YB-1: oncoprotein, prognostic marker and therapeutic target?
Lasham, Annette, Print, Cristin G, Woolley, Adele G, Dunn, Sandra E, Braithwaite, Antony W
Published in Biochemical journal (01.01.2013)
Published in Biochemical journal (01.01.2013)
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Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress
Gurkar, Aditi U., Chu, Kiki, Raj, Lakshmi, Bouley, Richard, Lee, Seung-Hwan, Kim, Young-Bum, Dunn, Sandra E., Mandinova, Anna, Lee, Sam W.
Published in Nature communications (2013)
Published in Nature communications (2013)
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Phosphorylated Insulin-Like Growth Factor-I/Insulin Receptor Is Present in All Breast Cancer Subtypes and Is Related to Poor Survival
LAW, Jennifer H, HABIBI, Golareh, NICHOLSON, Robert I, CARBONI, Joan, GOTTARDIS, Marco, POLLAK, Michael, DUNN, Sandra E, KAIJI HU, MASOUDI, Hamid, WANG, Michelle Y. C, STRATFORD, Anna L, PARK, Eugene, GEE, Julia M. W, FINLAY, Pauline, JONES, Helen E
Published in Cancer research (Chicago, Ill.) (15.12.2008)
Published in Cancer research (Chicago, Ill.) (15.12.2008)
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YB-1 Expression and Phosphorylation Regulate Tumorigenicity and Invasiveness in Melanoma by Influencing EMT
Kosnopfel, Corinna, Sinnberg, Tobias, Sauer, Birgit, Busch, Christian, Niessner, Heike, Schmitt, Anja, Forchhammer, Stephan, Grimmel, Cornelia, Mertens, Peter R, Hailfinger, Stephan, Dunn, Sandra E, Garbe, Claus, Schittek, Birgit
Published in Molecular cancer research (01.07.2018)
Published in Molecular cancer research (01.07.2018)
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Inhibition of p90 ribosomal S6 kinases disrupts melanoma cell growth and immune evasion
Kosnopfel, Corinna, Wendlinger, Simone, Niessner, Heike, Siewert, Johannes, Sinnberg, Tobias, Hofmann, Angelika, Wohlfarth, Jonas, Schrama, David, Berthold, Marion, Siedel, Claudia, Sauer, Birgit, Jayanthan, Aarthi, Lenz, Georg, Dunn, Sandra E, Schilling, Bastian, Schittek, Birgit
Published in Journal of experimental & clinical cancer research (19.07.2023)
Published in Journal of experimental & clinical cancer research (19.07.2023)
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Y-Box Binding Protein-1 Induces the Expression of CD44 and CD49f Leading to Enhanced Self-Renewal, Mammosphere Growth, and Drug Resistance
TO, Karen, FOTOVATI, Abbas, RAOUF, Afshin, JOHNSON, Pauline, BERQUIN, Isabelle M, ROYER, Hans-Dieter, EAVES, Connie J, DUNN, Sandra E, REIPAS, Kristen M, LAW, Jennifer H, KAIJI HU, JING WANG, ASTANEHE, Arezoo, DAVIES, Alastair H, LEE, Lawrence, STRATFORD, Anna L
Published in Cancer research (Chicago, Ill.) (01.04.2010)
Published in Cancer research (Chicago, Ill.) (01.04.2010)
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Targeting p90 Ribosomal S6 Kinase Eliminates Tumor-Initiating Cells by Inactivating Y-Box Binding Protein-1 in Triple-Negative Breast Cancers
Stratford, Anna L., Reipas, Kristen, Hu, Kaiji, Fotovati, Abbas, Brough, Rachel, Frankum, Jessica, Takhar, Mandeep, Watson, Peter, Ashworth, Alan, Lord, Christopher J., Lasham, Annette, Print, Cristin G., Dunn, Sandra E.
Published in Stem cells (Dayton, Ohio) (01.07.2012)
Published in Stem cells (Dayton, Ohio) (01.07.2012)
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Interplay between YB-1 and IL-6 promotes the metastatic phenotype in breast cancer cells
Castellana, Bàrbara, Aasen, Trond, Moreno-Bueno, Gema, Dunn, Sandra E, Ramón y Cajal, Santiago
Published in Oncotarget (10.11.2015)
Published in Oncotarget (10.11.2015)
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YB‐1 Transforms Human Mammary Epithelial Cells Through Chromatin Remodeling Leading to the Development of Basal‐Like Breast Cancer
Davies, Alastair H., Reipas, Kristen M., Pambid, Mary Rose, Berns, Rachel, Stratford, Anna L., Fotovati, Abbas, Firmino, Natalie, Astanehe, Arezoo, Hu, Kaiji, Maxwell, Christopher, Mills, Gordon B., Dunn, Sandra E.
Published in Stem cells (Dayton, Ohio) (01.06.2014)
Published in Stem cells (Dayton, Ohio) (01.06.2014)
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Targeting YB-1 in HER-2 overexpressing breast cancer cells induces apoptosis via the mTOR/STAT3 pathway and suppresses tumor growth in mice
Lee, Cathy, Dhillon, Jaspreet, Wang, Michelle Y C, Gao, Yuanyuan, Hu, Kaiji, Park, Eugene, Astanehe, Arezoo, Hung, Mien-Chie, Eirew, Peter, Eaves, Connie J, Dunn, Sandra E
Published in Cancer research (Chicago, Ill.) (01.11.2008)
Published in Cancer research (Chicago, Ill.) (01.11.2008)
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Molecular Profiling Identifies Prognostic Subgroups of Pediatric Glioblastoma and Shows Increased YB-1 Expression in Tumors
FAURY, Damien, NANTEL, André, LOPEZ-AGUILAR, Enrique, VALERA, Elvis T, TONE, Luis G, CARRET, Anne-Sophie, DEL MAESTRO, Rolando F, GLEAVE, Martin, MONTES, Jose-Luis, PIETSCH, Torsten, ALBRECHT, Stephen, JABADO, Nada, DUNN, Sandra E, GUIOT, Marie-Christine, HAQUE, Takrima, HAUSER, Péter, GARAMI, Miklos, BOGNDR, Laszlo, HANZELY, Zoltan, LIBERSKI, Pawel P
Published in Journal of clinical oncology (01.04.2007)
Published in Journal of clinical oncology (01.04.2007)
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EZH2 expression is a prognostic factor in childhood intracranial ependymoma: A Canadian Pediatric Brain Tumor Consortium study
Li, Amanda M., Dunham, Christopher, Tabori, Uri, Carret, Anne‐Sophie, McNeely, P. Daniel, Johnston, Donna, Lafay‐Cousin, Lucie, Wilson, Beverly, Eisenstat, David D., Jabado, Nada, Zelcer, Shayna, Silva, Mariana, Scheinemann, Katrin, Fryer, Christopher, Hendson, Glenda, Fotovati, Abbas, Hawkins, Cynthia, Yip, Stephen, Dunn, Sandra E., Hukin, Juliette
Published in Cancer (01.05.2015)
Published in Cancer (01.05.2015)
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YB-1 Bridges Neural Stem Cells and Brain Tumor―Initiating Cells via Its Roles in Differentiation and Cell Growth
FOTOVATI, Abbas, ABU-ALI, Samah, UCHIUMI, Takeshi, KUWANO, Michihiko, LEAVITT, Blair R, SINGH, Sheila K, JURY, Alexa, JONES, Chris, WAKIMOTO, Hiroaki, REYNOLDS, Brent A, PALLEN, Catherine J, DUNN, Sandra E, WANG, Pei-Shan, DELEYROLLE, Loic P, LEE, Cathy, TRISCOTT, Joanna, CHEN, James Y, FRANCIOSI, Sonia, NAKAMURA, Yasuhiro, SUGITA, Yasuo
Published in Cancer research (Chicago, Ill.) (15.08.2011)
Published in Cancer research (Chicago, Ill.) (15.08.2011)
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Redefining prognostic factors for breast cancer: YB-1 is a stronger predictor of relapse and disease-specific survival than estrogen receptor or HER-2 across all tumor subtypes
Habibi, Golareh, Leung, Samuel, Law, Jennifer H, Gelmon, Karen, Masoudi, Hamid, Turbin, Dmitry, Pollak, Michael, Nielsen, Torsten O, Huntsman, David, Dunn, Sandra E
Published in Breast cancer research : BCR (01.01.2008)
Published in Breast cancer research : BCR (01.01.2008)
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Molecular decoy to the Y-box binding protein-1 suppresses the growth of breast and prostate cancer cells whilst sparing normal cell viability
Law, Jennifer H, Li, Yvonne, To, Karen, Wang, Michelle, Astanehe, Arezoo, Lambie, Karen, Dhillon, Jaspreet, Jones, Steven J M, Gleave, Martin E, Eaves, Connie J, Dunn, Sandra E
Published in PloS one (10.09.2010)
Published in PloS one (10.09.2010)
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Akt phosphorylates the Y-box binding protein 1 at Ser102 located in the cold shock domain and affects the anchorage-independent growth of breast cancer cells
SUTHERLAND, Brent W, KUCAB, Jill, LEIGHTON GRIMES, H, MILLER, Kathy, BADVE, Sunil, HUNTSMAN, David, BLAKE-GILKS, C, MIN CHEN, PALLEN, Catherine J, DUNN, Sandra E, WU, Joyce, LEE, Cathy, CHEANG, Maggie C. U, YORIDA, Erika, TURBIN, Dmitry, DEDHAR, Shoukat, NELSON, Colleen, POLLAK, Michael
Published in Oncogene (16.06.2005)
Published in Oncogene (16.06.2005)
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Disruption of the Y-box binding protein-1 results in suppression of the epidermal growth factor receptor and HER-2
WU, Joyce, LEE, Cathy, GILKS, C. Blake, DUNN, Sandra E, YOKOM, Daniel, JIANG, Helen, CHEANG, Maggie C. U, YORIDA, Erika, TURBIN, Dmitry, BERQUIN, Isabelle M, MERTENS, Peter R, IFTNER, Thomas
Published in Cancer research (Chicago, Ill.) (01.05.2006)
Published in Cancer research (Chicago, Ill.) (01.05.2006)
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Small interfering RNA library screen of human kinases and phosphatases identifies polo-like kinase 1 as a promising new target for the treatment of pediatric rhabdomyosarcomas
Hu, Kaiji, Lee, Cathy, Qiu, Dexin, Fotovati, Abbas, Davies, Alastair, Abu-Ali, Samah, Wai, Daniel, Lawlor, Elizabeth R, Triche, Timothy J, Pallen, Catherine J, Dunn, Sandra E
Published in Molecular cancer therapeutics (01.11.2009)
Published in Molecular cancer therapeutics (01.11.2009)
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Mechanisms underlying p53 regulation of PIK3CA transcription in ovarian surface epithelium and in ovarian cancer
Astanehe, Arezoo, Arenillas, David, Wasserman, Wyeth W, Leung, Peter C.K, Dunn, Sandra E, Davies, Barry R, Mills, Gordon B, Auersperg, Nelly
Published in Journal of cell science (01.03.2008)
Published in Journal of cell science (01.03.2008)
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