Optimization of 4-Phenylamino-3-quinolinecarbonitriles as Potent Inhibitors of Src Kinase Activity
Boschelli, Diane H, Ye, Fei, Wang, Yanong D, Dutia, Minu, Johnson, Steve L, Wu, Biqi, Miller, Karen, Powell, Dennis W, Yaczko, Deanna, Young, Mairead, Tischler, Mark, Arndt, Kim, Discafani, Carolyn, Etienne, Carlo, Gibbons, Jay, Grod, Janet, Lucas, Judy, Weber, Jennifer M, Boschelli, Frank
Published in Journal of medicinal chemistry (08.11.2001)
Published in Journal of medicinal chemistry (08.11.2001)
Get full text
Journal Article
Synthesis and Src Kinase Inhibitory Activity of a Series of 4-Phenylamino-3-quinolinecarbonitriles
Boschelli, Diane H, Wang, Yanong D, Ye, Fei, Wu, Biqi, Zhang, Nan, Dutia, Minu, Powell, Dennis W, Wissner, Allan, Arndt, Kim, Weber, Jennifer M, Boschelli, Frank
Published in Journal of medicinal chemistry (01.03.2001)
Published in Journal of medicinal chemistry (01.03.2001)
Get full text
Journal Article
Indazolylpyrazolopyrimidine as Highly Potent B-Raf Inhibitors with in Vivo Activity
Wang, Xiaolun, Berger, Dan M, Salaski, Edward J, Torres, Nancy, Dutia, Minu, Hanna, Cilien, Hu, Yongbo, Levin, Jeremy I, Powell, Dennis, Wojciechowicz, Donald, Collins, Karen, Frommer, Eileen, Lucas, Judy
Published in Journal of medicinal chemistry (11.11.2010)
Published in Journal of medicinal chemistry (11.11.2010)
Get full text
Journal Article
Lead identification to generate 3-cyanoquinoline inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment
Miller, Lori M., Mayer, Scott C., Berger, Dan M., Boschelli, Diane H., Boschelli, Frank, Di, Li, Du, Xuemei, Dutia, Minu, Floyd, Middleton B., Johnson, Mark, Kenny, Cynthia Hess, Krishnamurthy, Girija, Moy, Franklin, Petusky, Susan, Tkach, Diane, Torres, Nancy, Wu, Biqi, Xu, Weixin
Published in Bioorganic & medicinal chemistry letters (2009)
Published in Bioorganic & medicinal chemistry letters (2009)
Get full text
Journal Article
Disodium (R,R)-5-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate (CL 316,243). A potent .beta.-adrenergic agonist virtually specific for .beta.3 receptors. A promising antidiabetic and antiobesity agent
Bloom, Jonathan D, Dutia, Minu D, Johnson, Bernard D, Wissner, Allan, Burns, Michael G, Largis, Elwood E, Dolan, Jo Alene, Claus, Thomas H
Published in Journal of medicinal chemistry (01.08.1992)
Published in Journal of medicinal chemistry (01.08.1992)
Get full text
Journal Article
Potential antiatherosclerotic agents. 6. Hypocholesterolemic trisubstituted urea analogs
DeVries, Vern G, Bloom, Jonathan D, Dutia, Minu D, Katocs, Andrew S, Largis, Elwood E
Published in Journal of medicinal chemistry (01.10.1989)
Published in Journal of medicinal chemistry (01.10.1989)
Get full text
Journal Article
Non-hinge-binding pyrazolo[1,5- a]pyrimidines as potent B-Raf kinase inhibitors
Berger, Dan M., Torres, Nancy, Dutia, Minu, Powell, Dennis, Ciszewski, Greg, Gopalsamy, Ariamala, Levin, Jeremy I., Kim, Kyung-Hee, Xu, Weixin, Wilhelm, James, Hu, YongBo, Collins, Karen, Feldberg, Larry, Kim, Steven, Frommer, Eileen, Wojciechowicz, Donald, Mallon, Robert
Published in Bioorganic & medicinal chemistry letters (01.12.2009)
Published in Bioorganic & medicinal chemistry letters (01.12.2009)
Get full text
Journal Article
Novel pyrazolopyrimidines as highly potent B-Raf inhibitors
Di Grandi, Martin J., Berger, Dan M., Hopper, Darrin W., Zhang, Chunchun, Dutia, Minu, Dunnick, Alejandro L., Torres, Nancy, Levin, Jeremy I., Diamantidis, George, Zapf, Christoph W., Bloom, Jonathan D., Hu, YongBo, Powell, Dennis, Wojciechowicz, Donald, Collins, Karen, Frommer, Eileen
Published in Bioorganic & medicinal chemistry letters (15.12.2009)
Published in Bioorganic & medicinal chemistry letters (15.12.2009)
Get full text
Journal Article
Observation of differential reactivity of cyclic amines in SN2 and SNAr displacement reactions in the course of synthesizing C-6, C-7 substituted quinolinecarbonitrile MEK1 kinase inhibitors
Hopper, Darrin W., Dutia, Minu, Berger, Dan M., Powell, Dennis W.
Published in Tetrahedron letters (01.01.2008)
Published in Tetrahedron letters (01.01.2008)
Get full text
Journal Article
Observation of differential reactivity of cyclic amines in S(N)2 and SNAr displacement reactions in the course of synthesizing C-6, C-7 substituted quinolinecarbonitrile MEK1 kinase inhibitors
Hopper, Darrin W., Dutia, Minu, Berger, Dan M., Powell, Dennis W.
Published in Tetrahedron letters (01.01.2008)
Published in Tetrahedron letters (01.01.2008)
Get full text
Journal Article
4-Anilino-7-alkenylquinoline-3-carbonitriles as potent MEK1 kinase inhibitors
Berger, Dan M., Dutia, Minu, Powell, Dennis, Floyd, Middleton B., Torres, Nancy, Mallon, Robert, Wojciechowicz, Donald, Kim, Steven, Feldberg, Larry, Collins, Karen, Chaudhary, Inder
Published in Bioorganic & medicinal chemistry (15.10.2008)
Published in Bioorganic & medicinal chemistry (15.10.2008)
Get full text
Journal Article
Observation of differential reactivity of cyclic amines in S N2 and S NAr displacement reactions in the course of synthesizing C-6, C-7 substituted quinolinecarbonitrile MEK1 kinase inhibitors
Hopper, Darrin W., Dutia, Minu, Berger, Dan M., Powell, Dennis W.
Published in Tetrahedron letters (2008)
Published in Tetrahedron letters (2008)
Get full text
Journal Article
Novel Multidrug Resistance Reversal Agents
Berger, Dan, Citarella, Ron, Dutia, Minu, Greenberger, Lee, Hallett, William, Paul, Rolf, Powell, Dennis
Published in Journal of medicinal chemistry (17.06.1999)
Published in Journal of medicinal chemistry (17.06.1999)
Get full text
Journal Article
4-Anilino-7-alkenylquinoIine-3-carbonitriles as potent MEI1 kinase inhibitors
BERGER, Dan M, DUTIA, Minu, CHAUDHARY, Inder, POWELL, Dennis, FLOYD, Middleton B, TORRES, Nancy, MALLON, Robert, WOJCIECHOWICZ, Donald, KIM, Steven, FELDBERG, Larry, COLLINS, Karen
Published in Bioorganic & medicinal chemistry (2008)
Get full text
Published in Bioorganic & medicinal chemistry (2008)
Journal Article
4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonitriles as Potent Src Kinase Inhibitors
Berger, Dan M, Dutia, Minu, Birnberg, Gary, Powell, Dennis, Boschelli, Diane H, Wang, Yanong D, Ravi, Malini, Yaczko, Deanna, Golas, Jennifer, Lucas, Judy, Boschelli, Frank
Published in Journal of medicinal chemistry (22.09.2005)
Published in Journal of medicinal chemistry (22.09.2005)
Get full text
Journal Article
Potential antiatherosclerotic agents. 5. An acyl-coenzyme A:cholesterol O-acyltransferase inhibitor with hypocholesterolemic activity
DeVries, Vern G, Schaffer, Sheldon A, Largis, Elwood E, Dutia, Minu D, Wang, Ching Hua, Bloom, Jonathan D, Katocs, Andrew S
Published in Journal of medicinal chemistry (01.07.1986)
Published in Journal of medicinal chemistry (01.07.1986)
Get full text
Journal Article
Substituted 4-anilino-7-phenyl-3-quinolinecarbonitriles as Src kinase inhibitors
BERGER, Dan, DUTIA, Minu, POWELL, Dennis, WISSNER, Allan, DEMORIN, Frenel, RAIFELD, Yuri, WEBER, Jennifer, BOSCHELLI, Frank
Published in Bioorganic & medicinal chemistry letters (21.10.2002)
Published in Bioorganic & medicinal chemistry letters (21.10.2002)
Get full text
Journal Article
Disodium (R,R)-5[2-[[2-γ(3-chlorophenyl)-2-hydroxyethyl]-amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate (CL 316,243). A potent β-adrenergic agonist virtually specific for β3 receptors. A promising antidiabetic and antiobesity agent
BLOOM, J. D, DUTIA, M. D, JOHNSON, B. D, WISSNER, A, BURNS, M. G, LARGIS, E. E, DOLAN, J. A, CLAUS, T. H
Published in Journal of medicinal chemistry (01.08.1992)
Published in Journal of medicinal chemistry (01.08.1992)
Get full text
Journal Article
BRIDGED, BICYCLIC HETEROCYCLIC OR SPIRO BICYCLIC HETEROCYCLIC DERIVATIVES OF PYRAZOLO[1,5-A]PYRIMIDINES, METHODS FOR PREPARATION AND USES THEREOF
TORRES NANCY, LEVIN JEREMY IAN, HOPPER DARRIN WILLIAM, WANG XIAOLUN, ZHANG CHUNCHUN, BERGER DAN MAARTEN, DUTIA MINU DHANJISH, DI GRANDI MARTIN JOSEPH, DUNNICK ALEJANDRO LEE
Year of Publication 24.11.2010
Get full text
Year of Publication 24.11.2010
Patent