RIG-I-like helicases induce immunogenic cell death of pancreatic cancer cells and sensitize tumors toward killing by CD8+ T cells
Duewell, P, Steger, A, Lohr, H, Bourhis, H, Hoelz, H, Kirchleitner, S V, Stieg, M R, Grassmann, S, Kobold, S, Siveke, J T, Endres, S, Schnurr, M
Published in Cell death and differentiation (01.12.2014)
Published in Cell death and differentiation (01.12.2014)
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Journal Article
RIG-I-like helicases induce immunogenic cell death of pancreatic cancer cells and sensitize tumors toward killing by CD8+ T cells
Duewell, P, Steger, A, Lohr, H, Bourhis, H, Hoelz, H, Kirchleitner, S V, Stieg, M R, Grassmann, S, Kobold, S, Siveke, J T, Endres, S, Schnurr, M
Published in Cell death and differentiation (01.12.2014)
Published in Cell death and differentiation (01.12.2014)
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Journal Article
Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome
Bauer, Christian, Duewell, Peter, Mayer, Christine, Lehr, Hans Anton, Fitzgerald, Katherine A, Dauer, Marc, Tschopp, Jurg, Endres, Stefan, Latz, Eicke, Schnurr, Max
Published in Gut (01.09.2010)
Published in Gut (01.09.2010)
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Dissolving cholesterol crystals reduces aortic valve stenosis development in mice
Niepmann, S.T, Lenart, M, Willemsen, N, Duewell, P, Luetjohann, D, Latz, E, Nickenig, G, Zimmer, S
Published in European heart journal (01.11.2020)
Published in European heart journal (01.11.2020)
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Expression of Indoleamine 2,3-dioxygenase in erlotinib-treated patients with advanced pancreatic cancer: Translational results from a multi-center, randomized phase III trial
Kruger, S., Ormanns, S., Roesgen, V., Legenstein, M., Haas, M., Westphalen, C.B., Duewell, P., Schnurr, M., Kirchner, T., von Bergwelt-Baildon, M., Heinemann, V., Boeck, S.
Published in European journal of cancer (1990) (01.03.2019)
Published in European journal of cancer (1990) (01.03.2019)
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A novel modular platform for adoptive T cell therapy combining bispecific antibodies with synthetic agonistic receptors
Karches, C.H., Benmebarek, M., Schmidbauer, M.L., Kurzay, M., Klaus, R., Lesch, S., Cadilha, B., Rataj, F., Heise, C., Geiger, M., Murr, R., Berg, J.vom, Jastroch, M., Lamp, D., Duewell, P., Niederfellner, G., Sustmann, C., Endres, S., Klein, C., Kobold, S.
Published in European journal of cancer (1990) (01.03.2019)
Published in European journal of cancer (1990) (01.03.2019)
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Journal Article
Proof of concept and mode of action of a novel modular platform for adoptive T cell therapy combining bispecific antibodies with synthetic agonistic receptors
Karches, C., Benmebarek, M., Schmidbauer, M., Kurzay, M., Klaus, R., Geiger, M., Lesch, S., Cadilha, B., Rataj, F., Heise, C., Murr, R., vom Berg, J., Jastroch, M., Lamp, D., Duewell, P., Niederfellner, G., Sustmann, C., Endres, S., Klein, C., Kobold, S.
Published in European journal of cancer (1990) (01.03.2018)
Published in European journal of cancer (1990) (01.03.2018)
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Journal Article
Arming T cells with C-X-C-motive receptor 6 enables adoptive T cell therapy of pancreatic cancer
Lesch, S., Blumenberg, V., Stoiber, S., Ogonek, J., Cadilha, B., Dantes, Z., Rataj, F., Dorman, K., Lutz, J., Karches, C., Heise, C., Grassmann, S., Megens, R., Ruehland, S., Di Pilato, M., Pruessmann, J., Ormanns, S., Reischer, A., Duewell, P., Schnurr, M., Subklewe, M., Reichert, M., Mempel, T., Endres, S., Kobold, S.
Published in European journal of cancer (1990) (01.03.2019)
Published in European journal of cancer (1990) (01.03.2019)
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Journal Article
RIG-I-like helicases induce immunogenic cell death of pancreatic cancer cells and sensitize tumors toward killing by CD8 super(+) T cells
Duewell, P, Steger, A, Lohr, H, Bourhis, H, Hoelz, H, Kirchleitner, S V, Stieg, M R, Grassmann, S, Kobold, S, Siveke, J T, Endres, S, Schnurr, M
Published in Cell death and differentiation (01.12.2014)
Published in Cell death and differentiation (01.12.2014)
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Journal Article
Erratum: RIG-I-like helicases induce immunogenic cell death of pancreatic cancer cells and sensitize tumors toward killing by CD8+ T cells
Duewell, P, Steger, A, Lohr, H, Bourhis, H, Hoelz, H, Kirchleitner, S V, Stieg, M R, Grassmann, S, Kobold, S, Siveke, J T, Endres, S, Schnurr, M
Published in Cell death and differentiation (10.11.2014)
Published in Cell death and differentiation (10.11.2014)
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Journal Article
P06.05 IDO1-deleted CAR T cells show improved therapeutic efficacy in murine pancreatic cancer models
Senz, A M, Metzger, P, Rubens, R K, Cadilha, B, Kirmaier, M, Lesch, S, Benmebarek, M R, Theurich, S, Murray, P, Endres, S, Kobold, S, König, L M, Duewell, P, Schnurr, M
Published in Journal for immunotherapy of cancer (01.10.2020)
Published in Journal for immunotherapy of cancer (01.10.2020)
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Journal Article
P17. RIG-I-like helicases induce immunogenic cell death of pancreatic cancer cells
Schnurr, M, Steger, A, Lohr, H, Bourhis, H, Endres, S, Duewell, P
Published in Journal for immunotherapy of cancer (12.03.2014)
Published in Journal for immunotherapy of cancer (12.03.2014)
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Journal Article
P10. Concomitant gemcitabine therapy negatively affects DC vaccine-induced CD8+ T cell and B cell responses but improves clinical efficacy in a murine pancreatic carcinoma model
Bauer, C, Sterzik, A, Bauernfeind, F, Duewell, P, Conrad, C, Kiefl, R, Endres, S, Eigler, A, Schnurr, M, Dauer, M
Published in Journal for immunotherapy of cancer (12.03.2014)
Published in Journal for immunotherapy of cancer (12.03.2014)
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Journal Article
Aktivierung des Nlrp3-Inflammasoms induziert im Modell der CD45Rbhigh-Kolitis einen proinflammatorischen Phänotyp der adoptiv transferierten T-Zellen durch Vermittlung CD103+ DC
Mak'Anyengo, R, Karl, I, Duewell, P, Lehr, H, Endres, S, Schnurr, M, Bauer, C
Published in Zeitschrift für Gastroenterologie (18.08.2015)
Published in Zeitschrift für Gastroenterologie (18.08.2015)
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Conference Proceeding
RIG-I-basierte Immuntherapie des Hepatozellulären Karzinoms
Böhmer, D, Posselt, L, Lazic, I, König, L, Endres, S, Duewell, P, Mayr, D, De Toni, E, Rothenfusser, S, Schnurr, M
Published in Zeitschrift für Gastroenterologie (18.08.2015)
Published in Zeitschrift für Gastroenterologie (18.08.2015)
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Conference Proceeding
IL-18-Rezeptor-Signaling adoptiv transferierter T-Zellen reguliert die Induktion der CD4+CD45Rbhigh Transfer-Kolitis
Mak'Anyengo, R, Düwell, P, Hörth, C, Denk, G, Lehr, HA, Endres, S, Schnurr, M, Bauer, C
Published in Zeitschrift für Gastroenterologie (16.08.2016)
Published in Zeitschrift für Gastroenterologie (16.08.2016)
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Conference Proceeding
Die Immuntherapie des Pankreaskarzinoms mit Liganden von RIG-I-like Helikasen induziert eine funktionelle Umprogrammierung von myeloiden Suppressor-Zellen mit reduzierter Immunsuppression
Kirchleitner, SV, Schrom, E, Endres, S, Düwell, P, Schnurr, M
Published in Zeitschrift für Gastroenterologie (11.08.2014)
Published in Zeitschrift für Gastroenterologie (11.08.2014)
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Conference Proceeding
Aktivierung von RIG-I-like Helikasen (RLH) in Pankreaskarzinomzellen führt zu immunogenem Zelltod und Aktivierung tumorreaktiver zytotoxischer T-Zellen
Lohr, H, Bourhis, H, Beller, E, Hoves, S, Düwell, P, Schnurr, M
Published in Zeitschrift für Gastroenterologie (16.08.2013)
Published in Zeitschrift für Gastroenterologie (16.08.2013)
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Conference Proceeding
Immunogener Zelltod von Pankreaskarzinomzellen durch Liganden der zytosolischen RIG-I-like Helikasen RIG-I und MDA-5
Steger, A, Hoves, S, Düwell, P, Beller, E, Schnurr, M
Published in Zeitschrift für Gastroenterologie (09.08.2011)
Published in Zeitschrift für Gastroenterologie (09.08.2011)
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Conference Proceeding