African polyvalent antivenom can maintain pharmacological stability and ability to neutralise murine venom lethality for decades post-expiry: evidence for increasing antivenom shelf life to aid in alleviating chronic shortages
Solano, Gabriela, Cunningham, Sinead, Edge, Rebecca J, Duran, Gina, Sanchez, Adriana, Villalta, Mauren, Clare, Rachel H, Wilkinson, Mark C, Marriott, Amy E, Abada, Camille, Menzies, Stefanie K, Keen, Molly, Lalloo, David G, Stienstra, Ymkje, Abouyannis, Michael, Casewell, Nicholas R, León, Guillermo, Ainsworth, Stuart
Published in BMJ global health (13.03.2024)
Published in BMJ global health (13.03.2024)
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Comparison of the intrageneric neutralization scope of monospecific, bispecific/monogeneric and polyspecific/monogeneric antisera raised in horses immunized with sub-Saharan African snake venoms
Sánchez, Andrés, Durán, Gina, Segura, Álvaro, Herrera, María, Vargas, Mariángela, Villalta, Mauren, Arguedas, Mauricio, Moscoso, Edwin, Umaña, Deibid, Gómez, Aarón, Gutiérrez, José María, León, Guillermo
Published in PLoS neglected tropical diseases (01.05.2024)
Published in PLoS neglected tropical diseases (01.05.2024)
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Intrageneric cross-reactivity of monospecific rabbit antisera against venoms of the medically most important Bitis spp. and Echis spp. African snakes
Gómez, Aarón, Sánchez, Andrés, Durán, Gina, Cordero, Daniel, Segura, Álvaro, Vargas, Mariángela, Solano, Daniela, Herrera, María, Chaves-Araya, Stephanie, Villalta, Mauren, Sánchez, Melvin, Arguedas, Mauricio, Díaz, Cecilia, Gutiérrez, José María, León, Guillermo
Published in PLoS neglected tropical diseases (01.08.2022)
Published in PLoS neglected tropical diseases (01.08.2022)
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Assessment of the Artemia salina toxicity assay as a substitute of the mouse lethality assay in the determination of venom-induced toxicity and preclinical efficacy of antivenom
Araya, Xavier, Okumu, Mitchel, Durán, Gina, Gómez, Aarón, Gutiérrez, José María, León, Guillermo
Published in Toxicon X (01.06.2024)
Published in Toxicon X (01.06.2024)
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Journal Article
Intrageneric cross-reactivity of monospecific rabbit antisera against venoms of the medically most important Naja spp. African snakes
Gómez, Aarón, Sánchez, Andrés, Durán, Gina, Villalta, Mauren, Segura, Álvaro, Vargas, Mariángela, Solano, Daniela, Herrera, María, Sánchez, Melvin, Gutiérrez, José María, León, Guillermo
Published in PLoS neglected tropical diseases (15.08.2023)
Published in PLoS neglected tropical diseases (15.08.2023)
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Intrageneric cross-reactivity of monospecific rabbit antisera against venoms of mamba (Elapidae: Dendroaspis spp.) snakes
Gómez, Aarón, Sánchez, Andrés, Durán, Gina, Villalta, Mauren, Segura, Álvaro, Vargas, Mariángela, Herrera, María, Sánchez, Melvin, Gutiérrez, José María, León, Guillermo
Published in Toxicon X (01.03.2024)
Published in Toxicon X (01.03.2024)
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Analysis of commercially available snake antivenoms reveals high contents of endotoxins in some products
Solano, Gabriela, Ainsworth, Stuart, Sánchez, Adriana, Villalta, Mauren, Sánchez, Paola, Durán, Gina, Gutiérrez, José María, León, Guillermo
Published in Toxicon X (01.03.2024)
Published in Toxicon X (01.03.2024)
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Assessing a 6-h endpoint observation time in the lethality neutralization assay used to evaluate the preclinical efficacy of snake antivenoms
Durán, Gina, Solano, Gabriela, Gómez, Aarón, Cordero, Daniel, Sánchez, Adriana, Villalta, Mauren, Sánchez, Melvin, Díaz, Cecilia, Gutiérrez, José María, León, Guillermo
Published in Toxicon X (01.11.2021)
Published in Toxicon X (01.11.2021)
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Comparison of adjuvant emulsions for their safety and ability to enhance the antibody response in horses immunized with African snake venoms
Arguedas, Mauricio, Umaña, Deibid, Moscoso, Edwin, García, Armando, Pereira, Carolina, Sánchez, Andrés, Durán, Gina, Cordero, Daniel, Sánchez, Adriana, Segura, Álvaro, Vargas, Mariángela, Herrera, María, Villalta, Mauren, Gómez, Aarón, Salas, Catalina, Díaz, Cecilia, María Gutiérrez, José, León, Guillermo
Published in Vaccine: X (01.12.2022)
Published in Vaccine: X (01.12.2022)
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Design, development and preclinical assessment of MENAVip-ICP, a new snake antivenom with potential coverage of species in the Middle East and North Africa regions
Segura, Álvaro, Moscoso, Edwin, Umaña, Deibid, Vargas, Mariángela, Sánchez, Andrés, Hernández, Andrés, Durán, Gina, Villalta, Mauren, Gómez, Aarón, Herrera, María, Arguedas, Mauricio, Gutiérrez, José María, León, Guillermo
Published in Toxicon X (01.12.2024)
Published in Toxicon X (01.12.2024)
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Stress levels, hematological condition, and productivity of plasma-producing horses used for snake antivenom manufacture: A comparison of two industrial bleeding methods
Arias-Esquivel, Ana Margarita, Moscoso, Edwin, Umaña, Deibid, Arguedas, Mauricio, Solano, Daniela, Durán, Gina, Gómez, Aarón, Gutiérrez, José María, León, Guillermo
Published in Toxicon X (01.12.2024)
Published in Toxicon X (01.12.2024)
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In vitro Characterization of Anti-SARS-CoV-2 Intravenous Immunoglobulins (IVIg) Produced From Plasma of Donors Immunized With the BNT162b2 Vaccine and Its Comparison With a Similar Formulation Produced From Plasma of COVID-19 Convalescent Donors
Rojas-Jiménez, Gabriel, Solano, Daniela, Segura, Álvaro, Sánchez, Andrés, Chaves-Araya, Stephanie, Herrera, María, Vargas, Mariángela, Cerdas, Maykel, Calvo, Gerardo, Alfaro, Jonathan, Molina, Sebastián, Bolaños, Kimberly, Moreira-Soto, Andrés, Villalta, Mauren, Sánchez, Adriana, Cordero, Daniel, Durán, Gina, Solano, Gabriela, Gómez, Aarón, Hernández, Andrés, Sánchez, Laura, Vargas, Marco, Drexler, Jean Felix, Alape-Girón, Alberto, Díaz, Cecilia, León, Guillermo
Published in Frontiers in medical technology (05.01.2022)
Published in Frontiers in medical technology (05.01.2022)
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Pilot-scale evaluation of a dynamic body-feed filtration system for primary clarification of snake antivenoms produced by the caprylic acid method
Sánchez, Andrés, Cerdas, Maykel, Gutiérrez, Jairo, Vargas, Mariángela, Segura, Álvaro, Herrera, María, Chaves-Araya, Stephanie, Sánchez, Ronald, Villalta, Mauren, Durán, Gina, Sánchez, Adriana, Solano, Gabriela, Cordero, Daniel, Sánchez, Paola, Gutiérrez, José María, León, Guillermo
Published in Toxicon X (01.09.2024)
Published in Toxicon X (01.09.2024)
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Journal Article
Assessment of the Artemia salina toxicity assay as a substitute of the mouse lethality assay in the determination of venom-induced toxicity and preclinical efficacy of antivenom
Araya, Xavier, Okumu, Mitchel, Durán, Gina, Gómez, Aarón, Gutiérrez, José María, León, Guillermo
Published in Toxicon (Oxford) (01.09.2024)
Published in Toxicon (Oxford) (01.09.2024)
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Journal Article
Comparison of the intrageneric neutralization scope of monospecific, bispecific/monogeneric and polyspecific/monogeneric antisera raised in horses immunized with sub-Saharan African snake venoms
Sánchez, Andrés, Durán, Gina, Segura, Álvaro, Herrera, María, Vargas, Mariángela, Villalta, Mauren, Arguedas, Mauricio, Moscoso, Edwin, Umaña, Deibid, Gómez, Aarón, Gutiérrez, José María, León, Guillermo
Published in Toxicon (Oxford) (01.09.2024)
Published in Toxicon (Oxford) (01.09.2024)
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Evaluacion de la capacidad de cuatro antivenenos comerciales para neutralizar el veneno de la serpiente Bothrops asper (terciopelo) de Costa Rica
Bogarín, Guisella, Segura, Eduardo, Durán, Gina, Lomonte, Bruno, Rojas, Gustavo, Gutiérrez, JoséMaría
Published in Toxicon (Oxford) (1995)
Published in Toxicon (Oxford) (1995)
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Development and pre-clinical characterization of two therapeutic equine formulations towards SARS-CoV-2 proteins for the potential treatment of COVID-19
León, Guillermo, Herrera, María, Vargas, Mariángela, Arguedas, Mauricio, Sánchez, Andrés, Segura, Álvaro, Gómez, Aarón, Solano, Gabriela, Corrales-Aguilar, Eugenia, Risner, Kenneth, Narayanan, Aarthi, Bailey, Charles, Villalta, Mauren, Hernández, Andrés, Sánchez, Adriana, Cordero, Daniel, Solano, Daniela, Durán, Gina, Segura, Eduardo, Maykel Cerdas, Umaña, Deibid, Moscoso, Edwin, Estrada, Ricardo, Gutiérrez, Jairo, Méndez, Marcos, Castillo, Ana Cecilia, Sánchez, Laura, Gutiérrez, José María, Díaz, Cecilia, Alape, Alberto
Published in bioRxiv (19.10.2020)
Published in bioRxiv (19.10.2020)
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Paper
Evaluación de la capacidad de cuatro antivenenos comerciales para neutralizar el veneno de la serpiente Bothrops asper (terciopelo) de Costa Rica
BOGARIN, G, SEGURA, E, DURAN, G, LOMONTE, B, ROJAS, G, GUTIERREZ, J. M
Published in Toxicon (Oxford) (01.09.1995)
Published in Toxicon (Oxford) (01.09.1995)
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Conference Proceeding
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