Impaired Amino Acid Transport at the Blood Brain Barrier Is a Cause of Autism Spectrum Disorder
Tărlungeanu, Dora C., Deliu, Elena, Dotter, Christoph P., Kara, Majdi, Janiesch, Philipp Christoph, Scalise, Mariafrancesca, Galluccio, Michele, Tesulov, Mateja, Morelli, Emanuela, Sonmez, Fatma Mujgan, Bilguvar, Kaya, Ohgaki, Ryuichi, Kanai, Yoshikatsu, Johansen, Anide, Esharif, Seham, Ben-Omran, Tawfeg, Topcu, Meral, Schlessinger, Avner, Indiveri, Cesare, Duncan, Kent E., Caglayan, Ahmet Okay, Gunel, Murat, Gleeson, Joseph G., Novarino, Gaia
Published in Cell (01.12.2016)
Published in Cell (01.12.2016)
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Journal Article
Emerging Evidence of Translational Control by AU-Rich Element-Binding Proteins
Otsuka, Hiroshi, Fukao, Akira, Funakami, Yoshinori, Duncan, Kent E, Fujiwara, Toshinobu
Published in Frontiers in genetics (02.05.2019)
Published in Frontiers in genetics (02.05.2019)
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Journal Article
DENR–MCT-1 promotes translation re-initiation downstream of uORFs to control tissue growth
Schleich, Sibylle, Strassburger, Katrin, Janiesch, Philipp Christoph, Koledachkina, Tatyana, Miller, Katharine K., Haneke, Katharina, Cheng, Yong-Sheng, Küchler, Katrin, Stoecklin, Georg, Duncan, Kent E., Teleman, Aurelio A.
Published in Nature (London) (14.08.2014)
Published in Nature (London) (14.08.2014)
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Ubiquitin C-terminal hydrolase L1 (UCH-L1) loss causes neurodegeneration by altering protein turnover in the first postnatal weeks
Reinicke, Anna T., Laban, Karoline, Sachs, Marlies, Kraus, Vanessa, Walden, Michael, Damme, Markus, Sachs, Wiebke, Reichelt, Julia, Schweizer, Michaela, Janiesch, Philipp Christoph, Duncan, Kent E., Saftig, Paul, Rinschen, Markus M., Morellini, Fabio, Meyer-Schwesinger, Catherine
Published in Proceedings of the National Academy of Sciences - PNAS (16.04.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (16.04.2019)
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TDP-43 enhances translation of specific mRNAs linked to neurodegenerative disease
Neelagandan, Nagammal, Gonnella, Giorgio, Dang, Stefan, Janiesch, Philipp C, Miller, Katharine K, Küchler, Katrin, Marques, Rita F, Indenbirken, Daniela, Alawi, Malik, Grundhoff, Adam, Kurtz, Stefan, Duncan, Kent E
Published in Nucleic acids research (10.01.2019)
Published in Nucleic acids research (10.01.2019)
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Journal Article
Bassoon proteinopathy drives neurodegeneration in multiple sclerosis
Schattling, Benjamin, Engler, Jan Broder, Volkmann, Constantin, Rothammer, Nicola, Woo, Marcel S., Petersen, Meike, Winkler, Iris, Kaufmann, Max, Rosenkranz, Sina C., Fejtova, Anna, Thomas, Ulrich, Bose, Aparajita, Bauer, Simone, Träger, Simone, Miller, Katharine K., Brück, Wolfgang, Duncan, Kent E., Salinas, Gabriela, Soba, Peter, Gundelfinger, Eckart D., Merkler, Doron, Friese, Manuel A.
Published in Nature neuroscience (01.06.2019)
Published in Nature neuroscience (01.06.2019)
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ARE-binding protein ZFP36L1 interacts with CNOT1 to directly repress translation via a deadenylation-independent mechanism
Otsuka, Hiroshi, Fukao, Akira, Tomohiro, Takumi, Adachi, Shungo, Suzuki, Toru, Takahashi, Akinori, Funakami, Yoshinori, Natsume, Toru, Yamamoto, Tadashi, Duncan, Kent E., Fujiwara, Toshinobu
Published in Biochimie (01.07.2020)
Published in Biochimie (01.07.2020)
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Corrigendum: Emerging Evidence of Translational Control by AU-Rich Element-Binding Proteins
Otsuka, Hiroshi, Fukao, Akira, Funakami, Yoshinori, Duncan, Kent E., Fujiwara, Toshinobu
Published in Frontiers in genetics (28.06.2021)
Published in Frontiers in genetics (28.06.2021)
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Journal Article
Motor neuron translatome reveals deregulation of SYNGR4 and PLEKHB1 in mutant TDP-43 amyotrophic lateral sclerosis models
Marques, Rita F, Engler, Jan B, Küchler, Katrin, Jones, Ross A, Lingner, Thomas, Salinas, Gabriela, Gillingwater, Thomas H, Friese, Manuel A, Duncan, Kent E
Published in Human molecular genetics (29.09.2020)
Published in Human molecular genetics (29.09.2020)
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Journal Article
The SLC36 transporter Pathetic is required for extreme dendrite growth in Drosophila sensory neurons
Lin, Wen-Yang, Williams, Claire, Yan, Connie, Koledachkina, Tatyana, Luedke, Kory, Dalton, Jesse, Bloomsburg, Sam, Morrison, Nicole, Duncan, Kent E, Kim, Charles C, Parrish, Jay Z
Published in Genes & development (01.06.2015)
Published in Genes & development (01.06.2015)
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De Novo Mutations in DENR Disrupt Neuronal Development and Link Congenital Neurological Disorders to Faulty mRNA Translation Re-initiation
Haas, Matilda A., Ngo, Linh, Li, Shan Shan, Schleich, Sibylle, Qu, Zhengdong, Vanyai, Hannah K., Cullen, Hayley D., Cardona-Alberich, Aida, Gladwyn-Ng, Ivan E., Pagnamenta, Alistair T., Taylor, Jenny C., Stewart, Helen, Kini, Usha, Duncan, Kent E., Teleman, Aurelio A., Keays, David A., Heng, Julian I.-T.
Published in Cell reports (Cambridge) (07.06.2016)
Published in Cell reports (Cambridge) (07.06.2016)
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Nuclear Pore Components Are Involved in the Transcriptional Regulation of Dosage Compensation in Drosophila
Mendjan, Sascha, Taipale, Mikko, Kind, Jop, Holz, Herbert, Gebhardt, Philipp, Schelder, Malgorzata, Vermeulen, Michiel, Buscaino, Alessia, Duncan, Kent, Mueller, Juerg, Wilm, Matthias, Stunnenberg, Henk G., Saumweber, Harald, Akhtar, Asifa
Published in Molecular cell (17.03.2006)
Published in Molecular cell (17.03.2006)
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Pum2 and TDP-43 refine area-specific cytoarchitecture post-mitotically and modulate translation of Sox5, Bcl11b , and Rorb mRNAs in developing mouse neocortex
Harb, Kawssar, Richter, Melanie, Neelagandan, Nagammal, Magrinelli, Elia, Harfoush, Hend, Kuechler, Katrin, Henis, Melad, Hermanns-Borgmeyer, Irm, Calderon de Anda, Froylan, Duncan, Kent
Published in eLife (09.03.2022)
Published in eLife (09.03.2022)
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Journal Article
Drosophila miR2 primarily targets the m7GpppN cap structure for translational repression
Zdanowicz, Agnieszka, Thermann, Rolf, Kowalska, Joanna, Jemielity, Jacek, Duncan, Kent, Preiss, Thomas, Darzynkiewicz, Edward, Hentze, Matthias W
Published in Molecular cell (24.09.2009)
Published in Molecular cell (24.09.2009)
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A novel mouse model for inhibition of DOHH-mediated hypusine modification reveals a crucial function in embryonic development, proliferation and oncogenic transformation
Sievert, Henning, Pällmann, Nora, Miller, Katharine K, Hermans-Borgmeyer, Irm, Venz, Simone, Sendoel, Ataman, Preukschas, Michael, Schweizer, Michaela, Boettcher, Steffen, Janiesch, P Christoph, Streichert, Thomas, Walther, Reinhard, Hengartner, Michael O, Manz, Markus G, Brümmendorf, Tim H, Bokemeyer, Carsten, Braig, Melanie, Hauber, Joachim, Duncan, Kent E, Balabanov, Stefan
Published in Disease models & mechanisms (01.08.2014)
Published in Disease models & mechanisms (01.08.2014)
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Journal Article
The autism susceptibility kinase, TAOK2, phosphorylates eEF2 and modulates translation
Henis, Melad, Rücker, Tabitha, Scharrenberg, Robin, Richter, Melanie, Baltussen, Lucas, Hong, Shuai, Meka, Durga Praveen, Schwanke, Birgit, Neelagandan, Nagammal, Daaboul, Danie, Murtaza, Nadeem, Krisp, Christoph, Harder, Sönke, Schlüter, Hartmut, Kneussel, Matthias, Hermans-Borgmeyer, Irm, de Wit, Joris, Singh, Karun K, Duncan, Kent E, de Anda, Froylan Calderón
Published in Science advances (12.04.2024)
Published in Science advances (12.04.2024)
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Automated high-throughput RNAi screening in human cells combined with reporter mRNA transfection to identify novel regulators of translation
Casanova, Claudia M, Sehr, Peter, Putzker, Kerstin, Hentze, Matthias W, Neumann, Beate, Duncan, Kent E, Thoma, Christian
Published in PloS one (27.09.2012)
Published in PloS one (27.09.2012)
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Journal Article
Translation of Hepatitis A Virus IRES Is Upregulated by a Hepatic Cell-Specific Factor
Sadahiro, Akitoshi, Fukao, Akira, Kosaka, Mio, Funakami, Yoshinori, Takizawa, Naoki, Takeuchi, Osamu, Duncan, Kent E, Fujiwara, Toshinobu
Published in Frontiers in genetics (10.08.2018)
Published in Frontiers in genetics (10.08.2018)
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