Hydroxyethylamine Based Phthalimides as New Class of Plasmepsin Hits: Design, Synthesis and Antimalarial Evaluation
Singh, Anil K, Rathore, Sumit, Tang, Yan, Goldfarb, Nathan E, Dunn, Ben M, Rajendran, Vinoth, Ghosh, Prahlad C, Singh, Neelu, Latha, N, Singh, Brajendra K, Rawat, Manmeet, Rathi, Brijesh
Published in PloS one (26.10.2015)
Published in PloS one (26.10.2015)
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Correction to “Inhibitor Complexes of the Pseudomonas Serine-Carboxyl Proteinase”
Wlodawer, Alexander, Li, Mi, Gustchina, Alla, Dauter, Zbigniew, Uchida, Kenichi, Oyama, Hiroshi, Goldfarb, Nathan E, Dunn, Ben M, Oda, Kohei
Published in Biochemistry (Easton) (13.11.2018)
Published in Biochemistry (Easton) (13.11.2018)
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Mycobacterium tuberculosis Hip1 modulates macrophage responses through proteolysis of GroEL2
Naffin-Olivos, Jacqueline L, Georgieva, Maria, Goldfarb, Nathan, Madan-Lala, Ranjna, Dong, Lauren, Bizzell, Erica, Valinetz, Ethan, Brandt, Gabriel S, Yu, Sarah, Shabashvili, Daniil E, Ringe, Dagmar, Dunn, Ben M, Petsko, Gregory A, Rengarajan, Jyothi
Published in PLoS pathogens (01.05.2014)
Published in PLoS pathogens (01.05.2014)
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Initial Cleavage of the Human Immunodeficiency Virus Type 1 GagPol Precursor by Its Activated Protease Occurs by an Intramolecular Mechanism
PETTIT, Steven C, EVERITT, Lorraine E, CHOUDHURY, Sumana, DUNN, Ben M, KAPLAN, Andrew H
Published in Journal of Virology (01.08.2004)
Published in Journal of Virology (01.08.2004)
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Enzymatic Characterization of Recombinant Food Vacuole Plasmepsin 4 from the Rodent Malaria Parasite Plasmodium berghei
Liu, Peng, Robbins, Arthur H, Marzahn, Melissa R, McClung, Scott H, Yowell, Charles A, Stevens, Jr, Stanley M, Dame, John B, Dunn, Ben M
Published in PloS one (28.10.2015)
Published in PloS one (28.10.2015)
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Exploring the scope of new arylamino alcohol derivatives: Synthesis, antimalarial evaluation, toxicological studies, and target exploration
Quiliano, Miguel, Mendoza, Adela, Fong, Kim Y., Pabón, Adriana, Goldfarb, Nathan E., Fabing, Isabelle, Vettorazzi, Ariane, López de Cerain, Adela, Dunn, Ben M., Garavito, Giovanny, Wright, David W., Deharo, Eric, Pérez-Silanes, Silvia, Aldana, Ignacio, Galiano, Silvia
Published in International journal for parasitology -- drugs and drug resistance (01.12.2016)
Published in International journal for parasitology -- drugs and drug resistance (01.12.2016)
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Catestatin, an endogenous Chromogranin A-derived peptide, inhibits in vitro growth of Plasmodium falciparum
Akaddar, Aziza, Doderer-Lang, Cécile, Marzahn, Melissa R, Delalande, François, Mousli, Marc, Helle, Karen, Van Dorsselaer, Alain, Aunis, Dominique, Dunn, Ben M, Metz-Boutigue, Marie-Hélène, Candolfi, Ermanno
Published in Cellular and molecular life sciences : CMLS (01.03.2010)
Published in Cellular and molecular life sciences : CMLS (01.03.2010)
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A Template-Based Approach to Inhibitors of Calpain 2, 20S Proteasome, and HIV-1 Protease
Jones, Seth A., Neilsen, Paul M., Siew, Limei, Callen, David F., Goldfarb, Nathan E., Dunn, Ben M., Abell, Andrew D.
Published in ChemMedChem (01.12.2013)
Published in ChemMedChem (01.12.2013)
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Analysis of HIV-1 CRF_01 A/E Protease Inhibitor Resistance: Structural Determinants for Maintaining Sensitivity and Developing Resistance to Atazanavir
Clemente, José C, Coman, Roxana M, Thiaville, Michele M, Janka, Linda K, Jeung, Jennifer A, Nukoolkarn, Sarawut, Govindasamy, Lakshmanan, Agbandje-McKenna, Mavis, McKenna, Robert, Leelamanit, Wichet, Goodenow, Maureen M, Dunn, Ben M
Published in Biochemistry (Easton) (02.05.2006)
Published in Biochemistry (Easton) (02.05.2006)
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Structural and biochemical characterization of the inhibitor complexes of xenotropic murine leukemia virus‐related virus protease
Li, Mi, Gustchina, Alla, Matúz, Krisztina, Tözsér, Jozsef, Namwong, Sirilak, Goldfarb, Nathan E., Dunn, Ben M., Wlodawer, Alexander
Published in The FEBS journal (01.11.2011)
Published in The FEBS journal (01.11.2011)
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Comparing the Accumulation of Active- and Nonactive-Site Mutations in the HIV-1 Protease
Clemente, José C, Moose, Rebecca E, Hemrajani, Reena, Whitford, Lisa R. S, Govindasamy, Lakshmanan, Reutzel, Robbie, McKenna, Robert, Agbandje-McKenna, Mavis, Goodenow, Maureen M, Dunn, Ben M
Published in Biochemistry (Easton) (28.09.2004)
Published in Biochemistry (Easton) (28.09.2004)
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Drug-associated changes in amino acid residues in Gag p2, p7NC , and p6Gag /p6Pol in human immunodeficiency virus type 1 (HIV-1) display a dominant effect on replicative fitness and drug response
Ho, Sarah K, Coman, Roxana M, Bunger, Joshua C, Rose, Stephanie L, O'Brien, Patricia, Munoz, Isabel, Dunn, Ben M, Sleasman, John W, Goodenow, Maureen M
Published in Virology (New York, N.Y.) (01.09.2008)
Published in Virology (New York, N.Y.) (01.09.2008)
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Recombinant Plasmepsin 1 from the Human Malaria Parasite Plasmodium falciparum: Enzymatic Characterization, Active Site Inhibitor Design, and Structural Analysis
Liu, Peng, Marzahn, Melissa R, Robbins, Arthur H, Gutiérrez-de-Terán, Hugo, Rodríguez, David, McClung, Scott H, Stevens, Stanley M, Yowell, Charles A, Dame, John B, McKenna, Robert, Dunn, Ben M
Published in Biochemistry (Easton) (19.05.2009)
Published in Biochemistry (Easton) (19.05.2009)
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Computational analysis of plasmepsin IV bound to an allophenylnorstatine inhibitor
Gutiérrez-de-Terán, Hugo, Nervall, Martin, Dunn, Ben M., Clemente, Jose C., Åqvist, Johan
Published in FEBS letters (30.10.2006)
Published in FEBS letters (30.10.2006)
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