Growth hormone receptor gene disruption in mature‐adult mice improves male insulin sensitivity and extends female lifespan
Duran‐Ortiz, Silvana, List, Edward O., Ikeno, Yuji, Young, Jonathan, Basu, Reetobrata, Bell, Stephen, McHugh, Todd, Funk, Kevin, Mathes, Samuel, Qian, Yanrong, Kulkarni, Prateek, Yakar, Shoshana, Berryman, Darlene E., Kopchick, John J.
Published in Aging cell (01.12.2021)
Published in Aging cell (01.12.2021)
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Journal Article
Induction of somatopause in adult mice compromises bone morphology and exacerbates bone loss during aging
Dixit, Manisha, Duran‐Ortiz, Silvana, Yildirim, Godze, Poudel, Sher Bahadur, Louis, Leeann D., Bartke, Andrzej, Schaffler, Mitchell B., Kopchick, John J., Yakar, Shoshana
Published in Aging cell (01.12.2021)
Published in Aging cell (01.12.2021)
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Journal Article
Differential gene signature in adipose tissue depots of growth hormone transgenic mice
Duran‐Ortiz, Silvana, Young, Jonathan A., Jara, Adam, Jensen, Elizabeth A., Basu, Reetobrata, List, Edward O., Qian, Yanrong, Kopchick, John J., Berryman, Darlene E.
Published in Journal of neuroendocrinology (01.11.2020)
Published in Journal of neuroendocrinology (01.11.2020)
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Journal Article
Lifelong Excess in GH Elicits Sexually Dimorphic Effects on Skeletal Morphology and Bone Mechanical Properties
Dixit, Manisha, Louis, Leeann D, Basta‐Pljakic, Jelena, Yildirim, Gozde, Poudel, Sher‐Bahadur, Kumararaja, Fancy, List, Edward O, Duran, Silvana Ortiz, Kopchick, John J, Ruff, Ryan R, Schaffler, Mitchell B, Yakar, Shoshana
Published in Journal of bone and mineral research (01.11.2022)
Published in Journal of bone and mineral research (01.11.2022)
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Journal Article
Musculoskeletal Effects of Altered GH Action
Young, Jonathan A, Zhu, Shouan, List, Edward O, Duran-Ortiz, Silvana, Slama, Yosri, Berryman, Darlene E
Published in Frontiers in physiology (19.05.2022)
Published in Frontiers in physiology (19.05.2022)
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Journal Article
Growth Hormone Receptor Antagonist Markedly Improves Gemcitabine Response in a Mouse Xenograft Model of Human Pancreatic Cancer
Basu, Reetobrata, Kulkarni, Prateek, Swegan, Deborah, Duran-Ortiz, Silvana, Ahmad, Arshad, Caggiano, Lydia J., Davis, Emily, Walsh, Christopher, Brenya, Edward, Koshal, Adeel, Brody, Rich, Sandbhor, Uday, Neggers, Sebastian J. C. M. M., Kopchick, John J.
Published in International journal of molecular sciences (01.07.2024)
Published in International journal of molecular sciences (01.07.2024)
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Journal Article
The Effects of 20-kDa Human Placental GH in Male and Female GH-deficient Mice: An Improved Human GH?
List, Edward O, Berryman, Darlene E, Basu, Reetobrata, Buchman, Mathew, Funk, Kevin, Kulkarni, Prateek, Duran-Ortiz, Silvana, Qian, Yanrong, Jensen, Elizabeth A, Young, Jonathan A, Yildirim, Gozde, Yakar, Shoshana, Kopchick, John J
Published in Endocrinology (Philadelphia) (01.08.2020)
Published in Endocrinology (Philadelphia) (01.08.2020)
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Journal Article
Growth hormone receptor antagonism downregulates ATP-binding cassette transporters contributing to improved drug efficacy against melanoma and hepatocarcinoma in vivo
Basu, Reetobrata, Qian, Yanrong, Mathes, Samuel, Terry, Joseph, Arnett, Nathan, Riddell, Trent, Stevens, Austin, Funk, Kevin, Bell, Stephen, Bokal, Zac, Batten, Courtney, Smith, Cole, Mendez-Gibson, Isaac, Duran-Ortiz, Silvana, Lach, Grace, Mora-Criollo, Patricia Alexandra, Kulkarni, Prateek, Davis, Emily, Teaford, Elizabeth, Berryman, Darlene E., List, Edward O., Neggers, Sebastian, Kopchick, John J.
Published in Frontiers in oncology (05.07.2022)
Published in Frontiers in oncology (05.07.2022)
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Journal Article
Growth Hormone Upregulates Mediators of Melanoma Drug Efflux and Epithelial-to-Mesenchymal Transition In Vitro and In Vivo
Qian, Yanrong, Basu, Reetobrata, Mathes, Samuel C, Arnett, Nathan A, Duran-Ortiz, Silvana, Funk, Kevin R, Brittain, Alison L, Kulkarni, Prateek, Terry, Joseph C, Davis, Emily, Singerman, Jordyn T, Henry, Brooke E, List, Edward O, Berryman, Darlene E, Kopchick, John J
Published in Cancers (04.12.2020)
Published in Cancers (04.12.2020)
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Journal Article
Growth Hormone Upregulates Melanocyte-Inducing Transcription Factor Expression and Activity via JAK2-STAT5 and SRC Signaling in GH Receptor-Positive Human Melanoma
Basu, Reetobrata, Kulkarni, Prateek, Qian, Yanrong, Walsh, Christopher, Arora, Pranay, Davis, Emily, Duran-Ortiz, Silvana, Funk, Kevin, Ibarra, Diego, Kruse, Colin, Mathes, Samuel, McHugh, Todd, Brittain, Alison, Berryman, Darlene E, List, Edward O, Okada, Shigeru, Kopchick, John J
Published in Cancers (12.09.2019)
Published in Cancers (12.09.2019)
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Journal Article
The impact of growth hormone on proteomic profiles: a review of mouse and adult human studies
Duran-Ortiz, Silvana, Brittain, Alison L, Kopchick, John J
Published in Clinical proteomics (29.06.2017)
Published in Clinical proteomics (29.06.2017)
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Journal Article
Growth Hormone Alters Circulating Levels of Glycine and Hydroxyproline in Mice
Young, Jonathan A, Duran-Ortiz, Silvana, Bell, Stephen, Funk, Kevin, Tian, Yuan, Liu, Qing, Patterson, Andrew D, List, Edward O, Berryman, Darlene E, Kopchick, John J
Published in Metabolites (28.01.2023)
Published in Metabolites (28.01.2023)
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Journal Article
Effects of tissue-specific GH receptor knockouts in mice
List, Edward O., Duran-Ortiz, Silvana, Kopchick, John J.
Published in Molecular and cellular endocrinology (15.09.2020)
Published in Molecular and cellular endocrinology (15.09.2020)
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Journal Article
Common and uncommon mouse models of growth hormone deficiency
List, Edward O, Basu, Reetobrata, Berryman, Darlene E, Duran-Ortiz, Silvana, Martos-Moreno, Gabriel Á, Kopchick, John J
Published in Endocrine reviews (10.06.2024)
Published in Endocrine reviews (10.06.2024)
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Journal Article
Extending lifespan by modulating the growth hormone/insulin-like growth factor-1 axis: coming of age
Duran-Ortiz, Silvana, List, Edward O., Basu, Reetobrata, Kopchick, John J.
Published in Pituitary (01.06.2021)
Published in Pituitary (01.06.2021)
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Journal Article
Disruption of Growth Hormone Receptor in Adipocytes Improves Insulin Sensitivity and Lifespan in Mice
List, Edward O, Berryman, Darlene E, Slyby, Julie, Duran-Ortiz, Silvana, Funk, Kevin, Bisset, Elise S, Howlett, Susan E, Kopchick, John J
Published in Endocrinology (Philadelphia) (01.10.2022)
Published in Endocrinology (Philadelphia) (01.10.2022)
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Journal Article
GH Knockout Mice Have Increased Subcutaneous Adipose Tissue With Decreased Fibrosis and Enhanced Insulin Sensitivity
List, Edward O, Berryman, Darlene E, Buchman, Mathew, Jensen, Elizabeth A, Funk, Kevin, Duran-Ortiz, Silvana, Qian, Yanrong, Young, Jonathan A, Slyby, Julie, McKenna, Savannah, Kopchick, John J
Published in Endocrinology (Philadelphia) (01.07.2019)
Published in Endocrinology (Philadelphia) (01.07.2019)
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Journal Article
Adipocyte-Specific GH Receptor–Null (AdGHRKO) Mice Have Enhanced Insulin Sensitivity With Reduced Liver Triglycerides
List, Edward O, Berryman, Darlene E, Buchman, Mathew, Parker, Caitlin, Funk, Kevin, Bell, Stephen, Duran-Ortiz, Silvana, Qian, Yanrong, Young, Jonathan A, Wilson, Cody, Slyby, Julie, McKenna, Savannah, Jensen, Elizabeth A, Kopchick, John J
Published in Endocrinology (Philadelphia) (01.01.2019)
Published in Endocrinology (Philadelphia) (01.01.2019)
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Journal Article
Lifelong excess in GH elicits sexual dimorphic effects on skeletal morphology and bone mechanical properties
Dixit, Manisha, Louis, Leeann D, Basta-Pljakic, Jelena, Yildirim, Gozde, Poudel, Sher-Bahadur, Kumararaja, Fancy, List, Edward O, Duran, Silvana Ortiz, Kopchick, John J, Ruff, Ryan R, Schaffler, Mitchell B, Yakar, Shoshana
Published in Journal of bone and mineral research (16.09.2022)
Published in Journal of bone and mineral research (16.09.2022)
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Journal Article