Balancing Cationic and Hydrophobic Content of PEGylated siRNA Polyplexes Enhances Endosome Escape, Stability, Blood Circulation Time, and Bioactivity in Vivo
Nelson, Christopher E, Kintzing, James R, Hanna, Ann, Shannon, Joshua M, Gupta, Mukesh K, Duvall, Craig L
Published in ACS nano (22.10.2013)
Published in ACS nano (22.10.2013)
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Lipophilic siRNA targets albumin in situ and promotes bioavailability, tumor penetration, and carrier-free gene silencing
Sarett, Samantha M., Werfel, Thomas A., Lee, Linus, Jackson, Meredith A., Kilchrist, Kameron V., Brantley-Sieders, Dana, Duvall, Craig L.
Published in Proceedings of the National Academy of Sciences - PNAS (08.08.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (08.08.2017)
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Technologies for controlled, local delivery of siRNA
Sarett, Samantha M., Nelson, Christopher E., Duvall, Craig L.
Published in Journal of controlled release (28.11.2015)
Published in Journal of controlled release (28.11.2015)
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Zwitterionic Nanocarrier Surface Chemistry Improves siRNA Tumor Delivery and Silencing Activity Relative to Polyethylene Glycol
Jackson, Meredith A, Werfel, Thomas A, Curvino, Elizabeth J, Yu, Fang, Kavanaugh, Taylor E, Sarett, Samantha M, Dockery, Mary D, Kilchrist, Kameron V, Jackson, Ayisha N, Giorgio, Todd D, Duvall, Craig L
Published in ACS nano (27.06.2017)
Published in ACS nano (27.06.2017)
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Ex vivo red blood cell hemolysis assay for the evaluation of pH-responsive endosomolytic agents for cytosolic delivery of biomacromolecular drugs
Evans, Brian C, Nelson, Christopher E, Yu, Shann S, Beavers, Kelsey R, Kim, Arnold J, Li, Hongmei, Nelson, Heather M, Giorgio, Todd D, Duvall, Craig L
Published in Journal of visualized experiments (09.03.2013)
Published in Journal of visualized experiments (09.03.2013)
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Journal Article
Tuning PEGylation of mixed micelles to overcome intracellular and systemic siRNA delivery barriers
Miteva, Martina, Kirkbride, Kellye C, Kilchrist, Kameron V, Werfel, Thomas A, Li, Hongmei, Nelson, Christopher E, Gupta, Mukesh K, Giorgio, Todd D, Duvall, Craig L
Published in Biomaterials (01.01.2015)
Published in Biomaterials (01.01.2015)
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An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles
Evans, Brian C., Fletcher, R. Brock, Kilchrist, Kameron V., Dailing, Eric A., Mukalel, Alvin J., Colazo, Juan M., Oliver, Matthew, Cheung-Flynn, Joyce, Brophy, Colleen M., Tierney, John W., Isenberg, Jeffrey S., Hankenson, Kurt D., Ghimire, Kedar, Lander, Cynthia, Gersbach, Charles A., Duvall, Craig L.
Published in Nature communications (01.11.2019)
Published in Nature communications (01.11.2019)
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Matrix Metalloproteinase Responsive, Proximity-Activated Polymeric Nanoparticles for siRNA Delivery
Li, Hongmei, Yu, Shann S., Miteva, Martina, Nelson, Christopher E., Werfel, Thomas, Giorgio, Todd D., Duvall, Craig L.
Published in Advanced functional materials (25.06.2013)
Published in Advanced functional materials (25.06.2013)
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Selective mTORC2 Inhibitor Therapeutically Blocks Breast Cancer Cell Growth and Survival
Werfel, Thomas A, Wang, Shan, Jackson, Meredith A, Kavanaugh, Taylor E, Joly, Meghan Morrison, Lee, Linus H, Hicks, Donna J, Sanchez, Violeta, Ericsson, Paula Gonzalez, Kilchrist, Kameron V, Dimobi, Somtochukwu C, Sarett, Samantha M, Brantley-Sieders, Dana M, Cook, Rebecca S, Duvall, Craig L
Published in Cancer research (Chicago, Ill.) (01.04.2018)
Published in Cancer research (Chicago, Ill.) (01.04.2018)
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Tuning Composition of Polymer and Porous Silicon Composite Nanoparticles for Early Endosome Escape of Anti-microRNA Peptide Nucleic Acids
Kelly, Isom B, Fletcher, R. Brock, McBride, James R, Weiss, Sharon M, Duvall, Craig L
Published in ACS applied materials & interfaces (02.09.2020)
Published in ACS applied materials & interfaces (02.09.2020)
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Macrophage-Specific RNA Interference Targeting via “Click”, Mannosylated Polymeric Micelles
Yu, Shann S, Lau, Cheryl M, Barham, Whitney J, Onishko, Halina M, Nelson, Christopher E, Li, Hongmei, Smith, Chelsey A, Yull, Fiona E, Duvall, Craig L, Giorgio, Todd D
Published in Molecular pharmaceutics (04.03.2013)
Published in Molecular pharmaceutics (04.03.2013)
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Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice
Shen, Xing, Wan, Chao, Ramaswamy, Girish, Mavalli, Mahendra, Wang, Ying, Duvall, Craig L., Deng, Lian Fu, Guldberg, Robert E., Eberhart, Alan, Clemens, Thomas L., Gilbert, Shawn R.
Published in Journal of orthopaedic research (01.10.2009)
Published in Journal of orthopaedic research (01.10.2009)
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Fibrinolysis is essential for fracture repair and prevention of heterotopic ossification
Yuasa, Masato, Mignemi, Nicholas A, Nyman, Jeffry S, Duvall, Craig L, Schwartz, Herbert S, Okawa, Atsushi, Yoshii, Toshitaka, Bhattacharjee, Gourab, Zhao, Chenguang, Bible, Jesse E, Obremskey, William T, Flick, Matthew J, Degen, Jay L, Barnett, Joey V, Cates, Justin M M, Schoenecker, Jonathan G
Published in The Journal of clinical investigation (03.08.2015)
Published in The Journal of clinical investigation (03.08.2015)
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Sustained VEGF delivery via PLGA nanoparticles promotes vascular growth
Golub, Justin S, Kim, Young-tae, Duvall, Craig L, Bellamkonda, Ravi V, Gupta, Divya, Lin, Angela S, Weiss, Daiana, Robert Taylor, W, Guldberg, Robert E
Published in American journal of physiology. Heart and circulatory physiology (01.06.2010)
Published in American journal of physiology. Heart and circulatory physiology (01.06.2010)
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Journal Article
Dual MMP7-Proximity-Activated and Folate Receptor-Targeted Nanoparticles for siRNA Delivery
Li, Hongmei, Miteva, Martina, Kirkbride, Kellye C, Cheng, Ming J, Nelson, Christopher E, Simpson, Elaine M, Gupta, Mukesh K, Duvall, Craig L, Giorgio, Todd D
Published in Biomacromolecules (12.01.2015)
Published in Biomacromolecules (12.01.2015)
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Structural optimization of siRNA conjugates for albumin binding achieves effective MCL1-directed cancer therapy
Hoogenboezem, Ella N., Patel, Shrusti S., Lo, Justin H., Cavnar, Ashley B., Babb, Lauren M., Francini, Nora, Gbur, Eva F., Patil, Prarthana, Colazo, Juan M., Michell, Danielle L., Sanchez, Violeta M., McCune, Joshua T., Ma, Jinqi, DeJulius, Carlisle R., Lee, Linus H., Rosch, Jonah C., Allen, Ryan M., Stokes, Larry D., Hill, Jordan L., Vickers, Kasey C., Cook, Rebecca S., Duvall, Craig L.
Published in Nature communications (21.02.2024)
Published in Nature communications (21.02.2024)
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