SB-649915-B, a novel 5-HT1A/B autoreceptor antagonist and serotonin reuptake inhibitor, is anxiolytic and displays fast onset activity in the rat high light social interaction test
Starr, Kathryn R, Price, Gary W, Watson, Jeannette M, Atkinson, Peter J, Arban, Roberto, Melotto, Sergio, Dawson, Lee A, Hagan, Jim J, Upton, Neil, Duxon, Mark S
Published in Neuropsychopharmacology (New York, N.Y.) (01.10.2007)
Published in Neuropsychopharmacology (New York, N.Y.) (01.10.2007)
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LABORAS™: Initial pharmacological validation of a system allowing continuous monitoring of laboratory rodent behaviour
Quinn, Leann P, Stean, Tania O, Trail, Brenda, Duxon, Mark S, Stratton, Sharon C, Billinton, Andrew, Upton, Neil
Published in Journal of neuroscience methods (30.11.2003)
Published in Journal of neuroscience methods (30.11.2003)
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Repeated sensory contact with aggressive mice rapidly leads to an anticipatory increase in core body temperature and physical activity that precedes the onset of aversive responding
Pardon, Marie-Christine, Kendall, David A., Pérez-Diaz, Fernando, Duxon, Mark S., Marsden, Charles A.
Published in The European journal of neuroscience (01.08.2004)
Published in The European journal of neuroscience (01.08.2004)
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3,4-Dihydro-2H-benzoxazinones are 5-HT1A receptor antagonists with potent 5-HT reuptake inhibitory activity
ATKINSON, Peter J, BROMIDGE, Steven M, RAMI, Harshad K, RILEY, Graham J, SCOTT, Claire M, SHAW, Tracey E, STARR, Kathryn R, STEMP, Geoffrey, THEWLIS, Kevin M, THOMAS, David R, THOMPSON, Mervyn, VONG, Antonio K. K, DUXON, Mark S, WATSON, Jeannette M, GASTER, Laramie M, HADLEY, Michael S, HAMMOND, Beverley, JOHNSON, Christopher N, MIDDLEMISS, Derek N, NORTH, Stephanie E, PRICE, Gary W
Published in Bioorganic & medicinal chemistry letters (01.02.2005)
Published in Bioorganic & medicinal chemistry letters (01.02.2005)
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A novel behavioural registration system LABORAS™ and the social interaction paradigm detect long-term functional deficits following middle cerebral artery occlusion in the rat
Quinn, Leann P., Grundy, Robert I., Campbell, Colin A., Collier, Sarah, Lawman, Amanda, Stean, Tania O., Billinton, Andrew, Parsons, Andrew A., Upton, Neil, Duxon, Mark S., Irving, Elaine A.
Published in Brain research (07.01.2005)
Published in Brain research (07.01.2005)
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Immunohistochemical localisation of the 5-HT2C receptor protein in the rat CNS
CLEMETT, D. A, PUNHANI, T, DUXON, M. S, BLACKBURN, T. P, FONE, K. C. F
Published in Neuropharmacology (2000)
Published in Neuropharmacology (2000)
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The development of an Irwin-like test in the nonhuman primate for CNS safety assessment
Froget, Guillaume, Cruz, Christopher, Hubert, Isabelle, Virley, David, Lemaire, Martine, Duxon, Mark S., Porsolt, Roger D.
Published in Journal of pharmacological and toxicological methods (01.09.2012)
Published in Journal of pharmacological and toxicological methods (01.09.2012)
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Evidence that orexin-A-evoked grooming in the rat is mediated by orexin-1 (OX1) receptors, with downstream 5-HT2C receptor involvement
DUXON, Mark S, STRETTON, Jennifer, WAI CHAN, PORTER, Rod A, UPTON, Neil, STARR, Kathryn, JONES, Declan N. C, HOLLAND, Vicky, RILEY, Graham, JERMAN, Jeff, BROUGH, Stephen, SMART, Darren, JOHNS, Amanda
Published in Psychopharmacologia (01.01.2001)
Published in Psychopharmacologia (01.01.2001)
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SB-649915-B, a novel s-HTIA/B autoreceptor antagonist and serotonin reuptake inhibitor, is anxiolytic and displays fast onset activity in the rat high light social interaction test
STARR, Kathryn R, PRICE, Gary W, WATSON, Jeannette M, ATKINSON, Peter J, ARBAN, Roberto, MELOTTO, Sergio, DAWSON, Lee A, HAGAN, Jim J, UPTON, Neil, DUXON, Mark S
Published in Neuropsychopharmacology (New York, N.Y.) (2007)
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Published in Neuropsychopharmacology (New York, N.Y.) (2007)
Journal Article
3,4-Dihydro-2H-benzoxazinones are 5-HT(1A) receptor antagonists with potent 5-HT reuptake inhibitory activity
Atkinson, Peter J, Bromidge, Steven M, Duxon, Mark S, Gaster, Laramie M, Hadley, Michael S, Hammond, Beverley, Johnson, Christopher N, Middlemiss, Derek N, North, Stephanie E, Price, Gary W, Rami, Harshad K, Riley, Graham J, Scott, Claire M, Shaw, Tracey E, Starr, Kathryn R, Stemp, Geoffrey, Thewlis, Kevin M, Thomas, David R, Thompson, Mervyn, Vong, Antonio K K, Watson, Jeannette M
Published in Bioorganic & medicinal chemistry letters (01.02.2005)
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Published in Bioorganic & medicinal chemistry letters (01.02.2005)
Journal Article
3,4-Dihydro-2 H-benzoxazinones are 5-HT 1A receptor antagonists with potent 5-HT reuptake inhibitory activity
Atkinson, Peter J., Bromidge, Steven M., Duxon, Mark S., Gaster, Laramie M., Hadley, Michael S., Hammond, Beverley, Johnson, Christopher N., Middlemiss, Derek N., North, Stephanie E., Price, Gary W., Rami, Harshad K., Riley, Graham J., Scott, Claire M., Shaw, Tracey E., Starr, Kathryn R., Stemp, Geoffrey, Thewlis, Kevin M., Thomas, David R., Thompson, Mervyn, Vong, Antonio K.K., Watson, Jeannette M.
Published in Bioorganic & medicinal chemistry letters (2005)
Published in Bioorganic & medicinal chemistry letters (2005)
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Journal Article
Evidence that orexin-A-evoked grooming in the rat is mediated by orexin-1 (OX 1 ) receptors, with downstream 5-HT 2C receptor involvement
Duxon, Mark S., Stretton, Jennifer, Starr, Kathryn, Jones, Declan N.C., Holland, Vicky, Riley, Graham, Jerman, Jeff, Brough, Stephen, Smart, Darren, Johns, Amanda, Chan, Wai, Porter, Rod A., Upton, Neil
Published in Psychopharmacology (09.01.2001)
Published in Psychopharmacology (09.01.2001)
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