Tebentafusp: T Cell Redirection for the Treatment of Metastatic Uveal Melanoma
Damato, Bertil E, Dukes, Joseph, Goodall, Howard, Carvajal, Richard D
Published in Cancers (11.07.2019)
Published in Cancers (11.07.2019)
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An approved in vitro approach to preclinical safety and efficacy evaluation of engineered T cell receptor anti-CD3 bispecific (ImmTAC) molecules
Harper, Jane, Adams, Katherine J, Bossi, Giovanna, Wright, Debbie E, Stacey, Andrea R, Bedke, Nicole, Martinez-Hague, Ruth, Blat, Dan, Humbert, Laure, Buchanan, Hazel, Le Provost, Gabrielle S, Donnellan, Zoe, Carreira, Ricardo J, Paston, Samantha J, Weigand, Luise U, Canestraro, Martina, Sanderson, Joseph P, Botta Gordon-Smith, Sophie, Lowe, Kate L, Rygiel, Karolina A, Powlesland, Alex S, Vuidepot, Annelise, Hassan, Namir J, Cameron, Brian J, Jakobsen, Bent K, Dukes, Joseph
Published in PloS one (15.10.2018)
Published in PloS one (15.10.2018)
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Proceedings of the inaugural Dark Genome Symposium: November 2022
Boeke, Jef D, Burns, Kathleen H, Chiappinelli, Katherine B, Classon, Marie, Coffin, John M, DeCarvalho, Daniel D, Dukes, Joseph D, Greenbaum, Benjamin, Kassiotis, George, Knutson, Sarah K, Levine, Arnold J, Nath, Avindra, Papa, Sophie, Rios, Daniel, Sedivy, John, Ting, David T
Published in Mobile DNA (21.11.2023)
Published in Mobile DNA (21.11.2023)
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A dominant-negative ESCRT-III protein perturbs cytokinesis and trafficking to lysosomes
Dukes, Joseph D, Richardson, Judith D, Simmons, Ruth, Whitley, Paul
Published in Biochemical journal (15.04.2008)
Published in Biochemical journal (15.04.2008)
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362 Allelic variants of MR1 drive cancer and allo-reactivity by MR1-restricted T cells
Howie, Duncan, Cornforth, Terri V, Moyo, Nathifa, Cole, Suzanne, Lam, Emily, Lobry, Tatiana, Wolchinsky, Ron, Lloyd, Angharad, Ward, Katarzyna, Denham, Eleanor M, Besra, Gurdyal S, Illing, Patricia, MacLachlan, Bruce, Vivian, Julian, Raynes, Jeremy, Nours, Jerome Le, Purcell, Anthony, Kundu, Samit, Silk, Jonathan D, Williams, Luke, Papa, Sophie, Rossjohn, Jamie, Dukes, Joseph
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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The secreted Salmonella dublin phosphoinositide phosphatase, SopB, localizes to PtdIns(3)P-containing endosomes and perturbs normal endosome to lysosome trafficking
Dukes, Joseph D, Lee, Huailo, Hagen, Rachel, Reaves, Barbara J, Layton, Abigail N, Galyov, Edouard E, Whitley, Paul
Published in Biochemical journal (15.04.2006)
Published in Biochemical journal (15.04.2006)
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Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma
Linette, Gerald P., Stadtmauer, Edward A., Maus, Marcela V., Rapoport, Aaron P., Levine, Bruce L., Emery, Lyndsey, Litzky, Leslie, Bagg, Adam, Carreno, Beatriz M., Cimino, Patrick J., Binder-Scholl, Gwendolyn K., Smethurst, Dominic P., Gerry, Andrew B., Pumphrey, Nick J., Bennett, Alan D., Brewer, Joanna E., Dukes, Joseph, Harper, Jane, Tayton-Martin, Helen K., Jakobsen, Bent K., Hassan, Namir J., Kalos, Michael, June, Carl H.
Published in Blood (08.08.2013)
Published in Blood (08.08.2013)
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Identification of a Titin-derived HLA-A1-presented peptide as a cross-reactive target for engineered MAGE A3-directed T cells
Cameron, Brian J, Gerry, Andrew B, Dukes, Joseph, Harper, Jane V, Kannan, Vivekanandan, Bianchi, Frayne C, Grand, Francis, Brewer, Joanna E, Gupta, Minnal, Plesa, Gabriela, Bossi, Giovanna, Vuidepot, Annelise, Powlesland, Alex S, Legg, Alison, Adams, Katherine J, Bennett, Alan D, Pumphrey, Nicholas J, Williams, Daniel D, Binder-Scholl, Gwendolyn, Kulikovskaya, Irina, Levine, Bruce L, Riley, James L, Varela-Rohena, Angel, Stadtmauer, Edward A, Rapoport, Aaron P, Linette, Gerald P, June, Carl H, Hassan, Namir J, Kalos, Michael, Jakobsen, Bent K
Published in Science translational medicine (07.08.2013)
Published in Science translational medicine (07.08.2013)
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Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy
Raman, Marine C C, Rizkallah, Pierre J, Simmons, Ruth, Donnellan, Zoe, Dukes, Joseph, Bossi, Giovanna, Le Provost, Gabrielle S, Todorov, Penio, Baston, Emma, Hickman, Emma, Mahon, Tara, Hassan, Namir, Vuidepot, Annelise, Sami, Malkit, Cole, David K, Jakobsen, Bent K
Published in Scientific reports (13.01.2016)
Published in Scientific reports (13.01.2016)
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TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide-HLA Complex
Coles, Charlotte H, Mulvaney, Rachel M, Malla, Sunir, Walker, Andrew, Smith, Kathrine J, Lloyd, Angharad, Lowe, Kate L, McCully, Michelle L, Martinez Hague, Ruth, Aleksic, Milos, Harper, Jane, Paston, Samantha J, Donnellan, Zoe, Chester, Fiona, Wiederhold, Katrin, Robinson, Ross A, Knox, Andrew, Stacey, Andrea R, Dukes, Joseph, Baston, Emma, Griffin, Sue, Jakobsen, Bent K, Vuidepot, Annelise, Harper, Stephen
Published in The Journal of immunology (1950) (01.04.2020)
Published in The Journal of immunology (1950) (01.04.2020)
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Journal Article
An approved in vitro approach to preclinical safety and efficacy evaluation of engineered T cell receptor anti-CD3 bispecific
Harper, Jane, Adams, Katherine J, Bossi, Giovanna, Wright, Debbie E, Stacey, Andrea R, Bedke, Nicole, Martinez-Hague, Ruth, Blat, Dan, Humbert, Laure, Buchanan, Hazel, Le Provost, Gabrielle S, Donnellan, Zoe, Carreira, Ricardo J, Paston, Samantha J, Weigand, Luise U, Canestraro, Martina, Sanderson, Joseph P, Botta Gordon-Smith, Sophie, Lowe, Kate L, Rygiel, Karolina A, Powlesland, Alex S, Vuidepot, Annelise, Hassan, Namir J, Cameron, Brian J, Jakobsen, Bent K, Dukes, Joseph
Published in PloS one (15.10.2018)
Published in PloS one (15.10.2018)
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343 Identification of tumor-reactive T cells targeting melanoma Dark Antigens™ validates this novel class of targets for development of immunotherapies
Abbott, Rachel, Hofland, Tom, Hulen, Thomas, Elizabeth (Els) Verdegaal, Crowther, Michael, Dukes, Joseph, Khan, Shawez, Pita de Kok, Masi, Giulia, Özcan Met, Schina, Aimilia, Selvadurai, Hayden, Visser, Marten, Ward, Katarzyna, van der Burg, Sjoerd, Kassiotis, George, Svane, Inge
Published in Journal for immunotherapy of cancer (01.11.2022)
Published in Journal for immunotherapy of cancer (01.11.2022)
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312 Identification of novel NSC lung cancer Dark Antigens™ with expression in multiple tumor types, as promising targets for immunotherapies
Abbott, Rachel, Alassadi, Okba, Davies, Matthew, Magdalena Von Essen, Freire-Benéitez, Verónica, Jefferson, Vicki, Kundu, Samit, Kurupati, Prathiba, Leonhardt, Ralf, Lukowski, Samuel, Marino, Fabio, Masi, Giulia, Rayner Queiroz, Selvadurai, Hayden, Senra, Joana, Tye, Emily, Dukes, Joseph
Published in Journal for immunotherapy of cancer (01.11.2022)
Published in Journal for immunotherapy of cancer (01.11.2022)
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Journal Article
Abstract 4873: ImmTACs re-direct the immune system efficiently to eradicate cancer
Bossi, Giovanna, Kenefeck, Rupert, Caroline Boudousquie, Caroline, Harper, Jane, Dukes, Joseph, Liddy, Nathaniel, Paston, Samantha, Mahon, Tara, Molloy, Peter, Sami, Malkit, Baston, Emma, Cameron, Brian, Vuidepot, Annelise, Hassan, Namir, Jakobsen, Bent K.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Abstract 4872: Developing high affinity, soluble T cell receptors for the treatment of cancer
Knox, Andrew, Chester, Fiona, Bianchi, Frayne, Bailey, Sarah, Bouard, Lucie, Liddy, Nathaniel, Bossi, Giovanna, Harper, Jane, Dukes, Joseph, Paston, Samantha, Mahon, Tara, Gavarret, Jessie, Molloy, Peter, Sami, Malkit, Baston, Emma, Cameron, Brian, Powlesland, Alex, Todorov, Penio, Johnson, Andrew, Ebner, Martin, McGrath, Yvonne, Hassan, Namir, Vuidepot, Annelise, Jakobsen, Bent
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Abstract 2900: IMCgp100: A novel bi-specific biologic for the treatment of malignant melanoma
Hassan, Namir J., Bossi, Giovanna, Baker, Debbie, Adams, Katherine, Harper, Jane, Dukes, Joseph, Liddy, Nathaniel, Paston, Samantha, McGrath, Yvonne, Mahon, Tara, Molloy, Peter, Sami, Malkit, Baston, Emma, Cameron, Brian, Johnson, Andrew, Vuidepot, Annelise, Linette, Gerry, Kalos, Michael, June, Carl, Jakobsen, Bent
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Abstract 2805: Cancer-specific T cell receptor isolation for cancer immunotherapy
Weigand, Luise U., Paston, Samantha, Hibbert, Linda, Ryan, Ruth K., Baker, Debbie E., Simmons, Ruth A., Harper, Jane V., Dukes, Joseph D., Bossi, Giovanna, Grand, Francis, Hickman, Emma, Powlesland, Alex, Vuidepot, Annelise, Hassan, Namir J., Jakobsen, Bent K.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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