

3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS

by MACH, Mateusz, SMUGA, Damian, STELMACH, Filip, DUBIEL, Krzysztof, DZIDA, Radoslaw, PIECZYKOLAN, Jerzy, MATLOKA, Mikolaj, BAZYDLO, Katarzyna, WIECZOREK, Maciej
Year of Publication 11.07.2019

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Patent

Derivados del ácido 3-fenil-4-hexinoico como agonistas de GPR40

Derivados del ácido 3-fenil-4-hexinoico como agonistas de GPR40

by MACH, Mateusz, SMUGA, Damian, STELMACH, Filip, DUBIEL, Krzysztof, DZIDA, Radoslaw, PIECZYKOLAN, Jerzy, MATLOKA, Mikolaj, BAZYDLO, Katarzyna, WIECZOREK, Maciej
Year of Publication 26.04.2023

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Patent

derivados de ácido 3-fenil-4-hexinôico como agonistas gpr40

derivados de ácido 3-fenil-4-hexinôico como agonistas gpr40

by MATEUSZ MACH, FILIP STELMACH, JERZY PIECZYKOLAN, KATARZYNA BAZYDLO, MIKOLAJ MATLOKA, RADOSLAW DZIDA, DAMIAN SMUGA, KRZYSZTOF DUBIEL, MACIEJ WIECZOREK
Year of Publication 01.12.2020

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Patent