The HIV-1 Nucleocapsid Regulates Its Own Condensation by Phase-Separated Activity-Enhancing Sequestration of the Viral Protease during Maturation
Lyonnais, Sébastien, Sadiq, S Kashif, Lorca-Oró, Cristina, Dufau, Laure, Nieto-Marquez, Sara, Escribà, Tuixent, Gabrielli, Natalia, Tan, Xiao, Ouizougun-Oubari, Mohamed, Okoronkwo, Josephine, Reboud-Ravaux, Michèle, Gatell, José Maria, Marquet, Roland, Paillart, Jean-Christophe, Meyerhans, Andreas, Tisné, Carine, Gorelick, Robert J, Mirambeau, Gilles
Published in Viruses (19.11.2021)
Published in Viruses (19.11.2021)
Get full text
Journal Article
Dimerized Linear Mimics of a Natural Cyclopeptide (TMC-95A) Are Potent Noncovalent Inhibitors of the Eukaryotic 20S Proteasome
Desvergne, Audrey, Genin, Emilie, Maréchal, Xavier, Gallastegui, Nerea, Dufau, Laure, Richy, Nicolas, Groll, Michael, Vidal, Joëlle, Reboud-Ravaux, Michèle
Published in Journal of medicinal chemistry (25.04.2013)
Published in Journal of medicinal chemistry (25.04.2013)
Get full text
Journal Article
New C-4-and C-1-derivatives of furo[3,4-c] pyridine-3-ones and related compounds: Evidence for site-specific inhibition of the constitutive proteasome and its immunoisoform
Hovhannisyan, Anna, The Hien Pham, Bouvier, Dominique, Piroyan, Alexander, Dufau, Laure, Qin, Lixian, Cheng, Yan, Melikyan, Gagik, Reboud-Ravaux, Michele, Bouvier-Durand, Michelle
Published in Bioorganic & medicinal chemistry letters (15.03.2014)
Published in Bioorganic & medicinal chemistry letters (15.03.2014)
Get full text
Journal Article
New C(4)- and C(1)-derivatives of furo[3,4-c]pyridine-3-ones and related compounds: evidence for site-specific inhibition of the constitutive proteasome and its immunoisoform
Hovhannisyan, Anna, Pham, The Hien, Bouvier, Dominique, Piroyan, Alexander, Dufau, Laure, Qin, Lixian, Cheng, Yan, Melikyan, Gagik, Reboud-Ravaux, Michèle, Bouvier-Durand, Michelle
Published in Bioorganic & medicinal chemistry letters (15.03.2014)
Published in Bioorganic & medicinal chemistry letters (15.03.2014)
Get full text
Journal Article
α- and β-hydrazino acid-based pseudopeptides inhibit the chymotrypsin-like activity of the eukaryotic 20S proteasome
Bordessa, Andrea, Keita, Massaba, Maréchal, Xavier, Formicola, Lucia, Lagarde, Nathalie, Rodrigo, Jordi, Bernadat, Guillaume, Bauvais, Cyril, Soulier, Jean-Louis, Dufau, Laure, Milcent, Thierry, Crousse, Benoit, Reboud-Ravaux, Michèle, Ongeri, Sandrine
Published in European journal of medicinal chemistry (01.12.2013)
Published in European journal of medicinal chemistry (01.12.2013)
Get full text
Journal Article
Bisbenzimidazole derivatives as potent inhibitors of the trypsin-like sites of the immunoproteasome core particle
Koroleva, Olga N., Pham, The Hien, Bouvier, Dominique, Dufau, Laure, Qin, Lixian, Reboud-Ravaux, Michèle, Ivanov, Alexander A., Zhuze, Alexei L., Gromova, Elizaveta S., Bouvier-Durand, Michelle
Published in Biochimie (01.01.2015)
Published in Biochimie (01.01.2015)
Get full text
Journal Article
New C4- and C1-derivatives of furo[3,4-c]pyridine-3-ones and related compounds: Evidence for site-specific inhibition of the constitutive proteasome and its immunoisoform
Hovhannisyan, Anna, Pham, The Hien, Bouvier, Dominique, Piroyan, Alexander, Dufau, Laure, Qin, Lixian, Cheng, Yan, Melikyan, Gagik, Reboud-Ravaux, Michèle, Bouvier-Durand, Michelle
Published in Bioorganic & medicinal chemistry letters (15.03.2014)
Published in Bioorganic & medicinal chemistry letters (15.03.2014)
Get full text
Journal Article
New C super(4)- and C super(1)-derivatives of furo[3,4-c]pyridine-3-ones and related compounds: Evidence for site-specific inhibition of the constitutive proteasome and its immunoisoform
Hovhannisyan, Anna, Pham, The Hien, Bouvier, Dominique, Piroyan, Alexander, Dufau, Laure, Qin, Lixian, Cheng, Yan, Melikyan, Gagik, Reboud-Ravaux, Michele, Bouvier-Durand, Michelle
Published in Bioorganic & medicinal chemistry letters (01.03.2014)
Published in Bioorganic & medicinal chemistry letters (01.03.2014)
Get full text
Journal Article
Carbonylhydrazide-Based Molecular Tongs Inhibit Wild-Type and Mutated HIV‑1 Protease Dimerization
Dufau, Laure, Marques Ressurreição, Ana Sofia, Fanelli, Roberto, Kihal, Nadjib, Vidu, Anamaria, Milcent, Thierry, Soulier, Jean-Louis, Rodrigo, Jordi, Desvergne, Audrey, Leblanc, Karine, Bernadat, Guillaume, Crousse, Benoit, Reboud-Ravaux, Michèle, Ongeri, Sandrine
Published in Journal of medicinal chemistry (09.08.2012)
Published in Journal of medicinal chemistry (09.08.2012)
Get full text
Journal Article
Dimer Disruption and Monomer Sequestration by Alkyl Tripeptides Are Successful Strategies for Inhibiting Wild-Type and Multidrug-Resistant Mutated HIV-1 Proteases
Bannwarth, Ludovic, Rose, Thierry, Dufau, Laure, Vanderesse, Régis, Dumond, Julien, Jamart-Grégoire, Brigitte, Pannecouque, Christophe, De Clercq, Erik, Reboud-Ravaux, Michèle
Published in Biochemistry (Easton) (20.01.2009)
Published in Biochemistry (Easton) (20.01.2009)
Get full text
Journal Article
RNA remarkably promotes HIV-1 protease fast turnover for NCp15 processing in mild acidic conditions leading to condensation of HIV-1 nucleocapsid
Lyonnais, Sebastien, Dufau, Laure, Reboud-Ravaux, Michele, Marquet, Roland, Paillart, Jean-Christophe, Gatell, Jose Maria, Gorelick, Rob, Tisné, Carine, Mirambeau, Gilles
Published in Retrovirology (19.09.2013)
Published in Retrovirology (19.09.2013)
Get full text
Journal Article
Toward the First Nonpeptidic Molecular Tong Inhibitor of Wild-Type and Mutated HIV-1 Protease Dimerization
Vidu, Anamaria, Dufau, Laure, Bannwarth, Ludovic, Soulier, Jean-Louis, Sicsic, Sames, Piarulli, Umberto, Reboud-Ravaux, Michèle, Ongeri, Sandrine
Published in ChemMedChem (08.11.2010)
Published in ChemMedChem (08.11.2010)
Get full text
Journal Article
The HIV-1 ribonucleoprotein dynamically regulates its condensate behavior and drives acceleration of protease activity through membrane-less granular phase-separation
Lyonnais, Sébastien, Sadiq, S Kashif, Lorca-Oró, Cristina, Dufau, Laure, Nieto-Marquez, Sara, Escriba, Tuixent, Gabrielli, Natalia, Tan, Xiao, Mohamed Ouizougun-Oubari, Okoronkwo, Josephine, Reboud-Ravaux, Michèle, Gatell, José Maria, Marquet, Roland, Jean-Christophe Paillart, Meyerhans, Andreas, Tisné, Carine, Gorelick, Robert J, Mirambeau, Gilles
Published in bioRxiv (26.01.2019)
Published in bioRxiv (26.01.2019)
Get full text
Paper