Metformin antinociceptive effect in models of nociceptive and neuropathic pain is partially mediated by activation of opioidergic mechanisms
Augusto, Paulo S.A., Braga, Alysson V., Rodrigues, Felipe F., Morais, Marcela I., Dutra, Marcela M.G.B., Batista, Carla R.A., Melo, Ivo S.F., Costa, Sarah O.A.M., Goulart, Franciele A., Coelho, Márcio M., Machado, Renes R.
Published in European journal of pharmacology (05.09.2019)
Published in European journal of pharmacology (05.09.2019)
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Role of peripheral 5-HT1D, 5-HT3 and 5-HT7 receptors in the mechanical allodynia induced by serotonin in mice
Nascimento, Elias B., Romero, Thiago R.L., Dutra, Marcela M.G.B., Fiebich, Bernd L., Duarte, Igor D.G., Coelho, Márcio M.
Published in Biomedicine & pharmacotherapy (01.03.2021)
Published in Biomedicine & pharmacotherapy (01.03.2021)
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Nicorandil inhibits mechanical allodynia induced by paclitaxel by activating opioidergic and serotonergic mechanisms
Morais, Marcela I., Rodrigues, Felipe F., Costa, Sarah O.A.M., Goulart, Franciele A., Costa, Fábio C., Melo, Ivo S.F., Augusto, Paulo S.A., Dutra, Marcela M.G.B., de Fátima, Ângelo, Coelho, Márcio M., Machado, Renes R.
Published in European journal of pharmacology (05.04.2018)
Published in European journal of pharmacology (05.04.2018)
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Metformin effect in models of inflammation is associated with activation of ATP-dependent potassium channels and inhibition of tumor necrosis factor-α production
Augusto, Paulo S. A., Matsui, Tamires C., Braga, Alysson V., Rodrigues, Felipe F., Morais, Marcela I., Dutra, Marcela M. G. B., Batista, Carla R. A., Melo, Ivo S. F., Costa, Sarah O. A. M., Bertollo, Caryne M., Coelho, Márcio M., Machado, Renes R.
Published in Inflammopharmacology (01.02.2022)
Published in Inflammopharmacology (01.02.2022)
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The phthalimide analogues N-3-hydroxypropylphthalimide and N-carboxymethyl-3-nitrophthalimide exhibit activity in experimental models of inflammatory and neuropathic pain
Batista, Carla R.A., Godin, Adriana M., Melo, Ivo S.F., Coura, Giovanna M.E., Matsui, Tamires C., Dutra, Marcela M.G.B., Brito, Ana Mercy S., Canhestro, Wagner G., Alves, Ricardo J., Araújo, Débora P., de Fátima, Ângelo, Machado, Renes R., Coelho, Márcio M.
Published in Pharmacological reports (01.12.2019)
Published in Pharmacological reports (01.12.2019)
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Clindamycin inhibits nociceptive response by reducing tumor necrosis factor-α and CXCL-1 production and activating opioidergic mechanisms
Rodrigues, Felipe F., Morais, Marcela I., Melo, Ivo S. F., Augusto, Paulo S. A., Dutra, Marcela M. G. B., Costa, Sarah O. A. M., Costa, Fábio C., Goulart, Franciele A., Braga, Alysson V., Coelho, Márcio M., Machado, Renes R.
Published in Inflammopharmacology (01.04.2020)
Published in Inflammopharmacology (01.04.2020)
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Opioid pathways activation mediates the activity of nicorandil in experimental models of nociceptive and inflammatory pain
Dutra, Marcela M.G.B., Nascimento, Elias B., Godin, Adriana M., Brito, Ana Mercy S., Melo, Ivo S.F., Augusto, Paulo S.A., Rodrigues, Felipe F., Araújo, Débora P., de Fátima, Ângelo, Coelho, Márcio M., Machado, Renes R.
Published in European journal of pharmacology (05.12.2015)
Published in European journal of pharmacology (05.12.2015)
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Antivirals for adult patients hospitalised with SARS-CoV-2 infection: a randomised, phase II/III, multicentre, placebo-controlled, adaptive study, with multiple arms and stages. COALITION COVID-19 BRAZIL IX – REVOLUTIOn trial
Maia, Israel S., Marcadenti, Aline, Veiga, Viviane C., Miranda, Tamiris A., Gomes, Samara P.C., Carollo, Mariana B.S., Negrelli, Karina L., Gomes, Jackeline O., Tramujas, Lucas, Abreu-Silva, Erlon O., Westphal, Glauco A., Fernandes, Ruthy P., Horta, Jacques G.A., Oliveira, Deborah C., Flato, Uri A.P., Paoliello, Ricardo C.R., Fernandes, Camilo, Zandonai, Cássio L., Coelho, Juliana C., Barros, Waldemar C., Lemos, Juliana C., Bolan, Renata S., Dutra, Marcela M., Gebara, Otavio C.E., Lopes, Ana T.A., Alencar Filho, Meton S., Arraes, Jussara A., Hamamoto, Victor A., Hernandes, Mauro E., Golin, Nicole A., Santos, Tiago M., Santos, Renato H.N., Damiani, Lucas P., Zampieri, Fernando G., Gesto, João, Machado, Flávia R., Rosa, Régis G., Azevedo, Luciano C.P., Avezum, Alvaro, Lopes, Renato D., Souza, Thiago M.L., Berwanger, Otávio, Cavalcanti, Alexandre B.
Published in Lancet Regional Health - Americas (Online) (01.04.2023)
Published in Lancet Regional Health - Americas (Online) (01.04.2023)
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Sex-independent suppression of experimental inflammatory pain by minocycline in two mouse strains
Bastos, Leandro F.S., Prazeres, Júlia D.M., Godin, Adriana M., Menezes, Raquel R., Soares, Darly G., Ferreira, Wallace C., Dutra, Marcela M.G.B., Machado, Renes R., Coelho, Márcio M.
Published in Neuroscience letters (11.10.2013)
Published in Neuroscience letters (11.10.2013)
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Journal Article
Synthesis, antinociceptive activity and pharmacokinetic profiles of nicorandil and its isomers
César, Isabela C., Godin, Adriana M., Araujo, Débora P., Oliveira, Francinely C., Menezes, Raquel R., Santos, Julliana R.A., Almeida, Mariana O., Dutra, Marcela M.G.B., Santos, Daniel A., Machado, Renes R., Pianetti, Gerson A., Coelho, Márcio M., de Fátima, Ângelo
Published in Bioorganic & medicinal chemistry (01.05.2014)
Published in Bioorganic & medicinal chemistry (01.05.2014)
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Journal Article
Activity of nicorandil, a nicotinamide derivative with a nitrate group, in the experimental model of pain induced by formaldehyde in mice
Dutra, Marcela M.G.B., Godin, Adriana M., César, Isabela C., Nascimento, Elias B., Menezes, Raquel R., Ferreira, Wallace C., Soares, Darly G., Seniuk, João Gabriel T., Araújo, Débora P., Bastos, Leandro F.S., Pianetti, Gerson A., Fátima, Ângelo de, Machado, Renes R., Coelho, Márcio M.
Published in Pharmacology, biochemistry and behavior (01.05.2013)
Published in Pharmacology, biochemistry and behavior (01.05.2013)
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Journal Article
Antiallodynic activity of leflunomide is partially inhibited by naltrexone and glibenclamide and associated with reduced production of TNF-α and CXCL-1
Brito, Ana Mercy S., Godin, Adriana M., Augusto, Paulo Sérgio A., Menezes, Raquel R., Melo, Ivo S.F., Dutra, Marcela G.M.B., Costa, Sarah O.A.M., Goulart, Franciele A., Rodrigues, Felipe F., Ísis Morais, Marcela, Machado, Renes R., Coelho, Márcio M.
Published in European journal of pharmacology (05.01.2018)
Published in European journal of pharmacology (05.01.2018)
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Journal Article
The phthalimide analogues N-3-hydroxypropylphthalimide and N-carboxymethyl-3-nitrophthalimide exhibit activity in experimental models of inflammatory and neuropathic pain
Batista, Carla R A, Godin, Adriana M, Melo, Ivo S F, Coura, Giovanna M E, Matsui, Tamires C, Dutra, Marcela M G B, Brito, Ana Mercy S, Canhestro, Wagner G, Alves, Ricardo J, Araújo, Débora P, de Fátima, Ângelo, Machado, Renes R, Coelho, Márcio M
Published in Pharmacological reports (01.11.2019)
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Published in Pharmacological reports (01.11.2019)
Journal Article
Role of peripheral 5-HT 1D , 5-HT 3 and 5-HT 7 receptors in the mechanical allodynia induced by serotonin in mice
Nascimento, Jr, Elias B, Romero, Thiago R L, Dutra, Marcela M G B, Fiebich, Bernd L, Duarte, Igor D G, Coelho, Márcio M
Published in Biomedicine & pharmacotherapy (01.03.2021)
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Published in Biomedicine & pharmacotherapy (01.03.2021)
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Antivirals for adult patients hospitalised with SARS-CoV-2 infection: a randomised, phase II/III, multicentre, placebo-controlled, adaptive study, with multiple arms and stages. COALITION COVID-19 BRAZIL IX – REVOLUTIOn trialResearch in context
Israel S. Maia, Aline Marcadenti, Viviane C. Veiga, Tamiris A. Miranda, Samara P.C. Gomes, Mariana B.S. Carollo, Karina L. Negrelli, Jackeline O. Gomes, Lucas Tramujas, Erlon O. Abreu-Silva, Glauco A. Westphal, Ruthy P. Fernandes, Jacques G.A. Horta, Deborah C. Oliveira, Uri A.P. Flato, Ricardo C.R. Paoliello, Camilo Fernandes, Cássio L. Zandonai, Juliana C. Coelho, Waldemar C. Barros, Juliana C. Lemos, Renata S. Bolan, Marcela M. Dutra, Otavio C.E. Gebara, Ana T.A. Lopes, Meton S. Alencar Filho, Jussara A. Arraes, Victor A. Hamamoto, Mauro E. Hernandes, Nicole A. Golin, Tiago M. Santos, Renato H.N. Santos, Lucas P. Damiani, Fernando G. Zampieri, João Gesto, Flávia R. Machado, Régis G. Rosa, Luciano C.P. Azevedo, Alvaro Avezum, Renato D. Lopes, Thiago M.L. Souza, Otávio Berwanger, Alexandre B. Cavalcanti
Published in Lancet Regional Health - Americas (Online) (01.04.2023)
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Published in Lancet Regional Health - Americas (Online) (01.04.2023)
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