Molecular Tuning of Actin Dynamics in Leukocyte Migration as Revealed by Immune-Related Actinopathies
Kamnev, Anton, Lacouture, Claire, Fusaro, Mathieu, Dupré, Loïc
Published in Frontiers in immunology (15.11.2021)
Published in Frontiers in immunology (15.11.2021)
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Actin Dynamics at the T Cell Synapse as Revealed by Immune-Related Actinopathies
Dupré, Loïc, Boztug, Kaan, Pfajfer, Laurène
Published in Frontiers in cell and developmental biology (24.06.2021)
Published in Frontiers in cell and developmental biology (24.06.2021)
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LFA-1 nanoclusters integrate TCR stimulation strength to tune T-cell cytotoxic activity
Lacouture, Claire, Chaves, Beatriz, Guipouy, Delphine, Houmadi, Raïssa, Duplan-Eche, Valérie, Allart, Sophie, Destainville, Nicolas, Dupré, Loïc
Published in Nature communications (09.01.2024)
Published in Nature communications (09.01.2024)
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Lymphocyte migration and retention properties affected by ibrutinib in chronic lymphocytic leukemia
Rey-Barroso, Javier, Munaretto, Alice, Rouquié, Nelly, Mougel, Aurélie, Chassan, Malika, Gadat, Sébastien, Dewingle, Océane, Poincloux, Renaud, Cadot, Sarah, Ysebaert, Loïc, Quillet-Mary, Anne, Dupré, Loïc
Published in Haematologica (Roma) (01.03.2024)
Published in Haematologica (Roma) (01.03.2024)
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initial and rapid step of lytic granule secretion precedes microtubule organizing center polarization at the cytotoxic T lymphocyte/target cell synapse
Bertrand, Florie, Müller, Sabina, Roh, Kyung-Ho, Laurent, Camille, Dupré, Loïc, Valitutti, Salvatore
Published in Proceedings of the National Academy of Sciences - PNAS (09.04.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (09.04.2013)
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Mutations affecting the actin regulator WD repeat–containing protein 1 lead to aberrant lymphoid immunity
Pfajfer, Laurène, Mair, Nina K., Jiménez-Heredia, Raúl, Genel, Ferah, Gulez, Nesrin, Ardeniz, Ömür, Hoeger, Birgit, Bal, Sevgi Köstel, Madritsch, Christoph, Kalinichenko, Artem, Chandra Ardy, Rico, Gerçeker, Bengü, Rey-Barroso, Javier, Ijspeert, Hanna, Tangye, Stuart G., Simonitsch-Klupp, Ingrid, Huppa, Johannes B., van der Burg, Mirjam, Dupré, Loïc, Boztug, Kaan
Published in Journal of allergy and clinical immunology (01.11.2018)
Published in Journal of allergy and clinical immunology (01.11.2018)
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Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy
Weulersse, Marianne, Asrir, Assia, Pichler, Andrea C., Lemaitre, Lea, Braun, Matthias, Carrié, Nadège, Joubert, Marie-Véronique, Le Moine, Marie, Do Souto, Laura, Gaud, Guillaume, Das, Indrajit, Brauns, Elisa, Scarlata, Clara M., Morandi, Elena, Sundarrajan, Ashmitha, Cuisinier, Marine, Buisson, Laure, Maheo, Sabrina, Kassem, Sahar, Agesta, Arantxa, Pérès, Michaël, Verhoeyen, Els, Martinez, Alejandra, Mazieres, Julien, Dupré, Loïc, Gossye, Thomas, Pancaldi, Vera, Guillerey, Camille, Ayyoub, Maha, Dejean, Anne S., Saoudi, Abdelhadi, Goriely, Stanislas, Avet-Loiseau, Hervé, Bald, Tobias, Smyth, Mark J., Martinet, Ludovic
Published in Immunity (Cambridge, Mass.) (13.10.2020)
Published in Immunity (Cambridge, Mass.) (13.10.2020)
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Journal Article
Molecular Tuning of Filamin A Activities in the Context of Adhesion and Migration
Lamsoul, Isabelle, Dupré, Loïc, Lutz, Pierre G
Published in Frontiers in cell and developmental biology (20.11.2020)
Published in Frontiers in cell and developmental biology (20.11.2020)
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Journal Article
T-cell defects in patients with ARPC1B germline mutations account for combined immunodeficiency
Brigida, Immacolata, Zoccolillo, Matteo, Cicalese, Maria Pia, Pfajfer, Laurène, Barzaghi, Federica, Scala, Serena, Oleaga-Quintas, Carmen, Álvarez-Álvarez, Jesus A., Sereni, Lucia, Giannelli, Stefania, Sartirana, Claudia, Dionisio, Francesca, Pavesi, Luca, Benavides-Nieto, Marta, Basso-Ricci, Luca, Capasso, Paola, Mazzi, Benedetta, Rosain, Jeremie, Marcus, Nufar, Lee, Yu Nee, Somech, Raz, Degano, Massimo, Raiola, Giuseppe, Caorsi, Roberta, Picco, Paolo, Moncada Velez, Marcela, Khourieh, Joelle, Arias, Andrés Augusto, Bousfiha, Aziz, Issekutz, Thomas, Issekutz, Andrew, Boisson, Bertrand, Dobbs, Kerry, Villa, Anna, Lombardo, Angelo, Neven, Benedicte, Moshous, Despina, Casanova, Jean-Laurent, Franco, José Luis, Notarangelo, Luigi D., Scielzo, Cristina, Volpi, Stefano, Dupré, Loïc, Bustamante, Jacinta, Gattorno, Marco, Aiuti, Alessandro
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Coordinated ARP2/3 and glycolytic activities regulate the morphological and functional fitness of human CD8+ T cells
Kamnev, Anton, Mehta, Tanvi, Wielscher, Matthias, Chaves, Beatriz, Lacouture, Claire, Mautner, Anna-Katharina, Shaw, Lisa E., Caldera, Michael, Menche, Jörg, Weninger, Wolfgang P., Farlik, Matthias, Boztug, Kaan, Dupré, Loïc
Published in Cell reports (Cambridge) (26.03.2024)
Published in Cell reports (Cambridge) (26.03.2024)
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The Wiskott-Aldrich Syndrome Protein Contributes to the Assembly of the LFA-1 Nanocluster Belt at the Lytic Synapse
Houmadi, Raïssa, Guipouy, Delphine, Rey-Barroso, Javier, Vasconcelos, Zilton, Cornet, Julie, Manghi, Manoel, Destainville, Nicolas, Valitutti, Salvatore, Allart, Sophie, Dupré, Loïc
Published in Cell reports (Cambridge) (23.01.2018)
Published in Cell reports (Cambridge) (23.01.2018)
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EVER proteins, key elements of the natural anti-human papillomavirus barrier, are regulated upon T-cell activation
Lazarczyk, Maciej, Dalard, Cécile, Hayder, Myriam, Dupre, Loïc, Pignolet, Béatrice, Majewski, Slawomir, Vuillier, Francoise, Favre, Michel, Liblau, Roland S
Published in PloS one (28.06.2012)
Published in PloS one (28.06.2012)
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Altered Basal Lipid Metabolism Underlies the Functional Impairment of Naive CD8 + T Cells in Elderly Humans
Nicoli, Francesco, Cabral-Piccin, Mariela P, Papagno, Laura, Gallerani, Eleonora, Fusaro, Mathieu, Folcher, Victor, Dubois, Marion, Clave, Emmanuel, Vallet, Hélène, Frere, Justin J, Gostick, Emma, Llewellyn-Lacey, Sian, Price, David A, Toubert, Antoine, Dupré, Loïc, Boddaert, Jacques, Caputo, Antonella, Gavioli, Riccardo, Appay, Victor
Published in The Journal of immunology (1950) (01.02.2022)
Published in The Journal of immunology (1950) (01.02.2022)
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RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics
Salzer, Elisabeth, Cagdas, Deniz, Hons, Miroslav, Mace, Emily M, Garncarz, Wojciech, Petronczki, Özlem Yüce, Platzer, René, Pfajfer, Laurène, Bilic, Ivan, Ban, Sol A, Willmann, Katharina L, Mukherjee, Malini, Supper, Verena, Hsu, Hsiang Ting, Banerjee, Pinaki P, Sinha, Papiya, McClanahan, Fabienne, Zlabinger, Gerhard J, Pickl, Winfried F, Gribben, John G, Stockinger, Hannes, Bennett, Keiryn L, Huppa, Johannes B, Dupré, Loïc, Sanal, Özden, Jäger, Ulrich, Sixt, Michael, Tezcan, Ilhan, Orange, Jordan S, Boztug, Kaan
Published in Nature immunology (01.12.2016)
Published in Nature immunology (01.12.2016)
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Morphological profiling of human T and NK lymphocytes by high-content cell imaging
German, Yolla, Vulliard, Loan, Kamnev, Anton, Pfajfer, Laurène, Huemer, Jakob, Mautner, Anna-Katharina, Rubio, Aude, Kalinichenko, Artem, Boztug, Kaan, Ferrand, Audrey, Menche, Jörg, Dupré, Loïc
Published in Cell reports (Cambridge) (06.07.2021)
Published in Cell reports (Cambridge) (06.07.2021)
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R-loops cause genomic instability in T helper lymphocytes from patients with Wiskott-Aldrich syndrome
Sarkar, Koustav, Han, Seong-Su, Wen, Kuo-Kuang, Ochs, Hans D., Dupré, Loïc, Seidman, Michael M., Vyas, Yatin M.
Published in Journal of allergy and clinical immunology (01.07.2018)
Published in Journal of allergy and clinical immunology (01.07.2018)
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WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells
Marangoni, Francesco, Trifari, Sara, Scaramuzza, Samantha, Panaroni, Cristina, Martino, Silvana, Notarangelo, Luigi D, Baz, Zeina, Metin, Ayse, Cattaneo, Federica, Villa, Anna, Aiuti, Alessandro, Battaglia, Manuela, Roncarolo, Maria-Grazia, Dupré, Loïc
Published in The Journal of experimental medicine (19.02.2007)
Published in The Journal of experimental medicine (19.02.2007)
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Population Pharmacokinetics of Ibrutinib and Its Dihydrodiol Metabolite in Patients with Lymphoid Malignancies
Gallais, Fanny, Ysebaert, Loïc, Despas, Fabien, De Barros, Sandra, Dupré, Loïc, Quillet-Mary, Anne, Protin, Caroline, Thomas, Fabienne, Obéric, Lucie, Allal, Ben, Chatelut, Etienne, White-Koning, Mélanie
Published in Clinical pharmacokinetics (01.09.2020)
Published in Clinical pharmacokinetics (01.09.2020)
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