Epithelial–mesenchymal transition confers resistance to selective FGFR inhibitors in SNU-16 gastric cancer cells
Grygielewicz, Paulina, Dymek, Barbara, Bujak, Anna, Gunerka, Pawel, Stanczak, Aleksandra, Lamparska-Przybysz, Monika, Wieczorek, Maciej, Dzwonek, Karolina, Zdzalik, Daria
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01.01.2016)
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01.01.2016)
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Journal Article
Inhibition of CHIT1 as a novel therapeutic approach in idiopathic pulmonary fibrosis
Sklepkiewicz, Piotr, Dymek, Barbara A., Mlacki, Michal, Koralewski, Robert, Mazur, Marzena, Nejman-Gryz, Patrycja, Korur, Serdar, Zagozdzon, Agnieszka, Rymaszewska, Aleksandra, von der Thüsen, Jan H., Siwińska, Anna M., Güner, Nazan Cemre, Cheda, Łukasz, Paplinska-Goryca, Magdalena, Proboszcz, Małgorzata, van den Bosch, Thierry P.P., Górska, Katarzyna, Golab, Jakub, Kamiński, Rafał M., Krenke, Rafał, Golebiowski, Adam, Dzwonek, Karolina, Dobrzanski, Pawel
Published in European journal of pharmacology (15.03.2022)
Published in European journal of pharmacology (15.03.2022)
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Journal Article
Inhibition of Macrophage-Specific CHIT1 as an Approach to Treat Airway Remodeling in Severe Asthma
Sklepkiewicz, Piotr, Dymek, Barbara, Mlacki, Michal, Zagozdzon, Agnieszka, Salamon, Magdalena, Siwińska, Anna Maria, Mazurkiewicz, Marcin Piotr, de Souza Xavier Costa, Natalia, Mazur, Marzena, Mauad, Thais, Gołębiowski, Adam, Dzwonek, Karolina, Gołąb, Jakub, Zasłona, Zbigniew
Published in International journal of molecular sciences (01.03.2023)
Published in International journal of molecular sciences (01.03.2023)
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Journal Article
Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma
Mazur, Marzena, Olczak, Jacek, Olejniczak, Sylwia, Koralewski, Robert, Czestkowski, Wojciech, Jedrzejczak, Anna, Golab, Jakub, Dzwonek, Karolina, Dymek, Barbara, Sklepkiewicz, Piotr L, Zagozdzon, Agnieszka, Noonan, Tom, Mahboubi, Keyvan, Conway, Bruce, Sheeler, Ryan, Beckett, Paul, Hungerford, William M, Podjarny, Alberto, Mitschler, Andre, Cousido-Siah, Alexandra, Fadel, Firas, Golebiowski, Adam
Published in Journal of medicinal chemistry (08.02.2018)
Published in Journal of medicinal chemistry (08.02.2018)
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Journal Article
Discovery of selective, orally bioavailable inhibitor of mouse chitotriosidase
Mazur, Marzena, Bartoszewicz, Agnieszka, Dymek, Barbara, Salamon, Magdalena, Andryianau, Gleb, Kowalski, Michał, Olejniczak, Sylwia, Matyszewski, Krzysztof, Pluta, Elżbieta, Borek, Bartłomiej, Stefaniak, Filip, Zagozdzon, Agnieszka, Mazurkiewicz, Marcin, Koralewski, Robert, Czestkowski, Wojciech, Piotrowicz, Michał, Niedziejko, Piotr, Gruza, Mariusz M., Dzwonek, Karolina, Golebiowski, Adam, Golab, Jakub, Olczak, Jacek
Published in Bioorganic & medicinal chemistry letters (01.02.2018)
Published in Bioorganic & medicinal chemistry letters (01.02.2018)
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Journal Article
Design, Synthesis, and Development of pyrazolo[1,5-a]pyrimidine Derivatives as a Novel Series of Selective PI3Kδ Inhibitors: Part I—Indole Derivatives
Stypik, Mariola, Zagozda, Marcin, Michałek, Stanisław, Dymek, Barbara, Zdżalik-Bielecka, Daria, Dziachan, Maciej, Orłowska, Nina, Gunerka, Paweł, Turowski, Paweł, Hucz-Kalitowska, Joanna, Stańczak, Aleksandra, Stańczak, Paulina, Mulewski, Krzysztof, Smuga, Damian, Stefaniak, Filip, Gurba-Bryśkiewicz, Lidia, Leniak, Arkadiusz, Ochal, Zbigniew, Mach, Mateusz, Dzwonek, Karolina, Lamparska-Przybysz, Monika, Dubiel, Krzysztof, Wieczorek, Maciej
Published in Pharmaceuticals (Basel, Switzerland) (30.07.2022)
Published in Pharmaceuticals (Basel, Switzerland) (30.07.2022)
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Journal Article
The Role of Chitinases in Chronic Airway Inflammation Associated with Tobacco Smoke Exposure
Przysucha, Natalia, Górska, Katarzyna, Maskey-Warzęchowska, Marta, Proboszcz, Małgorzata, Nejman-Gryz, Patrycja, Paplińska-Goryca, Magdalena, Dymek, Barbara, Zagozdzon, Agnieszka, Krenke, Rafał
Published in Cells (Basel, Switzerland) (25.11.2022)
Published in Cells (Basel, Switzerland) (25.11.2022)
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Journal Article
Discovery of TRAF-2 and NCK-interacting kinase (TNIK) inhibitors by ligand-based virtual screening methods
Bujak, Anna, Stefaniak, Filip, Zdzalik, Daria, Grygielewicz, Paulina, Dymek, Barbara, Zagozda, Marcin, Gunerka, Pawel, Lamparska-Przybysz, Monika, Dubiel, Krzysztof, Wieczorek, Maciej, Dzwonek, Karolina
Published in MedChemComm (01.01.2015)
Published in MedChemComm (01.01.2015)
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Journal Article
Therapeutic efficacy of the chitotriosidase inhibitors in STAM model of non-alcoholic steatohepatitis
Mlacki, Michal, Dymek, Barbara, Zagozdzon, Agnieszka, Mazur, Marzena, Koralewski, Robert, Golebiewski, Adam, Dzwonek, Karolina, Dobrzanski, Pawel
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
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Journal Article
FRI105 - Therapeutic efficacy of the chitotriosidase inhibitors in STAM model of non-alcoholic steatohepatitis
Mlacki, Michal, Dymek, Barbara, Zagozdzon, Agnieszka, Mazur, Marzena, Koralewski, Robert, Golebiewski, Adam, Dzwonek, Karolina, Dobrzanski, Pawel
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
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Journal Article
Discovery and Pharmacokinetics of Sulfamides and Guanidines as Potent Human Arginase 1 Inhibitors
Blaszczyk, Roman, Brzezinska, Joanna, Dymek, Barbara, Stanczak, Paulina S, Mazurkiewicz, Marcin, Olczak, Jacek, Nowicka, Julita, Dzwonek, Karolina, Zagozdzon, Agnieszka, Golab, Jakub, Golebiowski, Adam
Published in ACS medicinal chemistry letters (09.04.2020)
Published in ACS medicinal chemistry letters (09.04.2020)
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Journal Article
Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis
Koralewski, Robert, Dymek, Barbara, Mazur, Marzena, Sklepkiewicz, Piotr, Olejniczak, Sylwia, Czestkowski, Wojciech, Matyszewski, Krzysztof, Andryianau, Gleb, Niedziejko, Piotr, Kowalski, Michal, Gruza, Mariusz, Borek, Bartłomiej, Jedrzejczak, Karol, Bartoszewicz, Agnieszka, Pluta, Elżbieta, Rymaszewska, Aleksandra, Kania, Magdalena, Rejczak, Tomasz, Piasecka, Sylwia, Mlacki, Michal, Mazurkiewicz, Marcin, Piotrowicz, Michał, Salamon, Magdalena, Zagozdzon, Agnieszka, Napiorkowska-Gromadzka, Agnieszka, Bartlomiejczak, Aneta, Mozga, Witold, Dobrzański, Paweł, Dzwonek, Karolina, Golab, Jakub, Nowotny, Marcin, Olczak, Jacek, Golebiowski, Adam
Published in Journal of medicinal chemistry (24.12.2020)
Published in Journal of medicinal chemistry (24.12.2020)
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Journal Article
Development of Dual Chitinase Inhibitors as Potential New Treatment for Respiratory System Diseases
Mazur, Marzena, Dymek, Barbara, Koralewski, Robert, Sklepkiewicz, Piotr, Olejniczak, Sylwia, Mazurkiewicz, Marcin, Piotrowicz, Michał, Salamon, Magdalena, Jędrzejczak, Karol, Zagozdzon, Agnieszka, Czestkowski, Wojciech, Matyszewski, Krzysztof, Borek, Bartłomiej, Bartoszewicz, Agnieszka, Pluta, Elżbieta, Rymaszewska, Aleksandra, Mozga, Witold, Stefaniak, Filip, Dobrzański, Paweł, Dzwonek, Karolina, Golab, Jakub, Golebiowski, Adam, Olczak, Jacek
Published in Journal of medicinal chemistry (08.08.2019)
Published in Journal of medicinal chemistry (08.08.2019)
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Journal Article
Activating mutations in ALK kinase domain confer resistance to structurally unrelated ALK inhibitors in NPM-ALK-positive anaplastic large-cell lymphoma
Zdzalik, Daria, Dymek, Barbara, Grygielewicz, Paulina, Gunerka, Pawel, Bujak, Anna, Lamparska-Przybysz, Monika, Wieczorek, Maciej, Dzwonek, Karolina
Published in Journal of cancer research and clinical oncology (01.04.2014)
Published in Journal of cancer research and clinical oncology (01.04.2014)
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Journal Article
Differences in gene expression and alterations in cell cycle of acute myeloid leukemia cell lines after treatment with JAK inhibitors
Gunerka, Pawel, Dymek, Barbara, Stanczak, Aleksandra, Bujak, Anna, Grygielewicz, Paulina, Turowski, Pawel, Dzwonek, Karolina, Lamparska-Przybysz, Monika, Pietrucha, Tadeusz, Wieczorek, Maciej
Published in European journal of pharmacology (15.10.2015)
Published in European journal of pharmacology (15.10.2015)
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Journal Article
Design, Synthesis, and Development of pyrazolo[1,5-Ia/I]pyrimidine Derivatives as a Novel Series of Selective PI3KIδ/I Inhibitors: Part I—Indole Derivatives
Stypik, Mariola, Zagozda, Marcin, Michałek, Stanisław, Dymek, Barbara, Zdżalik-Bielecka, Daria, Dziachan, Maciej, Orłowska, Nina, Gunerka, Paweł, Turowski, Paweł, Hucz-Kalitowska, Joanna, Stańczak, Aleksandra, Stańczak, Paulina, Mulewski, Krzysztof, Smuga, Damian, Stefaniak, Filip, Gurba-Bryśkiewicz, Lidia, Leniak, Arkadiusz, Ochal, Zbigniew, Mach, Mateusz, Dzwonek, Karolina, Lamparska-Przybysz, Monika, Dubiel, Krzysztof, Wieczorek, Maciej
Published in Pharmaceuticals (Basel, Switzerland) (01.07.2022)
Published in Pharmaceuticals (Basel, Switzerland) (01.07.2022)
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Journal Article
Benzoxazepine-Derived Selective, Orally Bioavailable Inhibitor of Human Acidic Mammalian Chitinase
Andryianau, Gleb, Kowalski, Michal, Piotrowicz, Michal C., Rajkiewicz, Adam A., Dymek, Barbara, Sklepkiewicz, Piotr L., Pluta, Elzbieta, Stefaniak, Filip, Czestkowski, Wojciech, Olejniczak, Sylwia, Mazur, Marzena, Niedziejko, Piotr, Koralewski, Robert, Matyszewski, Krzysztof, Gruza, Mariusz, Zagozdzon, Agnieszka, Salamon, Magdalena, Rymaszewska, Aleksandra, Welzer, Mikolaj, Dzwonek, Karolina, Golab, Jakub, Olczak, Jacek, Bartoszewicz, Agnieszka, Golebiowski, Adam
Published in ACS medicinal chemistry letters (11.06.2020)
Published in ACS medicinal chemistry letters (11.06.2020)
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Journal Article
Pharmacological Inhibition of Chitotriosidase
Guner, Nazan Cemre, Gorska, Katarzyna, Thusen, Jan H. von der, Mlacki, Michal, Zaslona, Zbigniew, Proboszcz, Malgorzata, Krzeminski, Lukasz, Paplinska-Goryca, Magdalena, Zagozdzon, Agnieszka, Nejman-Gryz, Patrycja, Przysucha, Natalia, Drzewicka, Katarzyna, Sklepkiewicz, Piotr, Dymek, Barbara, Dzwonek, Karolina, Rymaszewska, Aleksandra, Dobrzanski, Pawel, Krenke, Rafal
Published in Journal of inflammation research (31.10.2022)
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Published in Journal of inflammation research (31.10.2022)
Journal Article
Pharmacological Inhibition of Chitotriosidase (CHIT1) as a Novel Therapeutic Approach for Sarcoidosis
Dymek, Barbara, Sklepkiewicz, Piotr, Mlacki, Michal, Guner, Nazan Cemre, Nejman-Gryz, Patrycja, Drzewicka, Katarzyna, Przysucha, Natalia, Rymaszewska, Aleksandra, Paplinska-Goryca, Magdalena, Zagozdzon, Agnieszka, Proboszcz, Malgorzata, Krzeminski, Lukasz, Thusen, Jan H. von der, Gorska, Katarzyna, Dzwonek, Karolina, Zaslona, Zbigniew, Dobrzanski, Pawel, Krenke, Rafal
Published in Journal of inflammation research (01.01.2022)
Published in Journal of inflammation research (01.01.2022)
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Journal Article